Wisnu Prabowo
Department Of Obstetrics And Gynaecology, Faculty Of Medicine, Universitas Sebelas Maret/Dr. Moewardi General Hospital, Surakarta

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THE EFFECT OF ABO BLOOD GROUP ON COVID-19 IN PREGNANCY Sri Sulistyowati; Nutria Widya Purna Anggraini; Soetrisno Soetrisno; Eric Edwin Yuliantara; Supriyadi Hari Respati; Muhammad Adrianes Bachnas; Wisnu Prabowo; Hafi Nurinasari; Dympna Pramelita; Dewi Setiyawati; Metharisa Sujana; Aldi Firmansyah
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 3, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss3.art6

Abstract

Background: The COVID-19 virus has spread throughout the world and has been declared as a global pandemic by WHO. Some population groups are more susceptible to COVID-19, and one of them is pregnant women. Pregnancy increases risks of the COVID-19, especially thrombotic complications. The SARS-CoV-2 infection may vary widely from asymptomatic to severe infection. Some studies have shown that ABO blood group can be a marker of susceptibility to some disease progression. Objective:This study aims to investigate relationships between the ABO blood group, the COVID-19 infection and its complications in pregnant women at Dr. Moewardi Hospital, Surakarta.Methods: This study was an observational analytic study with a cross-sectional study design involving 40 pregnant women infected with COVID-19 at Dr. Moewardi Hospital, Surakarta. COVID-19 PCR swabs on the women were administered on their oropharynx and nasopharynx, and laboratory examination of the ABO blood group in all samples was performed. Comparative data distribution of blood groups in the population and the global population distribution were calculated by Chi Square Goodness of Fit. Comparative data between ABO blood group distributions, blood parameters and complications (respiratory, thrombotic, other infections, and death) were calculated by Chi square test and then by One-Way ANOVA. Next, correlation tests for the complications of the blood group and the ages applied a multinomial regression.Results: There were significant differences of thrombotic complications on the blood group of pregnant women infected with COVID-19 (p=0.027). Blood type B significantly tended to experience thrombotic complications when compared to other blood groups (p=0.022).Conclusion: The ABO blood group could affect the complication levels in the pregnant women infected with the COVID 19.
Rontgen Toraks, Nilai Cycle Threshold dan Hubungannya dengan Tingkat Keparahan Klinis pada Ibu Hamil dengan COVID-19 di RSUD Dr. Moewardi Immanuela Maria Regita; Eriana Melinawati; Wisnu Prabowo; Uki Retno Budihastuti
Plexus Medical Journal Vol. 2 No. 6 (2023): Desember
Publisher : Fakultas Kedokteran, Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/plexus.v2i6.634

Abstract

Pendahuluan: Penggunaan pemeriksaan penunjang dalam mendiagnosis COVID-19 pada ibu hamil merupakan sebuah tantangan karena perubahan fisiologis yang unik pada ibu hamil menyebabkan variasi hasil. Kerentanan ibu terhadap patogen mungkin dapat berisiko menjadi perkembangan ke arah penyakit yang lebih parah. Namun terdapat kesimpangsiuran data pada hubungan pemeriksaan laboratorium seperti radiologi dan RT-PCR terhadap keparahan klinis ibu hamil. Oleh karena itu, penelitian ini bertujuan untuk mempelajari nilai CT, gambaran rontgen toraks dan hubungannya dengan tingkat keparahan klinis pasien ibu hamil dengan COVID-19. Metode: Data diperoleh dari rekam medis di rumah sakit tingkat tersier di Surakarta, Indonesia. Ibu hamil yang menjalani tes RT-PCR dan foto rontgen dada selama rawat inap pada periode Januari sampai Desember 2021 diperiksa. Nilai CT dari hasil RT-PCR positif dimasukkan dalam data penelitian. Keparahan ibu hamil berdasarkan presentasi klinis dibagi menjadi tiga kelompok: ringan, sedang dan berat. Data yang diperoleh kemudian dianalisis. Hasil: Terdapat enam puluh tujuh data ibu hamil pada penelitian ini. Rerata usia kehamilan saat admisi adalah 38 minggu. Karakteristik seperti usia, usia kehamilan, komorbid tidak mempengaruhi keparahan klinis. Nilai CT gen ORF1ab dan gen E tidak berhubungan dengan tingkat keparahan klinis. Namun korelasi signifikan ditemukan antara gambaran rontgen dada dan keparahan klinis penyakit (p=0.000, r=0.486). Kesimpulan: Tidak ada hubungan yang signifikan secara statistik antara nilai CT dan tingkat keparahan klinis ibu hamil. Namun, terdapat hubungan signifikan secara statistik antara rontgen toraks dan tingkat keparahan klinis ibu hamil.