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All Journal Biospecies JURNAL PHARMASCIENCE Pharmascience Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Narra J Borneo Journal of Pharmacy
Hidayaturrahmah Hidayaturrahmah
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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Profil SGPT dan SGOT Ikan Nila (Oreochromis niloticus L.) di Sungai Riam Kanan Kalimantan Selatan Hidayaturrahmah, Hidayaturrahmah; Muhamat, Muhamat; Santoso, Heri Budi
JURNAL PHARMASCIENCE Vol 2, No 2 (2015): JURNAL PHARMASCIENCE
Publisher : JURNAL PHARMASCIENCE

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Abstract

ABSTRAK Penelitian ini dilakukan untuk mengetahui  Profil nilai SGPT dan SGOT ikan nila pada budidaya keramba di sungai riam kanan sebagai parameter untuk mengetahui fisiologi pada organ hati. Penentuan kadar SGPT dan SGOT dengan metode spektrofotometri (UV Visible spectrometer, GBC Scientific Equipment). Sampel ikan Nila (Oreochromis niloticus L.) diambil dari tiga titik stasiun di sekitar sungai Riam Kanan, kemudian dari tiap stasiun dilakukan 3 kali pengambilan sampel. Hasil penelitian menunjukkan bahwa pada fungsi hati ikan nila pada stasiun I (Desa Awang Bangkal), Stasiun II (Desa Mandikapau) dan stasiun III (Desa Sungai alang) menghasilkan nilai SGPT dan SGOT yang lebih tinggi apabila dibandingkan dengan nilai normal SGPT dan SGOT ikan nila tawar pada umumnya. Profil  SGPT dan SGOT paling tinggi terdapat pada stasiun Mandikapau yaitu sebesar 75 ± 21 U/I dan 204,67 ± 56,72. Profil nilai SGPT/SGOT paling rendah terdapat pada stasiun  awang Bangkal  sebesar 45 ± 18,73U/I dan 139,67 ± 26,84. Penelitian ini menunjukkan bahwa secara fisiologis profil SGPT dan SGOT  Ikan Nila di perairan sungai Riam dinilai terdapat adanya gangguan pada hati. Hal ini dapat dilihat dari nilai SGPT dan SGOT yang  lebih rendah dari nilai normal.Kata kunci : SGPT, SGOT, Ikan Nila, Sungai Riam Kanan ABSTRACTThis study was conducted to determine the value of SGPT and SGOT profile tilapia in aquaculture cages in the river rapids as the right to determine the physiological parameters in the liver. Determination of SGPT and SGOT levels by spectrophotometric method (UV-Visible spectrometer, GBC Scientific Equipment). Samples Nile Tilapia (Oreochromis niloticus L.) were taken from the three-point stations around the river Riam Kanan, then from each station sampling is done 3 times. The results showed that the liver function of tilapia at station I (Desa Awang Bangkal), Station II (Village Mandikapau) and the station III (Sungai grasslands) produce value SGPT and SGOT were higher when compared with normal values SGPT and SGOT tilapia bargaining in general. SGPT and SGOT profile is highest in Mandikapau station that is equal to 75 ± 21 U / I and 204.67 ± 56.72. Profile value SGPT / SGOT lowest contained in Bangkal awang station by 45 ± 18.73U / I and 139.67 ± 26.84. This study shows that physiological profile SGPT and SGOT Tilapia in river waters cascade assessed there is a disturbance in the heart. It can be seen from SGPT and SGOT values were lower than normal value.Keywords: SGPT, SGOT, Oreochromis niloticus L.
PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN GAHARU (Aquilaria microcarpa Baill.) TERHADAP WAKTU PERDARAHAN PADA TIKUS PUTIH JANTAN GALUR WISTAR Cahaya, Noor; Fauzi, Rakhmat; Hidayaturrahmah, Hidayaturrahmah
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 2, No 2 (2017)
Publisher : Akademi Farmasi ISFI Banjarmasin

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Abstract

Daun gaharu (Aquilaria microcarpa Baill.) memiliki kandungan senyawa flavonoid dan tanin yang berpotensi sebagai penyembuhan luka. Penelitian ini bertujuan untuk membuktikan pengaruh pemberian ekstrak etanol daun A. microcarpa terhadap waktu perdarahan tikus putih jantan yang diinduksi heparin. Dua puluh tikus jantan dibagi menjadi 5 kelompok. Kelompok I (kontrol negatif), II (kontrol positif), III, IV dan V  (ekstrak etanol daun A. microcarpa dosis 75mg/KgBB, 100mg/KgBB dan 150mg/KgBB). Hewan uji diberi injeksi heparin selama 5 hari, kemudian diberi sediaan selama 6 hari dicatat waktu tiap 2 hari. Hasil penelitian menunjukkan persentase penurunan waktu perdarahan yaitu 41.74%; 74.74%; 52.09%; 95.86%; 24.36. Hasil statistik menunjukkan perbedaan nyata penurunan waktu perdarahan oleh karena itu dapat disimpulkan bahwa ekstrak etanol daun A. microcarpa berpengaruh terhadap waktu perdarahan pada tikus putih jantan yang diinduksi heparin.
Penampakan Morphologi Kulit Luar Marmut Terhadap Pemberian Minyak Atsiri Tanaman Zodia Secara Rutin Muhamat Muhamat; Hidayaturrahmah Hidayaturrahmah
Biospecies Vol. 7 No. 2 (2014): Juli 2014
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/biospecies.v7i2.1736

Abstract

Minyak atsiri zodia merupakan salah satu minyak atsiri yang mempunyai daya penolak dari aktivitas nyamuk menghisap darah.  Minyak tersebut dapat dikembangkan menjadi bahan pelindung tubuh maka perlu dilakukan penelitian tentang keamanan bahan ini terhadap manusia (pemakai). Karena pemakaian berhubungan langsung dengan permukaan kulit maka penelitian ini difokuskan pada pengamatan terhadap penampakan morfologi kulit akibat pemaparan minyak atsiri zodia.  Pengujian dilakukan denga uji iritasi primer menggunakan metode Draize dengan cara mengolesi minyak atsiri konsentrasi 5% ke kulit marmut. Pengamatan dilakukan setiap hari meliputi pengamatan morfologi  kulit marmut secara makrokospis (eritema dan edema), perubahan warna kulit serta kehalusan kulit.  Pengamatan juga dilakukan terhadap  perubahan tingkah laku selama penelitian.  Hasil pengamatan terhadap semua sampel kulit marmut yang  diolesi minyak atsiri zodia  tidak menunjukkan adanya tanda-tanda kerusakan kulit baik eritema maupun edema.  Kulit yang diolesi minyak atsiri menunjukkan tekstur kulit yang lembut, mengkilat dan licin, yang berbeda dari kulit yang tidak diolesi minyak atsiri. Pengamatan perilaku marmut tidak menunjukkan adanya perilaku keracunan seperti tidak punya nafsu makan, muntah-muntah, diam atau agresif.  Kesimpulan yang dapat diambil dalam penelitian ini adalah minyak atsiri zodia dengan konsentrasi 5% tidak menyebabkan inflamasi pada kulit marmot, bahkan kulit marmut menjadi lebih lembut dan halus.
Analisis Glukosa Ikan Gelodok (Periopthalmodon schlosseri) di Perairan Desa Tanipah dan Desa Kuala Lupak, Barito Kuala Kalimantan Selatan Dewita Rinowati; Hidayaturrahmah Hidayaturrahmah
Jurnal Pharmascience Vol 8, No 1 (2021): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v8i1.8468

Abstract

Sumber energi dan biomarker terhadap kondisi fisiologis ikan dipengaruhi oleh faktor kadar glukosa darah. Penelitian ini bertujuan untuk mengetahui profil glukosa pada ikan gelodok (Periopthalmodon schlosseri) di Desa Tanipah dan Desa Kuala Lupak, Kabupaten Barito Kuala sebagai sumber pengetahuan. Metode yang digunakan adalah  GOD-PAP yaitu penetapan glukosa darah dari sampel serum dan plasma secara enzimatik menggunakan Glukosa Oksidase Para Amino Phenazone menghasilkan warna merah yang diukur dengan fotometer. Hasil yang didapatkan kadar glukosa rata-rata ikan gelodok dari pengambilan Desa Tanipah didapatkan 45,87 ± 13,6 mg/dL Pengambilan di Desa Kuala Lupak rata-rata kadar glukosa sebesar 49,75 ± 27,6 mg/dL. Glukosa ikan gelodok yang didapatkan dari kedua desa tersebut berada dibatas normal kadar glukosa darah pada ikan. Kata Kunci: Glukosa, darah, ikan gelodok, GOD-PAP, glikogen  Energy sources and biomarkers of fish physiological conditions are influenced by blood glucose levels. This study aimed to determine the glucose profile of the jellyfish (Periopthalmodon schlosseri) in Tanipah Village and Kuala Lupak Village, Barito Kuala Regency as a source of knowledge. The method used is GOD-PAP namely the determination of blood glucose from serum and plasma samples enzymatically using Glucose Oxidase The Amino Phenazone produces a red color as measured by a photometer. The results obtained by the average level of glucose in Mudskipper from the taking of Tanipah Village were 45.87 ± 13.6. Taking in the village of Kuala Lupak the average glucose level was 49.75 ± 27.6 mg / dL. Mudskipper fish glucose obtained from the two villages is within the normal limits of blood glucose levels in fish.
Profil Darah Ikan Gelodok (Periophthalmodon schlosseri) dan (Boleophthalamus boddarti) di Desa Kuala Tambangan Pelaihari, Kalimantan Selatan Nita Azhari; Hidayaturrahmah Hidayaturrahmah
Jurnal Pharmascience Vol 7, No 2 (2020): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v7i2.8465

Abstract

Profil darah memiliki peran yang sangat penting dalam fisiologi metabolisme dan aktifitas tubuh hewan. Kuala Tambangan memiliki banyak potensi sumber daya ikan salah satunya ikan gelodok. Ikan gelodok di kawasan ini mudah ditemukan, akan tetapi sampai sekarang belum dimanfaatkan dengan baik oleh masyarakat. Tujuan penelitian ini untuk mengetahui profil darah ikan gelodok jenis Periophthalmodon schlosseri dan Boleophthalamus boddarti pada ekosistem mangrove yang berada di desa Kuala Tambangan, Kabupaten Tanah Laut, Kalimantan Selatan. Metode yang digunakan pada penelitian ini yaitu metode penangkapan hewan langka yaitu line transek, metode hemositometer dan metode sahli parameter yang dihitung hemoglobin, eritrosit, leukosit, hematokrit, MCV (Mean Corpusculla Volume), MCH (Mean Cell Hemoglobin), MCHC (Mean Cell Hemoglobin Concentration) pada 2 jenis ikan gelodok 34 ekor P. schlosseri dan 34 ekor B. boddarti. Hasil yang didapatkan adalah eritrosit P. schlosseri 3,87±0,58 x 106 sel/μL; B. boddarti 3,78±0,73 x 106 sel/μL 2 jenis ikan gelodok ini memiliki nilai eritrosit diatas batas normal; leukosit P. schlosseri 11,91±5,61 x103 sel/μL dan B. boddartii 9,72±4,24 x103 sel/μL nilai leukosit pada 2 jenis ikan gelodok ini berada di atas batas normal; hemoglobin P. schlosseri 11,59±1,75 % dan B. boddartii 11,75±1,96 % dari hasil yang didapat kadar hemoglobin pada 2 jenis ikan gelodok ini berada di atas batas normal kadar hemoglobin ikan pada umumnya; hematokrit P. schlosseri 34,32±5,57 % dan B. boddartii 35,71±5,44 % hasil hematokrit yang didapat dari 2 jenis ikan gelodok ini yaitu di atas batas normal; jenis P. schlosseri memiliki nilai MCV 88,72±6,62 μm3 yang berada di bawah batas normal; MCH 29,92±0,69 pg/sel yang berada di bawah batas normal; MCHC 33,99±3,97 g/dL pada jenis ini nilai MCHC masih berada pada batas normal; jenis B. boddartii memiliki nilai MCV 96,16±17,96 μm3 yang berada di bawah batas normal; MCH 31,51±5,50 pg/sel yang masih berada di batas normal; MCHC 32,87±1,77 g/dL nilai MCHC pada jenis ini masih berada pada batas normal. Blood profile has a very important role in the physiology of metabolism and animal body activities. Kuala Tambangan has a lot of potential fish resources, one of which is the fish Mudskipper. Mudskipper fish in this area are easy to find, but until now it has not been utilized properly by the community. The purpose of this study was to determine the blood profile of the Periophthalmodon Schlosseri and Boleophthalamus boddarti fish species in the mangrove ecosystem in the village of Kuala Tambangan, Tanah Laut District, South Kalimantan . The method used in this study is the method of catching endangered animals namely trasnek line, hemocytometer method and parameter Sahli method which is calculated hemoglobin, erythrocytes, leukocytes, hematocrit, MCV (Mean Corpuscular Volume), MCH (Mean Cell Hemoglobin), MCHC (Mean Cell Hemoglobin Concentration) on 2 types of fish, 34 Periophthalmodon schlosseri and 34 Boleophthalmus boddarti. The results obtained were P. schlosseri erythrocytes 3.87 ± 0.58 x 106 cells / μL; B. boddarti 3.78 ± 0.73 x 106 cells / μL 2 types of fish Mudskipper has erythrocyte values above the normal limit; P. schlosseri leukocytes 11.91 ± 5.61 x103 cells / μL and B. boddartii 9.72 ± 4.24 x103 cells / μL leukocyte values in these 2 types of jagged fish are above normal limits; hemoglobin P. schlosseri 11.59 ± 1.75 % and B. boddartii 11.75 ± 1.96 % from the results obtained by the hemoglobin levels in these 2 types of fishes are above the normal limit of fish hemoglobin levels in general; hematocrit P.schlosseri 34.32 ± 5.57 % and B. boddartii 35.71 ± 5.44 % hematocrit results obtained from these 2 types of mudskipper fish are above normal limits; P.schlosseri species had MCV values of 88.72 ± 6.62 μm3 which were below normal limits; MCH 29.92 ± 0.69 pg / cell that is below the normal range; MCHC 33.99 ± 3.97 g / dL in this type the MCHC value is still in the normal range; type B. boddartii has a MCV value of 96.16 ± 17.96 μm3 which is below normal limits; MCH 31,51 ± 5.50 pg / cell which is still in the normal range; MCHC 32.87 ± 1.77 g / dL MCHC values in this type are still within normal limits.Keywords: gelodok, blood, kuala tambangan
Analisis Profil Lipid Ikan Gelodok (Periophthalmodon schlosseri) di Desa Tanipah dan Desa Kuala Lupak Kalimantan Selatan Gusti Maharani; Hidayaturrahmah Hidayaturrahmah
Jurnal Pharmascience Vol 7, No 2 (2020): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v7i2.8458

Abstract

Lipid adalah kelompok molekul alami yang berperan penting sebagai bahan bakar metabolisme, stabilitas membran sel dan komponen penting pada struktur sel didalam tubuh. Penelitian profil lipid ikan gelodok dilakukan dengan pemeriksaan kolesterol total, trigliserida, High Density Lipoprotein (HDL), dan Low Density Lipoprotein (LDL). Penelitian ini bertujuan untuk mengetahui dan menganalisa profil lipid yang ada pada ikan gelodok (Periothalmodon schlosseri) di perairan desa Kuala Lupak dan desa Tanipah, Kalimantan Selatan. Rancangan penelitian dilakukan secara eksploratif dengan menentukan lokasi pengambilan sampel. Teknik pengambilan sampel yang dilakukan adalah purposive sampling atau pengambilan sampel secara isidental berdasarkan pertimbangan heterogenitas lokasi sampel. Pemeriksaan profil lipid dilakukan dengan metode enzimatik. Hasil yang diperoleh pada penelitian ini yaitu profil lipid ikan timpakul pada perairan desa Tanipah mengandung kolesterol total sebanyak 101.17±36.06 mg/dL, HDL Kolesterol 26.5±7.06 mg/dL, LDL Kolesterol 50±26.9 mg/dL dan trigliserida sebanyak 134.8±146.07 mg/dL, sedangkan hasil profil lipid pada desa Kuala Lupak mengandung kolesterol total sebanyak 76.09±25.7 mg/dL, HDL Kolesterol 24±11.3 mg/dL, LDL Kolesterol 27.8±16.2 mg/dL, dan trigliserida 97.3±90.2 mg/dL, berdasarkan hasil yang didapatkan mengindikasikan bahwa kadar profil lipid pada ikan gelodok memiliki nilai yang lebih rendah dibandingkan dengan nilai kadar normal ikan pada umumnya.Lipids are a group of natural molecules that important role as fuel metabolism, cell membrane stability and important components of cell structure in the body. The research of lipid fish lipid profiles was carried out by examining total cholesterol, triglycerides, High Density Lipoprotein (HDL), and Low Density Lipoprotein (LDL). This research aims to determine and analyze the existing lipid profile in the gelodok (Periothalmodon schlosseri) in the waters of Kuala Lupak and Tanipah villages, South Kalimantan. The research design was carried out exploratively by determining the location of sampling. The sampling technique used was purposive sampling based on consideration of heterogeneity of sample locations. Lipid profile examination was carried out using an enzymatic method. The results obtained in this study are the lipid profile of the lead fish in the waters of Tanipah village containing total cholesterol as much as 101.17 ± 36.06 mg / dL, HDL Cholesterol 26.5 ± 7.06 mg / dL, LDL Cholesterol 50 ± 26.9 mg / dL and triglycerides as much as 134.8 ± 146.07 mg / dL, while the results of the lipid profile in Kuala Lupak village contained 76.09 ± 25.7 mg / dL total cholesterol, HDL Cholesterol 24 ± 11.3 mg / dL, Cholesterol LDL 27.8 ± 16.2 mg / dL, and triglycerides 97.3 ± 90.2 mg / dL, based on the results obtained indicate that the lipid profile level in the mackerel fish has a lower value than the normal value of fish in general.Keywords: lipid, Perithalmodon schlosseri, total cholesterol, Lipoprotein, Triglycerides
Introduksi Teknologi DNA Barcoding kepada Staf UPTD Perikanan Budidaya Air Payau dan Laut Karang Intan: Introduction of DNA Barcoding Technology to UPTD Staff of Brackish and Marine Aquaculture Karang Intan Sasmita, Rani; Hidayaturrahmah, Hidayaturrahmah; Badruzsaufari, Badruzsaufari; Firnanda, Muhammad Riyan; Fitri, Muhammad
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 4 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i4.7056

Abstract

Partners in community service activity are UPTD Brackish and Marine Aquaculture, Karang Intan, one of the centers under South Kalimantan Province that specializes in the hatchery of local fish such as snakehead (Channa striata), common carp (Cyprinus carpio), and climbing perch (Anabas testudineus). The problem in the partner is fish farming that still relies on seeds from nature, which causes several problems, such as slow seed growth, decreased production quality, disease attacks and hereditary abnormalities that are getting higher due to interbreeding. Based on these problems, the team collaborated with the UPTD for Brackish and Marine Aquaculture, Karang Intan, to improve the genetic quality of fish by introducing DNA barcoding techniques, especially at the spawning stage. The introduction of DNA barcoding technology is carried out through (1) classical counseling and group discussions, 2) training and assistance covering technical aspects of DNA barcoding (fish DNA isolation, DNA amplification, visualization of PCR products with electrophoresis, to the sequencing). Based on the evaluation, 100% of the participants were enthusiastic and realized the importance of DNA barcoding techniques to produce superior broodstock and fish fry, especially for snakehead, common carp, and climbing perch commodities.
Analysis of Amino Acid Profiles in Bone, Oil, and Muscle Tissue and Wound Healing Activity of Pangasius hypophthalmus Oil in Rattus norvegicus Hidayaturrahmah, Hidayaturrahmah; Suprayogi, Agik; Hanif, Novriyandi; Roosita, Katrin; Darusman, Huda Shalahudin; Aprilyana, Lia
Borneo Journal of Pharmacy Vol. 8 No. 1 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i1.8182

Abstract

Patin (Pangasius hypophthalmus), a commercially important freshwater fish, is a rich source of protein containing both essential and non-essential amino acids, crucial for various biological functions. This study aimed to determine the amino acid composition of muscle tissue, oil, and bones of P. hypophthalmus and evaluate the wound healing potential of its oil extract in Rattus norvegicus. High-Performance Liquid Chromatography was employed to quantify the levels of essential and non-essential amino acids in each tissue. Results revealed that P. hypophthalmus oil exhibited the highest total amino acid content, particularly rich in histidine, arginine, and lysine. The wound healing activity of P. hypophthalmus oil extract was assessed in a rodent model, demonstrating a significant reduction in wound area (0.62-0.84 mm) and an impressive wound healing percentage (79-84.45%). These findings suggest that different parts of P. hypophthalmus possess valuable nutritional and therapeutic properties. Notably, the high amino acid content of P. hypophthalmus oil, particularly essential amino acids, highlights its potential as a promising source for developing pharmaceutical products, including amino acid supplements, wound healing agents, and formulations for metabolic support. Further research is warranted to fully explore the therapeutic potential of P. hypophthalmus oil and its bioactive components.
Effects of patin fish-based nutritional intervention on biochemical and physiological recovery in malnourished rats: An in vivo study and its implications for clinical nutrition Hidayaturrahmah, Hidayaturrahmah; Suprayogi, Agik; Darusman, Huda S.; Roosita, Katrin; Hanif, Novriyandi
Narra J Vol. 5 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i2.1811

Abstract

Malnutrition is a major global health concern, especially in developing countries. Although patin fish oil and protein offer benefits, their individual and combined effects on maternal physiology remain unclear, particularly during early pregnancy. The aim of this study was to assess the effect of patin-based nutritional intervention on total serum protein, albumin, hemoglobin levels, body weight during pregnancy, body weight during lactation, heart rate, respiratory rate, body temperature, external appearance, behavioral activity, and milk production in malnourished rats. An in vivo study was conducted using Rattus norvegicus rats. The rats were divided into six groups: (1) healthy control, receiving standard feed; (2) malnourished control, receiving an 8% low-protein diet; (3) malnourished group, receiving standard feed; (4) malnourished treated with patin oil; (5) malnourished treated with patin meat; and (6) malnourished treated with a combination of patin oil and meat. The treatment consisted of 21 days during pregnancy and 23 days during lactation, for a total of 44 days. Our data indicated that patin-based intervention significantly increased total protein (p=0.044), albumin (p=0.001), and hemoglobin levels (p=0.034) compared to malnourished control group. The malnourished animals treated with patin oil showed the highest increases in total protein (1.67%), albumin (17.75%), and hemoglobin (24.26%). Body weight gain improved significantly in patin-treated group in both pregnancy (p=0.032) and lactation (p<0.001) compared to the malnourished control, with the highest gains observed in the patin oil group. Milk production also increased significantly (p<0.05), reaching its peak in the patin oil and meat combination group (6.97 g). Physiological parameters, including heart rate (p=0.021), respiratory rate (p=0.025), and body temperature (p=0.023), were significantly different among groups, of which patin oil and meat groups had the most optimal parameters compared to malnourished control group. In conclusion, patin-based nutritional intervention effectively enhances protein metabolism, hematological parameters, and physiological health in malnourished maternal rats, with patin oil demonstrating the most pronounced effects.
Co-Authors A.A. Ketut Agung Cahyawan W Agik Suprayogi Aprilyana, Lia Badruzsaufari Badruzsaufari Dewita Rinowati Fauzi, Rakhmat Firnanda, Muhammad Riyan Gusti Maharani Heri Budi Santoso Huda Shalahudin Darusman Katrin Roosita Muhamat Muhamat Muhamat Muhamat Muhammad Fitri, Muhammad Nita Azhari Novriyandi Hanif Sasmita, Rani