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All Journal JURNAL PENDIDIKAN KEPERAWATAN INDONESIA AVICENNA Borobudur Pharmacy Review AKSIOMA : Jurnal Sains Ekonomi dan Edukasi Jurnal Kopendik
Eka Puspita
Jurusan Farmasi, Fakultas Kedokteran dan Ilmu-ilmu Kesehatan, Universitas Jenderal Soedirman, Purwokerto
Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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Correlation between Nutritional States with Hematological Toxicity in Children with Acute Lymphoblastic Leukemia Puspita, Eka; Mediani, Henny Suzana; Nurhidayah, Ikeu
JURNAL PENDIDIKAN KEPERAWATAN INDONESIA Vol 4, No 1 (2018): Vol 4, No. 1 (2018)
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/jpki.v4i1.12339

Abstract

ABSTRAKStatus gizi pada anak dengan acute lymphoblastic acute (ALL) diketahui dapat mempengaruhi efek samping yang mungkin timbul setelah dilakukan kemoterapi. Salah satu efek samping yang sering terjadi pada anak dengan ALL pasca kemoterapi adalah hematological toxicity. Hematological toxicity adalah efek toksik yang ditimbulkan dari obat kemoterapi yang menyebabkan gangguan pada sel darah yang bila tidak diatasi dengan baik dapat menimbulkan kematian. Hematological toxicity sering terjadi pada anak ALL pasca kemoterapi namun belum menjadi perhatian tenaga kesehatan terutama perawat. Tujuan penelitian ini adalah ingin mengetahui hubungan antara status gizi dengan hematological toxicity pada anak ALL yang sedang menjalani kemoterapi. Penelitian ini dilakukan di RSUP Dr Hasan Sadikin Bandung pada bulan Desember 2016 dengan metode penelitian korelasi dengan pendekatan retrospektif. Penelitian ini dilakukan pada 198 responden yang diambil dari catatan rekam medis bulan Januari-Juli 2016 dengan menggunakan purposive sampling. Analisa data menggunakan uji Korelasi Spearman Rank (Rho). Hasil penelitian didapatkan 13 dari 17 responden berstatus gizi sangat kurus mengalami hematological toxicity dan terdapat hubungan yang signifikan antara status gizi dengan hematological toxicity pada anak ALL (p=0,015) dengan korelasi yang sangat lemah (r=-0,172). Kesimpulan: Terdapat hubungan antara status gizi dengan hematological toxicity pasca kemoterapi pada anak LLA yang menjalani kemoterapi. Oleh karena itu, pentingnya pengkajian status gizi dan monitoring tanda-tanda hematological toxicity untuk mencegah terjadinya efek buruk akibat dari pengobatan kemoterapi pada anak dengan ALL. ABSTRACTAcute lymphoblastic leukemia (ALL) is the most common cancer in children and one of the leading causes of death in children. Many factors affect the prognosis of acute lymphoblastic leukemia, one of which is the nutritional status. Nutrition status in children with acute lymphoblastic acute is known to affect side effects that arise after chemotherapy. One of the side effects which often occur in children with ALL post chemotherapy was hematological toxicity. Hematological toxicity was one of the side effect chemotherapy if not treated properly can caused death. The aimed of this research was to analyze the correlation of nutritional status with hematological toxicity on children with ALL in chemotherapy. This study was done in Hasan Sadikin General Hospital in Bandung in December 2016 with correlational research was performed with retrospective approach. 198 respondents were selected using purposive sampling taken from medical records during January-July in 2016. Data was analyzed using Spearman Rank Correlation Test (Rho). The study showed that 17 children with ALL were categorized in very thin (86,7%) suffered from hematological toxicity thus discovered significant correlation between nutritional status pre chemotherapy and hematological toxicity post chemotherapy in children with ALL (p=0,015) for a very weak correlation (r=-0,172). The conclusion in this study researched was that nutritional stated chemotherapy was correlated with hematological toxicity after chemotherapy in children with ALL. Therefore, assessment of nutritional status in children with acute lymphoblastic leukemia should be done especially when chemotherapy treatment is being taken to minimize the occurrence of hematological toxicity 
Formulasi dan uji aktivitas salep ekstrak etanol daun kelor (Moringa oleifera L.) sebagai antibakteri Staphylococcus aureus metode Kirby bauer Puspita, Eka; Dianita, Puspita; Kusuma, Tiara
Borobudur Pharmacy Review Vol 3 No 2 (2023): August-Dec
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v3i2.8674

Abstract

Infection is the highest disease in Indonesia caused by bacteria. One of the bacteria that can cause infection is Staphylococcus aureus which is a gram-positive bacterium. Moringa leaves contain antioxidants which are secondary metabolites of catechol tannins, triterpenoid tannins, flavonoids, anthraquinone saponins, alkaloids, and reducing sugars. The purpose of this study was to determine the antibacterial activity of moringa leaf ointment (Moringa oleifera L. ) as an antibacterial for Staphylococcus aureus. This research method uses experimental. The steps that have been carried out include extraction by maceration from the simplicia powder of Moringa leaves (Moringa oleifera L. ) with 96% ethanol then in a water bath until the extract is thick. Moringa leaf ointment (Moringa oleifera L. ) with a concentration of F1 5%, F2 10%, F315% has met the requirements for good physical properties tests including organoleptic test, homogeneity test, pH, adhesion, spreadability and viscosity. The agar medium used was Nutrient Agar (Na) with the Kirby-Bauer method (Disc Diffusion) divided into 5 groups namely base, positive control, negative control, F1, F2, F3. The results of data analysis in this study used SPSS Statistics version 25 which showed a value (p> 0.05) which could be interpreted as data that there was no difference in the inhibition zone affected by Moringa leaf ethanol extract ointment against Staphylococcus aureus bacteria . The best result of the three formulas is F3 15%.
Kejadian Karies Gigi pada Tenaga Kesehatan di Rumah Sakit Puspita, Eka; Gustina, Ema; Ekawati, Dianita; Rahutami, Synthia
Avicenna: Jurnal Ilmiah Vol. 19 No. 1 (2024): Avicenna: Jurnal Ilmiah
Publisher : Public Health Department, Faculty of Health Science University Muhammadiyah Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36085/avicenna.v19i1.6468

Abstract

Background: Dental caries is a disease that is most commonly found in the oral cavity along with periodontal disease, which occurs due to demineralization of tooth surface tissue by acids produced by orgnanisms in the mouth that interact with food waste containing sugar. Its development requires a long period of time so that many sufferers are at risk of potentially lifelong disorders. The DMF-T index shows the number and level of tooth decay, which is measured using the sum of untreated cavities or caries (D), the number of teeth that have been extracted and missing teeth (M) and the number of teeth filled (F). The aims of tis study was to analyze the incidence of dental caries among health workers in hospitals. Method: this research uses a quantitative type with a descriptive analytical design using a cross sectional method. This research was carried out in February-March 2024 at Sungai Lilin Hospita, Musi Banyuasin Regency. The population in this study were health workers at Sungai Lilin Hospital in 2024 with a sample of 183 people taken using total sampling technique. Results: Data analysis was carried out univariate and bivariate using the chi-square with α=0,05. The research results showed that the knowledge variable p value = 0,011 with an OR = 2,625, frequency of tooth brushing p value = 0,000 with an OR = 8,067 and tooth brushing technique p value = 0,000 with an OR = 4,454 on the incidence of dental caries in health workers in hospitals. Conclusion: The conclusion of the research was that there was a relationship between knowledge, frequency of tooth brushing technique with the incidence of dental caries among health workers in hospitals.
RESEARCH TRENDS IN ACADEMIC PROCRASTINATION IN STUDENTS Muti'ah, Aulia; Annisa, Zakiyyah; Puspita, Eka; Haikal Afifsyah, Ahmad; Alferi, Alrefi
Jurnal Kopendik Vol 3 No 1 (2024): Maret
Publisher : Program Studi Bimbingan dan Konseling FKIP UNJA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/kopendik.v3i1.29373

Abstract

Academic procrastination is procrastination behavior that is carried out deliberately without considering the priorities that must be worked on in the academic realm. The aim of this research is to analyze the research direction of the academic procrastination variable over the last 9 years. This research method uses content analysis with samples taken from articles published on the sciencedirect, researchgate and google scholar websites. The findings of this research show that academic procrastination has internal and external factors, and has an influence on personal and learning areas. The most widely used research method is quantitative correlational. It is hoped that academic procrastination research can contribute to future researchers who wish to research academic procrastination with more varied aspects and methods.
Pengaruh Financial Distress, Ukuran Perusahaan, dan Leverage Terhadap  Manajemen Laba dengan Kepemilikan Manajerial Sebagai Variabel Moderasi pada Perusahaan Sektor Ritel yang Terdaftar di Bursa Efek Indonesia Periode 2021-2023 Puspita, Eka; Ruwanti, Gemi; Asyikin, Jumirin; Boedi, Soelistijono
AKSIOMA : Jurnal Sains Ekonomi dan Edukasi Vol. 2 No. 9 (2025): AKSIOMA : Jurnal Sains, Ekonomi dan Edukasi
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/aksioma.v2i9.1780

Abstract

This study aims to examine the effect of financial distress, firm size, and leverage on earnings management with managerial ownership as a moderating variable in retail companies listed on the Indonesia Stock Exchange during the 2021–2023 period. The research employs a quantitative approach using secondary data from annual reports and financial statements, with samples selected through purposive sampling, resulting in 57 observations from 43 companies. Data were analyzed using multiple linear regression and moderated regression analysis (MRA) with SPSS 25. The findings reveal that financial distress and leverage have no significant effect on earnings management, while firm size shows a significant positive influence on earnings management. Furthermore, managerial ownership does not moderate the relationship between financial distress, firm size, and leverage with earnings management. These results indicate that firm size plays a dominant role in driving earnings management practices, while relatively small managerial ownership has not been sufficient to act as an effective control mechanism. Therefore, companies are advised to maintain transparency in financial reporting, and investors are encouraged to consider firm size and ownership structure when assessing earnings quality.
Co-Authors Alferi, Alrefi Annisa, Zakiyyah Boedi, Soelistijono Dhadhang Wahyu Kurniawan Dianita Ekawati Dianita, Puspita Gustina, Ema Haikal Afifsyah, Ahmad Henny Suzana Mediani Ikeu Nurhidayah Jumirin Asyikin Kusuma, Tiara Muti'ah, Aulia Rahutami, Synthia Ruwanti, Gemi Teuku Nanda Saifullah Sulaeman, Teuku Nanda Saifullah