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All Journal Widya Warta Jurnal Florea JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Penelitian Farmasi Indonesia Pharmed: Journal of Pharmaceutical Science and Medical Research Humanism : Jurnal Pengabdian Masyarakat Biospektrum Jurnal Biologi Peka: Jurnal Pengabdian Kepada Masyarakat Media Farmasi Indonesia JOMPA ABDI: Jurnal Pengabdian Masyarakat Pharmaqueous Jurnal Farmasi Klinik dan Sains Jurnal Mahasiswa Ilmu Kesehatan Jurnal Sains dan Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Strada Journal of Pharmacy
Antonius Budiawan
Universitas Katolik Widya Mandala Surabaya
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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FORMULATIONS OF ANTIOXIDANT Saccharum officinarum (Linn.) LEAFS EXTRACT LOTION WITH DPPH (1,1- Diphenyl-2- Picryhydrazyl) Wijayanto, Arif; Herdianty, Juvita; Budiawan, Antonius
Jurnal Farmasi Klinik dan Sains Vol 5, No 2 (2025): Jurnal Farmasi Klinik dan Sains
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Muhammadiyah Gombong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26753/jfks.v5i2.1751

Abstract

Ekstrak daun Saccharum officinarum (SO) mengandung asam fenolat dan flavonoid aglikon trisin (5,7,4-trihidroksi-3,5-dimetoksiflavon). Senyawa fenolik dan flavonoid dalam SO telah dilaporkan memiliki aktivitas antioksidan, antiinflamasi, antimutagenik, dan sebagai inhibitor tirosinase yang kuat. Losion merupakan sediaan kosmetik yang berfungsi untuk melembapkan dan melindungi kulit dengan memberikan efek menenangkan. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh variasi konsentrasi ekstrak daun SO terhadap kualitas fisik dan aktivitas antioksidan losion. Penelitian ini merupakan studi eksperimental yang melibatkan formulasi losion dengan konsentrasi ekstrak daun SO sebesar 2,5%, 5%, dan 7,5%. Aktivitas antioksidan dievaluasi menggunakan metode DPPH (1,1-Difenil-2-Pikrilhidrazil) untuk mengukur kemampuan ekstrak dalam menangkap radikal bebas. Hasil menunjukkan bahwa losion ekstrak daun SO memiliki tekstur lembut, warna hijau, dan aroma khas daun SO. Uji pH, viskositas, daya lekat, dan uji daya sebar memiliki nilai signifikansi 0,00
Effect Of Cetyl Alcohol Variation On Formulation And Stability Of Belimbing Wuluh Leaf Extract (Averrhoa Bilimbi L.) Cream Antonius Budiawan; Febriana Alfianingrum; Bida Cincin Kirana; Erlien Dwi Cahyani
Media Farmasi Indonesia Vol. 21 No. 1 (2026): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v21i1.348

Abstract

Belimbing wuluh (Averrhoa bilimbi L.) extract has been shown to have antioxidant activity, which can help prevent skin wrinkles. This extract also has the potential to be formulated into a cream. Cetyl alcohol is a common thickener and emulsifier in a cream formulation. This study investigated the effect of cetyl alcohol concentration variation on physical properties and stability of belimbing wuluh (Averrhoa bilimbi L.) cream preparation. The extract was formulated into three creams with different cetyl alcohol concentrations: FI (3% cetyl alcohol), FII (4% cetyl alcohol), and FIII (5% cetyl alcohol). The creams were evaluated for their physical characteristics, including organoleptic properties, homogeneity, cream type, adhesion, spreadability, pH, and viscosity. Stability was tested using a Freeze and Thaw Cycling Test over six cycles. The results of the physical evaluation showed that all three formulations were good oil-in-water (O/W) creams, with the exception of FIII, which had spreadability below the standard range. The stability test revealed that FI and FII were unstable, as indicated by changes in their adhesion, spreadability, and viscosity. In contrast, FIII demonstrated good stability across all evaluations. In conclusion, the concentration of cetyl alcohol significantly impacted the physical properties and stability of the belimbing wuluh extract cream.
Co-Authors AGUS PURWANTO Agus Purwanto Alfinda Dwi Aprillyanti Angga Rahabistara Sumadji Arif Wijayanto, Arif Bida Cincin Kirana Cahyani, Erlien Dwi Christianto Adhy Nugroho Christianto Adhy Nugroho Erlien Dwi Cahyani Febriana Alfianingrum Imawati, Maria Fatmadewi Indriasari, Christina Juvita Herdianty Kirana, Bida Cincin Leo Eladisa Ganjari Levi Puradewa Maria Fatmadewi Imawati Nova Yastika Sari Nur Wijayanti, Andita Nurcahyani, Diah Rahmawati, Zendy Lia Ayu Richa Dwi Novita Sari Vidya Kartikaningrum Yustika Aprilia Maudyana