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All Journal Jurnal Teknoin Jurnal Teknik ITS IPTEK Journal of Proceedings Series IPTEK The Journal for Technology and Science Rekayasa Mesin Journal of Innovation and Applied Technology Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal Intake : Jurnal Penelitian Ilmu Teknik dan Terapan Specta Journal of Technology International Journal of Industrial Research and Applied Engineering Jurnal Abdi: Media Pengabdian Kepada Masyarakat Jurnal Kedaymas Prosiding Seminar Nasional Program Pengabdian Masyarakat Penamas: Journal of Community Service PROSIDING SEMINAR NASIONAL FISIKA (E-JOURNAL) Journal of Materials Exploration and Findings Makara Journal of Technology eProceedings of Art & Design Eduvest - Journal of Universal Studies Tintamas: Jurnal Pengabdian Indonesia Emas
Sulistijono Sulistijono
Departemen Teknik Material Dan Metalurgi, Institut Teknologi Sepuluh Nopember
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Journal : Makara Journal of Technology

 1 
Study on Antibacterial of Chitosan/Hydroxyapatite Doped Magnesium Composite as a Material for Bone Graft Applications Laksono, Andromeda Dwi; Jr., Teodoro A. Amatosa,; Sitorus, Hilda Pebrianti Octaviana; Asih, Wentika Putri Kusuma; Sulistijono, Sulistijono
Makara Journal of Technology Vol. 23, No. 3
Publisher : UI Scholars Hub

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Abstract

Hydroxyapatite (HAp) is one of the constituent minerals of bone and teeth, that has been widely used for synthesizing bone graft. Due to the limitation on properties of the hydroxyapatite, it is doping with Magnesium (HAp-Mg). The addition of Chitosan (Chi) was expected to improve the antibacterial properties of HAp-Mg. The present research aims to study the influence of Chitosan with 0, 5, 15, and 25 wt% addition on biocompatibility properties of Chi/HAp-Mg composite. HAp-Mg was synthesized using the sol-gel method; meanwhile, Chi/HAp-Mg composite was manufactured by mixing Chitosan in acetic acid, and HAp-Mg was added into the mixture. The synthesized samples were characterized using XRD and SEM. In vitro antibacterial activities of the Chi/HAp-Mg composite were evaluated against Escherichia coli bacteria. Biocompatibility analysis from antibacterial activity showed that composite with the optimal composition on the addition of 15 wt% Chitosan has the best ability in inhibiting the growth of E. coli bacteria.
Co-Authors Achly, Fariza Hafizh Adiyaksa, Muhammad Adrinanda, Noval Agung Budi Kurniawan Agung Purniawan Amrulloh, M. Farian Andiana, Rocky Andini, Risa Areliano, Samuel Ashari, Rahmat Asih, Wentika Putri Kusuma Awali, Jatmoko Azmi Mahiri Bintang Ayu Nuraeni Chusururi, Mochamad Alvan Mifta Devy Setiorini Sa’adiyah Dharma, Faridz Wira Diah Susanti Diego Pramanta Harvianto Fakhreza Abdul Farah Salsabila, Farah Faris Hizrian Maulana Faris Putra Ardiansyah Faris Putra Ardiansyah H Purwaningsih Hakim, Abdurrahman Handis Zuniandra Haniffudin Nurdiansyah Haniffudin Nurdiansyah Haniffudin Nurdiansyah Hariyati P Hariyati Purwaningsih Irbabulluba Ismail, Ika J.A. Hakim Jatmoko, Awali Jayawarsa, A.A. Ketut Jr., Teodoro A. Amatosa, Kikin Hermanto L. Noerochim Laisa, Muhammad Ikbal Laksono, Andromeda Dwi Lukman Noerochim Luthfiansyah, Candra Rizki M Rizal Pambudi M. Rizal Pambudi Mas Irfan Purbawanto Hidayat Mavindra Ramadhani Mega Ulimaz Menasita Mayantasari Menasita Menasita Mirnawati Mirnawati Moamar Al Qathafi Moh. Farid Muhammad Fachri Nafi’, Dian Naufal Gati Furqon Noor Rohmannudin, Tubagus Nurdiansyah, Haniffudin Pambudi, M Rizal R. Fajarain Rahmah, Linta Atina Ramadhani, Mavindra Ridhotullah, Aji Rinda, Sari Shaimah Rizky, Yoel Rohadi, Anggoro Rohmannudin, Tubagus N Rohmannudin, Tubagus Noor Satrianugraha, Rifqi Fernady Sidiq, Firman Sitorus, Hilda Pebrianti Octaviana Sutarsis Sutarsis Syarip Hidayat Tanjung, Rifqi Aulia Trendy Leo Pratama Tubagus N Rohmannudin Tubagus Noor R Tubagus Noor Rohmannudin, Tubagus Noor Tubagus Noor Rohmanuddin Vania Mitha Pratiwi Yunita Triana, Yunita Zaid Sulaiman