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All Journal Journal of Dentistry Indonesia ODONTO Dental Journal Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry MDJ (Makassar Dental Journal) Indonesian Journal of Prosthodontics Odonto dental journal
Ira Tanti
Department Of Prosthodontics, Faculty Of Dentistry, Universitas Indonesia, Jakarta 10430
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Comparison of formant scores between complete denture users and subjects with complete dentition: a preliminary study Andryas, Ika; Syarfina, Tengku; Tanti, Ira; Hong, Guang; Kusdhany, Lindawati S.
Padjadjaran Journal of Dentistry Vol 37, No 1 (2025): March 2025
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol37no1.59201

Abstract

Introduction: Edentulism impairs the ability to chew, eat, and speak properly. Dentures, which aim to address this issue, are also believed to contribute to a decrease in the peak intensity value and spectral width of sound formants. Formants refer to the air within the vocal tract that is set in vibration by the vocal fold's action. This study aims to observe changes in formant values between complete denture users and participants with complete dentition. Methods: This preliminary study recruited six voluntary participants, divided into two groups. The first group consisted of subjects with complete dentition, while the second group comprised individuals wearing complete dentures on both arches. All participants introduced themselves, and their speech was recorded using PRAAT® software. For the second group, recordings were made both with and without dentures. Statistical analysis was performed using one-way ANOVA. Results: Significant differences in formant scores were observed across all groups. Post hoc tests revealed a significant difference in formant scores between completely edentulous subjects without dentures and the complete dentition group; Conclusion: Correcting speech defects is the third main objective in fabricating denture prostheses. Enhancing the phonetically beneficial construction of denture quality improves psychosocial parameters, including quality of life and socialization abilities, and accelerates successful Prosthodontic treatment. The findings indicate that the format score of a person with a complete denture is not substantially different from that of an individual with complete dentition. Conversely, individuals who have lost their complete dentures and not using complete denture may exhibit significant differences in formant score.
The Potency of miRNA 221-3p as a Molecular Biomarker Of Temporomandibular Disoder: Narrative Review Rintoko, Bimo; Tanti, Ira; Bachtiar, Endang Winiati; Bachtiar, Boy Muchlis; Prihastari, Lisa
Odonto : Dental Journal Vol 12, No 3 (2025): December 2025
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.12.3.241-250

Abstract

United States. The trigeminal nerve might be the source of orof facial pain. Pain can be difficult to diagnose and treat due to the variability of pain complaints. miRNA 221-3p could be a potential biomarker for pain. Genetic polymorphisms and genetic mutations can lead to changes in the activity of inflammatory mediators, sex hormones, matrix-degrading enzymes, and the immune system, which affect bone remodeling homeostasis in the temporomandibular joint.Method: Scientific databases PubMed, Scopus, and Google Scholar were searched for articles published between 2013 and 2023 in order to conduct the study. 168 carefully selected publications providing information on possible biomarkers, particularly miRNA 221-3p, were included in the review of the literatureResult: Genetic polymorphisms and genetic mutations can lead to changes in the activity of inflammatory mediators, sex hormones, matrix-degrading enzymes, and the immune system, which affect bone remodeling homeostasis in the temporomandibular joint. In addition, activity changes were also observed in neurotransmitters and pain receptors, which resulted in relatively high pain sensitivity. Thus, this condition also increases susceptibility to TMD. Genetic analysis and biomarkers of temporomandibular disorders may improve sensitivity and specificity measures in diagnosing and treating patients with TMDConclusion: As a multifactorial disease, genetic factors are risk factors for TMD. Genetic polymorphisms and genetic mutations can lead to changes in the activity of inflammatory mediators, sex hormones, matrix-degrading enzymes, and the immune system, which affect bone remodeling homeostasis in the TMD
The Potency of miRNA 221-3p as a Molecular Biomarker Of Temporomandibular Disoder: Narrative Review Rintoko, Bimo; Tanti, Ira; Bachtiar, Endang Winiati; Bachtiar, Boy Muchlis; Prihastari, Lisa
Odonto : Dental Journal Vol 12, No 3 (2025): December 2025
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.12.3.241-250

Abstract

United States. The trigeminal nerve might be the source of orof facial pain. Pain can be difficult to diagnose and treat due to the variability of pain complaints. miRNA 221-3p could be a potential biomarker for pain. Genetic polymorphisms and genetic mutations can lead to changes in the activity of inflammatory mediators, sex hormones, matrix-degrading enzymes, and the immune system, which affect bone remodeling homeostasis in the temporomandibular joint.Method: Scientific databases PubMed, Scopus, and Google Scholar were searched for articles published between 2013 and 2023 in order to conduct the study. 168 carefully selected publications providing information on possible biomarkers, particularly miRNA 221-3p, were included in the review of the literatureResult: Genetic polymorphisms and genetic mutations can lead to changes in the activity of inflammatory mediators, sex hormones, matrix-degrading enzymes, and the immune system, which affect bone remodeling homeostasis in the temporomandibular joint. In addition, activity changes were also observed in neurotransmitters and pain receptors, which resulted in relatively high pain sensitivity. Thus, this condition also increases susceptibility to TMD. Genetic analysis and biomarkers of temporomandibular disorders may improve sensitivity and specificity measures in diagnosing and treating patients with TMDConclusion: As a multifactorial disease, genetic factors are risk factors for TMD. Genetic polymorphisms and genetic mutations can lead to changes in the activity of inflammatory mediators, sex hormones, matrix-degrading enzymes, and the immune system, which affect bone remodeling homeostasis in the TMD
Co-Authors Achmad Riwandy Amalina, Fadhillah Nur Ariyanti Rezeki Astari Larasati Boy Bachtiar Dhani Ayu Andini Endang W Bachtiar Geraldine Ria Adrianne Guang Hong, Guang Happysari, Septyana Ika Andryas Krisna, Yohanes Paulus Laura Susanti Himawan Laura Susanti Himawan Laura Susanti Himawan, Laura Susanti Lindawati S. Kusdhany Lisa Prihastari, Lisa Maria Purbiati Maxwell, David Nina Ariani Pinta Marito Retno Pontjowulandari Rintoko, Bimo Saputra, Cindy Maura Soenawan Soenawan Suhandi Sidjaja Suria, Nia Ayu Ismaniati Tengku Syarfina Tjang, Steven Alexander