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All Journal Widya Warta Jurnal Florea JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Penelitian Farmasi Indonesia Pharmed: Journal of Pharmaceutical Science and Medical Research Humanism : Jurnal Pengabdian Masyarakat Biospektrum Jurnal Biologi Peka: Jurnal Pengabdian Kepada Masyarakat JOMPA ABDI: Jurnal Pengabdian Masyarakat Pharmaqueous Jurnal Mahasiswa Ilmu Kesehatan Jurnal Sains dan Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Strada Journal of Pharmacy
Antonius Budiawan
Universitas Katolik Widya Mandala Surabaya
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Purslane Herb (Portulaca grandiflora) Ointment Antibacterial Potency against Staphylococcus aureus Purwanto, Agus; Budiawan, Antonius; Nugroho, Christianto Adhy; Indriasari, Christina
Florea : Jurnal Biologi dan Pembelajarannya Vol. 11 No. 2 (2024)
Publisher : UNIVERSITAS PGRI MADIUN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25273/florea.v11i2.21368

Abstract

Recent research showed that the rose-like purslane (Portulaca grandiflora) magenta flower variety herbs ethanolic extract has antimicrobial potency. This research aims to determine the purslane herbs (Portulaca grandiflora) extract ointment antimicrobial potency against Staphylococcus aureus. Ointment base formulation contained of vaseline album, cera alba, adeps lanae, paraffin liquidum, cetyl alcohol, nipagin, and nipasol. Extract ointment was prepared by mixing the extract with 10, 20, and 30% concentrations into the ointment base. The antimicrobial activity test conducted in vitro using the paperdisk difussion method. The antimicrobial activity test result of the three extract concentrations of ointments showed that the 30% extract ointment had antimicrobial effect on Staphylococcus aureus with 0.81±0.03cm of clear zone. The antimicrobial activity test demonstrated that 30% purslane herbs (Portulaca grandiflora) extract ointment has a potency as antimicrobial against Staphylococcus aureus.
Pelatihan Pembuatan Mayones Sehat Berbahan Dasar Susu dan Virgin Coconut Oil (VCO) Kirana, Bida Cincin; Cahyani, Erlien Dwi; Indriasari, Christina; Puradewa, Levi; Budiawan, Antonius; Imawati, Maria Fatmadewi; Purwanto, Agus
Jompa Abdi: Jurnal Pengabdian Masyarakat Vol. 3 No. 4 (2024): Jompa Abdi: Jurnal Pengabdian Masyarakat
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jompaabdi.v3i4.1272

Abstract

Program pengabdian kepada masyarakat bekerjasama dengan PKK di lingkungan Kelurahan/Kecamatan Karangrejo Kabupaten Magetan, Jawa Timur. Melalui edukasi dan pelatihan pembuatan mayones sehat berbahan dasar susu dan Virgin Coconut Oil (VCO) ini untuk pemenuhan nutrisi pada ibu, ibu hamil dan anak-anak sebagai upaya pencegahan stunting. Stunting merupakan bentuk kegagalan pertumbuhan, kurang gizi kronik yang berlangsung lama dan penyebab yang bersifat akut. Penurunan angka stunting merupakan salah satu indikator pencapaian Sutainable Development Goals (SDG’s) yang ke-2 yaitu menghilangkan kelaparan, mencapai ketahanan pangan dan gizi yang baik serta meningkatkan pertanian berkelanjutan. Kegiatan ini bertujuan meningkatkan pengetahuan terkait pencegahan stunting dengan pemenuhan nutrisi baik bagi ibu maupun anak-anak dalam mencegah kejadian stunting. Hasil pengabdian kepada masyarakat dalam mitra yang merupakan PKK di lingkungan Kelurahan/Kecamatan Karangrejo Kabupaten Magetan, Jawa Timur yang mengikuti edukasi serta pelatihan sebagian besar dapat membuat mayones sehat berdasarkan formula yang telah diberikan. Terjadi peningkatan pengetahuan mitra setelah mengikuti pelatihan sebesar 7,5 dari 76,25 menjadi 83,75.
Sunscreen Activity of Soursop Seeds Extract Erlien Dwi Cahyani; Antonius Budiawan; Levi Puradewa
Strada Journal of Pharmacy Vol. 4 No. 1 (2022): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i1.49

Abstract

Indonesia is a tropical climate country that is rich in sunlight. Sunlight overexposure leads to skin damage such as sunburn, black spots, wrinkles, and aging skin which is caused by oxidative stress. Soursop is a fruit rich in flavonoids that has the antioxidant activity to prevent oxidative stress and is known for its sunscreen effect. This study was aimed to determine the sunscreen activity of soursop seed extract by Sun Protective Factor (SPF) parameter. Soursop extract divided to 0.15 and 0.25% concentration and the SPF value was measured quantitatively using Spectrophotometer UV-Vis. SPF measurement result showed that soursop seeds extract 0.15 and 0.25% concentration gives 4.35 and 7.38 respectively SPF value. Soursop seeds extract showed sunscreen activity with low protection category.
Uji Fisik Dan Stabilitas Formulasi Sediaan Masker Gel Dari Ekstrak Daun Beluntas (Pluchea Indica L.) dengan Variasi Karbopol sebagai Gelling Agent Rahmawati, Zendy Lia Ayu; Budiawan, Antonius; Puradewa, Levi
Jurnal Mahasiswa Ilmu Kesehatan Vol. 3 No. 3 (2025): Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v3i3.3159

Abstract

Beluntas (Pluchea indica L.) contains of flavonoids, which are beneficial for treating acne. Previous research has been conducted on peel-off gel masks made from ethanol extract of beluntas leaves. The aim of this study is to determine the variation in carbopol concentrations in the formulation of gel masks containing beluntas leaf extract, as well as to evaluate their physical stability. This research using three formulations with different carbopol concentrations: Formula I with 1% carbopol, Formula II with 1.5% carbopol, and Formula III with 2% carbopol. The physical evaluation of the beluntas leaf extract gel mask preparations included organoleptic, homogeneity, viscosity, pH, spreadability, and adhesiveness testing. All formulations underwent a stability test known as the cycling test (cycles 1 to 6). The results of the stability tests showed that Formulas II and III met the requirements for physical quality, whereas Formula I did not meet the viscosity and spreadability value ranges. The gel mask with the best results was Formula II with 1.5% carbopol concentration. However, based on the cycling stability test, there was an increase in viscosity and adhesiveness. Based on the cycling test results for organoleptic properties, homogeneity, and spreadability, Formula II did not show significant changes.
Pelatihan Pembuatan Minyak Esensial Sereh (Cymbopogon nardus) Menggunakan Teknologi Sederhana Indriasari, Christina; Budiawan, Antonius; Puradewa, Levi; Cincin Kirana, Bida; Purwanto, Agus; Cahyani, Erlien Dwi; Imawati, Maria Fatmadewi
Humanism : Jurnal Pengabdian Masyarakat Vol 4 No 3 (2023): Desember
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/hm.v4i3.19172

Abstract

Desa Ngunut berada di wilayah Kecamatan Kawedanan, Kabupaten Magetan yang sebagian besar penduduknya menggantungkan hidup dari bercocok tanam. Dari segi ekonomi, sebanyak 27% warga Desa Ngunut, Kecamatan Kawedanan merupakan keluarga pra sejahtera, sehingga diperlukan upaya untuk dapat meningkatkan perekonomian keluarga di wilayah mitra melalui pemberdayaan potensi warga. Salah satu upaya peningkatan perekonomian melalui pemanfaatan tanaman sereh yang berpotensi dikembangkan untuk mengembangkan usaha perekonomian dari hulu ke hilir akan tetapi belum menjadi komoditas di wilayah Desa Ngunut. Hal ini dikarenakan warga belum memahami manfaat dan potensi ekonomi dari tanaman sereh. Kegiatan pengabdian kepada masyarakat ini dilakukan melalui penyuluhan untuk memperkenalkan manfaat dan potensi ekonomi tanaman sereh (Cymbopogon nardus), serta pembuatan minyak esensial sereh menggunakan alat destilasi sederhana. Luaran yang dicapai adalah peningkatan pengetahuan dan pemahaman secara keseluruhan dari 68,67% menjadi 84,33% pada warga Desa Ngunut, Kecamatan Karangrejo, Kabupaten Magetan mengenai tanaman sereh (Cymbopogon nardus) yang dapat dimanfaatkan untuk meningkatkan perekonomian warga
Aktivitas Penyembuhan Luka Ektstrak Herba Krokot (Portulaca Oleracea) Budiawan, Antonius; Purwanto, Agus; Puradewa, Levi
Pharmaqueous: Jurnal Ilmiah Kefarmasian Vol. 3 No. 1 (2021): Volume 3, Nomor 1, Mei 2021
Publisher : Universitas Al-Irsyad Cilacap

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36760/jp.v3i1.270

Abstract

Krokot (Portulaca oleracea) merupakan tanaman yang secara tradisional digunakan sebagai olahan pangan dan tanaman hias. Hasil penelitian terbaru menunjukkan bahwa krokot memiliki aktivitas antibakteri yang kuat sehingga dapat dikembangkan untuk pengujian aktivitas penyembuhan luka berkaitan dengan kandungan flavonoidnya. Penelitian ini bertujuan untuk mengetahui kemampuan penyembuhan luka dan kandungan flavonoid total ekstrak herba krokot (Portulaca oleracea). Uji aktivitas penyembuhan luka dilakukan menggunakan hewan uji kelinci yang diinduksi luka dengan ukuran 8 mm. Luka kemudian dikelompokkan menjadi empat kelompok uji yaitu kelompok kontrol negatif (diberi aqua destilata), kontrol positif (diberi betadine solution), ektrak herba krokot konsentrasi 10% dan 20%. Hasil uji menunjukkan aktivitas penyembuhan luka yang berbeda signifikan dengan kelompok kontrol negatif pada kelompok yang diberi ekstrak 10 dan 20% dengan rata-rata diameter luka berturut-turut sebesar 4,14±1,30 dan 4,56±1,93 di hari ke-7, 0,81±1,40 dan 0,52±0,90mm di hari ke-11. Uji kandungan flavonoid total ekstrak herba krokot menunjukkan rata-rata hasil 3,27±0,19 mgEQ/g.
Potensi Fraksi Ekstrak Herba Krokot (Portulaca grandiflora) Varietas Bunga Magenta dalam Menyembuhkan Luka: The Magenta Flower Variety Purslane Herbs (Portulaca grandiflora) Extract Fraction Potency in Wound Healing Budiawan, Antonius; Puradewa, Levi; Kirana, Bida Cincin
Jurnal Sains dan Kesehatan Vol. 6 No. 2 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i2.2025

Abstract

Purslane rose-like flower variety (Portulaca grandiflora) is a popular decorative plant in society. Purslane utilization for health in Indonesia is still limited. Rose-like magenta flower variety purslane (P. grandiflora) is already known for its wound healing activity. This wound healing activity may occur from its secondary metabolites such as flavonoids, saponins, tannins, and terpenoids. Flavonoids extracted in a suitable solvent have the potency to increase the purslane wound healing activity. This research aimed to determine the magenta flower variety purslane herbs extract fraction potency in wound healing. This experimental research was conducted using wound-induced rabbits. The wounds were divided into negative and positive control groups, water, ethyl acetate, and n-hexane treatment groups. The wounds treated with aqua destilata re-epithelization was 12.33 ± 0.94 days, meanwhile, the wounds treated with betadine solution, water, ethyl acetate, and n-hexane fraction were 9.33 ± 0.47, 9.33 ± 0.47, 9.67 ± 0.47, dan 10.00 ± 0.00 days respectively. The water, ethyl acetate, and n-hexane fraction of magenta flower variety purslane herbs (P. grandiflora) have potency in wound healing. The water fraction showed the fastest re-epithelization pace compared to ethyl acetate and n-hexane fraction.   Keywords:          fraction, purslane, Portulaca grandiflora, magenta, wound healing   Abstrak Krokot varietas berbunga seperti mawar (Portulaca grandiflora) merupakan tanaman hias yang cukup populer di masyarakat. Di Indonesia pemanfaatan krokot untuk kesehatan masih sangat terbatas. Krokot mawar (P. grandiflora) varietas bunga magenta diketahui memiliki aktivitas penyembuhan luka. Aktivitas penyembuhan luka tersebut kemungkinan diperoleh karena kandungan metabolit sekunder seperti flavonoid, saponin, tanin, dan terpenoid. Flavonoid yang tertarik dalam pelarut yang sesuai tersebut berpotensi meningkatkan kemampuan krokot dalam menyembuhkan luka. Penelitian ini bertujuan mengetahui potensi dari fraksi ekstrak herba krokot (P. grandiflora) varietas bunga magenta dalam menyembuhkan luka. Penelitian eksperimental ini dilakukan menggunakan kelinci yang diinduksi luka pada bagian punggung. Luka dibagi menjadi kelompok kontrol negatif dan positif serta kelompok perlakuan fraksi air, etil asetat, dan n-heksana. Kelompok luka yang diberi aqua destilata menunjukkan re-epitelisasi 12.33 ± 0.94 hari, sedangkan kelompok luka yang diberi betadine solution, fraksi air, etil asetat, dan n-heksana berturut-turut 9.33 ± 0.47, 9.33 ± 0.47, 9.67 ± 0.47, dan 10.00 ± 0.00 hari. Fraksi air, etil asetat, dan n-heksana herba krokot (P. grandiflora) memiliki potensi menyembuhkan luka dengan mempercepat laju re-epitelisasi. Fraksi air menunjukkan laju re-epitelisasi yang paling baik dibandingkan fraksi etil asetat dan n-heksana.   Kata Kunci:         fraksi, krokot, Portulaca grandiflora, magenta, penyembuhan luka
Pelatihan Pembuatan Pupuk Organik Cair Di Kelurahan Rejomulyo Kecamatan Kartoharjo Kota Madiun Ganjari, Leo Eladisa; Nugroho, Christianto Adhy; Purwanto, Agus; Budiawan, Antonius; Puradewa, Levi
Jompa Abdi: Jurnal Pengabdian Masyarakat Vol. 4 No. 3 (2025): Jompa Abdi: Jurnal Pengabdian Masyarakat
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jompaabdi.v4i3.1359

Abstract

Masyarakat Kelurahan Rejomulyo Kota Madiun saat ini sedang melaksanakan Program Pekarangan Pangan Lestari (P2L), yaitu kegiatan penanaman tanaman pangan di lahan pekarangan rumah masing-masing. Permasalahan utama yang dihadapi mitra adalah bagaimana memanfaatkan sumber daya lingkungan sekitar untuk menyediakan pupuk yang murah dan alami. Dalam proses komunikasi dengan mitra, diketahui bahwa ketersediaan pupuk organik yang terjangkau menjadi kendala penting dalam mendukung program ketahanan pangan melalui budidaya tanaman pangan. Sebagai solusi, diusulkan pembuatan pupuk organik dengan memanfaatkan potensi sumber daya yang ada di Kelurahan Rejomulyo. Harapannya, wilayah ini dapat berkembang menjadi desa mandiri pupuk organik. Kegiatan pengabdian kepada masyarakat yang dilaksanakan meliputi pembuatan pupuk organik cair dan padat dengan menggunakan bahan tunggal berupa kotoran hewan (kohe) kambing. Hasil kuesioner mengenai pemahaman pembuatan pupuk organik cair berbahan kohe kambing menunjukkan adanya peningkatan pengetahuan mitra dengan rata-rata skor sebesar 9,34%, yaitu dari skor 81,07 sebelum pelatihan menjadi 90,41 setelah pelatihan. Peningkatan ini mengindikasikan bahwa terdapat pengetahuan baru yang diperoleh mitra, sehingga menambah wawasan sekaligus keterampilan mereka dalam mengolah pupuk organik cair.
Protective Factor Evaluation of Purslane (Portulaca grandiflora) Magenta Flower Variety Herbs Extract Cream Formula Kirana, Bida Cincin; Cahyani, Erlien Dwi; Budiawan, Antonius
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 10 No. 3 (2023): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v10i32023.379-385

Abstract

Background: Indonesia is an equatorial country that is rich in sunlight all year. UV light is divided into three wavelength groups: UV-A (320-400nm), UV-B (280-320nm), and UV-C (100-290nm). Intracell chromophores in skin cell membranes such as riboflavin, porphyrin, nicotinamide, and enzymes will absorb the UV-A light. The UV-B light penetrates the dermis layer and causes DNA structure changes, which lead to wrinkles and a rising risk of skin cancer. Premature skin aging and skin cancer can be prevented with sunscreen preparation containing compounds that can protect the skin from UV radiation. Flavonoid is one of the purslane (Portulaca grandiflora) active metabolites that have the potency to be developed as sunscreen. Objective: This research aimed to determine the ability of purslane (Portulaca grandiflora) magenta flower variety herbs extract cream as a sunscreen as indicated by the %Te, %Tp, and Sun Protective Factor value. Methods: This research was an experimental study with various purslane magenta flower variety herbs extract cream formulas that were tested for their %Te, %Tp, and SPF value with a UV-Vis spectrophotometer. Results: The sunscreen cream preparation with 2.5% of purslane (Portulaca grandiflora) magenta flower variety herb extract had %Te, %Tp, and SPF values of 25.86 ± 2.41%, 36.05 ± 2.82%, and 3.97 ± 0.35 respectively. At the same time, preparations with 5% concentration of extract had %Te, %Tp, and SPF values of 8.23 ± 0.86%, 16.65 ± 0.92%, and 8.03 ± 0.38, respectively. Conclusion: The sunscreen activity of all extract concentration creams was significantly different compared to the negative control (cream base) in all parameters. Flavonoids are the compounds responsible for the sunscreen activity of purslane extract.
EFEKTIVITAS EKSTRAK DAUN BELIMBING WULUH (Averrhoa bilimbi L.) SECARA TOPIKAL TERHADAP PENYEMBUHAN LUKA PADA KELINCI (Oryctolagus cuniculus) Richa Dwi Novita Sari; Antonius Budiawan; Angga Rahabistara Sumadji
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 9 No. 1 (2023): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v9i1.660

Abstract

Wound healing is a repair process of damaged skin tissue caused by injury. The bilimbi (Averrhoa bilimbi L.) plant is widely known to have potential in wound healing and the plant part that is commonly used is the leaves. The purpose of this study was to determine the wound healing effects of bilimbi leaf extract (Averrhoa bilimbi L.) on rabbits (Oryctolagus cuniculus) topically. The wound healing test was conducted using the New Zealand strain rabbit test animal. The rabbit’s back skin was induced with 8 mm diameter wound and the induced wounds were grouped into 5 groups. The groups included a negative control group that was given with aqua dest solution; the positive control group was given with betadine solution; treatment groups were given with 3%; 6%; and 12% bilimbi leaves extract. The wounds that were treated with betadine solution and bilimbi leaves extract 3% healed on day 13th. The wounds that were treated with bilimbi leaves extract 6 and 12% were healed on day 12nd. The different results showed by the wounds that were treated with aqua destilata which were healed on day 14th. The results showed that bilimbi leaf extract was topically effective in wound healing on rabbit test animals. The most effective concentration of bilimbi leaves extract in wound healing was 6% and 12%.
Co-Authors AGUS PURWANTO Agus Purwanto Alfinda Dwi Aprillyanti Angga Rahabistara Sumadji Bida Cincin Kirana Cahyani, Erlien Dwi Christianto Adhy Nugroho Christianto Adhy Nugroho Erlien Dwi Cahyani Imawati, Maria Fatmadewi Indriasari, Christina Kirana, Bida Cincin Leo Eladisa Ganjari Levi Puradewa Maria Fatmadewi Imawati Nova Yastika Sari Nur Wijayanti, Andita Nurcahyani, Diah Rahmawati, Zendy Lia Ayu Richa Dwi Novita Sari Vidya Kartikaningrum Yustika Aprilia Maudyana