Article Per Year (5 Year)
p-Index From 2021 - 2026
1.347
P-Index
This Author published in this journals
All Journal Damianus Journal of Medicine The Indonesian Biomedical Journal Majalah Anestesia dan Critical Care Indonesian Journal of Perinatology Jurnal Neuroanestesi Indonesia Medical Clinical Update Journal
Theresia Monica Rahardjo
Faculty Of Medicine, Maranatha Christian University, Bandung, West Java, Indonesia
Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

Published : 12 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : The Indonesian Biomedical Journal

 1 
Propofol Effect on Stress Response and Free Radicals in Patient during Surgery and Sedation Procedure Theresia Monica Rahardjo
The Indonesian Biomedical Journal Vol 7, No 3 (2015)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v7i3.183

Abstract

BACKGROUND: Propofol is an intravenous anesthetic used worldwide as an anesthesia induction and maintenance agent. Propofol also used as sedation agent in Intensive Care Unit (ICU). Despite it’s usual anesthesia properties, propofol has an unique pharmacologic characteristic, especially as antioxidant and stress response reduction. These advantages suggested propofol has positive effects when used as an anesthesia agent in surgery or sedation in ICU in conditions when high stress and free radical level are released.CONTENT:Stress response and free radical can be elevated in various conditions including surgery or during care in ICU, especially critical ill patient. Cortisol is a major stress hormone that influences metabolism, cardiovascular and central nervous system, either in acute or chronic phase. Oxidative stress was marked by free radical elevation called Radical Oxygen Species (ROS). Combination of both elements (cortisol and ROS) can worsen patient condition. Propofol with anti-stress and antioxidant properties could be used to reduce stress response and attenuate free radical level in order to improve patient condition.SUMMARY: The anti-stress and antioxidant properties of Propofol are interesting, because these benefits can be added as adjunctive therapy when propofol was used as an anesthetic agent in surgery and a sedation in ICU.KEYWORDS: propofol, stress response, antioxidant
The Role of Free Radicals and Antioxidant in Abortion Aloysius Suryawan; Theresia Monica Rahardjo
The Indonesian Biomedical Journal Vol 5, No 1 (2013)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v5i1.47

Abstract

BACKGROUND: Free radicals and antioxidant exist in balance under normal condition. In prooxidant condition, excessive free radicals can initiate a state of oxidative stress (OS) followed by capillary endothelial cell damage, a process involved in the pathophysiology of abortion.CONTENT: Abortion is a common complication of pregnancy and occurs in 25% of women. Many factors can cause abortion including fetal factor, implantation process and hormonal status. Combination those factors with OS influence the entire reproductive life of a woman. Antioxidant can neutralize free radicals and used to reduce OS especially in recurrent abortion.SUMMARY: Antioxidant therapy is a very interesting field in abortion especially used as prevention approach mainly caused by the high cost of infertility treatment methods.KEYWORDS: free radical, antioxidant, abortion
Co-Authors Aldiansyah, Dudy Aldika Akbar, Muhammad Ilham Aloysius Suryawan Aloysius Suryawan Anastasia Nadya Andonotopo, Wiku Andrieta Berliana Marzani Angelica Rosa Septiana Hartono Anisya Lisna Bachnas, Muhammad Adrianes Bambang Rahardjo Chris Monalisa Christina Pretaliana Cindy Thalia Putri Cut Meurah Yeni Epi Panjaitan Eqen Desmonta Evert Solomon Pangkahila Fadhilla Liefya Zahraisha Henry Theo Prawira Sugitto I Nyoman Hariyasa Sanjaya Ivanna Sarahfebi Iwan Fuadi Jeffrey Christian Mahardhika Jessica Natasya Julian Dewantiningrum Kevin Axel Kevin Hersan Kurjak, Asim Liyenka Belusi Tantra Monica Monica, Monica Nabilla Aisya Zhavira Nafthalena Nathalia Gabriella Novinka Iriane Nuswil Bernolian Parbati Anjali Peter Nugraha Soekmadji Pramono, Mochammad Besari Adi Putu Intan Kusuma Wardani Rizna Tyrani Rumanti Ryan Saktika Mulyana Sheila Meriyani Sri Sulistyowati Stanojevic, Milan Steffi, Steffi Stephanie Astrid Gunawan Tatang Bisri Valentine Natasya Moenardi Vannesa Shelly Varda Natasya Hutapea Wargahadibrata, Himendra Wiradnyana, Anak Agung Gede Putra Yoctaf Octora Kadam Zarahnaya Putri