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Rapid Cycling Bipolar and Trauma-Related Personality Traits: Bridging the Gap Between Affective Dysregulation and Early-Life Adversity Septina, Egy Atthahirah; Halimatus Sakdyah; Pramesta, Linda Ramadhanty; Muhammad Ikhsan; Alsa Shafira; Budi Cahyono; Hafid Algristian
Medicor : Journal of Health Informatics and Health Policy Vol. 3 No. 1 (2025): January 2025
Publisher : Indonesian Scientific Publication

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61978/medicor.v3i1.740

Abstract

Rapid cycling bipolar disorder (RCBD) represents a severe and treatment-resistant subtype of bipolar disorder in which patients experience at least four mood episodes within a year, often accompanied by greater psychiatric comorbidity, functional impairment, and suicide risk compared to non-rapid cycling cases. Childhood trauma and early-life adversity have been identified as critical contributors to emotional dysregulation, impulsivity, and treatment resistance, yet their role is frequently underrecognized in clinical practice. This case report describes a 30-year-old woman diagnosed with RCBD and a history of emotional and physical abuse in childhood, aiming to illustrate the complex interaction between trauma and affective instability while integrating neurobiological, psychological, and clinical perspectives. The patient underwent four weeks of inpatient evaluation that included structured interviews, collateral history from caregivers, psychometric assessments using the Young Mania Rating Scale (YMRS), Hamilton Depression Rating Scale (HAM-D), and Difficulties in Emotion Regulation Scale (DERS), as well as daily multidisciplinary observation. Over the past year, she experienced six distinct mood episodes with severe deficits in emotional clarity and impulse control, elevated DERS scores, and only partial response to pharmacological treatment with valproate and quetiapine. Clinical patterns and supporting literature suggest that trauma-induced dysregulation, involving amygdala hyperactivation and hypothalamic–pituitary–adrenal (HPA) axis disruption, played a central role. Improvement was achieved only after trauma-focused psychotherapy and psychosocial support were incorporated into her care. This case highlights the necessity of early trauma screening and integrative, trauma-informed management to improve diagnostic accuracy, treatment engagement, and long-term outcomes in complex bipolar presentations.
Anhedonia is a Symptom of Severe Depression and Generalized Anxiety Disorder Akhmad Vauwaz Z H; Nur Azizah; Hafid Algristian
Jurnal Riset Kualitatif dan Promosi Kesehatan Vol. 5 No. 1 (2026): January 2026
Publisher : Yayasan Sinergi Kawula Muda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61194/jrkpk.v5i1.851

Abstract

Anhedonia, defined as the reduced ability to experience pleasure, is a core symptom of major depressive disorder (MDD) and is increasingly recognized as a transdiagnostic marker that bridges depressive and anxiety disorders. This report presents the case of a 16-year-old Indonesian girl who exhibited pervasive sadness, irritability, fatigue, and marked anhedonia characterized by complete disengagement from competitive swimming, a central aspect of her self-identity. Psychosocial stressors, including parental conflict and academic pressure, preceded the escalation of symptoms. Clinical assessment revealed a severe depressive episode, with a Hamilton Depression Rating Scale (HDRS) score of 24 and significant anhedonia confirmed by the Snaith–Hamilton Pleasure Scale (SHAPS). Neurological and laboratory examinations were unremarkable. The patient was diagnosed with severe MDD (F32.2) and comorbid generalized anxiety disorder (F41.1) according to PPDGJ-III and DSM-5 criteria. Treatment included sertraline (up to 50 mg/day), short-term clobazam, and supportive psychotherapy with family intervention. At four-week follow-up, depressive symptoms improved, accompanied by partial recovery of motivation and social engagement. This case highlights anhedonia as a clinically prominent and functionally impairing symptom in adolescent depression and anxiety. Beyond its emotional dimension, anhedonia reflects a disruption of reward processing that contributes to poor academic, social, and developmental outcomes. Routine assessment of anhedonia using structured instruments such as SHAPS and culturally sensitive interviews may improve diagnostic precision and guide personalized treatment. Early detection and integrative interventions—combining pharmacological, psychotherapeutic, and family-based approaches—are essential for optimizing recovery and preventing long-term disability in adolescent mood disorders.
Inovasi Pemberdayaan Masyarakat: Pencegahan Stunting dan Tuberkulosis di Desa Roomo dengan Ikan Laut dan Virgin Coconut Oil Mulyadi; Wiwik Winarningsih; Chilyatiz Zahroh; Hafid Algristian; Mufidah Sheena Andani Prastini; Kunti Fatimah Azzahro; M. Djali Yusup Iskandar Muda
Journal of Community Development Diversity Vol. 1 No. 1 (2025): Maret
Publisher : PT Pro Panoramic Solution

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64595/jcdd.152

Abstract

Prevalensi stunting di Jawa Timur pada tahun 2022 mencapai 23,5%, lebih tinggi dari target WHO sebesar 20%. Stunting pada balita berdampak tidak hanya pada pertumbuhan fisik, tetapi juga meningkatkan risiko penyakit seperti tuberkulosis (TB). Penelitian menunjukkan bahwa balita dengan status gizi stunting berisiko 2,96 kali lebih tinggi terkena TB, sementara balita dengan severely stunting memiliki risiko 8,18 kali lebih tinggi. Di Desa Roomo, Kabupaten Gresik, penanganan stunting dan TB masih terbatas, khususnya terkait pemenuhan gizi seimbang untuk ibu dan anak. Oleh karena itu, kegiatan pengabdian masyarakat ini bertujuan untuk meningkatkan partisipasi masyarakat dalam pencegahan stunting dan TB secara berkelanjutan melalui pemanfaatan modul terapan. Metode yang digunakan adalah pemberdayaan kader desa, edukasi masyarakat, serta distribusi makanan tambahan (PMT) berbasis ikan laut dan virgin coconut oil (VCO). Kegiatan ini dilakukan dengan melibatkan RS Graha Husada Gresik dan kelompok nelayan Gresik Utara. Hasil menunjukkan adanya peningkatan berat badan anak sebesar 0,5 hingga 1 kg, serta peningkatan pengetahuan kader desa dan masyarakat tentang pencegahan stunting dan TB. Kader yang telah dilatih berhasil menjalankan perannya dalam memantau pemberian PMT dan memberikan edukasi kesehatan. kegiatan ini berhasil meningkatkan status gizi anak dan memberdayakan kader desa dalam mendukung program pencegahan stunting dan TB. Keberlanjutan program ini diharapkan mampu menurunkan prevalensi stunting dan TB di Desa Roomo melalui Posko Tanggap Stunting dan TB Anak yang aktif digunakan untuk pemantauan kesehatan.
Switching from Antipsychotic Polypharmacy to Monotherapy in Hebephrenic Schizophrenia: A Case Study Silaban, Rusdiana; Nur Azizah; Hafid Algristian
Journal of Health Literacy and Qualitative Research Vol. 6 No. 1 (2026): March 2026
Publisher : Yayasan Sinergi Kawula Muda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61194/jhlqr.v6i1.905

Abstract

Schizophrenia is a chronic psychiatric disorder that imposes a substantial burden on patients and caregivers. Antipsychotic polypharmacy remains a common clinical practice to manage persistent positive and negative symptoms, although growing evidence indicates it does not significantly improve treatment outcomes and may instead increase adverse effects, treatment costs, and non-adherence. This case study aimed to describe the clinical benefits and rational considerations of switching from antipsychotic polypharmacy to monotherapy in a patient with hebephrenic schizophrenia. A 37-year-old woman with a 20-year history of hebephrenic schizophrenia was observed. She had previously received a combination of chlorpromazine and trifluoperazine with trihexyphenidyl for extrapyramidal symptom prevention. Clinical evaluations were performed to assess therapeutic effects, side effects, and medication adherence before and after the switch to chlorpromazine monotherapy. During the polypharmacy phase, the patient experienced several side effects, including insomnia, restlessness, irritability, and mild extrapyramidal symptoms. After transitioning to monotherapy with an adjusted chlorpromazine dose, she showed notable improvement in psychotic symptoms, sleep quality, and social functioning without severe adverse reactions. Medication adherence increased as the patient reported greater comfort and tolerance with a single-drug regimen. This case suggests that switching from antipsychotic polypharmacy to monotherapy can reduce side effects, improve adherence, and maintain clinical stability. Rational and individualized use of antipsychotics should be prioritized to achieve better long-term outcomes and quality of life in schizophrenia management.
Beyond Profit and Stress: Spirituality as a Bridge Between Business and Psychiatry in the Startup Era Maulidatul Jinani Firdausyah; Nur Azizah; Hafid Algristian
Jurnal Riset Kualitatif dan Promosi Kesehatan Vol. 5 No. 1 (2026): January 2026
Publisher : Yayasan Sinergi Kawula Muda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61194/jrkpk.v5i1.902

Abstract

Micro and small-scale digital startups face intense psychological and operational pressures that often result in burnout, chronic stress, and adjustment problems. Yet, mental health issues within startup ecosystems remain insufficiently addressed and lack structured intervention. This literature review synthesizes cross-disciplinary studies published between 2013 and 2025 to examine how workplace spirituality can be integrated into startup work culture and its potential application within community psychiatry. The review indicates that workplace spirituality enhances mental well-being, reduces stress symptoms, and strengthens resilience, functioning as a psychological buffer for entrepreneurs facing high uncertainty. Spirituality also provides a conceptual bridge between managerial and clinical perspectives, enabling more holistic and human-centered approaches to mental health in startup environments. Integrating spiritual values into entrepreneurial settings emerges as an effective non-clinical strategy to sustain founders' mental health and expand opportunities for contextual community psychiatry interventions. The novelty of this study lies in its cross-disciplinary mapping that links startup management, spiritual psychology, and community psychiatry into a practical and preventive intervention framework.