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All Journal Dental Journal (Majalah Kedokteran Gigi) Journal of Dentomaxillofacial Science Journal of Indonesian Dental Association JITEKGI Jurnal Ilmiah dan Teknologi Kedokteran Gigi PEDAMAS (Pengabdian Kepada Masyarakat)
Benso Sulijaya, Benso
Department Of Periodonthic, Faculty Of Dentistry, Universitas Indonesia, Jakarta, Indonesia
Humanities Dentistry Economics, Econometrics & Finance Education Energy Engineering Health Professions Law, Crime, Criminology & Criminal Justice Social Sciences

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Combination of Platelet-rich Fibrin (PRF) in Advanced Periodontitis Stage Treatment Nadhia Anindhita Harsas; Fatimah Maria Tadjoedin; Benso Sulijaya; Dimas Ilham Hutomo; Melinda Rabekka Purba; Cahyaning Wulan Sasri
Journal of Indonesian Dental Association Vol. 6 No. 2 (2023): October
Publisher : Indonesian Dental Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32793/jida.v6i2.1075

Abstract

Introduction: The treatment of advanced periodontitis has been a challenge for clinicians. Platelet-rich fibrin (PRF) is a second-generation platelet concentrate that contains various growth factorss and cytokines that promote tissue regeneration. The use of PRF in combination with other regenerative materials and techniques has been shown to be effective in the treatment of intrabony defects. This case series aims to evaluate the efficacy of PRF combinations in the regenerative treatment of patients with advanced periodontitis. Case report: Two patients diagnosed with advanced periodontitis (stage III/IV grade C) were selected for this study. After the completion of periodontal initial therapy, there were still pockets with a probing depth ≥ 5 mm (5–10 mm). Therefore, surgical interventions were planned. The first case used the combination of PRF with bone graft and guided tissue regeneration (GTR), while open flap debridement (OFD) with the addition of PRF and bone graft to create sticky bone was done in the second case. Three to five months of follow-up showed favorable outcomes, as evidenced by reductions in probing depth (PD), gains in clinical attachment level, and filling of bone defects, as well as improvements in patient comfort and rapid wound healing. Conclusion: The combination of PRF with grafting material and/or GTR has been shown to be a beneficial therapeutic approach for periodontal regenerative therapy. Platelet-rich fibrin in periodontal surgery may accelerate the tissue healing process.
Co-Authors Antonius Winoto Suhartono, Antonius Winoto Aurelle Khadeeja Rizany Cahyaning Wulan Sasri Christabella, Jesslyn Christopher Talbot Dimas Ilham Hutomo Elza Ibrahim Auerkari Ette SS. Tadjoeddin Fatimah Maria Tadjoedin Harsas, Nadhia Anindhita Hutomo, Dimas Ilham INDAH PUSPITASARI Jesslyn Christabella Lelyati, Sri Melinda Rabekka Purba Moh Firman Irwanto Muniyati Usman Nabila P. Dewi Natalina Natalina Natalina Natalina Natasha Natasha Natasha, Natasha Niniarty Zeiroeddin Djamal Puji Astuti Purba, Melinda Rabekka Rizany, Aurelle Khadeeja Sandra Olivia Kuswandani Sasri, Cahyaning Wulan Sri Lelyati C Masulili Tadjoedin, Fatimah Maria Yuniarti Soeroso