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All Journal Medical Journal of Indonesia Jurnal Respirologi Indonesia Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Respiratory Science eJournal Kedokteran Indonesia
Menaldi Rasmin
Department Of Pulmonology And Respiratory Medicine Faculty Of Medicine, Universitas Indonesia
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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The Role Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome Widhy Yudistira Nalapraya; Menaldi Rasmin; Zuswayudha Sjamsu
Jurnal Respirologi Indonesia Vol 43, No 1 (2023)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v43i1.436

Abstract

Treatment of oxygen therapy should be based on appropriate indication and dose of administration. British Thoracic Society (BTS) recommends oxygen therapy were administered with a 94–98% saturation target in most acute patients and for patients with hypercapnic respiratory failure, BTS recommends 88-92 saturation target or spesific saturation target. Acute respiratory distress syndrome (ARDS) is characterized by acute, diffuse, inflammatory lung injury leading to increased capillary permeability in the alveolus with clinical manifestations of hypoxemia and bilateral opafication. The use of extracorporeal membrane oxygenation (ECMO) along with mechanical ventilator can be useful for ARDS patients and can improve survival.
Gut-Lung Axis Anggie Indari; Menaldi Rasmin; Ari Fahrial Syam
Respiratory Science Vol. 3 No. 2 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v3i2.68

Abstract

Microbiota and the body's immune system have a two-way interaction that is interconnected. The microbiota plays a role in the formation and maturation of the immune system, on the other hand, the immune system shapes the composition and function of the microbiota. This interaction is important in maintaining the body’s immune system’s homeostasis. The human intestine contains various types of microbes that form the gut microbiota. Various studies have found that changes in the gut microbiota are associated with immunity in distal tissues such as the lung. This gives rise to the concept of a feedback relationship between the gut and lung organs called the gut-lung axis. Through this axis, changes in the composition of the gut microbiota not only cause abnormalities in the gut but also affect microbiota in the lungs and can cause disease. One of the important routes in the transmission of substances from the intestine is through the mesenteric lymphatics. Probiotics can help improve the gut’s defense mechanism. A high-fiber diet can also reduce pathogenic bacteria by increasing levels of short-chain fatty acids. Therefore, a healthy lifestyle is needed to maintain the balance of the microbiota.
Relationship Between Nutritional Status, Physical Activity, Type of Work and Smoking Activity with Fitness Level Measured by 6-Minute Walking Test on Non-staff Employees of Universitas Indonesia, Depok Menaldi Rasmin; Hilma Nur Faiza; Kemal Akbar Suryoadji; Neny Husnaini Zain; Sakinasha Siva Utami; Feni Fitriani Taufik; Dewi Friska; Nani Cahyani Sudarsono; Elisna Syahrudin
Respiratory Science Vol. 3 No. 2 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v3i2.70

Abstract

Background: Fitness is inextricable to health and has a significant correlation with the habits and behaviour of individuals such as dietary practice, sedentary behaviour, physical activities, and smoking habits. Many ways can be used to assess an individual fitness level, one of them is using the 6-minute walking test. This study aims to find the correlation between smoking intensity, nutritional status, occupation, and physical activity with the fitness level of outdoor janitors in Universitas Indonesia, Depok. Method: The research method was the cross-sectional design. The determination of the subjects was carried out by a consecutive sampling method. The data obtained results from the assessment of nutritional status, occupation, physical activity, and smoking intensity, as well as result from the 6-minute walking test. Univariate data analysis was used to assess the distribution of subjects based on sociodemographics, nutritional status, physical activity, occupation, and smoking activity. Furthermore, categorical correlative tests used were Man-Whitney, Kruskal-Wallis, and Fisher's Exact test. Results: The subjects obtained are 109 outdoor janitors from UI, Depok in which 59.6% age 18-44 years old, and 56% are male. Based on the correlative test between the fitness level and the nutritional status, value of P=0.086, as value of P between the physical activity and the fitness level is 0.0523. No significant correlation between fitness level and occupation based on location of the job, duration of work and based on the work time (P=1.00; P=1.00; P=0.108) The correlation between smoking intensity with the fitness level has value of P=0.681. Conclusion: There is no significant correlation between nutritional status, physical activity, type of work, and smoking intensity with the fitness level as measured by the 6-minute walking test method for outdoor janitors of UI, Depok.
Magnesium and Phosphate Ion Levels in Mechanically Ventilated Patients Treated at Persahabatan Hospital’s Intensive Care Unit (ICU) and Respiratory Intensive Care Unit (RICU) in 2018 Filemon Suryawan Handjaja; Menaldi Rasmin; Prasenohadi Prasenohadi; Ernita Akmal
Jurnal Respirologi Indonesia Vol 43, No 3 (2023)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v43i3.456

Abstract

Background: History shows that respiratory system has a long and complicated arrangement so that many factors can affect a human’s ability to breathe. Some electrolytes often considered as most important are sodium (Na+), potassium (K+), calcium (Ca2+) and chloride (Cl-). Other than that, magnesium (Mg2+) and phosphate (PO43-) are also important in all processes, especially at the neuromuscular junction and in muscle cells as adenosine triphosphate (ATP). Some researchers have found that PO43- affected patients’ clinical condition and ventilator weaning success, although Mg2+ gave inconsistent results. Until now, there have not been any studies or data about the significance of Mg2+ and PO43- in ventilator weaning in Indonesia.Methods: This was a cross sectional study with total sampling. A vein blood sample was taken after ICU/RICU admission at Persahabatan Hospital. Blood sample was taken consecutively until it reached a minimum of 30 subjects (pilot study). All patients found with mechanical ventilation were included, except for patients with complicated procedure (e.g. avian influenza, multidrug-resistant tuberculosis). Blood sample was analyzed for Mg2+, inorganic phosphate (Pi) and other additional tests. Failure in weaning was defined as reintubation within 48 hours after extubation or failure in the spontaneous breathing trial (SBT).Results: Of the 31 subjects evaluated, there were 3 patients with weaning failure. The median Mg2+ value was 0.5 (0.5-2.6) in successfully weaned patients and 0.6 (0.6-2.7) in patients with weaning failure, lower than its normal value. The mean Pi value was 4.21±1.17 (normal value) in successfully weaned patients and 5.43±0.47 (high value) in patients with weaning failure. Further analysis found that no significant relation was found between weaning and patient’s characteristics other than heart rate and Ca2+, although it was not clear if there were some biases which could affect these results. Low Mg2+ value was observed in 23 subjects, no low Pi value was seen in all subjects, high Mg2+ value was found in 1 subject, high Pi value was observed in 11 subjects, and the rest was in the normal range.Conclusion: The median Mg2+ value in both weaning groups (successful and failed) were below the normal limit at 0.5 (0.5-2.6) and 0.6 (0.6-2.7). Mean Pi value in the successful weaning group was 4.21±1.17 (within normal range), and the value in failed weaning group was 5.43±0.47 (above normal range).
Continuing Monitoring in Respiratory Intensive Care Unit and Mortality in Patient Post Bronchoscopy Procedure Vina Fiqria; Kevin Aristyo; Rasmin Menaldi
Respiratory Science Vol. 4 No. 1 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i1.92

Abstract

Background: Bronchoscopy is a relatively safe procedure in the diagnosis and therapy of lung disease, however in some cases complications can occur which lead to further monitoring in the intensive care or respiratory intensive care unit (RICU) and even lead to mortality. This study aimed to determine the need for intensive care unit monitoring and the risk factors that increase the need for intensive care unit monitoring followed by mortality after bronchoscopy procedure. Method: A retrospective data of consecutive bronchoscopy procedures in Persahabatan Hospital between July to December 2021. Results: From 410 patients underwent bronchoscopy procedures, there were 52 patients (12.6%) were admitted to RICU after bronchoscopy. From patients who were treated in RICU 3 (5.8%) of them died. Patients who died during monitoring in intensive care unit had an older mean age of 60.3 years. There were 2 (12.5%) died after bronchoscopy procedures with two or more intervention, 1 patients (3%) died in the group with one intervention. There were 2 patients (13.3%) died with two or more comorbidities and 1 patient (5.9%) died with one comorbid. In the group with diagnosis of malignancy, 3 patients (7.5%) died. Whereas in patients who were performed surgery during bronchoscopy there were 2 patients (20%) died and only 1 patient (2.4%) died without any surgery during bronchoscopy. Conclusion: Although bronchoscopy is a relatively safe procedure but the need of monitoring in intensive care after bronchoscopy procedures were relatively high and mortality quite high compare to previous study. Further research is needed to determine the risk factors that increase the need of continuing monitoring in intensive care unit followed by mortality after bronchoscopy procedure.  
Mobilisasi Tenaga Medis Dalam Menghadapi Pandemi COVID-19 Siti Chandra Widjanantie; Falah Kartikawati; Tri Apriliawan Bendarto Rahardjo; Agus Dwi Susanto; Erlina Burhan; Thariq Emyl Taufik Hasibuan; Rita Rogayah; Menaldi Rasmin
Majalah Kedokteran Indonesia Vol 70 No 8 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.8-2020-267

Abstract

Seiring masuknya covid-19 ke tanah air yang kemudian menjadi bencana wabah sehingga infeksi meluas secara cepat dengan fatalitas yang terbatas, cukup membuat kewalahan pelayanan kesehatan. Terbitnya Surat Keputusan Konsil Kedokteran Indonesia Nomor 18/KKI/KEP/III/2020 tentang Kewenangan Dokter Penanggung Jawab Penanganan Pasien di Fasilitas Pelayanan Kesehatan Pada Masa Darurat Bencana Wabah Penyakit Akibat Corona Virus Disease 2019 (COVID-19) di Indonesia mengijinkan mobilisasi seluruh tenaga medis dan spesialis baik paru dan non paru di saat pandemi covid guna mencukupi layanan covid, menjadikan dasar bagi RSUP. Persahabatan yang ditunjuk sebagai rumah sakit khusus covid untuk menerapkan hal tersebut.
The Evolution of Transbronchial Lung Biopsy Guidance Alatas, Mohammad Fahmi; Bies, Asri Liqditta; Prasenohadi, Prasenohadi; Soehardiman, Dicky; Aniwdyaningsih, Wahju; Elhidsi, Mia; Desianti, Ginanjar Arum; Reisa, Tina; Rasmin, Menaldi
Respiratory Science Vol. 5 No. 2 (2025): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v5i2.170

Abstract

Histological confirmation of lung lesions is necessary prior to determining further management. Imaging preparation is needed to find the biopsy site such as a computed tomography scan. Imaging helps to trace the position of lung lesions that are peripheral and not visualized by bronchoscope. However, along with the discovery of small lesions and peripheral location, two-dimensional imaging alone remains suboptimal. Therefore, to reach lung lesions peripherally would need to a guide through the bronchial. Subsequently, the method of guiding transbronchial biopsy evolved. Namely, real-time fluoroscopy, radial-probe endobronchial ultrasound, virtual bronchoscopy navigation and electromagnetic bronchoscopy navigation are guiding modalities with each of their advantages and disadvantages. Several biopsy modalities are used in combination to increase the accuracy of diagnosis. Careful analysis in planning and an understanding of the limitations and advantages of diagnostic modalities must be considered in deciding which method to choose.
Co-Authors Adang Bachtiar Agus Dwi Susanto Alatas, Mohammad Fahmi Andre Prawira Putra Anggie Indari Aniwdyaningsih, Wahju Anwar Jusuf Ari Fahrial Syam Arifin Nawas Bies, Asri Liqditta Budhi Antariksa Desianti, Ginanjar Arum Desilia Atikawati Dewi Friska Dian Megawati Diyan Ekawati Elhidsi, Mia Elisna Syahrudin Erlina Burhan Ernita Akmal Faisal Yunus Faisal Yunus Falah Kartikawati Fanny Michelle Filemon Suryawan Handjaja Hadiarto Mangunnegoro Hilma Nur Faiza Ika Yunita Sari Kemal Akbar Suryoadji Kevin Aristyo Nani Cahyani Sudarsono Nani Cahyani Sudarsono Neny Husnaini Zain Nina Aspiah Novita Maulidiyah Prasenohadi Prasenohadi Prasenohadi Prasenohadi Prasenohadi, Prasenohadi Pusparini Kusumajati Putri Suci Ratnawati Antaria Reisa, Tina Risa Febriana Rita Rogayah Sakinasha Siva Utami Siti Chandra Widjanantie Soehardiman, Dicky Sri Indah Indriani Sri Wening Pamungkasningsih Steven Jonathan Taufik, Feni Fitriani Thariq Emyl Taufik Hasibuan Tri Apriliawan Bendarto Rahardjo Vina Fiqria Wahju Aniwidyaningsih Widhy Yudistira Nalapraya Wirya Sastra Amran Wiwien H. Wiyono Zuswayudha Sjamsu