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All Journal Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Respiratory Science eJournal Kedokteran Indonesia Cermin Dunia Kedokteran
Menaldi Rasmin
Department Of Pulmonology And Respiratory Medicine Faculty Of Medicine, Universitas Indonesia
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Failure of Breathing in Heavy Preeklampsia With Peripartum Cardiomiopathy Desilia Atikawati; Diyan Ekawati; Pusparini Kusumajati; Prasenohadi Prasenohadi; Menaldi Rasmin
Jurnal Respirologi Indonesia Vol 37, No 4 (2017)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (514.006 KB) | DOI: 10.36497/jri.v37i4.88

Abstract

Physiological alterations during pregnancy generate higher risk of pulmonary edema and acute respiratory failure. Respiratory failure occurs in 0.2% pregnancy, particularly in postpartum period. Respiratory failure can be developed by specific conditions related to pregnancy, such as preeclampsia and peripartum cardiomyopathy. We present the case of 34-year-old female, with 36 weeks of pregnancy, that came with shortness of breath since an hour before admitted. Patient also had vaginal discharge in the last two hours before admitted. Fetal movement was active. Shortness of breath was accompanied with cough. Physical examination revealed hypertension (160/110 mmHg) and rales on both lungs. Blood gas analysis showed severe hypoxemia. Patient were intubated and underwent C-section afterwards. Chest x-ray showed heart enlargement. Echocardiography result showed fraction ejection 25%, global hypokinetic, mild mitral and tricuspid regurgitation, with conclusion of peripartum cardiomyopathy. This case illustrates respiratory failure in severe preeclampsia and peripartum cardiomyopathy. This condition leads to acute pulmonary edema that impairs ventilation/perfusion process. Mechanical ventilation can assure adequate oxygen delivery. Non-invasive ventilation (NIV) is well suited to short-term ventilatory support, and avoids the potential complications of endotracheal intubation and the associated sedation. (J Respir Indo. 2017; 37(4): 325-36)
Hypoxemia Event and Related Factor on Diagnostic Bronchoscopy for Lung Tumor Case Andre Prawira Putra; Menaldi Rasmin; Wahju Aniwidyaningsih
Jurnal Respirologi Indonesia Vol 40, No 2 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v40i1.93

Abstract

Background: Bronchoscopy is a commonly medical procedure perfomed for diagnose lung tumor cases. Hypoxemia often appear as complication related diagnostic bronchoscopy. Therefore, there is a need of research data to knowing related factors and clinical consequences may occur ahead. Methods: Design of this study is cross sectional with suspicion lung malignancy population who undergoing diagnostic bronchoscopy from January until april 2019 at National Respiratory Center Persahabatan General Hospital Jakarta. Total 195 consecutive patients participated dan observed for oxygen saturation in premedication, during and post-bronchoscopy. Hypoxemia was defined as a desaturation
Respiratory Failure in Pneumonia with Diabetic Ketoacidosis (DKA) Novita Maulidiyah; Sri Indah Indriani; Prasenohadi Prasenohadi; Menaldi Rasmin
Jurnal Respirologi Indonesia Vol 38, No 1 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v38i1.140

Abstract

The annual incidence rate of KAD is estimated to be between 4.6 and 8 per 1000 patients with diabetes. Based on the results of the physical examination, the patient was diagnosed as pneumonia with KAD. The mortality rate for community pneumonia on outpatients was 2%, inpatients was 5-20%, more so in patients in intensive care that was more than 50%. The problem in the patient is pneumonia. Resulting in pulmonary dysfunction which causes overload. Infections that can increase morbidity and mortality may be associated with Streptococcus infection (group B, S, pneumonia), Legionella and viral infections (influenza). The most common infections are pneumonia and urinary tract infections which account for between 30% and 50% of cases. Therefore, the choice of empiric antimicrobial therapy in diabetic patients with evidence of staphylococcal pneumonia (consistent with sputum smear results or associated soft tissue infection) should be guided by the prevalence of MRSA in the associated institutions. Respiratory failure is a complication of KAD and increases the mortality rate. and morbidity. Based on the high nasal carriage rate, there is an increased risk of staphylococcal pneumonia infection in diabetic patients. Community pneumonia is acute inflammation due to infection of the lung parenchyma acquired in the community. (J Respir Indo 2018; 38(1): 57-63)
Mechanical Ventilation in Non Lung-Post Surgery Patients Ika Yunita Sari; Sri Wening Pamungkasningsih; Menaldi Rasmin
Jurnal Respirologi Indonesia Vol 38, No 3 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (730.714 KB) | DOI: 10.36497/jri.v38i3.9

Abstract

A case of a 41-year-old man, with a lump in his left abdomen since 5 months before admission to the hospital. In the last 2 weeks the patient complained of reddish urine and pain during urination. The diagnosis of the patient is a left kidney tumor, has performed nephrectomy and splenectomy surgery. Postoperative complications include sepsis, anemia and hypoalbuminemia. Sepsis in these patients is caused by colonic perforation leading to intra-abdominal infection. These complications cause patients to get treatment in the intensive care unit longer by using a ventilator for four days.
Breath Failure in Obesity Wirya Sastra Amran; Putri Suci; Nina Aspiah; Menaldi Rasmin; Prasenohadi Prasenohadi; Agus Dwi Susanto
Jurnal Respirologi Indonesia Vol 38, No 2 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v38i2.167

Abstract

Based on calculations of over one million people in the world weighing excessively or known as obesity with body mass index (IMT) 25 kg / m2 or more. Obesity is the cause of morbidity, as is the case in the population of the United States an estimated 400,000 deaths caused due to obesity. Obesity especially abdominal obesity is a significant risk factor for cardiovascular diseases, type 2 diabetes, rheumatoid arthritis and cancer. The relationship between obesity and chronic respiratory illness began to increase and began to be recognized. The World Health Organization (WHO) predicts about 10% of the global population will be obese by 2015. (J Respir Indo 2018; 38(2): 123-33)
Multiple Possible Causes Of Dyspnea In An Unusual Pickwickian Syndrome On Covid-19 Pandemic: A Case Study Steven Jonathan; Menaldi Rasmin
Respiratory Science Vol. 2 No. 2 (2022): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i2.44

Abstract

Introduction: Pickwickian Syndrome (PS) or obesity hypoventilation syndrome (OHS) is a diagnosis of exclusion with features of obesity, sleep disordered breathing, and chronic daytime hypercapnia. Patients with PS could present into general OSA or respiratory failure. We are presenting an unusual case of PS with acute respiratory failure resulting in organ failure and mortality. Case report: A 41-year-old male was admitted to hospital due to shortness of breath. He had a trouble sleeping; frequently awoke as the breathing briefly stopped and gasping. There were history of diabetes melitus (DM) and hypertension for >10 years, smoking with moderate Brinkman Index. Patient appeared to have somnolence, tachypnea, hypoxemia, morbid obesity. We assessed him as PS, bronchopneumonia, respiratory failure, pulmonary edema, hypertensive heart disease (HHD), DM, acute on CKD. We managed him with pharmacotherapy, oxygen (BiPAP), and hemodialysis. After transferred from ICU to regular ward, patient was suddenly apneic and CPR was performed; ended in mortality. Discussion: This unusual case (malignant OHS) was a subgroup among OHS with greater morbidity and multiorgan system dysfunction. There were multiple causes of dyspnea on our patient which concluded to a death case. There are three modalities of management in stable PS: positive airway pressure (PAP), weight reduction, and pharmacotherapy. The management of respiratory failure in PS mainly involved oxygen therapy in positive pressure. Conclusion: There were multiple causes of dyspnea in this patient. Optimal management of patient ought to treat not only the PS but also all the comorbidities.
Preoperative Assessment Prior to Lung Resection: How to Eliminate the Risk Dian Megawati; Menaldi Rasmin; Budhi Antariksa; Faisal Yunus
Respiratory Science Vol. 2 No. 3 (2022): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i3.48

Abstract

Lung resection is part of the treatment of various lung diseases, both malignancy and infection. Although it has great benefits, lung resection can result in a variety of functional disorders that can affect the whole cardiopulmonary system. The mortality of these procedures is 2-4% in segmentectomy and 6-8% in lobectomy, while the mortality of pneumonectomy in the world is 11%. Good preoperative assessment of patients has been reported to have reduced mortality and morbidity after lung resection. Things that need to be considered to assess preoperative eligibility include age, lung function, cardiovascular fitness, nutrition, and performance status. The preoperative pulmonary tolerance assessment is divided into three stages: the first stage is the assessment of lung function and blood gas analysis, the second stage is to assess postoperative prediction of pulmonary function, and the third stage is to assess the maximum oxygen consumption per minute by doing a cardiopulmonary exercise test. Patients who have a good tolerance for lung resection are patients who have predictive postoperative force expiration volume one second (ppoFEV1) values more than 40%, predictive postoperative diffusion capacity of the lung for carbon monoxide (ppoDLCO) more than 50%, and maximum oxygen consumption (VO2 max) more than 15ml/kg/min.
Pengetahuan dan Perilaku Mahasiswa Tingkat Akhir FKUI terhadap COVID-19 pada Tahun Ajaran 2020/2021 Fanny Michelle; Menaldi Rasmin
eJournal Kedokteran Indonesia Vol 9, No. 3 - Desember 2021
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (191.571 KB) | DOI: 10.23886/ejki.9.94.213-9

Abstract

COVID-19 adalah penyakit pernapasan akibat SARS-CoV-2 yang merupakan pandemi dunia. Dalam menghadapi COVID-19, diperlukan pengetahuan dan perilaku pencegahan yang baik di masyarakat. Sebagai calon dokter, mahasiswa kedokteran tingkat akhir perlu memiliki pengetahuan baik agar dapat mengedukasi masyarakat serta perilaku baik agar dapat melindungi diri dan menjadi contoh bagi masyarakat. Tujuan penelitian ini adalah mengetahui tingkat pengetahuan dan perilaku, hubungan pengetahuan dengan perilaku, serta hubungan faktor sosiodemografi dan sumber informasi dengan pengetahuan dan perilaku terhadap COVID-19 pada mahasiswa tingkat akhir FKUI tahun ajaran 2020/2021. Penelitian ini menggunakan desain potong lintang dengan sampel seluruh mahasiswa tingkat akhir FKUI. Instrumen yang digunakan adalah kuesioner Knowledge, Attitude and Practice toward the Novel Coronavirus (COVID-19) yang disebarkan secara daring. Data dianalisis dengan uji chi-square dan uji Fisher. Tingkat pengetahuan subjek yang tergolong sangat baik adalah 70%. Tingkat perilaku subjek mayoritas tergolong cukup yakni 65,5%. Tidak terdapat hubungan antara pengetahuan dengan perilaku (p=0,403), namun terdapat hubungan antara jenis kelamin dan sumber informasi utama dengan pengetahuan (p=0,011 dan 0,005). Pengetahuan mahasiswa kedokteran tingkat akhir mengenai COVID-19 tergolong sangat baik, namun perilaku tergolong cukup. Untuk meningkatkan perilaku, diperlukan intervensi langsung secara struktural dari universitas, tidak hanya dengan peningkatan pengetahuan.
The Role Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome Widhy Yudistira Nalapraya; Menaldi Rasmin; Zuswayudha Sjamsu
Jurnal Respirologi Indonesia Vol 43, No 1 (2023)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v43i1.436

Abstract

Treatment of oxygen therapy should be based on appropriate indication and dose of administration. British Thoracic Society (BTS) recommends oxygen therapy were administered with a 94–98% saturation target in most acute patients and for patients with hypercapnic respiratory failure, BTS recommends 88-92 saturation target or spesific saturation target. Acute respiratory distress syndrome (ARDS) is characterized by acute, diffuse, inflammatory lung injury leading to increased capillary permeability in the alveolus with clinical manifestations of hypoxemia and bilateral opafication. The use of extracorporeal membrane oxygenation (ECMO) along with mechanical ventilator can be useful for ARDS patients and can improve survival.
Gut-Lung Axis Anggie Indari; Menaldi Rasmin; Ari Fahrial Syam
Respiratory Science Vol. 3 No. 2 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v3i2.68

Abstract

Microbiota and the body's immune system have a two-way interaction that is interconnected. The microbiota plays a role in the formation and maturation of the immune system, on the other hand, the immune system shapes the composition and function of the microbiota. This interaction is important in maintaining the body’s immune system’s homeostasis. The human intestine contains various types of microbes that form the gut microbiota. Various studies have found that changes in the gut microbiota are associated with immunity in distal tissues such as the lung. This gives rise to the concept of a feedback relationship between the gut and lung organs called the gut-lung axis. Through this axis, changes in the composition of the gut microbiota not only cause abnormalities in the gut but also affect microbiota in the lungs and can cause disease. One of the important routes in the transmission of substances from the intestine is through the mesenteric lymphatics. Probiotics can help improve the gut’s defense mechanism. A high-fiber diet can also reduce pathogenic bacteria by increasing levels of short-chain fatty acids. Therefore, a healthy lifestyle is needed to maintain the balance of the microbiota.
Co-Authors Adang Bachtiar Agus Dwi Susanto Alatas, Mohammad Fahmi Amien, Bagus Radityo Andre Prawira Putra Anggie Indari Aniwdyaningsih, Wahju Anwar Jusuf Ari Fahrial Syam Arifin Nawas Bies, Asri Liqditta Budhi Antariksa Desianti, Ginanjar Arum Desilia Atikawati Dewi Friska Dian Megawati Diyan Ekawati Elhidsi, Mia Elisna Syahrudin Erlina Burhan Ernita Akmal Faisal Yunus Faisal Yunus Fanny Michelle Filemon Suryawan Handjaja Hadiarto Mangunnegoro Hasibuan, Thariq Emyl Taufik Hilma Nur Faiza Ika Yunita Sari Kartikawati, Falah Kemal Akbar Suryoadji Kevin Aristyo Latona Sidarta, Altama Nani Cahyani Sudarsono Nani Cahyani Sudarsono Neny Husnaini Zain Nina Aspiah Novita Maulidiyah Prasenohadi Prasenohadi Prasenohadi Prasenohadi Prasenohadi, Prasenohadi Pusparini Kusumajati Putri Suci Rahardjo, Tri Apriliawan Bendarto Ratnawati Antaria Reisa, Tina Risa Febriana Rita Rogayah Sakinasha Siva Utami Saroyo, Yudianto Budi Soehardiman, Dicky Sri Indah Indriani Sri Wening Pamungkasningsih Steven Jonathan Taufik, Feni Fitriani Vina Fiqria Wahju Aniwidyaningsih Widhy Yudistira Nalapraya Widjanantie, Siti Chandra Wirya Sastra Amran Wiwien H. Wiyono Zulhadji, Harry Agustio Zuswayudha Sjamsu