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All Journal JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Ilmu Kesehatan dan Farmasi
Dahlia Andayani
Fakultas Ilmu Kesehatan Universitas Nahdlatul Wathan Mataram
Dentistry Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health

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Influence of Phyllanthus niruri Linn. Extract Therapy on Renal and Uterus in 2% NaCl -induced Fibrotic Scarring Rodents Khairil Pahmi; Lale Syifaun Nufus; Dahlia Andayani
JIKF Vol 11 No 1 (2023): Jurnal Ilmu Kesehatan dan Farmasi
Publisher : Fakultas Ilmu Kesehatan UNW Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51673/jikf.v11i1.1747

Abstract

Background Phyllanthus niruri (english name : leafflower) extract is used in therapy of renal and uterus fibrotic scarring disease. Influence of alcohol extract of P. niruri on renal and uterus of 2% NaCl- induced fibrotic scarring rodents had been researched. Aim of Study Purpose of this research to study the influence of leafflower (Phyllanthus niruri Linn.) therapy on renal and uterus in 2% NaCl - induced fibrotic scarring rodents. Methods Wistar rodents were stimulated with 2% NaCl in drinking water to induce fibrotic scarring renal and uterus. Phyllanthus niruri extract (200 mg/kg) was given orally for 4 weeks. Matrix extracellular expression was determined by HE Staining and calculated by METAVIR fibrosis scarring score. The data of this study were analyzed by SPSS 16. Results niruri extract was able to decrease the matrix extracellular in 2% NaCl-induced rodent compared to control group (p<0.05). Conclusion P. niruri extract was able to decrease the matrix extracellular in the renal and uterus of the rodents.
Influence of Phyllanthus niruri Linn. Extract Therapy on Renal and Uterus in 2% NaCl -induced Fibrotic Scarring Rodents Khairil Pahmi; Lale Syifaun Nufus; Dahlia Andayani
JIKF Vol 11 No 1 (2023): Jurnal Ilmu Kesehatan dan Farmasi
Publisher : Fakultas Ilmu Kesehatan Universitas Nahdlatul Wathan Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51673/jikf.v11i1.1747

Abstract

Background Phyllanthus niruri (english name : leafflower) extract is used in therapy of renal and uterus fibrotic scarring disease. Influence of alcohol extract of P. niruri on renal and uterus of 2% NaCl- induced fibrotic scarring rodents had been researched. Aim of Study Purpose of this research to study the influence of leafflower (Phyllanthus niruri Linn.) therapy on renal and uterus in 2% NaCl - induced fibrotic scarring rodents. Methods Wistar rodents were stimulated with 2% NaCl in drinking water to induce fibrotic scarring renal and uterus. Phyllanthus niruri extract (200 mg/kg) was given orally for 4 weeks. Matrix extracellular expression was determined by HE Staining and calculated by METAVIR fibrosis scarring score. The data of this study were analyzed by SPSS 16. Results niruri extract was able to decrease the matrix extracellular in 2% NaCl-induced rodent compared to control group (p<0.05). Conclusion P. niruri extract was able to decrease the matrix extracellular in the renal and uterus of the rodents.
Isolasi Asam Nukleat dari Tanaman Brokoli (Brassica oleracea L.) Lale Syifaun Nufus; Dahlia Andayani; Khairil Pahmi
JIKF Vol 11 No 2 (2023): Jurnal Ilmu Kesehatan dan Farmasi
Publisher : Fakultas Ilmu Kesehatan Universitas Nahdlatul Wathan Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51673/jikf.v11i2.2038

Abstract

Asam nukleat adalah makromolekul biokimia yang kompleks,berbobot molekul tinggi,dan tersusun atas rantai nukleotida yang mengandung informasi genetik. Asam nukleat yang paling umum adalah asam deoksiribonukleat (DNA) dan asam ribonukleat (RNA). Penelitian ini dilakukan untuk mengisolasi asam nukleat dari bagian tanaman brokoli (Brassica oleracea L). Penelitian ini dilaksanakan pada hari Selasa,19 Desesmber 2023 di Laboratorium Farmasi Fakultas Ilmu Kesehatan Universitas Nahdlatul Wathan Mataram dengan metode eksploratif. Pada hasil yang didapat bahwa asam nukleat dari brokoli adalah mengapung di atas permukaan larutan.
Co-Authors Ade Irma Fitria Ningsih Andy Susbandiyah Ifada Aulia Ul Hafizah Baiq Fahrina Findawati Dede Arlita Dedy Wirawan Sukmanadi Endang Suprihartini Faridiniyati Hidayaturrohimah Intan Nurani Ikhsan Khairil Pahmi Khairil Pahmi Lale Syifaun Nufus Maruni Wiwin Diarti Maruni Wiwin Diarti Maulida Astuti Novaldi R. Abdullah Nurul Hidayati Rizki Nugrahani