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Pengaruh Pemberian Ekstrak Etanol dan Ekstrak n-Heksan Daun Ketepeng Cina (Cassia Alata. L) terhadap Waktu Kematian Cacing Pita Ayam (Raillietina Sp.) Secara In Vitro Intannia, Difa; Amelia, Rezki; Handayani, Lisda; Santoso, Heri Budi
JURNAL PHARMASCIENCE Vol 2, No 2 (2015): JURNAL PHARMASCIENCE
Publisher : JURNAL PHARMASCIENCE

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ABSTRAK            Indonesia diketahui banyak memiliki tumbuhan yang berkhasiat obat, diantaranya adalah daun ketepeng cina (Cassia alata. L) yang mempunyai khasiat sebagai obat cacing, sariawan, sembelit, panu, kurap, kudis dan gatal-gatal. Tujuan Penelitian: untuk mengetahui pengaruh pemberian ekstrak etanol dan n-heksan daun ketepeng cina (Cassia alata. L) terhadap waktu kematian cacing pita ayam secara in vitro. Metode Penelitian: Merupakan penelitian eksperimental dengan memberikan perlakuan terhadap cacing pita ayam yang direndam dalam ekstrak etanol dan ekstrak n-heksan dengan dosis 25 mg/25 mL, 50 mg/25 mL, 75 mg/ 25mL dan 100 mg/25 mL serta sebagai pembanding adalah mebendazole dengan seri dosis yang sama. Setiap perlakuan dilakukan 3 kali replikasi dengan masing-masing replikasi menggunakan 5 ekor cacing. Waktu kematian cacing dicatat dan dilakukan analisis. Hasil Penelitian: Ekstrak n-heksan diketahui lebih cepat mematikan cacing pita ayam dibandingkan dengan ekstrak etanol, namun masih lebih lambat dibandingkan dengan mebendazole. Dosis  100 mg/ 25mL memberikan waktu kematian yang paling cepat pada semua kelompok, dengan waktu kematian sebagai berikut: 1) Ekstrak etanol 202 menit±17.48, 2) Ekstrak n-heksan 138 menit±26,94 dan Mebendazole 95 menit±21,68. Kesimpulan: Ekstrak etanol dan n-heksan mampu mematikan cacing pita ayam (Raillietina sp.) secara in vitro.Kata kunci: Efek anthelmintic, daun Cassia alata. L, ekstrak etanol, ekstrak n-heksan, Raillietina spAbstractKetepeng Cina (Cassia alata. L) is one of Indonesian medical herb which have properties as an anthelmintic, laxative, treat scabies and itchy. Aim of this study is to understand the effect of ethanolic and n-hexane leaf extract of Cassia alata. L toward mortality time of chicken tapeworm (raillietina sp.) in vitro. Four concentrations (25, 50, 75 and 100 mg/ 25 mL) of each extract were studied in activity, which involved the determination time of death of the tapeworm. Both the extracts exhibited best anthelmintic effect at highest concentration of 100 mg/25 ml.  Mebendazole  in  same  concentration  as  that  of  extract  was included  as  standard  reference. Mortality time for each extracts are 1) Ethanolic extracts 202 minute±17.48; 2) n-hexane extract 138 minute±26.94 and Mebendazole 95 minute±21.68  The ethanolic  and  n-hexane leaf  extracts of Cassia alata. L has effect toward mortality time of chicken tapeworm Raillietina sp. in vitro.Key word: Anthelmintic effect, Cassia alata. L, Ethanolic leaf extract, n-Hexane leaf extract, Raillietina sp
Profil SGPT dan SGOT Ikan Nila (Oreochromis niloticus L.) di Sungai Riam Kanan Kalimantan Selatan Hidayaturrahmah, Hidayaturrahmah; Muhamat, Muhamat; Santoso, Heri Budi
JURNAL PHARMASCIENCE Vol 2, No 2 (2015): JURNAL PHARMASCIENCE
Publisher : JURNAL PHARMASCIENCE

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ABSTRAK Penelitian ini dilakukan untuk mengetahui  Profil nilai SGPT dan SGOT ikan nila pada budidaya keramba di sungai riam kanan sebagai parameter untuk mengetahui fisiologi pada organ hati. Penentuan kadar SGPT dan SGOT dengan metode spektrofotometri (UV Visible spectrometer, GBC Scientific Equipment). Sampel ikan Nila (Oreochromis niloticus L.) diambil dari tiga titik stasiun di sekitar sungai Riam Kanan, kemudian dari tiap stasiun dilakukan 3 kali pengambilan sampel. Hasil penelitian menunjukkan bahwa pada fungsi hati ikan nila pada stasiun I (Desa Awang Bangkal), Stasiun II (Desa Mandikapau) dan stasiun III (Desa Sungai alang) menghasilkan nilai SGPT dan SGOT yang lebih tinggi apabila dibandingkan dengan nilai normal SGPT dan SGOT ikan nila tawar pada umumnya. Profil  SGPT dan SGOT paling tinggi terdapat pada stasiun Mandikapau yaitu sebesar 75 ± 21 U/I dan 204,67 ± 56,72. Profil nilai SGPT/SGOT paling rendah terdapat pada stasiun  awang Bangkal  sebesar 45 ± 18,73U/I dan 139,67 ± 26,84. Penelitian ini menunjukkan bahwa secara fisiologis profil SGPT dan SGOT  Ikan Nila di perairan sungai Riam dinilai terdapat adanya gangguan pada hati. Hal ini dapat dilihat dari nilai SGPT dan SGOT yang  lebih rendah dari nilai normal.Kata kunci : SGPT, SGOT, Ikan Nila, Sungai Riam Kanan ABSTRACTThis study was conducted to determine the value of SGPT and SGOT profile tilapia in aquaculture cages in the river rapids as the right to determine the physiological parameters in the liver. Determination of SGPT and SGOT levels by spectrophotometric method (UV-Visible spectrometer, GBC Scientific Equipment). Samples Nile Tilapia (Oreochromis niloticus L.) were taken from the three-point stations around the river Riam Kanan, then from each station sampling is done 3 times. The results showed that the liver function of tilapia at station I (Desa Awang Bangkal), Station II (Village Mandikapau) and the station III (Sungai grasslands) produce value SGPT and SGOT were higher when compared with normal values SGPT and SGOT tilapia bargaining in general. SGPT and SGOT profile is highest in Mandikapau station that is equal to 75 ± 21 U / I and 204.67 ± 56.72. Profile value SGPT / SGOT lowest contained in Bangkal awang station by 45 ± 18.73U / I and 139.67 ± 26.84. This study shows that physiological profile SGPT and SGOT Tilapia in river waters cascade assessed there is a disturbance in the heart. It can be seen from SGPT and SGOT values were lower than normal value.Keywords: SGPT, SGOT, Oreochromis niloticus L.
THE POTENTIAL OF KALANGKALA (Litsea angulata) SEED EXTRACT AS A NATURAL SPERMICIDE MATERIAL Akmal, Rommy; Rusmiati, Rusmiati; Santoso, Heri Budi
TROPICAL WETLAND JOURNAL Vol 3, No 2 (2017)
Publisher : The Journal is published by Graduate Programe of Lambung Mangkurat University

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Kalangkala (Litsea angulata) is one of the endemic plants in the wetlands area inKalimantan which seeds are can reduce the quality of male mice spermatozoa such as motility and mobility. The purpose of this research is to know the potential of kalangkala seed extract on other parameters of spermatozoa quality, which are viability and morphology of male mice spermatozoa in an effort to obtain natural spermicide material. This research used five treatments by using twentyfive male mice. The design of this research was spermatozoa suspensions without being treated (Control = 0), spermatozoa suspensions +Na-CMC 0,5% (P1), spermatozoa suspensions + extract of kalangkala seed 0,1% (P2), spermatozoa suspensions + extract of kalangkala seed 0,3% (P3), and spermatozoa suspensions + extract of kalangkala seed 0,5% (P4), with five repititions for each treatment. The result of this research showed that thekalangkala seed extract reduce the percentage of viability of spermatozoa and increased the percentage of abnormal morphology of spermatozoa male mice. Therefore, kalangkala seed extract has potential as a natural spermicide.
Study Implementation of Link and Match Teacher Expert from Dudika at Vocational Schools in Blitar Regency Santoso, Heri Budi; Marsono, Marsono; Widiyanti, Widiyanti
Budapest International Research and Critics Institute-Journal (BIRCI-Journal) Vol 4, No 4 (2021): Budapest International Research and Critics Institute November
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v4i4.3136

Abstract

Vocational High School is an educational institution whose role is to prepare students to become middle-level workers to build the nation's economic sector. In the implementation of education, Vocational High Schools have the authority to determine their own curriculum to be used based on Dudika's needs. As an effort to fulfill these needs, SMK cooperates with Dudika through the implementation of expert teachers. This research is a multi-case study that describes and compares the implementation of Link and Match Guru Expert from PT Medion Ardhika Bhakti at SMK Negeri I Kademangan and SMK Negeri | Udanawu. This study aims to describe the process of planning, implementation, preparation, form of MoU, evaluation and impact of the implementation of expert teachers. Data collection techniques were carried out through interviews, observations and field notes on the activities of expert teachers.
Iron bioaccumulation and ecological implications in the coastal swamp wetlands ecosystem of South Kalimantan: Insights from giant mudskipper fish as bioindicators Santoso, Heri Budi; Krisdianto, Krisdianto; Yunita, Rizmi
Journal of Degraded and Mining Lands Management Vol. 11 No. 3 (2024)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15243/jdmlm.2024.113.5539

Abstract

This study investigated iron (Fe) accumulation in South Kalimantan's coastal swamp wetlands ecosystem, utilizing giant mudskipper fish as indicators of heavy metal pollution. By analyzing Fe levels in water, sediment, and fish organs over time, insights into its effects on the environment and human health were gained. Furthermore, through Atomic Absorption Spectrometry, Fe concentrations in Kuala Lupak's coastal wetland were measured, revealing significant correlations between Fe levels in water, sediment, and fish tissues. These results enhance our understanding and inform better management strategies. Anthropogenic and natural sources contribute to the accumulation of heavy metals, particularly Fe, with anthropogenic pollution being the most dominant. This study presented the escalating concentrations of Fe within the Kuala Lupak estuary and raised concerns regarding the ecological and human health implications. Continuous monitoring, source identification, public awareness, regulations, remediation, and long-term exploration are essential for addressing heavy metal pollution and its ecological impact. Therefore, valuable insights are provided for environmental management and conservation efforts.
Assessing Pb and Cd levels in the water of Kapuas River of Central Kalimantan using water hyacinth as a biomonitor plant Olfa, Maria; Santoso, Heri Budi; Rakmawati, Rakmawati; Mintowati, Evi Kuntorini
Journal of Degraded and Mining Lands Management Vol. 12 No. 5 (2025)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15243/jdmlm.2025.125.8525

Abstract

This study evaluated heavy metal pollution in the Kapuas River, Central Kalimantan, with a focus on lead (Pb) and cadmium (Cd). This study focused on the Kapuas River due to the high anthropogenic activities that cause pollution and the lack of previous biomonitoring studies. Water and water hyacinth (Eichhornia crassipes) samples were collected from four locations in Kapuas Regency between March and April 2023 using a purposive sampling method. This study aimed to evaluate the levels of Pb and Cd in water bodies and the roots of water hyacinth in the Kapuas River. The results showed that the Pb concentration in river water averaged 0.00184-0.00451 mg/L, and Cd in river water averaged 0.00182-0.02595 mg/L, indicating that the river water has been contaminated with Pb and Cd but still within the quality standard. The Pb concentration in water hyacinth roots averaged 4.98-7.33 mg/kg, while the Cd concentration was <0.001 mg/kg. The pollution index of the Kapuas River ranged from 2.29 to 3.08, classified as lightly polluted. The correlation between Pb in the roots of water hyacinth and the water was between -0.60 and -0.89, indicating that the lower the Pb in the water, the higher the Pb in the roots of water hyacinth. Therefore, water hyacinth has the potential to be a bioindicator of Pb pollution.
Assessment of Lead (Pb) Bioaccumulation in Seluang Fish (Rasbora sp.) and Water Quality Analysis in Miai Riverysis of Lead (Pb) levels in Seluang Fish (Rasbora Sp) in the Miai River in Banjarmasin City Azzahra, Yenni; Santoso, Heri Budi; Muhamat, Muhamat
Jurnal Biologi Tropis Vol. 25 No. 1 (2025): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i1.8553

Abstract

The waters of the Miai River are located in a densely populated residential area with a variety of household activities and landfills (TPS), one of which is hazardous waste containing heavy metals. Heavy metal lead (Pb) is dangerous because it is toxic. The study's objectives were to quantify the lead concentration in seluang fish and water and ascertain the correlation between fish weight and lead levels in water. The Miai River's waters served as the site of the study. Purposive sampling was used to collect water and seluang fish samples. The Pb concentration was determined using an Atomic Absorption Spectrophotometer (AAS) after samples were collected from two stations three times. The results of Pb content in river water at station 1 averaged around 0.00589 mg/L and station 2 averaged around 0.00690 mg/L and the results of Pb levels in seluang fish at station 1 averaged around 0.00333 mg/kg and station 2 averaged around 0.00600 mg/kg. This means that river water and seluang fish are contaminated with Pb but still below the quality standards set, so they can still be utilized according to their designation and are still safe for consumption. The relationship between Pb in fish and fish weight shows a correlation coefficient of r = -0.598, meaning that the correlation is unidirectional and Pb in water with Pb in fish correlates r = 0.439, indicating a relationship with a moderate level.