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All Journal MANAJEMEN HUTAN TROPIKA Journal of Tropical Forest Management Indonesian Journal of Forestry Research Jurnal Penelitian Hutan dan Konservasi Alam Jurnal Penelitian Hutan Tanaman Journal of Mathematical and Fundamental Sciences Jurnal Wasian BERITA BIOLOGI Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Biologi Tropis Indonesian Journal of Electrical Engineering and Computer Science Jurnal Risalah Kebijakan Pertanian dan Lingkungan Jurnal Ekonomi Jurnal Wasian Jurnal Sylva Lestari Policy Brief Pertanian, Kelautan, dan Biosains Tropika Indonesian Journal of Forestry Research Jurnal Wasian
Tatang Tiryana
Department Of Forest Management, Faculty Of Forestry, Bogor Agricultural University, Academic Ring Road, Campus IPB Dramaga, PO Box 168, Bogor, Indonesia 16680
Agriculture, Biological Sciences & Forestry Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Environmental Science Immunology & microbiology Materials Science & Nanotechnology Mathematics Physics Social Sciences Other

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Journal : BERITA BIOLOGI

 1 
POTENSI MINYAK ATSIRI DAUN ANDALIMAN (Zanthoxylum acanthopodium) SEBAGAI ANTIVIRUS CORONA BERDASARKAN PENAMBATAN MOLEKUL Endang Kintamani; Irmanida Batubara; Cecep Kusmana; Tatang Tiryana; Edi Mirmanto; Fikry Awaludin
BERITA BIOLOGI Vol 21, No 2 (2022): Berita Biologi
Publisher : Research Center for Biology-Indonesian Institute of Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14203/beritabiologi.v21i2.4350

Abstract

Andaliman (Zanthoxylum acanthopodium) plant, a unique spice in the Batak tribe limited only to the fruit. The leaves available most of the time and consisting of essential oils, there are no research has been conducted on molecular docking to determine the potential of the drug. The Covid-19 pandemic is still ongoing, so information as Corona antivirus is needed. This study aims to find the differences of chemical components from Andaliman leaves essential oil, classify the varieties, and get potential components as Corona antivirals based on molecular docking. The Andaliman leaves were collected from North Tapanuli District, than isolated using water distillation and Gas chromatography-mass spectrometry (GC-MS). Data analysis using Principal Component Analysis (PCA) with the XL stat 2020. The results showed that three varieties of Andaliman, Siholpu, Siganjangpat, and Variety three are not grouped in one quadrant. There are 53 compounds were detected. The dominant chemical compounds in all varieties are D-Limonene (Siganjangpat: 87.7%, Siholpu: 50.4%, and Variety three: 42.6%). Each variety is characterized by specific compounds, Siholpu by caryophyllene and sabinene; Singanjangpat by D-Limonene; Variety three by neryl acetate and 1,8-cinneol. The chemical component in Andaliman leaves that most potent as Corona antiviral is beta-caryophyllene in the Siholpu variety.  
Co-Authors Adi Kunarso Agus Sumadi Angga Nalindo Utama Ani Suryani Ari Ardelina Berthold Haasler Bramasto Nugroho Budi Kuncahyo Cecep Kusmana Destyana, Muhammad Resta Dodik Ridho Nurrochmat Dudung Darusman Edi Mirmanto Endang Kintamani Erwin Kusumah Nanjaya Fairus Mulia Faridh Almuhayat Uhib Hamdani Fikry Awaludin Hardjanto Hendy Sumantri Hengki Siahaan I Nengah Surati Jaya Ichsan Suwandhi Irmanida Batubara Lailatul Khasanah Lailatul Khasanah LILIK BUDIPRASETYO Meti Ekayani Muhammad Buce Saleh Muhdin Muhdin Muhdin Muhdin Muhdin Muhdin Muhdin Muhdin Muhdin, Muhdin Mujahidah Sylviari Zaenal Mujahidah Sylviari Zaenal Mujahidah Nining Puspaningsih Nurdin Sulistiyono Priyanto Purwanto Purwanto Putu Ananta Wijaya Rahaju, Sri Robert Parulian Silalahi Syamsu Rijal Teddy Rusolono Tikaputra, Firman Zulkarnain