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All Journal Jurnal Anestesiologi Indonesia JURNAL GIZI INDONESIA Jurnal Kedokteran Diponegoro Medica Hospitalia
Sefri Noventi Sofia
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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HUBUNGAN ANTARA FUNGSI DIASTOLIK DENGAN DENGAN KUALITAS HIDUP PADA PASIEN GAGAL JANTUNG KRONIK DENGAN FRAKSI EJEKSI NORMAL Marchilia Widistana; Sefri Noventi Sofia; Erna Setiawati
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 5, No 4 (2016): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (371.076 KB) | DOI: 10.14710/dmj.v5i4.14810

Abstract

Latar Belakang : Gagal jantung kronik masih memiliki angka morbiditas dan mortalitas yang tinggi walaupun telah ada beberapa penelitian mengkaji upaya peningkatan kualitas hidup. Fungsi diastolik merupakan salah satu siklus jantung yang dikatakan dapat dideteksi lebih awal sebelum muncul manifestasi klinik sehingga lebih berpengaruh terhadap kualitas hidup dibanding fungsi sistolik. Namun ada penelitian menyatakan tidak ada perbedaan antar keduanya.Tujuan : Penelitian ini bertujuan menganalisis hubungan antara kualitas hidup dengan fungsi diastolik pasien gagal jantung kronik dengan fraksi ejeksi normalMetode : Penelitian ini adalah penelitian analitik observasional menggunakan data primer yaitu kuesioner serta data sekunder yaitu rekam medis dan data ekokardiografi. Sampel sebanyak 32 pasien yang sudah didiagnosis gagal jantung kronik dengan fraksi ejeksi normal yang memenuhi kriteria tertentu. Dari hasil ekokardiografi didapatkan nilai E/e’ sebagai indiktor fungsi diastolik. Kemudian pasien mengisi kuesioner MLHF (Minnesota Living with Heart Failure) berisi 21 pertanyaan tentang aktivitas sehari-hari mereka. Uji statistik menggunakan uji korelasi pearsonHasil : Fungsi diastolik memiliki korelasi yang tidak bermakna dengan kualitas hidup (p>0,05). Didapatkan korelasi positif sangat lemah pada dimensi fisik (r=0,044; p=0,810), dimensi umum (r=0,057; p=0,757), dimensi emosi (r=0,003; p=0,988) dan skor total MLHFQ (r=0,042; p=0,820)Kesimpulan : Tidak terdapat hubungan yang signifikan antara fungsi diastolik dengan kualitas hidup pada pasien gagal jantung kronik dengan fraksi ejeksi normal.
Prediction Score of Antegrade Chronic Total Occlusion Percutaneous Coronary Intervention Success in Dr. Kariadi Central General Hospital Semarang Pudjiastuti, Anggit; Rifqi, Sodiqur; Sofia, Sefri Noventi
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 2 (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (287.583 KB) | DOI: 10.36408/mhjcm.v7i2.514

Abstract

Background: Lesion characteristics of chronic total occlusion (CTO) are predictors of percutaneous coronary intervention (PCI) success. A prediction score consist of these predictors can help CTO-PCI operators. Various prediction score had been established but none had been established in Indonesian population. Methods: This observational cohort study was performed in patients underwent native vessel CTO-PCI in Dr.Kariadi Hospital during 2018. Target vessels, ostial lesion, blunt stump, calcification, long lesion, bending, side branch, bridging collateral, and retrograde collateral were angiographic variables proposed to be predictors of CTO-PCI success. All of the variables were quantitatively assessed by two observers. Bivariate and multivariate analysis used to identify independent predictors of CTO-PCI success and to establish a scoring model. Results: A total 200 patients underwent CTO-PCI procedures were included to this study. All of the procedures used antegrade approach. The prediction score established as follows: bending (1 point), calcification (2 point), blunt stump (3 point), long lesion (1 point), and poor retrograde collateral filling (2 point). Total score ranged from 0 to 9 with decreased probability of success from 92.3% to 0.5%. Score value ? 3 categorized as difficult lesion with higher risk to failure compared to score value <3 (OR 15.4; p<0.001). The score model had good calibration and discrimination in predict CTO-PCI success (AUC 0.88; p<0.001). Conclusion: Bending, calcification, blunt stump, long lesion, and poor retrograde collateral were predictors of CTO-PCI success. The score consist of these variables could predict antegrade CTO-PCI success. Keywords: chronic total occlusion; percutaneous coronary intervention; success; prediction score.
Kejadian Kardiovaskular Mayor di Rumah Sakit pada Pasien STEMI di Era Pandemi COVID-19 Mangkoesoebroto, Arjatya Pramadita; Herry, Yan; Sofia, Sefri Noventi; Bahrudin, Udin
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 1 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i1.852

Abstract

BACKGROUND: The Coronavirus Disease 2019 (COVID-19) pandemic has become a global burden, changing healthcare system and affecting patients with ST segment elevation myocardial infarction (STEMI). Several countries reported a decrease in hospital admission, changing management, increase total ischemic time, and major cardiovascular events (MACE) in the pandemic era. However, there is limited data especially in Indonesia. OBJECTIVE: To know the differences in admissions, characteristics, management and in-hospital MACE in STEMI patients between pre and pandemic era. METHODS: Comparative observational analytical study was done on 169 patients in the pre-pandemic (12 March 2019-11 March 2020) compared to 163 patients in the pandemic era (12 March 2020-30 September 2021) with STEMI at dr. Kariadi Semarang Hospital. Assessment of monthly admission rates, total ischaemic time, reperfusion management, COVID-19 status and MACE were carried out. RESULTS: During the COVID-19 pandemic, there was a decrease in the average admission of 14.1 to 8.6 patients per month (p<0.001), increase total ischaemic time of 8.78 (3.22-19.68) hours to 10.22 (3 .20-20.43) hours (p<0.001), decreased use of primary PCI (97.0% vs. 83.4%, p<0.001), increased fibrinolytic (1.8% vs8.6%,p=0.010) and no reperfusion (1.2%vs8.0%, p=0.007). There was a significant increase in MACE in the era of the COVID-19 pandemic (10.7%vs22.1%,p=0.008), with mortality (4.7%vs11.7%,p=0.035), stroke (1.2%vs1.8%,p=0.680), cardiogenic shock (4.1%vs11.0%, p=0.030), and acute pulmonary edema (3.6%vs10.4%,p=0.024). CONCLUSION: There was a decrease in admissions and primary PCI procedure, increase use of fibrinolytics and without reperfusion, total ischemic time prolongation, and significant increase of in-hospital MACE in STEMI patients during the COVID-19 pandemic.
Successful High-Risk Pulseless-Balloon Aortic Valvuloplasty Procedure in Uncorrected Pulmonary Atresia with Severe Congenital Aortic Stenosis and Low Left Ventricular Function Sofia, Sefri Noventi; Bahrudin, Bahrudin; Riwanto, Ignatius; Susanto, Hardhono; Soetadji, Anindita; Baskoro, Adhi Gunawan; Prawara, Ananta Sidhi; Satyagraha, Muhammad Thifan; Kurniawati, Yovie; Prakoso, Radityo
JAI (Jurnal Anestesiologi Indonesia) Vol 17, No 3 (2025): JAI (Jurnal Anestesiologi Indonesia)
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.72347

Abstract

Background: Pulmonary atresia with ventricular septal defect (PA-VSD) and severe bicuspid aortic stenosis is an uncommon condition that presents significant surgical challenges. The dual obstruction leads to chronic pressure overload, resulting in ventricular hypertrophy and decreased systolic function. A low left ventricular ejection fraction (LVEF) increases the risk of mortality during surgical interventions. Percutaneous balloon aortic valvuloplasty (PBAV) poses additional risks due to the intentional induction of pulselessness during balloon inflation. This case report aims to detail the perioperative management strategies employed during PBAV in a patient with PA-VSD, severe aortic stenosis, and low LVEF.Case: We present a 19-year-old female patient weighing 45 kg with shortness of breath and fatigue. Her oxygen saturation was measured at 90% across all extremities. Electrocardiogram (ECG) findings indicated sinus rhythm with biventricular hypertrophy and incomplete left bundle branch block (LBBB). Chest X-ray revealed cardiomegaly and pulmonary artery dilation, while echocardiography confirmed PA-VSD, severe aortic stenosis with a mean pressure gradient (mPG) of 55 mmHg, and an LVEF of 41.3%. A percutaneous pulseless-BAV was performed using a Tyshak balloon via an antegrade transvenous femoral approach under fluoroscopy and transesophageal echocardiography guidance.Discussion: Anesthesia management focused on gradual medication titration, minimizing patient movement during the procedure, and ensuring comfort due to transesophageal echocardiogram (TEE) probe insertion. A temporary pacemaker was placed in the right ventricular apex for pacing at 220 beats per minute until cardiac arrest occurred post-balloon inflation, and defibrillation successfully restored spontaneous circulation.Conclusion: This case illustrates that PBAV in uncorrected PA-VSD with severe aortic stenosis and low LVEF is feasible despite its inherent risks when conducted by a skilled team utilizing careful judgment throughout the procedure.
Co-Authors Agung Satria Winahyu Alfredo Alfredo Andreas Arie Setiawan Anindita Soetadji Ariosta Ariosta Arum Citra Melati Bahrudin Bahrudin Baskoro, Adhi Gunawan Erna Setiawati Etisa Adi Murbawani Hardhono Susanto Herry, Yan Ignatius Riwanto, Ignatius Ilham Uddin Kurniawati, Yovie Mangkoesoebroto, Arjatya Pramadita Marchilia Widistana Muhammad Ridwan Rusydi Yudanardi Nugroho, M. Arif Prawara, Ananta Sidhi Pudjiastuti, Anggit Radityo Prakoso Radiyan Meidhiyanto Risky Wijaya Utami Satyagraha, Muhammad Thifan Setiawan, I Edward Kurnia Sodiqur Rifqi Sugiri, Sugiri Tri Agrina Tsyaning, Wikan Tamara Udin Bahrudin, Udin Utami, Sulistiyati Bayu Vionika Vitasari