Garuda - Garba Rujukan Digital

p-Index From 2021 - 2026

2.66

P-Index

This Author published in this journals

All Journal Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Bioscientia Medicina : Journal of Biomedicine and Translational Research Medika Kartika : Jurnal Kedokteran dan Kesehatan Bioscientia Medicina : Journal of Biomedicine and Translational Research MEDICINUS

Endra Yustin Ellistasari

Unknown Affiliation

Author-ID : 3712747

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Veterinary

Published : 19 Documents Claim Missing Document

Claim Missing Document

Articles

Title

Analisis In Silico pada VCO untuk Terapi Dermatitis Atopik Mardiana; Primadhanty B; Adniana N; Halim PK; Didik H. Utomo; Endra Yustin Ellistasari; Suci Widhiati
MEDICINUS Vol. 33 No. 3 (2020): MEDICINUS
Publisher : PT Dexa Medica

Introduction: In silico analysis is used in the early stages of drug discovery to speed the rate of discovery that is considered cost and time-efficient. Virgin Coconut Oil (VCO) is a treatment option for atopic dermatitis because it has function to repair skin barrier and as anti-inflammation. Objective: To evaluate the VCO content using computational in silico analysis for the treatment of atopic dermatitis. Methods: The active compounds of Cocos nucifera extracted from KNApSAcK database were predicted experimentally and analyzed computationally using Simple Molecular-Input Line-Entry System (SMILES), Prediction of Activity Spectra for biologically active Substances (PASS) server, and Search Tool for Interactions of Chemicals (STITCH). Results: There are 19 active compounds found in VCO. The analysis shows that VCO has free fatty acid (FFA) protein which acts as a receptor for long and medium chain saturated and unsaturated fatty acids. The highest potential bioactivity of active VCO compounds was as antieczema, with the most important component was linoleic acid, with an average value of probable to be active (Pa) = 0.872, predicted to be highly potential in computational and laboratory tests. Conclusion: Based on this study, we recommend the use of VCO as treatment for atopic dermatitis because VCO has anti-inflammatory potential bioactivity, histamine inhibitor, improves skin barrier function and antieczema which could improve the outcome of atopic dermatitis.

Laporan Kasus Pyoderma Gangrenosum disertai Kandidiasis Kutis pada Wanita dengan Sindrom Metabolik Ambar Aliwardani; Fiska Rosita; Putti Fatiharani; Endra Yustin Ellistasari
MEDICINUS Vol. 35 No. 1 (2022): MEDICINUS
Publisher : PT Dexa Medica

Introduction: Pyoderma gangrenosum (PG) is a rare inflammatory disease characterized by sterile, predominantly neutrophilic infiltration of the skin and other organs. PG is found particularly in women aged between 40-60 years. Metabolic syndrome is reported to have a potential role to induce PG. Case: A 45-year-old woman came to Dr. Moewardi Hospital with chief complaints of ulcer in the chest and legs that was preceded by reddish fluid filled bump which then broke into painful wound. History of trauma, gastrointestinal, and joint pain was denied. Dermatological examination of anterior trunk region and inferior extremity showed erythematous patches with multiple ulcers with irregular border covered with hemorrhagic crusts and necrotic tissue. Pathergy test was negative. In the right and left axillary, inframammary and inguinal, there were hyperpigmented patches with scales and satellite lesions, KOH 10% examination obtained pseudohyphae and cell budding. The patient also has metabolic syndrome. Diagnosis of PG was made based on the presence of 2 major and 2 minor criteria. Patient was given intravenous methylprednisolone 93.75 mg/24 hours, analgesics, antibiotics, topical antifungals, debridement and breast reconstructive surgery after response to steroid therapy was seen. The patient was discharges from hospital with improvement. Discussion: Metabolic syndrome is considered to be a risk factor contributing to the development of systemic chronic inflammatory processes and has been described as one of the precipitating factors for PG and skin candidiasis. Management of metabolic syndrome as the known risk factor aims to minimize the recurrence of PG in the future.

Modalitas Terapi Vitiligo pada Anak Nathania Amelinda; Endra Yustin Ellistasari; Indah Julianto
MEDICINUS Vol. 35 No. 3 (2022): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/medicinus.v35i3.106

itiligo is a pigmentation disorder characterized by depigmented patches on skin and hair due to functional loss of melanocytes. Vitiligo in children is generally associated with other autoimmune diseases and has serious cosmetic and psychosocial impact. Treatment modalities for vitiligo in children consist of topical therapy, phototherapy, systemic therapy, and surgery. Vitiligo in children has a relatively good prognosis compared to adult cases. Repigmentation in childhood vitiligo usually happen spontaneously and relapses are rare.

Fototerapi pada Dermatologi Anak Wibisono Nugraha; Endra Yustin Ellistasari
MEDICINUS Vol. 36 No. 3 (2023): MEDICINUS
Publisher : PT Dexa Medica

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56951/b5jqva33

Phototherapy is a non-ionizing ultraviolet (UV) radiation therapy used as a treatment for several medical conditions. The mechanism of action of phototherapy is to act as antiproliferative, induce apoptotic, and provide immunosuppressive effect. Several therapeutic modalities that can be used as alternative therapy in children include NB-UVB, BB-UVB, ultraviolet A, PUVA, and excimer laser. Phototherapy in children is indicated especially in diseases such as psoriasis, atopic dermatitis, vitiligo, pityriasis lichenoides, and mycoses fungoides. The use of phototherapy has indications, contraindications, dose, and side effects that should be considered when choosing appropriate phototherapy in children. Common side effects are erythema, xerosis, burning sensation, and itching. Several groups of patients with refractory complaints are advised to use additional phototherapy modalities, either as monotherapy or in combination with topical and systemic therapy.

Co-Authors Achmad Satya Negara Adniana N Adniana Nareswari Ambar Aliwardani Ammarilis Murastami Arie Kusumawardani Azhar Arrosyid Benedikta Lauda Budi Eko Prasetyorini Dharmawan, Nugrohoaji Didik H. Utomo Fatimah Fitriani Fiska Rosita Frieda Yanuar Halim PK Indah Julianto Ivani Lidjaja, Lifesia Natali MARDIANA Muhammad Eko Irawanto Nathania Amelinda Novan Adi Nurrachmat Mulianto Oyong Oyong Prasetyadi Mawardi Primadhanty B Putri Oktriana Putti Fatiharani Sesia Pradestine Shelly Lavenia Sambodo Suci Widhiati Trya Oktaviani Vrenda Alia Wibisono Nugraha

Title Search

Found 4 Documents Search Journal : MEDICINUS

Abstract

Abstract

Abstract

Abstract

Title

Found 4 Documents
Search
Journal : MEDICINUS