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All Journal IAES International Journal of Artificial Intelligence (IJ-AI) journal of internal medicine Indonesian Journal of Applied Sciences Jurnal Keperawatan Soedirman (The Soedirman Journal of Nursing) Jurnal Surya Medika Jurnal Keperawatan Padjadjaran Jurnal Pengabdian Pada Masyarakat Jurnal Penelitian dan Pengabdian Kepada Masyarakat UNSIQ Jurnal Aisyah : Jurnal Ilmu Kesehatan Medical and Health Journal

Eman Sutrisna

Universitas Jenderal Soedirman

Author-ID : 397478

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Education Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary Other

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RANDOMIZED CLINICAL TRIAL OF OMEPRAZOLE AND RANITIDINE USING INDONESIAN TRANSLATED NEPEAN DYSPEPSIA INDEX Arinton, I Gede; Samudro, Pugud; Sutrisna, Eman; IDN, Wibawa
journal of internal medicine Vol. 7, No. 3 September 2006
Publisher : journal of internal medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (93.923 KB)

In patients with dyspepsia, a common initial management strategy in primary care is to prescribe a course ofempiric antisecretory therapy. Ranitidin and omeprazole as antisecretory agents have been proven effective fortreatment of dyspepsia. This research was aimed to evaluate the effect of omeprazole and ranitidine by using NepeanDyspepsia Index (NDI) which was translated and validated in Indonesian language. Fifty healthy persons were askedto complete the Indonesia translated NDI(NDII) and Short Form(SF)- 36, which was previously validated. Cronbach' salpha and test-retest were performed for reliability analysis. Spearman's rank correlation was used to assess validity. P-value <0.03 was considered statistically significant. The results concluded that NDIl can be used in dyspepsia patientswho understand Indonesian language. The number of 104 subjects with a clinical diagnosis of dyspepsia according tothe inclusion and exclusion criteria were recruited and randomized to receive ranitidine 150 mg twice daily andomeprazole 20 mg twice daily. Symptoms of dyspepsia were evaluated by using NDIl at baseline one week aftertreatment. The outcomes of omeprazole and ranitidine were evaluated by comparing improved NDIl score in 5domains (tension, activities, eating/drinking, knowledge/control and work/study). The mean of age in the subjects was47 years old that consisted of 36% male. After one week treatment, the NDIl dyspepsia patients score in omeprazoletreated group was not significantly different from that in ranitidine treated group. The effect of omeprazole was notbetter than ranitidine when it was given as empirical treatment for dyspepsia patients in primary care.

Efficacy of Listening to Murattal in Reducing the Pain Experienced by ICU Patients Purnawan, Iwan; Hidayat, Arif Imam; Sutrisna, Eman; Alivian, Galih Noor; Wirakhmi, Ikit Netra
Jurnal Keperawatan Soedirman Vol 16, No 3 (2021)
Publisher : Jurusan Keperawatan FIKES UNSOED

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jks.2021.16.3.1567

Background: Pain is one of the main problems in patients with ICU. Inadequate handling can cause adverse effects such as unstable hemodynamics, trigger stress, and thus hinder the healing process. Non-pharmacological intervention is needed to help manage pain in patients with ICU. Purpose: This study aims to identify the effect of murottal listening to pain in ICU patients. Methods: This is a quasi-experiment with pre-test and post-test with control group design. The sampling technique was simple random sampling, consisting of 40 respondents divided into two groups. The Critical Pain Observation Tool (CPOT) is used to measure pain. Statistics using a paired t-test, Wilcoxon-test, and Mann Whitney. Results: Significant decreases in pain scores were observed in treatment groups of 4, 5 to 4,0; p = 0,013. In the control group, there was a significant decrease in pain scores from 4,8 to 4,3; p = 0,001. There was no significant difference between the median decrease in pain in the intervention group (0.001 (-1-2.0) and the control group (0.001 (0.001-1.0)) with p = 0.242. Conclusion: Murottal listening does not have a significant effect on pain in patients of ICU.

Uji Efek Larvasida Ekstrak Daun Gamal (Gliricida sepium) terhadap Larva Nyamuk Aedes aegypti Rundito Rundito; Dody Novrial; Eman Sutrisna
Jurnal Surya Medika (JSM) Vol 7 No 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i2.2454

Gamal leaves (Gliricidia sepium) well known as liquid organic fertilizer, are also known to have potential as vegetable larvicides because there are flavonoids, triterpenoids, coumarin, coumaric acid, mitotic acid, and stigmastanol glucoside which can be identified and isolated from various parts from Gamal. The aim of this study was to examine the larvicidal effect of Gamal (G. sepium) leaf extract against larvae of Aedes aegypti mosquitoes. The study was conducted using an experimental design with a posttest-only control group design and a completely randomized design consisting of 6 treatment groups. Two groups as control (positive and negative control), while 4 other groups received treatment of Gamal leaf extract (G. sepium) at doses of 50 ppm (P1), 150 ppm (P2), 250 ppm (P3), and 350 ppm (P4). There was no mortality of larvae Aedes aegypti from pure lines after giving Gamal leaf extract, but mortality only occurred in Aedes aegypti larvae positive control group originating from the field. Unknown LC50 and LC90. A total of 13 (52%) Ae. aegypti strain classified as tolerant, while as many as 19 (76%) larvae of Aedes aegypti originating from the field are classified as resistant.

PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN SENDOK (PLANTAGO MAYOR L.) TERHADAP PENGHAMBATAN OVEREKSPRESI GEN REGENERATING-1, PENINGKATAN KADAR CASPASE-3 DAN GAMBARAN HISTOPATOLOGI JARINGAN MUKOSA LAMBUNG TIKUS MODEL HIPERGASTRINEMIA - The Effect of Ethanol Extracts of Plantain (Plantago Mayor L.) on Inhibition of Over-expression of Regenerating-1 Gene, Increasing Caspase-3 Level and Histopatologic Feature of Gastric Mucosa of Hypergastrinemic Rat Model Eman Sutrisna Eman Sutrisna; Ani M Maskoen; Muchtan Sujatno; Herri S. Sastramihardja
Indonesian Journal of Applied Sciences Vol 4, No 1 (2014)
Publisher : Universitas Padjadjaran

AbstrakEkstrak etanol daun sendok mengandung banyak zat aktif, termasuk triterpenoid dan flavonoid yang memiliki efek anti proliferatif, anti angiogenesis dan menginduksi apoptosis sel kanker. Hipergastrinemia dapat menginduksi over-ekspresi Gen Regenerating 1, menekan produksi Caspase 3 dan perubahan histopatologi jaringan mukosa lambung. Penelitian ini menganalisis pengaruh pemberian ekstrak etanol daun sendok terhadap penghambatan over ekspresi gen Regenerating 1, peningkatan kadar Caspase 3 dan perubahan histopatologi jaringan mukosa lambung tikus model hipergastrinemia. Penelitian ini dilakukan secara eksperimental dengan post test only with control group design. 28 tikus putih dibagi menjadi empat kelompok. Kelompok I (kontrol) diberi Omeprazol dosis 8mg/200gBB tikus/hari, Ciprofibrate dosis 12,5mg/200gBB tikus/hari dan 3 kelompok studi (Kelompok II, III dan IV diberi Omepr azol dosis 8mg/200gBB tikus/hari, Ciprofibrate dosis 12,5mg/200gBB tikus/hari dan ektrak etanol daun sendok masing-masing dosis 50mg, 100 mg dan 200mg per 200gBB tikus/hari). Semua hewan coba dikorbankan dibawah pengaruh anestesi setelah perlakuan selama 2 bulan. Sampel darah dan gaster hewan coba diambil untuk pemeriksaan kadar gastrin dan Caspase 3 dengan metode ELISA, ekspresi Gen Regenerating1 dengan RT-PCR serta histopatologi jaringan mukosa lambung. Kadar gastrin hewan coba meningkat 3-4 kali kadar gastrin normal (>169 pg/mL). Rerata ekspresi Gen Regenerating 1 terendah terjadi pada Kelompok III (1,226±0,108) Analisis statistik menunjukkan terdapat perbedaan ekspresi Gen Regenerating 1 secara bermakna antara Kelompok III dengan kontrol (nilai p= 0,016;IK 95%). Rerata kadar Caspase 3 tertinggi terdapat pada IV (0,603±0,172ng/mL). Analisis statistik menunjukkan terdapat perbedaan kadar Caspase 3 secara bermakna antara kelompok IV dan Kelompok lainnya (nilai p <0,05;IK 95%). Gambaran histopatologi mukosa lambung menunjukan atropi dan tidak terdapat perbedaan ketebalan jaringan mukosa lambung secara bermakna diantara kelompok penelitian (nilai p=0,092; IK95%). Pemberian ekstrak etanol daun sendok mencegah over-ekspresi Gen Regenerating 1 dengan dosis 100mg/200gBB/hari, meningkatkan kadar Caspase 3 dengan dosis 200mg/200gBB/hari tetapi pada dosis penelitian yang digunakan tidak dapat menghambat perubahan histopatologi jaringan mukosa lambung tikus model hipergastrinemiaKata Kunci: Ekstrak etanol daun sendok, Over ekspresi Gen Regenerating 1, Caspase 3, Histopatologi mukosa lambung, Model HipergastrinemiaAbstractPlantago major L has a lot of active substances, including triterpenoid and flavonoid that show anti proliferative effect, anti angiogenesis and induce cancer cells apoptosis. Hypergastrinemia able to induce overexpression of Regenerating 1 gene, inhibit activation of caspases include Caspase 3 and cause histopathologic alteration of gastric mucosal tissues. This study was to evaluate the effect of Plantago major L extract.on inhibition of Regenerating 1 gene overexpression, increasing of Caspase-3 level and histopathologic alteration of gastric mucosal tissues on hypergastrinemic rat (Rattus norvegicus) model. By experimental study and post test only with control group design, 28 of rats was divided in to 4 groups. Group I as a negative control was given Omeprazole 8mg/200gbw rat and Ciprofibrate dose 12,5 mg/200gbw rat/day and aquadest per oral. Group II was given Omeprazole 8mg/200gbw rat and Ciprofibrate dose 12,5 mg/200gbw rat/day and Plantago major L. extract 50mg/200gbw rat/day per oral. Group III was given Omeprazole 8mg/200gbw rat and Ciprofibrate dose 12,5 mg/200gbw rat/day and Plantago major L. extract 100mg/200gbw rat/day per oral. Group IV was given Omeprazole 8mg/200gbw rat and Ciprofibrate dose 12,5 mg/200gbw rat/day and Plan tago major L. extract 200mg/200gbw rat/day per oral. They were killed after 2 month intervention under anaesthetic. Blood sample and gaster organs were collected for measurement of gastrin and caspase 3 level by using ELISA method, expression of Regenerating 1 gene by RT-PCR and histopatological examination of gastric mucosal tissues. There were increasing of gastrin level of rats up to 3-4 times fold compared to normal level and to indicate hypergastrinemic condition. The lowest average of Regenerating 1 gene expression was found on Group III (1,226±0,108). Statistic analysis show that there were significantly difference of Regenerating 1 gene expression between group III and Control (p= 0,016; 95%CI) The highest average of Caspase-3 level was found on Group IV(0,603±0,172ng/mL) and there were significantly difference of caspase-3 level between group IV and the other Groups (p< 0,05; 95%CI). There were atrophic process on gastric mucosal tissue but there were not significantly difference of gastric mucosal thickness between group (p= 0,092; 95%CI). This study can be concluded that administration of Plantago major L extract able to inhibit overexpression of Regenerating 1 gene by dose 100mg/200gbw rat/day, to increase Caspase 3 level by dose 200mg/200gbw rat/day but can not to inhibit histopathologic alteration of gastric mucosal tissues by using all of the doses. Keyword: Ethanol extract of Plantago major L, Regenerating 1 gene overexpression, Caspase 3, gastric mucosal histopatology, Hypergastrinemia model

Pemberdayaan Kader Posyandu Lansia Untuk Pencegahan Hipertensi dan Komplikasinya di Purwokerto Yunita Sari; Made Sumarwati; Eman Sutrisna
Jurnal Pengabdian Pada Masyarakat Vol 3 No 1 (2018)
Publisher : Universitas Mathla'ul Anwar Banten

EMPOWERMENT OF ELDERLY POSYANDU CADRES FOR PREVENTING HYPERTENSION AND ITS COMPLICATION IN PURWOKERTO. The highest prevalence of degenerative diseases in Banyumas regency is hypertension. The prevention of hypertension in elderly could be done by Elderly Posyandu. However, there are many problems which occur in Elderly Posyandu of Soka Nirmala III and Sejahtera II in preventing hypertension and its complication, such as the limitation of materials for blood pressure measurement, lack of knowledge for hypertension management, lack of knowledge about self-treatment for reducing blood pressure. The purposes of this programme were to give kits for hypertension measurement to elderly posyandu, to conduct training of hypertension prevention, training about diet management, training about elderly exercise, training about self-treatment for reducing blood pressure. This community service was done through health education, training, and simulation. This community service could improve the knowledge of cadres and elderly in managing hypertension, improve knowledge in conducting exercise for reducing hypertension, improve knowledge in diet management, and improve the knowledge about self-treatment for reducing hypertension. It is expected that the prevalence of hypertension and its complication could be reduced and the quality of life of elderly could be improved.

UNRAVELLING THE IMPACT OF RELIGIOUS THERAPY ON STRESS BIOMARKERS IN ICU PATIENTS - A TRUE EXPERIMENTAL STUDY Iwan Purnawan; Arif Imam Hidayat; Sidik Awaludin; Galih Noor Alivian; Eman Sutrisna; Ikit Netra Wirakhmi
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 8, No 3: September 2023
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v8i3.2243

Elevated stress biomarkers, such as cortisol, in response to stress conditions, can impede the healing process, prolong hospitalization, and escalate healthcare costs. This research examines the influence of religious therapy on cortisol levels in Intensive Care Unit (ICU) patients. Employing a true experimental design, 40 ICU patients were randomly assigned to the intervention or control group, comprising 20 participants each. Salivary cortisol samples were collected before and after the intervention and analyzed using the ASSAY method.The intervention group received religious therapy consisting of 15-minute sessions of listening to Quranic recitations, while the control group received no treatment. Statistical analysis involved an independent t-test to assess mean differences in cortisol level reduction between the two groups. Homogeneity testing confirmed that both groups had similar demographic characteristics regarding gender and age (p 0.05).The results showed a significant difference in mean cortisol level reduction between the intervention group (16.3 + 25.3 ng/ml) and the control group (-0.4 + 18.2 ng/ml) (p = 0.021). Additionally, Cohen's d-test indicated a substantial effect size of 0.71, highlighting the notable impact of religious therapy on cortisol level reduction. In conclusion, religious therapy effectively reduced cortisol levels among critically ill patients in the ICU.

The effect of features combination on coloscopy images of cervical cancer using the support vector machine method Supriyanti, Retno; Aryanto, Andreas S.; Akbar, Mohammad Irham; Sutrisna, Eman; Alqaaf, Muhammad
IAES International Journal of Artificial Intelligence (IJ-AI) Vol 13, No 3: September 2024
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijai.v13.i3.pp2614-2622

Cervical cancer is cancer that grows in cells in the cervix. This cancer generally develops slowly and only shows symptoms when it has entered an advanced stage. Therefore, it is crucial to detect cervical cancer early before serious complications arise. One way to detect cervical cancer early is to use colposcopy, which is to look closely at the condition of the cervix to find changes in cells in the cervix that have the potential to become cancer. However, this method requires the expertise of an obstetrician. This research proposes the use of image processing techniques to create automatic early detection of cervical cancer based on coloscopy images. In this paper, we will discuss image selection using an approach in the form of comparing the weights of feature vectors and then using a data distribution threshold, features that are not too influential can be eliminated. Image classification uses the Support Vector Machine (SVM) method, which makes it possible to distinguish normal images from abnormal images. Classification with feature selection and merging results can improve the consistency of SVM model performance evenly across all four SVM kernels.

ANTIBACTERIAL ACTIVITY OF EGGPLANT ETHYL ACETATE EXTRACT (Solanum melongena L.) AGAINST Escherichia coli Handayani, Mira Syafira; Setiawati, Setiawati; Krisniawati, Nia; Sutrisna, Eman
Medical and Health Journal Vol 2 No 2 (2023): February
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Terong ungu mengandung senyawa metanol, flavonoid, saponin dan tanin yang berpotensi sebagai antibakteri. Escherichia coli merupakan salah satu kuman penyebab berbagai macam infeksi dan saat ini banyak dilaporkan telah mengalami resistensi terhadap sejumlah antibiotik onvensional. Tujuan penelitian ini untuk mengeksplorasi aktivitas antibakteri dari ekstrak etil asetat terong ungu terhadap bakteri Escherichia coli (E. coli). Penelitian ini merupakan penelitian eksperimental dengan metode mikrodilusi untuk menentukan nilai konsentrasi hambat minimal (KHM) dan metode spread-plate untuk menentukan konsentrasi bunuh minimal (KBM). Penelitian ini menggunakan berbagai dosis ekstrak etil asetat terong ungu (5-40 mg/mL) sebagai kelompok perlakuan dan kelompok kontrol yang tidak diberikan ekstrak etil asetat terong ungu. Ekstrak etil asetat terong ungu mempunyai nilai KHM sebesar 20 mg/mL dan nilai KBM sebesar 20mg/mL. Semakin tinggi konsentrasi ekstrak etil asetat terong ungu, semakin besar pula persentase hambatan ekstrak etil asetat terong ungu terhadap bakteri E. coli. Ekstrak etil asetat terong ungu mempunyai potensi sebagai antibakteri terhadap E. coli

Pemberdayaan kader posyandu lansia untuk meningkatkan kemandirian keluarga dalam perawatan pasca stroke Upoyo, Arif Setyo; Sri Rejeki, Dwi Sarwani; Sutrisna, Eman
Jurnal Penelitian dan Pengabdian Kepada Masyarakat UNSIQ Vol 12 No 1 (2025): Januari
Publisher : Lembaga Penelitian, Penerbitan dan Pengabdian Masyarakat (LP3M) UNSIQ

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32699/ppkm.v12i1.7991

Introduction: The problems that post-stroke patients still face after being hospitalized are weakness in one side of the body (hemiparesis), speech disorders (dysarthria/aphasia), difficulty swallowing (dysphagia) and psychological disorders such as post-stroke depression and the risk of recurrent attacks. The purpose of the service is to improve the knowledge and skills of partners about: early detection of stroke, post-stroke care, post-stroke physical exercise, post-stroke speech therapy, post-stroke swallowing therapy, post-stroke psychological management. The method carried out is training with lectures, discussions and demonstrations, the media used are modules and videos. The participants were elderly Posyandu cadres and families who took care of family members after a stroke totaling 19 people. The success of the training was evaluated by comparing pre and posttest scores and assessing the participants' ability to demonstrate the actions taught. The results obtained by the knowledge of early detection, psychological management and post-stroke care of participants were 100% improved. Skills about early detection of stroke, ROM exercises, swallowing exercises and speech therapy 89.47% of participants improved. Conclusion: The training is effective in improving the knowledge and skills of cadres and families in caring for post-stroke patients. Key word: post-stroke, training, cadres, family, care

Motivation and self-efficacy as key factors influencing self-care in hypertensive adults: A cross-sectional study in Indonesia Upoyo, Arif Setyo; Sari, Yunita; Sutrisna, Eman; Taufik, Agis; Han, Hae-Ra
Jurnal Keperawatan Padjadjaran Vol. 13 No. 2 (2025): Jurnal Keperawatan Padjadjaran
Publisher : Faculty of Nursing Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkp.v13i2.2609

Introduction: Self-care is crucial for enhancing life quality and and preventing cardiovascular, renal, and vascular complications in individuals with hypertension. However, self-care among patient’s hypertension remains suboptimal. Our research aimed to identify the determinants of self-care practice among hypertensive patients in Indonesia. Methods: A survey that was cross-sectional. It carried out among 209 adults with hypertension attending community health centers in Central Java, Indonesia. Self-care behaviors, motivation, self-efficacy, and knowledge were assessed using the validated Hypertension Self-Care Profile (HBP-SCP) and Hypertension Knowledge-Level Scale (HKLS). Chi-square and multivariable logistic regression tests were used to evaluate the data. Results: Bivariate analysis revealed significant correlation between self-care behavior and motivation (p<0.001), self-efficacy (p<0.001), and history of hypertension in the family (p=0.018). No significant associations were observed for age, gender, education, occupation, body mass index, blood pressure, or knowledge (all p>0.05). Multivariable analysis demonstrated that motivation (OR=2.22, 95% CI=1.10–4.45, p=0.025) and self-efficacy (OR=7.84, 95% CI=3.99–15.39, p<0.001) were independent determinants of good self-care. Conclusions: Motivation and self-efficacy are key determinants of hypertension self-care behaviors among Indonesian adults. Interventions should prioritize strengthening motivation and building self-efficacy through motivational interviewing, skills training, and structured follow-up by nurses and other healthcare professionals.

Co-Authors Agis Taufik Akbar, Mohammad Irham Alivian, Galih Noor Alqaaf, Muhammad Ani M Maskoen Ani M Maskoen, Ani M Annisa A Fitriani, Annisa A Arif Imam Hidayat Arif Setyo Upoyo Aryanto, Andreas S. Dody Novrial, Dody Dwi Sarwani Sri Rejeki Galih Noor Alivian Han, Hae-Ra Handayani, Mira Syafira Herri S. Sastramihardja I Gede Arinton Islimsyaf A Salim, Islimsyaf A Iwan Purnawan Iwan Purnawan Krisniawati, Nia Made Sumarwati MUCHTAN SUJATNO Pugud Samudro Retno Supriyanti Rundito Rundito Setiawati Setiawati Sidik Awaludin Wibawa IDN Wirakhmi, Ikit Netra Yunita Sari Yunita Sari

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