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Arsita Eka Rini
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Risk factors contributing to weaning failure from continuous positive airway pressure to high flow nasal cannula in neonates with respiratory distress syndrome Putra, Najih Rama Eka; Dadiyanto, Dwi Wastoro; Sahyuni, Riza; Rini, Arsita Eka; Muryawan, Heru; Suswihardhyono, Adhie Nur Radityo
Paediatrica Indonesiana Vol 64 No 1 (2024): January 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.1.2024.77-85

Abstract

Background Respiratory distress syndrome (RDS) is one of the most frequent causes of mortality and morbidity in neonates. High flow nasal canule (HFNC) is a step ladder modality of alternative oxygen therapy for weaning to reduce the workload of breathing and the need for intubation. Objective To identify the risk factors contributing to weaning failure from continuous positive airway pressure (CPAP) to HFNC in neonates with RDS. Methods This study was a retrospective observational study in neonates aged less than 36 weeks weighing less than 2500 grams who underwent CPAP to HFNC weaning from 2019 to 2021 in Dr. Kariadi Hospital, Semarang, Central Java, Indonesia. Results There were 108 patients included in this study. Our bivariate analysis found significant differences in gestational age, age at the start of weaning, body weight at the start of weaning, FiO2 levels, history of maternal chorioamnionitis, patent ductus arteriosus (PDA), anemia, apnea of prematurity (AOP), and sepsis in neonates with RDS. Multivariate analysis showed that the most dominant factors were FiO2 levels of more than 25% at the start of weaning (OR11.16; 95%CI 1.83 to 63.12; P=0.009), anemia (OR 7.70; 95%CI 1.39 to 42.67; P=0.019), AOP (OR 19.64; 95%CI 4.27 to 90.35; P<0.001), and sepsis (OR 10.93; 95%CI 2.37 to 45.53; P=0.002) Conclusion FiO2 setting of more than 25% at the start of weaning, anemia, AOP, and sepsis produce a significant probability of HFNC weaning failure.
Coronavirus Disease 2019 (COVID-19) Pada Anak (Studi Literatur) Anantyo, Dimas Tri; Kusumaningrum, Ayu Anggraini; Rini, Arsita Eka; Radityo, Adhie Nur; Rahardjani, Kamilah Budhi; Sarosa, Gatot Irawan
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1A (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (395.552 KB) | DOI: 10.36408/mhjcm.v7i1A.479

Abstract

Latar Belakang: Pandemi Novel Coronavirus Disease 2019 (COVID-19) yang disebabkan oleh virus SARS CoV-2 ini berawal dari Wuhan, China, menyebar ke lebih dari 200 negara dan mengakibatkan puluhan ribu kematian termasuk anak. Studi literatur yang membahas COVID-19 pada orang dewasa mulai bermunculan, namun pada anak masih terbatas. Dalam studi literatur ini kami mengulas beberapa artikel ilmiah dan literatur terbaru tentang COVID-19 pada anak yang dipublikasikan sejak Januari 2020 hingga akhir Juli 2020, khususnya manifestasi klinis dan pemeriksaan penunjang. Metode: Mengulas publikasi 35 literatur ilmiah mengenai COVID-19 anak pada jurnal seperti Pubmed, Google Scholar, Science Direct, The Lancet sejak Januari hingga Juli 2020. Hasil: Kejadian COVID-19 pada anak lebih rendah dan memiliki gejala yang lebih ringan dibandingkan orang dewasa. Gejala yang sering muncul adalah batuk, faring hiperemis, dan demam. Belum ada bukti jelas mengenai kejadian transmisi intrauterine yang dilaporkan. Prognosis menunjukkan respon terapi yang baik dan pemulihan yang lebih cepat dibandingkan dengan orang dewasa. Kesimpulan: Kejadian COVID-19 lebih rendah, manifestasi klinis lebih ringan dan prognosis lebih baik pada anak dibandingkan dengan orang dewasa. Kata kunci: COVID-19, anak, studi literatur Background: The Novel Coronavirus Disease 2019 (COVID-19) pandemic caused by the SARS CoV-2 virus originated in Wuhan, China, spread to more than 200 countries and resulted in tens of thousands of deaths including children. Literature studies discussing COVID-19 in adults are starting to emerge, but in children it is still limited. In this literature study, we review some of the latest scientific articles and literature on COVID-19 in children published from January 2020 to the end of July 2020, in particular clinical manifestations and supporting examinations. Methods: Reviewing 35 scientific literatures about children with COVID-19 in journals such as Pubmed, Google Scholar, Science Direct, The Lancet from January to July 2020. Results: The incidence of COVID-19 in children was lower and had milder symptoms than adults. Symptoms that often appear are cough, hyperemic pharynx, and fever. There was unclear proof of intrauterine transmission. The prognosis of children with COVID-19 showed a good response to therapy and faster recovery compared to adults. Conclusion: The incidence of COVID-19 is lower, the clinical manifestations are milder, and the prognosis is better in children compared to adults. Keywords: COVID-19, children, literature study
Karakteristik Bayi Baru Lahir dari Ibu Terkait COVID-19 di RSUP Dr. Kariadi Semarang Radityo, Adhie Nur; Rini, Arsita Eka; Anam, Moh Syarofil; Sarosa, Gatot Irawan
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1A (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (268.32 KB) | DOI: 10.36408/mhjcm.v7i1A.481

Abstract

Latar belakang Kejadian kasus COVID-19 pada bayi belum banyak dilaporkan dan mekanisme penularan terhadap bayi baru lahir masih belum jelas. Tujuan Melaporkan perbedaan karakteristik bayi baru lahir dari ibu terkait COVID-19 di RSUP Dr. Kariadi Semarang Metode Penelitian retrospektif dengan data sekunder catatan medik bayi baru lahir dari ibu terkait COVID-19 di RSUP dr Kariadi Semarang pada periode April-Mei 2020 dengan kelompok pembanding bayi baru lahir dari ibu tidak terkait COVID-19. Kriteria inklusi semua bayi lahir dari ibu terkait COVID-19 dirawat di rumah sakit dan dilakukan pemeriksaan PCR dengan spesimen swab nasofaring. Data yang dikumpulkan adalah usia kehamilan, jenis kelamin, berat lahir, cara persalinan, usia ibu dan jenis minum yang diberikan pada bayi. Dilakukan uji beda menggunakan uji chi square dan shapiro wilk. Analisis data menggunakan program komputer SPSS. Hasil Dari 46 sampel penelitian terdiri dari 23 bayi lahir dari ibu terkait COVID-19 dan 23 bayi lahir dari ibu tidak terkait COVID-19 dilakukan analisis dengan hasil tidak terdapat perbedaan bermakna dari usia kehamilan, berat lahir, cara persalinan dan usia ibu. Pada kelompok bayi lahir terkait COVID-19 mayoritas lahir dengan jenis kelamin perempuan (74%) dan jenis minum yang diberikan sekitar 86% dengan susu formula. Tidak ada bayi yang mendapat ASI eksklusif pada bayi yang lahir dari ibu terkait COVID-19. Semua bayi yang lahir dari ibu terkait COVID-19 didapatkan hasil swab nasofaring negatif dan tidak menunjukkan gejala apapun sampai dengan pulang. Simpulan Tidak didapatkan perbedaan karakteristik usia kehamilan, berat lahir, cara persalinan dan usia ibu. Terdapat perbedaan karakteristik jenis kelamin dan jenis minum yang diberikan pada kedua kelompok penelitian. Keyword: bayi baru lahir, COVID-19 Background The incidence of COVID-19 cases in newborn has not been widely reported and the mechanism of transmission to the newborn is unclear. Objective To report the characteristics of newborns from mothers related to COVID-19 at Kariadi Hospital Semarang. Method Retrospective study with secondary data on medical records of newborns from mothers related to COVID-19 at Kariadi Hospital in the April-May 2020 period with a comparison group of newborns from mothers not related to COVID-19. Criteria for inclusion of all infants born to mothers associated with COVID-19 were hospitalized and PCR examination carried out with nasopharyngeal swab specimens. Data collected were gestational age, sex, birth weight, mode of delivery, maternal age and type of dietary given to the baby. Analysis tests were performed using chi square test and Shapiro Wilk. Data analysis using SPSS computer programs Result Of the 46 study samples consisting of 23 babies born to mothers related to COVID-19 and 23 babies born to mothers not related to COVID-19 were analyzed with the results that there were no significant differences in gestational age, birth weight, mode of delivery and maternal age. In the group of babies born with COVID-19 the majority were born with a female sex (74%) and the type of dietary given was around 86% with formula milk. No baby gets exclusive breastfeeding for babies born to mothers related to COVID-19. All babies born to mothers related to COVID-19 obtained negative nasopharyngeal swab results and did not show any symptoms until discharge. Conclusion There were no differences in the characteristics of gestational age, birth weight, mode of delivery and maternal age. There were differences in the characteristics of the sexes and types of dietary given in the two study groups. Keyword: newborn, COVID-19
Case Report: Pregnancy with Fetal Hydrathorax Putra, Aditya Arya; Wicaksono, Rahmad Rizal Budi; Pramono, M. Besari Adi; Rini, Arsita Eka
Diponegoro International Medical Journal Vol 2, No 2 (2021): December
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v2i2.11060

Abstract

Background: Cases of fetal hydrothorax (FHT) are rare, with an occurrence probability of 1 in every 10,000-15,000 pregnancies. The condition may remain undiagnosed, and the fetus may be aborted, or death may occur soon after birth in outlying hospitals before transfer to a tertiary care center. The incidence rate of FHT is higher in males than females (2:1). One of the most effective methods of diagnosing fetal hydrothorax is sonography. Three forms of currently available treatments are: thoracentesis, thoracoamniotic shunting (TAS), and thoracomaternal cutaneous drainage. Fetal outcomes could be improved by performing the Extrauterine Intrapartum Treatment (EXIT) procedure.Case Presentation: We present two cases of first pregnancy primary FHT. In the first case, a 24-year-old woman was diagnosed with asymptomatic FHT in the 28th week of gestation without any prior history. In the second case, a 22-year-old woman with poor medical history was diagnosed in the 35th week of pregnancy and was experienced difficulty of breathing. Both pregnancies were delivered by cesarean section based on obstetric indications. Thoracentesis was performed on both neonates, and pathological examination of the pleural fluid was conducted. However, they died shortly after birth.Conclusion: The EXIT procedure is still a challenging method. A fetus with FHT is at significant risk of pulmonary hypoplasia and respiratory distress following delivery. Early diagnosis and intervention of FHT are vital to ensure a good prognosis. Approaching multidisciplinary groups, providing supportive diagnostic facilities and financial support is essential in improving fetal outcomes and preventing FHT in subsequent pregnancies.
Co-Authors Adhie Nur Radityo Adhie Nur Radityo Suswihardhyono Anam, Moh Syarofil Anantyo, Dimas Tri Dwi Wastoro Dadiyanto, Dwi Wastoro Gatot Irawan Sarosa, Gatot Irawan Heru Muryawan Kamilah Budhi Rahardjani, Kamilah Budhi Kusumaningrum, Ayu Anggraini M. Besari Adi Pramono, M. Besari Adi Najih Rama Eka Putra Putra, Aditya Arya Sahyuni, Riza Wicaksono, Rahmad Rizal Budi