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All Journal Jurnal Kedokteran Syiah Kuala International Journal of Integrated Health Sciences Althea Medical Journal Dharmakarya : Jurnal Aplikasi Ipteks Untuk Masyarakat Indonesian Journal of Tropical and Infectious Disease Global Medical and Health Communication Jurnal Sistem Kesehatan Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan

Rasmia Rowawi

Department Of Dermato-Venereology Faculty Of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital Bandung

Author-ID : 364793

Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

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Manifestasi Erupsi Alergi Obat Antiretroviral Pada Pasien HIV/AIDS di Klinik Teratai Rsup Dr. Hasan Sadikin Bandung Periode 2005 – 2014 Siska Armeinesya; Rasmia Rowawi; Muhammad Ersyad Hamda
Jurnal Sistem Kesehatan Vol 4, No 1 (2018): Volume 4 Nomor 1 September 2018
Publisher : Universitas Padjadjaran

Kasus human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) telah menjadi masalah kesehatan dunia. High active antiretroviral therapy (HAART) telah menurunkan angka kematian dan kesakitan pada pasien HIV. Pasien HIV memilki risiko tinggi mengalami erupsi alergi obat dibandingkan masyarakat umum. Penelitian ini bertujuan untuk mengindentifikasi manifestasi erupsi alergi obat ARV pada pasien HIV/AIDS periode 2005–2014 di Klinik Teratai RSUP Dr. Hasan Sadikin Bandung. Penelitian ini menggunakan pendekatan cross-sectional. Data dikumpulkan dari rekam medis pasien HIV/AIDS dengan erupsi alergi obat ARV di Klinik Teratai RSUP Dr. Hasan Sadikin Bandung tahun 2005–2014. Dalam penelitian ini didapatkan sebanyak 111 pasien HIV/AIDS mengalami erupsi alergi obat karena ARV. Erupsi alergi obat ARV banyak terjadi pada wanita (55%) dan pada rentang usia 20-29 tahun (55%). Jumlah CD4 pada pasien HIV/AIDS dengan erupsi alergi obat saat pertama kali terdiagnosis HIV terbanyak adalah <200 sel/mm3 (55%). Manifestasi kulit yang paling umum terjadi adalah ruam makulopapular (89,7%). Reaksi erupsi alergi obat umumnya disebabkan oleh nevirapin (82,5%). Dari penelitian ini didapatkan bahwa ruam makulopapular merupakan manifestasi erupsi alergi obat ARV yang paling sering muncul. Obat yang paling banyak ditemukan menyebabkan erupsi alergi obat adalah nevirapin. Kata kunci: erupsi alergi obat, HIV/AIDS, obat ARV

Prevalensi Servisitis Gonore pada Wanita Hamil di Rumah Sakit Khusus Ibu dan Anak Kota Bandung Tahun 2015 Armina Haramaini; Rachmatdinata Rachmatdinata; Rasmia Rowawi
Global Medical & Health Communication (GMHC) Vol 4, No 1 (2016)
Publisher : Universitas Islam Bandung

Gonore adalah infeksi menular seksual (IMS) yang disebabkan oleh Neisseria gonorrhoeae (N. gonorrhoeae). Salah satu manifestasi klinis gonore pada wanita adalah servisitis yang sebagian besar asimtomatik dan bila tidak diterapi servisitis gonore pada wanita hamil dapat menimbulkan komplikasi pada ibu, kehamilan, dan janin. Tujuan penelitian ini mengetahui prevalensi servisitis gonore pada wanita hamil di Rumah Sakit Khusus Ibu dan Anak (RSKIA) Kota Bandung tahun 2015. Penelitian ini merupakan penelitian deskriptif dengan desain potong lintang. Subjek penelitian adalah 100 wanita hamil dengan bahan pemeriksaan adalah apus endoserviks. Diagnosis servisitis gonore ditegakkan jika pada sedian apus gram ditemukan jumlah polimorfonuklear (PMN) >30/lapang pandang besar (lpb) dan diplokokus gram negatif intraseluler, serta hasil PCR N. gonorrhoeae positif. Hasil PCR N. gonorrhoeae pada seluruh subjek penelitian negatif. Namun, 41 orang (41%) subjek penelitian ditemukan jumlah PMN >30/lpb, tanpa diplokokus gram negatif intraseluler, dan didiagnosis servisitis nongonore. Simpulan penelitian ini, yaitu prevalensi servisitis gonore pada wanita hamil di RSKIA Kota Bandung tahun 2015 adalah 0%. Hasil tersebut diduga karena karakteristik sebagian besar subjek penelitian tidak termasuk ke dalam risiko tinggi mengidap IMS. PREVALENCE OF GONORRHEA CERVICITIS IN PREGNANT WOMEN IN SPECIAL HOPISTAL MATERNAL AND CHILD BANDUNG YEAR 2015Gonnorhea is a sexually transmitted infection (STI) that is caused by Neisseria gonorrhoeae. One of the clinical manifestation of gonnorhea in female is cervicitis, that mostly asymptomatic. If it is left untreated, gonnorheal cervicitis in pregnant woman will cause complication to the mother, pregnancy, and fetus. The aim of this study was to know the prevalence of gonnorheal cervicitis in pregnant woman in mother and children hospital (RSKIA) Bandung in year 2015. The study design was cross sectional and descriptive. Subjects were 100 pregnant women, which was taken the sample from endocervical swab. Diagnosis of gonnorheal cervicitis was established if more than 30/high power field (hpf) polymorphonuclear (PMN) and extra or intracellular gram negative diplococcus found from gram staining, also positive PCR result for N. gonorrhoeae. The result of PCR in all subjects were negative. But, there were 41 subjects with PMN more than 30/hpf, with no intra or extra cellular diplococcus found, and those subjects were diagnosed as non gonnorheal cervicitis. Conclusion of this study was that the prevalence of gonorrheal cervicitis of pregnant woman in RSKIA Bandung in year 2015 is 0%. This result was suggested due to the subjects characteristics in this study mostly were not high risk for STI.

Sifilis Laten: Diagnosis dan Pengobatan Rasmia Rowawi
Global Medical & Health Communication (GMHC) Vol 1, No 2 (2013)
Publisher : Universitas Islam Bandung

Sifilis laten merupakan stadium sifilis yang diakibatkan oleh T. pallidum yang masih menetap dalam tubuh, namun tidak menunjukkan gejala dan hanya menunjukkan hasil pemeriksaan serologis yang reaktif. Sifilis laten yang tidak diterapi dapat menetap bertahun-tahun atau seumur hidup dan dapat meningkatkan risiko terinfeksi HIV. Ibu hamil dengan sifilis laten dini akan menyebabkan sekitar 40% bayi yang dilahirkankannya tertular, 20% prematur, 10% lahir mati, dan 4% meninggal pada waktu dilahirkan. Diagnosis sifilis laten dini ditegakkan bila dalam 12 bulan terakhir ditemukan satu atau lebih dari tanda-tanda berikut ini: peningkatan titer VDRL/RPR sebanyak empat kali atau lebih; pada anamnesis didapatkan gejala sifilis primer dan sekunder; riwayat kontak seksual dengan seseorang yang didiagnosis atau diduga menderita sifilis primer atau sifilis sekunder atau sifilis laten dini; serta kontak seksual dengan seseorang dengan tes VDRL atau RPR dan TPHA reaktif. Pengobatan yang direkomendasikan untuk sifilis laten dini adalah benzatin penisilin 2,4 juta UI, IM, dosis tunggal, sedangkan pada sifilis laten lanjut, benzatin penisilin 2,4 juta UI, IM, diberikan 3 kali dengan interval satu minggu. Pemeriksaan tes serologis sifilis nontreponemal (VDRL atau RPR) dilakukan setelah pengobatan 3, 6, 12, dan 24 bulan untuk menilai keberhasilan pengobatan. LATEN SYPHILIS: DIAGNOSIS AND THERAPYLatent syphilis is one of the syphilis stadiums caused by T.pallidum which is asymptomatic however it shows reactive serology. Patient with latent syphilis without treatment will have the disease throughout their whole life and will increase the risk for HIV infection. Pregnant women with latent syphilis will transmit the disease to 40% of the babies, 20% will be premature, 10% will be still born and 4% will die during delivery. The diagnosis of early latent syphilis is established when in the last 12 months one or more of the following signs are found: four times or more increased titers of VDRL or RPR; history of symptoms of primary and secondary syphilis; a history of sexual contact with someone who was diagnosed with syphilis or suspected of having primary, secondary syphilis or early latent syphilis; history of sexual contact with someone who has VDRL or RPR and TPHA reactive tests. The recommended treatment for early syphilis is a single dose of 2.4 million IU benzathine penicillin, IM, whereas for late syphilis, three dosis of 2.4 million IU benzathine penicillin, IM administered with the intervals of one week. Examination of non treponemal syphilis serology tests (VDRL or RPR) should be performed at 3, 6, 12, and 24 months after treatment, to assess the treatment outcome.

Herpes Genitalis dengan Gambaran Klinis Tidak Khas pada Penderita AIDS Keni Istasaputri; Tony S. Djajakusumah; Rachmadinata Rachmadinata; Rasmia Rowawi
Global Medical & Health Communication (GMHC) Vol 1, No 1 (2013)
Publisher : Universitas Islam Bandung

Dilaporkan sebuah kasus herpes genitalis dengan gambaran klinis yang tidak khas pada seorang laki-laki penderita acquired immuno deficiency syndrome (AIDS) berusia 27 tahun. Penderita datang dengan lesi pada pubis, korpus penis, dan skrotum bagian 1/3 atas, berupa ulkus dangkal multipel, dengan bentuk tidak teratur, tidak terdapat indurasi maupun nyeri tekan. Diagnosis kerja pada saat itu adalah ulkus genital nonspesifik yang ditegakkan setelah diagnosis banding berbagai etiologi disingkirkan melalui berbagai pemeriksaan penunjang. Pada bulan ke-6, tampak lesi baru di sekitar ulkus berupa vesikel, erosi, dan ekskoriasi, sehingga diagnosis kerja menjadi herpes genitalis. Pada pemeriksaan serologis ulang didapatkan hasil IgM antivirus herpes simpleks (VHS) (+), dan Ig G anti-VHS-2 (+). Terapi topikal diberikan kompres, sedangkan untuk terapi sistemik diberikan antibiotik yang sesuai dengan hasil tes resistensi. Terapi asiklovir sistemik dengan dosis 5x400 mg/hari diberikan setelah diagnosis kerja menjadi herpes genitalis. ATYPICAL GENITAL HERPES AND NON SPECIFIC CHARACTERISTIC IN AIDS PATIENTA case of genital herpes with atypical clinical feature in a 27-year-old man with AIDS was reported. The patient presented with multiple shallow ulcers in the pubic area, penile shaft, and 1/3 upper scrotum, with irregular shape, without induration, nor pain. The working diagnosis of nonspecific genital ulcer was made after the differential diagnoses of various etiologies were eliminated through further examination. On the sixth month of follow-up, there were new lesions found around the genital ulcers, which were vesicles, erosions, and excoriations, therefore the working diagnosis turned to genital herpes. Result from second serological examination revealed positive anti-HSV2 IgM, and positive anti-HSV2 IgG. Topical treatment consisted of compress and systemic antibiotic was also given based on resistency test result. Then, 400 mg acyclovir 5 times daily was given after the working diagnosis of genital herpes was established.

PREVALENCE OF TRICHOMONIASIS IN ASYMPTOMATIC PREGNANT WOMEN POPULATION IN BANDUNG, WEST JAVA, INDONESIA Achdiat, Pati Aji; Dwiyana, Reiva Farah; Feriza, Vina; Rowawi, Rasmia; Effendi, Rendy Ariezal; Suwarsa, Oki; Gunawan, Hendra
Indonesian Journal of Tropical and Infectious Disease Vol. 7 No. 4 (2019)
Publisher : Institute of Topical Disease Universitas Airlangga

About 81% of pregnant women with trichomoniasis are asymptomatic, while trichomoniasis in pregnant women can increase the risk of complications, include premature rupture of membranes, preterm birth, and babies with low birth weight. Trichomoniasis can also increase the risk of other sexually transmitted infections (STIs) and human immunodeficiency virus (HIV) transmission. Trichomoniasis case in pregnant women could be influenced by demographic characteristics,, the sexual behavior, and also the diagnostic method used. Until now, there is no data about prevalence of trichomoniasis in pregnant women in Indonesia. The aim of this research was to determine the prevalence of trichomoniasis in pregnant women in Bandung, West Java, Indonesia. A descriptive cross-sectional study was performed in December 2016 until January 2017. The study participants were 50 pregnant women who visit antenatal care to Obstetric and Gynecology Clinic of 'Rumah Sakit Khusus Ibu dan Anak Kota Bandung', and meet the inclusion and exclusion criteria, through consecutive sampling. The study participants had a history taking, venereological examination, and Trichomonas rapid test from vaginal swabs. Trichomoniasis in this study was diagnosed based on Trichomonas rapid test, a test that uses color immunochromatographic, capillary flow, dipstick technology, and has high sensitivity and specificity in diagnosing trichomoniasis. Almost all participants in this study were low risk pregnant women to have STI based on demographic characteristics and sexual behaviour. The positive Trichomonas rapid test result was found from one of 50 study participants. In conclusion, prevalence of trichomoniasis in pregnant women in Bandung was 2%. Trichomoniasis case in low-risk pregnant women population is still found.

Chlamydial Infection Prevalence in Human Immunodeficiency Virus Patients Teja, Feilicia Henrica; Rowawi, Rasmia Rowawi; Soedarwoto, Asmaja; Puspitosari, Diah; Rasianti, Rini; Rahmatdinata, Rahmatdinata; Djadjakusumah, Tony
International Journal of Integrated Health Sciences Vol 1, No 1 (2013)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Objective: To determine the prevalence of chlamydial infection in male urethra and female cervix of HIV-positive patients based on PCR assay in Teratai Clinic, Dr. Hasan Sadikin General Hospital Bandung. Methods: A cross sectional observational study with consecutive sampling method, which was conducted in Teratai Clinic during the month of July 2012. All participants underwent history taking, physical examination, and PCR assay for C. trachomatis. Swab samples were obtained from male urethra and female endocervix. Results: Eighty one HIV-positive patients, consisted of 48 males and 33 females were included in this study. The PCR examination for C. trachomatis was positive in 14 of 81 subjects (17.3%), with 10 (20.8%) urethral chlamydial infection in 48 males and four (12.1%) cervical chlamydial infection in 33 females. Conclusions: The study concluded that the prevalence of chlamydial infection in male urethra and female cervix of HIV-positive patients were 20.8% and 12.1%, respectively. Identifying chlamydial infection based on PCR testing should be considered for routine screening test in HIV-positive patients. Keywords: Chlamydia trachomatis, HIV, prevalence, PCR DOI: 10.15850/ijihs.v1n1.107

Co-Authors Aisyah Riseta Aini Hendrana Aisyah Riseta Aini Hendrana, Aisyah Riseta Aini Armeinesya, Siska Armina Haramaini Asmaja Soedarwoto Asmaja Soedarwoto Cahyawari, Dartri Dendi Sandiono Diah Puspitosari Diah Puspitosari Dina Fatmasari Effendi, Rendy Ariezal Febrina, Dia Feilicia Henrica Teja Feilicia Henrica Teja Feriza, Vina Gynaecia Lamsu Hamda, Muhammad Ersyad Hartati Dharmadji Jayawarsa, A.A. Ketut Keni Istasaputri Keni Istasaputri, Keni Kuswandewi Mutyara Muhammad Ersyad Hamda Oki Suwarsa Pati Aji Achdiat Rachmadinata Rachmadinata Rachmadinata Rachmadinata, Rachmadinata Rachmatdinata Rachmatdinata Rahmatdinata Rahmatdinata Rahmatdinata Rahmatdinata Reiva Farah Dwiyana Reyshiani Johan Rini Rasianti Rini Rasianti Risa Miliawati Roslina, Nina Siska Armeinesya Tony Djadjakusumah Tony Djajakusumah Tony S Djajakusumah, Tony S Tony S. Djajakusumah

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