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Perbandingan Fungsi Berkemih pada 3 Hari dan 5 Hari Katerisasi Urin Pascaoperasi Histerektomi Radikal pada Wanita Penderita Keganasan Serviks Stadium Awal Astri Novianti; Benny Hasan Purwara; Yudi Mulyana Hidayat; Sofie Rifayani Krisnadi; Maringan Diapari Lumban Tobing; Edwin Armawan
Indonesian Journal of Obstetrics & Gynecology Science Volume 1 Nomor 2 September 2018
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (142.064 KB) | DOI: 10.24198/obgynia.v1n2.88

Abstract

AbstrakTujuan: Menganalisis perbandingan fungsi berkemih pada pemakaian kateter urin selama 3 hari dan 5 hari pasca operasi histerektomi radikal.Metode: Non-inferiority randomized controlled trial. Subjek penelitian adalah penderita kanker serviks di Rumah Sakit Hasan Sadikin Bandung yang dilakukan operasi histerektomi radikal. Dilakukan penilaian fungsi berkemih dan kejadian infeksi saluran kemih sebelum dan setelah operasi hari ke−3 (kelompok intervensi) dan hari ke−5 (kelompok kontrol). Hasil: Pascaoperasi terjadi penurunan fungsi sensorik 8,5% pada kelompok intervensi dan 13,5% pada kelompok kontrol dan penurunan fungsi motorik 87,5% pada kelompok intervensi dan 150% pada kelompok kontrol. Kejadian infeksi saluran kemih meningkat 6,7% pada kelompok kontrol. Kesimpulan: Penggunaan kateter urin selama 3 hari pasca histerektomi radikal tidak lebih buruk dari 5 hari dan dapat digunakan sebagai manajemen pada penderita kanker serviks pasca histerektomi radikal. The Comparison of 3 Days and 5 Days Catheterization Following Radical Hysterectomy in Women with Early Stage Cervical Cancer: A Non-Inferiority Randomized Controlled TrialAbstractObjective: To compare the urinary function after radical hysterectomy  with catheter usage for 3 days and 5 days. Method: A non-inferiority randomized controlled trial. Subjects were women diagnosed with cervical cancer that underwent radical hysterectomy in Hasan Sadikin Hospital Bandung. The study conducted by comparing urinary function and urinary tract infection in 3 days catheterization and 5 days catheterization after radical hysterectomy. Result: Post operation, there was decreased 8,5% sensory function in intervention group and 13,5% in control group and decreased 87,5% motoric function in intervention group and 150% in control group. The urinary tract infection increased about 6,7% in control group. Conclusion:3-days urethral catheterization following radical hysterectomy is non inferior to 5 days urethral catheterization and could be used for management of women with early stage cervical cancer after radical hysterectomy. Key  words: Urinary dysfunction after radical hysterectomy, 3 and 5 days catheterization after radical hysterectomy, urinary tract infection
Hubungan gambaran spektral pulse wave doppler dengan respon klinis terapi radiasi eksternal pada kanker serviks stadium IIB-IVA Syamel Muhammad; Dodi Suardi; Maringan DL Tobing
Majalah Kedokteran Andalas Vol 41, No 1 (2018): Published in January 2018
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (19767.526 KB) | DOI: 10.22338/mka.v41.i1.p10-21.2018

Abstract

Tujuan: Mengetahui hubungan antara gambaran spektral Doppler USG transrektal Pulse Wave Doppler dengan respon klinis terapi radiasi eksternal pada kanker serviks stadium lokal lanjut (IIB-IVA). Metode: Menggunakan metode Prepost Design secara prospektif, dilakukan pemeriksaan Pulse wave Doppler menggunakan probe transrektal pada pasien kanker serviks stadium IIB-IVA. Pada pasien dilakukan pengukuran ukuran tumor secara ultrasonografi dan klinis sebagai ukuran awal tumor untuk menilai respon radiasi. Jumlah sampel adalah 60 untuk kelompok dengan hasil spektral Doppler baik dan buruk, yang dilakukan terapi radiasi eksternal dan dilakukan pengukuran masa kembali secara USG dan klinis untuk menentukan kriteria respon terapi. Hasil: Kelompok respon klinis buruk sebanyak 9 (75,0%) memiliki spektral vaskularisasi buruk dan sebanyak 3 (25,0%) memiliki spektral vaskularusasi baik sedangkan untuk respon klinis baik sebanyak 19(41,3%) memiliki spektral vaskularisasi buruk dan sebanyak 27 (58,7%) memiliki spektral vaskularisasi baik. Pada analisis dengan uji exact Fisher ditemukan hubungan yang bermakna (p<0,05) antara gambaran spectral PW Doppler transrektal dengan respon klinis terapi radiasi eksternal pada kanker serviks stadium IIB-IVA dengan nilai Relative Risk (RR) 3.214 kali. Kesimpulan: Terdapat hubungan yang bermakna antara gambaran spektral Doppler dengan respon klinis terapi radiasi eksternal pada kanker serviks stadium IIB-IVA. 
Mobile Phone Text Messaging Cross Platform Intervention for Cervical Cancer Screening: Changes in Knowledge and Attitude in Rural Areas Pre-Post Intervention Niken Bayu Argaheni; Firman F Wirakusumah; Maringan D.L. Tobing; Herry Herman; Deni K. Sunjaya; Yudi Mulyana Hidayat
JNKI (Jurnal Ners dan Kebidanan Indonesia) (Indonesian Journal of Nursing and Midwifery) Vol 8, No 2 (2020)
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/jnki.2020.8(2).123-133

Abstract

The key to the success of cervical cancer control programs is screening followed by adequate treatment. The socio-economic status gap and the low level of education lead to limited awareness and understanding of women of childbearing age. Increasing the capacity of knowledge of women of childbearing age through health education either directly or indirectly is important. Therefore, there is need to develop health education by utilizing the rapidly growing media today such as through the application of cross platform messages on smartphones. This study aims to analyze the effect of the application of health education on detection of cervical cancer through the application of cross-platform messages to increase knowledge and attitude of Women in Childbearing Age. A quasi-experimental research of pre-posttest design with control groups conducted consisting of 72 subjects of Women in Childbearing Age. Fogg's Behavior Model was the conceptual framework that guided the development of the cross-platform messaging intervention. A series of checklist from expert panel conducted to inform the development of the cross-platform messaging intervention. The messages are delivered for a 7-day period in the morning. Data collection using a checklist instrument. Univariable analysis through Rasch and bivariable modeling using numerical categorical comparative test, difference using T test. Findings revealed a significant increase in participants’ knowledge and attitude of cervical cancer screening. Women of Childbearing Age whose health education through cross-platform application has a 3.5 times probability of knowledge and good attitude compared to women of childbearing age who are not getting health education through cross-platform applications. Health education through cross-platform messaging services can be a cheap and effective method to improve the knowledge and attitude of women of childbearing age, as well as reaching individuals who have never done early detection of cervical cancer.
Hubungan antara Ekspresi Ki-67 dan Kaspase-3 dengan Respons Kemoterapi Neoajuvan pada Pasien Karsinoma Serviks Stadium IB2 dan IIA2 di Rumah Sakit Dr. Hasan Sadikin, Bandung I MADE WIDYALAKSANA MAHAYASA; MARINGAN DIAPARI LUMBAN TOBING; ALI BUDI HARSONO
Indonesian Journal of Cancer Vol 10, No 2 (2016): April - June 2016
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1302.96 KB) | DOI: 10.14414/ijoc.v10i2.425

Abstract

ABSTRACTCervical carcinoma is the second ranks cancer in women in developing countries. This study was a retrospective cohortstudy of the relationship between the role of Ki-67 expression and caspase-3 on tumor shrinkage response in cervical carcinoma stage IB2 and IIA2. A total of 41 cases have been done NACT with Cisplatin, Vincristine and Bleomycin. All samples showed expression in immunohistochemical staining for Ki-67 and caspase-3. Meanwhile, Pearson correlation analysis found no correlation between the expression levels of Ki-67 and caspase-3 with a diminution oftumor mass (p>0.05). While the correlation between the ratio of Ki-67 expression and caspase-3 with a significant diminution of tumor mass is obtained p 0.042, R-0.319, means that the higher the Ki-67 expression levels compared caspase-3 expression level then the response of the tumor mass size reduction will be better.ABSTRAKKarsinoma serviks merupakan kanker kedua terbanyak pada wanita di negara berkembang. Penelitian ini merupakan penelitian kohort retrospektif yang mempelajari hubungan antara peran ekspresi Ki-67 dan kaspase-3 terhadap respons pengecilan tumor pada karsinoma serviks stadium IB2 dan IIA2. Sebanyak 41 kasus telah dilakukan KTNA dengan Cisplatin, Vincristin, dan Bleomycin (PVB).Hasil penelitian menunjukkan seluruh sampel ekspresi pada pewarnaan imunohistokimia untuk Ki-67 dan kaspase-3. Sedangkan analisis korelasi Pearson tidak didapatkan korelasi antara tingkat ekspresi ki-67 dan kaspase-3 dengan pengecilan massa tumor dan nilai p>0,05. Sedangkan korelasi antara rasio ekspresi Ki-67 dan kaspase-3 dengan pengecilan massa tumor didapatkan bermakna dengan nilai p = 0,042 (p<0,05), R-0,319. Artinya, semakin tinggi proliferasi (tingkat ekspresi Ki-67) dibandingkan dengan apoptosis (tingkat ekspresi kaspase-3) maka respons pengecilan tumor akan semakin baik pada karsinoma serviks stadium IB2 dan IIA2