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All Journal VALENSI JURNAL KIMIA SAINS DAN APLIKASI Jurnal Natur Indonesia Jurnal Sains Materi Indonesia Bulletin of Chemical Reaction Engineering & Catalysis The Journal of Pure and Applied Chemistry Research Jurnal Farmasi Andalas Jurnal Riset Kimia Jurnal Kimia dan Kemasan Elkawnie Jurnal Litbang Industri Lantanida Journal Indonesian Journal of Chemistry Jurnal Ecolab Molekul: Jurnal Ilmiah Kimia Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Hydrogen: Jurnal Kependidikan Kimia REACTOR : Journal of Research On Chemistry And Engineering Jurnal Kimia dan Kemasan Jurnal Litbang Industri Bulletin of Chemical Reaction Engineering & Catalysis al Kimiya : Jurnal Ilmu Kimia dan Terapan Jurnal Akademika Kimia
Safni Safni
Department Of Chemistry, Faculty Of Mathematics And Natural Sciences, Andalas University, Kampus Unand Limau Manis Padang, 25163
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Energy Engineering Environmental Science Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Social Sciences Other

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Journal : Jurnal Farmasi Andalas

 1 
Uji Stabilitas Kimia Natrium Askorbil Fosfat Dalam Mikroemulsi Dan Analisisnya Dengan HPLC Deviarny, Chris; Lucida, Henny; Safni, Safni
Jurnal Farmasi Andalas Vol 1, No 1 (2013)
Publisher : Jurnal Farmasi Andalas

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Abstract

It has been tested the influence of pH, the influence of microemulsion types and the influence of storage temperature on the stability of natrii ascorbyl phosphate (which is often known as Sodium Ascorbyl Phosphate/SAP) and analysis using HPLC method. Kinetics test carried out by dissolving the SAP in a buffer solution with different pH, namely: 4.5: 5.5: 6.5 and 7.5 at a temperature of 300C and 400C. SAP decomposes according to first-order kinetics (y = -0.0027 x - 3.5224 and r = 0.9546, price the value of k = 6.2181 x 10-3 per minute) with a slow rate of decomposition at pH 6.5. Furthermore, SAP isformulated in the preparation of microemulsion type of M/A and A/M with anoptimum pH conditions for SAP, then tested the stability of SAP with SAP store at  temperatures 300C and 400C for one week. The remaining levels of SAP werecalculated and analyzed by one-way T-tested method. Showed that the type of chemical stability of microemulsions affect SAP which is morestable in the microemulsion type of M/A.   
Co-Authors -, Maizatisna -, Roswita -, Zulfarman Abinul Hakim Adlis Santoni Admi Admi Aldini, Tasya Amelia, Fitrah Anggraini, Deby Anna Fadhilla Arief Yandra Putra Bhayu Gita Bhernama BUSTANUL ARIFIN Chris Deviarny Deby Anggraini Deliza - Deliza, Deliza Desmiati - Deswati Deswati Dheasy Gustira Dina Nofebriani Dini Hariyati Adam Donanita, Tysa Dytta Fitria Elma Fadrita Rahman Emriadi - Eno Okta Patricia Era, Yuni Fadhilla, Anna Fardila Sari Febi Rahmi Febrina Arfi Fitra Febrianti Fitrah Amelia Fitrah Amelia fitri mairizki Fitri Mairizki, Fitri Fivi Mona Bareno Gustiana, Mega Hakim, Abinul Hamzar Suryani Hamzar Suyani Harza Dipajana Umardi Hazanita Jumiaty Hazanita Jumiaty Henny Lucida Hermansyah Aziz Hermansyah Aziz Hilfi Pardi Ibnu Irawan Imelda Imelda Jarnuzi Gunlazuardi Jihanul Khaira K Khoiriah Khoiriah Khoiriah Khoiriah Khoiriah Khoiriah Khoiriah Khoiriah Khoiriah Khoiriah Khoiriah Khoiriah Khoiriah, Khoiriah Liansari, Oktanora Mai Efdi Mai Efdi Maizatisna - Maizatisna Maizatisna Marniati Salim Matlal Fajri Alif Mechy Rezita Wahyuni Mega Gustiana Muhamad Nasir Muhamad Nasir, Muhamad Neila Yenni Norman Ferdinal Novesar Jamarun Novesar Jamarun Nurul Pratiwi Oktanora Liansari Olly Norita Tetra Putri Arwanda Putri Perdana Roza Putri, Reza Audina Rahmi, Febi Rahmiana Zein Refilda Refilda Refinel - Reza Audina Putri Reza Audina Putri Roswita - Roza, Putri Perdana Sakai, T. Sakai, Tadao Salmariza Sy Sumaryati Syukur Suryati , Suryati Suryati Suryati Syukri - Syukri Arief Syukri Syukri Syukri Syukri Syukri Syukri T. Sakai Tadao Sakai Tommi Hermansyah Trisna Olinovela Trisna Ollinovela Umiati Loekman Umiati Loekman Umiati Loekman Upita Septiani Vanny Yulia Safitri Vepilia Wulanda Wellia, Diana Vanda Willy Cahya Nugraha Willy Cahya Nugraha, Willy Cahya Yefrida - Yefrida Yefrida Yetria Rilda Yuli Okta Fitriyani Yulizar Yusuf Yulizar Yusuf Yuni Era Zaimi Abdullah Zaimi Abdullah Zilfa Zilfa Zulfarman - Zulfarman Zulfarman Zulkarnain Chaidir