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All Journal Zenit Global Medical and Health Communication Journal of Medicine and Health Jurnal Medika Malahayati Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Jurnal Ilmiah Kesehatan
Fen Tih
Universitas Kristen Maranatha, Bandung
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Effect of Chewing Xylitol Gum on Salivary Volume and Acidity Angwarmase, Alfonsa; Tih, Fen; Hidayat, Meilinah
Journal of Medicine and Health Vol 1, No 5 (2017)
Publisher : Maranatha Christian University

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Abstract

Dental caries or tooth decay is a result of the production of acid from fermentation ofbacteria that destroy tooth tissue. It can be prevented by maintaining the stability of salivaryvolume and acidity. Chewing xylitol gum is beneficial for increasing salivary volume andacidity. The aim of the study is to determine the effect of chewing xylitol gum on salivary volumeand acidity. The study is a quasi experiment conducted to 30 males aged between 17-25 yearsold. Pre and post treatment’s salivary volume are measured with measuring cup. Pre and posttreatment’s salivary acidity are measured using a pHmeter with 0,1 accuracy. Data areanalyzed with paired “t” test (a = 0,05). Average salivary volume after chewing xylitol gumincreased very significantly from 0,26 mL to 13,37mL (p=0,000). Average salivary acidity afterchewing xylitol gum increased very significantyly from 6,47 to 7,36(p=0,000). The researchconcludes that chewing xylitol gum increases salivary volume and acidity.Keywords : dental caries, xylitol, salivary volume, salivary acidity
Cytotoxic Activity of Red Fruit (Pandanus conoideus Lam.) Oil and Its Effect On Cyclooxygenase-2 Gene Expression in Raji Cells Tih, Fen
Journal of Medicine and Health Vol 1, No 3 (2016)
Publisher : Maranatha Christian University

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Abstract

The number of cancer patient is increasing, while a really effective therapy has not yet been discovered. One concept of carcinogenesis is the relation between chronic inflammation and cancer. Cyclooxygenase-2 (COX-2) has a carcinogenic effect in inflamed and malignant tissues. Red Fruit contains carotenoid that can suppress COX-2 gene expression and tocopherol, which is a potent inhibitor of  COX-2.  The purpose of this study is to determine cytotoxic activity of Red Fruit oil and its effect on COX-2 gene expression. The experiment used 5 dosages of Red Fruit, 100, 200, 300, 400, and 500 µg/mL, exposed to Raji cells. However, unexposed Raji cells were used as control. Cytotoxic activities were evaluated by MTT Assay, while Lethal Concentration50 (LC50) was determined through regression-correlation analysis. Red Fruit oil effect on COX-2 gene expression was evaluated by Reversed Transcriptase Chain Reaction (RT-PCR) method and electrophoresis. Electrophoresis bands were analyzed by Scion Image for Windows. Optical Integrated Density (OID) of unexposed and exposed groups were statistically analyzed with one way Analysis of Variance (ANOVA), followed by Duncan test with α=0.05. The results showed that Red Fruit had a cytotoxic activity on Raji cells with LC50 of331.42 µg/mL. Red Fruit suppressed COX-2 gene expression with an effective dosage obtained at 500 µg/mL.          Keywords: red fruit, cytotoxicity, cox-2 gene expression, raji cells
Black Chocolate Consumption Reduces Subjective Symptoms in 18-22 Years Old Females with Premenstrual Syndrome Nurazizah, Eliza; Tih, Fen; Suwindere, Winny
Journal of Medicine and Health Vol 1, No 1 (2015)
Publisher : Maranatha Christian University

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Abstract

Menstruation is the release of the endometrium with bleeding every month, except during pregnancy. Before or during menstruation, a woman may experience stiffness or abdominal cramps, mood fluctuations and other physical and psychological disorders, which is termed as premenstrual syndrome (PMS). The aim of this research is to observe and value the effect of dark chocolate on clinical symptoms of PMS. This research is an experimental prospective, using experimental design with one group pre and post test. Subjects were 30 women aged 18-22 years. Every day for 2 weeks before menstruation period, subjects took 20 gram of dark chocolate, then were asked to answer questionaire. The data measured is the score as well as individual PMS symptoms before and after eating dark chocolate, was analyzed using a nonparametric Wilcoxon test, followed by McNemar chi square with α=0.05. A highly significant decrease was found in anxiety symptoms, whereas statistically significant reduction was found in fatigue or feeling tired, cramps abdominal, bloating, diarrhea, headache, back pain, change in appetite, muscle or joint pain, and problems in concentration. But the symptom of acne complaint was increased from 73.3% to 76.7%. Consumption of dark chocolate reduces premenstrual syndrome scores on women aged 18-22 years. Keywords: dark chocolate, premenstrual syndrome
Effect of Methanolic Extract in Ointment and Powder of Kalanchoe Pinnata (Lamk) Leaf in Ointment towards Incision Wound Healing in Mice Suprapto, Adi K; Tih, Fen; Evacuasiany, Endang
Journal of Medicine and Health Vol 1, No 1 (2015)
Publisher : Maranatha Christian University

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Abstract

Wound is a very common thing that can happen to all people around the world. The purpose of this study is to investigate the effect of methanolic extract and powder of Kalanchoe pinnata (Lamk) leaf in ointment. The methodology is laboratoric experimental design. Six groups of mice (n=30) were incised for 8 mm and treated with different treatment: methanolic extract of Kalanchoe pinnata (Lamk) leaves in ointment (SEMDSB) 10%, SEMDSB 20%, Kalanchoe pinnata (Lamk) leaves powder in ointment (SSDSB) 10%, SSDSB 20%, vaseline album (ointment) as negative control, and povidone iodine ointment as positive control. Examination is carried out by measuring the width of wounds in mice every day until the wound interlocked. Data analysis used one way ANOVA continued by Tukey HSD with α=0,05. The result showed the average time for wound healing (in days) are: SEMDSB 10% (7.2), SEMDSB 20% (6.6), SSDSB 10% (8.8), SSDSB 20% (7.6), negative control (10.6), and positive control (7.8). SEMDSB 10%, SEMDSB 20%, and SSDSB 20% showed highly significant difference (p = 0,000) and SSDSB 10% showed significant difference (p=0,021) when compared to negative control. As conclusion, methanolic extract  and powder of Kalanchoe pinnata (Lamk) leaves in ointment can accelerate wound healing time. Keywords: ointment, Kalanchoe pinnata (Lamk), wound healing, mice
Kandungan Logam Timbal, Besi, dan Tembaga dalam Air Minum Isi Ulang di Kota Bandung Tih, Fen; Kusumawardani, Indah; Estevania, Margaret Yosephine; Simanjuntak, Ezra Artur Stefano
Zenit Vol 4, No 3 (2015)
Publisher : Zenit

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Abstract

Water necessity is mostly fulfilled from drinking water, which should be in adequate quantity and quality. One of the sources of drinking water is refilled drinking water depots. As stated in health department rules (Permenkes RI Nomor 492/Menkes/Per/IV/2010), heavy metal content in drinking water cannot exceed the permitted level, including lead, iron and copper. The aim of this research is to determine whether there is over permitted level of lead, iron and copper content in refilled drinking water from depots throughout Bandung. This research is a descriptive survey with a cross sectional design. Thirty depots have been randomly selected from 150 registered depots in Bandung. Heavy metal contents are analyzed quantitatively with spectrophotometric method. The result shows that 30 samples do not have lead, iron and copper level content above the permitted level. However, some samples show almost a maximal level of heavy metal content which could influence health when consumed in the long termKeywords: refilled drinking water, lead, iron, copper
Effect of Chewing Xylitol Gum on Salivary Volume and Acidity Angwarmase, Alfonsa; Tih, Fen; Hidayat, Meilinah
Journal of Medicine and Health Vol. 1 No. 5 (2017)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (286.827 KB) | DOI: 10.28932/jmh.v1i5.542

Abstract

Dental caries or tooth decay is a result of the production of acid from fermentation ofbacteria that destroy tooth tissue. It can be prevented by maintaining the stability of salivaryvolume and acidity. Chewing xylitol gum is beneficial for increasing salivary volume andacidity. The aim of the study is to determine the effect of chewing xylitol gum on salivary volumeand acidity. The study is a quasi experiment conducted to 30 males aged between 17-25 yearsold. Pre and post treatment’s salivary volume are measured with measuring cup. Pre and posttreatment’s salivary acidity are measured using a pHmeter with 0,1 accuracy. Data areanalyzed with paired “t” test (a = 0,05). Average salivary volume after chewing xylitol gumincreased very significantly from 0,26 mL to 13,37mL (p=0,000). Average salivary acidity afterchewing xylitol gum increased very significantyly from 6,47 to 7,36(p=0,000). The researchconcludes that chewing xylitol gum increases salivary volume and acidity.Keywords : dental caries, xylitol, salivary volume, salivary acidity
Efek Konsumsi Air Kelapa (Cocos nucifera) terhadap Ketahanan Berolahraga Selama Latihan Lari pada Laki-laki Dewasa Bukan Atlet Fen Tih Fen Tih; Harijadi Pramono; Stella Tinia Hasianna; Ersalina Tresnawati Naryanto; Albertus Gani Haryono; Oliver Rachman
Global Medical & Health Communication (GMHC) Vol 5, No 1 (2017)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (150.998 KB) | DOI: 10.29313/gmhc.v5i1.1966

Abstract

Ketahanan berolahraga menunjang latihan fisik yang optimal untuk meningkatkan derajat kesehatan dan kebugaran jasmani. Penurunan kapasitas ketahanan olahraga disebabkan oleh dehidrasi dan penurunan karbohidrat dalam otot selama melakukan latihan. Air kelapa berpotensi sebagai minuman olahraga karena memiliki derajat keasaman yang rendah, gula seimbang, kandungan mineral, dan bersifat isotonis. Penelitian ini bertujuan mengetahui efek konsumsi air kelapa terhadap ketahanan dan kebugaran berolahraga diukur dari jarak tempuh dan VO2max  selama latihan lari. Penelitian dilakukan di Lapangan FPOK UPI Bandung periode Juli 2015–Februari 2016. Bahan penelitian yang digunakan adalah air kelapa dalam kemasan. Air mineral, air gula 5%, dan minuman olahraga isotonik yang digunakan sebagai pembanding. Subjek penelitian adalah 120 orang laki-laki, berusia 18–23 tahun yang dibagi menjadi 4 kelompok untuk tiap-tiap bahan uji. Setelah pemanasan, subjek berlari secepatnya selama 30 menit. Bahan uji diberikan sebelum dan setiap 10 menit selama lari. Jarak yang ditempuh dicatat dalam satuan meter. Analisis dengan one-way ANOVA yang dilanjutkan dengan uji least significant difference (LSD) dengan α<0,05. Jarak tempuh terpanjang rata-rata dan VO2max tertinggi didapatkan pada kelompok perlakuan air kelapa, diikuti kelompok air gula 5%, minuman olahraga isotonik, dan air mineral (p<0,01). Simpulan, konsumsi air kelapa sebelum dan selama latihan olahraga lari dapat meningkatkan ketahanan olahraga pada laki-laki dewasa bukan atlet.THE EFFECTS OF COCONUT WATER (COCOS NUCIFERA) CONSUMPTION TOWARDS ENDURANCE DURING RUNNING EXERCISE ON NON-ATHLETE ADULT MALEThe endurance in exercising supports optimal physical training to improve physical health and fitness. Two major factors in decreasing sport endurance are dehydration and loss of carbohydrates in muscle during exercise. Coconut water is a potential sports drink because it has low acidity, sugars, minerals content and is isotonic. This research aims to know the effects of coconut water consumption towards endurance and fitness measured from VO2max and mileage during running exercise. The study was conducted in FPOK UPI Bandung during July 2015 to February 2016. Research material used was coconut water, mineral water, 5% sugar water, and isotonic sports drink. The subjects were 120 men, aged 18–23 years old, divided into 4 groups for each of the test material. After warming up, the subjects ran quickly for 30 minutes. Test materials were given before and every 10 minutes during the run. Distance traveled was recorded in units of meters. Data was analyzed using one-way ANOVA test followed by the least significant difference (LSD) test with α<0.05. The longest distance and highest VO2max were obtained by the group treated with coconut water, followed by 5% sugar water, isotonic sports drinks, and mineral waters (p<0.01). In conclusion, coconut water consumption before and during exercise can improve sports endurance on non-athlete adult male.
Efek Konsumsi Suplemen Kalsium dan Magnesium terhadap Dismenore Primer dan Sindrom Premenstruasi pada Perempuan Usia 19–23 Tahun Fen Tih Fen Tih; Cherry Azaria; Julia Windi Gunadi; Rizna Tyrani Rumanti; Alfred Tri Susanto; Alissa Amelia Santoso; Firsty Tasya Evitasari
Global Medical & Health Communication (GMHC) Vol 5, No 3 (2017)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (164.515 KB) | DOI: 10.29313/gmhc.v5i3.2161

Abstract

Dismenore merupakan gangguan menstruasi dengan prevalensi terbesar diikuti gejala sindrom premenstruasi yang mencakup gejala fisik dan psikologis. Asupan mikronutrien kalsium dan magnesium dapat membantu mengatasi keluhan ini. Penelitian ini dilakukan untuk mengetahui pengaruh konsumsi suplemen kalsium dan magnesium terhadap dismenore dan gejala sindrom premenstrual pada perempuan berusia 19–23 tahun. Penelitian ini merupakan eksperimental kuasi dengan rancangan pretes dan postes. Penelitian dilakukan di Universitas Kristen Maranatha Bandung pada bulan Juli–Desember 2016. Subjek penelitian adalah 60 orang perempuan berusia 19–23 tahun, dibagi menjadi dua kelompok secara acak untuk pemberian bahan uji kalsium (1.000 mg/hari) atau magnesium (250 mg/hari) yang diberikan mulai hari kedua menstruasi sampai siklus menstruasi yang berikutnya. Kadar kalsium atau magnesium serum diukur dengan metode spektrofotometri. Dismenore diukur dengan skala nyeri visual analog scale (VAS), sedangkan skor sindrom premenstrual diukur dengan shortened premenstrual assessment form sebelum dan sesudah pemberian bahan uji. Konsumsi kalsium menurunkan skor skala VAS rata-rata pada dismenore dari 6,97 menjadi 3,80 (p=0,000) dan skor total gejala sindrom premenstrual rata-rata dari 15,07 menjadi 10,80 (p=0,000). Konsumsi magnesium mengurangi skor skala VAS rata-rata pada dismenore dari 7 menjadi 4 (p=0,000) dan skor total gejala sindrom premenstrual rata-rata dari 12,27 menjadi 9,87 (p=0,001). Simpulan penelitian ini adalah konsumsi suplemen kalsium atau magnesium mengurangi keluhan dismenore dan gejala sindrom premenstrual pada perempuan usia 19–23 tahun.EFFECT OF CALCIUM AND MAGNESIUM SUPPLEMENTS ON PRIMARY DYSMENORRHEA AND PREMENSTRUAL SYNDROME IN 19–23 YEARS OLD WOMENDysmenorrhea is a menstrual disorder with the greatest prevalence followed by premenstrual syndrome that includes physical and psychological symptoms. Micronutrients intake of calcium and magnesium can help overcome these complaints. This research was conducted to find out the effect of calcium and magnesium supplements consumption on dysmenorrhea and premenstrual syndrome symptoms in 19–23 years old women. This was quasi experimental research with pre- and post-test design. The research was conducted in Maranatha Christian University Bandung from July to December 2016. The subjects of research were 60 women aged 19–23 years old, divided into two groups randomly. One group given calcium (1,000 mg/day) or magnesium (250 mg/day), which was given at the second day of menstruation until the next menstrual cycle. Serum levels of calcium or magnesium were measured with spectrophotometry method. Dysmenorrhea was measured with visual analog scale (VAS), whereas score of premenstrual syndrome was measured with shortened premenstrual assessment form, before and after treatment. The consumption of calcium lowers the VAS score average on dysmenorrhea from 6.97 to 3.80 (p=0.000) and the mean score of premenstrual syndrome from 15.07 to 10.80 (p=0.000). Consumption of magnesium reduces the VAS score average on dysmenorrhea from 7 to 4 (p=0.000) and the mean score of premenstrual syndrome from 12.27 to 9.87 (p=0.001). In conclusion, consumption of calcium or magnesium supplements reduce dysmenorrhea and premenstrual syndrome in women aged 19–23 years old.
Hubungan Antara Ipk Sarjana Kedokteran Dan Program Profesi Dokter Dengan Nilai CBT Uji Kompetensi Program Profesi Dokter Mahasiswa Fakultas Kedokteran Universitas Kristen Maranatha Tih, Fen; Waty, Wenny; Valerie, Rachel; Sanjaya, Ardo; Gunadi, Julia Windi
Jurnal Medika Malahayati Vol 9, No 1 (2025): Volume 9 Nomor 1
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jmm.v9i1.18157

Abstract

Tahapan untuk menjadi dokter perlu melewati tahap sarjana kedokteran lalu program profesi dokter dan diakhiri dengan ujian UKMPPD sebelum akhirnya disumpah dokter. Pada kenyataannya terdapat banyak mahasiswa fakultas kedokteran yang tidak lulus UKMPPD sementara berdasarkan IPK pada tahap sarjana kedokteran dan program profesi dokter dinyatakan lulus. Tujuan penelitian ini adalah mengetahui ada tidaknya korelasi antara IPK sarjana kedokteran dan program profesi dengan nilai CBT UKMPPD. Data diambil pada 2022 di Fakultas Kedokteran Universitas Kristen Maranatha. Penelitian ini melibatkan 1.183 mahasiswa Fakultas Kedokteran Universitas Kristen Maranatha yang mengikuti UKMPPD pada tahun 2016 sampai tahun 2022. Pengolahan data sekunder dilakukan dengan metode analisis bivariat dan multivariat. IPK sarjana kedokteran dan IPK program profesi dokter memiliki korelasi signifikan dengan nilai CBT UKMPPD. Pada tahap Pendidikan profesi seharusnya dalam hal praktik tetap melakukan tindakan sesuai dengan teori yang ada agar sesuai dan relevan dengan pembelajaran teori pada tahap akademik dan CBT UKMPPD.
Comparison of Global Rating Assessment Between Examiners and Simulated Patients on Communication Skills with OSCE Scores: Perbandingan Penilaian Global Rating Antara Penguji dan Pasien Simulasi Pada Keterampilan Komunikasi Dengan Nilai OSCE Waty, Wenny; Hutagalung, Albert Rodney; Tih, Fen; Sanjaya, Ardo; Gunadi, Julia Windi
Jurnal Ilmiah Kesehatan Vol 17 No 1 (2025): Jurnal Ilmiah Kesehatan
Publisher : Universitas Mohammad Husni Thamrin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37012/jik.v17i1.2303

Abstract

Introduction: In the field of medical education, the evaluation process of communication and clinical skills training is known as Objective Structured Clinical Examination (OSCE). OSCE can be assessed using the global rating method, which is a method of subjective evaluation by examiners and standardized patients of student performance. Objective: The study aims to examine the relationship between the subjectivity of examiners and standardized patients in OSCE scores using the global rating method. Methods: The study involved 985 students from the Faculty of Medicine at Maranatha Christian University who participated in the Local OSCE from December 2021 until January 2022. Secondary data were analyzed using logistic regression in SPSS software and presented in tables and multivariate analysis. Results: The global rating assessment by examiners showed a significant relationship with OSCE scores (p<0.001), while the global rating assessment by standardized patients did not show a significant relationship with OSCE scores (p>0.05). This indicates that the evaluation by examiners has a greater influence on OSCE results compared to the assessment by standardized patients. Recommendations: More comprehensive training is needed for standardized patients in conducting assessments using the global rating method to minimize bias. Furthermore, future research is recommended to explore other factors that may influence OSCE assessments to improve the validity and reliability of the evaluation.
Co-Authors Adi K Suprapto, Adi K Albertus Gani Haryono Alfonsa Angwarmase, Alfonsa Alfred Tri Susanto Alissa Amelia Santoso Ardo Sanjaya Cherry Azaria Eliza Nurazizah, Eliza Endang Evacuasiany Ezra Artur Stefano Simanjuntak, Ezra Artur Stefano Firsty Tasya Evitasari Gunadi, Julia Windi Harijadi Pramono Hutagalung, Albert Rodney Indah Kusumawardani, Indah Julia Windi Gunadi MEILINAH HIDAYAT Oliver Rachman Rizamena, Melya Ikbar Rizna Tyrani Rumanti Stella Tinia Hasianna Tresnawati Tresnawati Valerie, Rachel Waty, Wenny Winny Suwindere Yundari, Yundari