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All Journal KOVALEN: Jurnal Riset Kimia Jurnal FARMAKU (Farmasi Muhammadiyah Kuningan) ad-Dawaa : Journal of Pharmaceutical Sciences Mattawang: Jurnal Pengabdian Masyarakat JIFI (Jurnal Ilmiah Farmasi Imelda) Jurnal Pengabdian Kefarmasian Duta Abdimas: Jurnal Pengabdian Masyarakat Gema Kesehatan Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat Medical Sains : Jurnal Ilmiah Kefarmasian
Ayu Wulandari
STIFA Pelita Mas Palu
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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GAMBARAN PENGGUNAAN OBAT DIARE DI PUSKESMAS GIMPU KECAMATAN KULAWI SELATAN Ayu Wulandari
Jurnal Farmaku (Farmasi Muhammadiyah Kuningan) Vol 5 No 1 (2020): Volume 5 Nomor 1 Maret 2020
Publisher : STIKes Muhammadiyah Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (517.667 KB) | DOI: 10.55093/jurnalfarmaku.v5i1.84

Abstract

Diare adalah suatu penyakit yang ditandai dengan meningkatnya frekuensi buang air besar lebih dari tiga kali sehari disertai dengan adanya perubahan bentuk dan konsistensi tinja penderita. Tujuan penelitian ini adalah untuk mengetahui seberapa besar gambaran pola penggunaan obat pada pasien Diare yang diberikan kepada pasien di Puskesmas Kulawi. Penelitian ini menggunakan desain penelitian deskriptif yaitu penelitian yang dimaksudkan untuk mengangkat fakta, keadaan dan variable yang terjadi selama penelitian berlangsung dan menyajikan apa adanya. Hasil penelitian ini menunjukan bahwa penderita penyakit diare berdasarkan jenis kelamin denganjumlah persentase laki-laki sebnayak 46% dan perempuan sebanyak 54%. Berdasarkan usia 0-4 Tahun 28%, 5-14 tahun 32%, 15-24 tahun 4%, 25-44 tahun 12%, 45-64 16% dan ≥ 65 tahun 8%. Berdasarkan penggunaan obat oralit 73,13%, cotrimoxazole 23,89%, metronidazole 2,98%. Pada terapi penunjang paracetamol 29,93%, neo diastop 19,70%, zinc 18,25%, CTM 2,92%, extrak belladonna 11,68%, BComp 1,46%, domperidone 5,11%,antasida 8,03%. Dari hasil ketepatan dan ketidaktepatan penggunaan obat diperoleh 100% tepat berdasarkan Pedoman Pengobatan Dasar di Puskesmas.
Education on Handling Hypertension and Blood Pressure Checks at Petobo Huntara Central sulawesi: Edukasi Penanganan Penyakit Hipertensi dan Pemeriksaan Tekanan darah Di Huntara Petobo Sulawesi Tengah Syafika Alaydrus; Niluh Puspita Dewi; Wayan Wirawan; Ayu Wulandari
Mattawang: Jurnal Pengabdian Masyarakat Vol. 3 No. 1 (2022)
Publisher : Yayasan Ahmar Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (731.564 KB) | DOI: 10.35877/454RI.mattawang823

Abstract

Hypertension is another name for high blood pressure. Blood pressure itself is the force of blood flow from the heart that pushes against the walls of blood vessels (arteries). Hypertension is a condition in which blood pressure is higher than 140/90 mmHG. This counseling was carried out by a team of Stifa Pelita Mas Palu lecturers totaling 4 people assisted by several students and carried out at Banua Huntara Petobo, with a total of 108 participants. Educational results based on discussions show that there are differences in knowledge about hypertension before and after being given education. Abstrak Hipertensi adalah nama lain dari tekanan darah tinggi. Tekanan darah itu sendiri adalah kekuatan aliran darah dari jantung yang mendorong dinding pembuluh darah (arteri). Hipertensi adalah kondisi di mana tekanan darah lebih tinggi dari 140/90 mmHG. Penyuluhan ini dilakukan oleh tim dosen Stifa Pelita Mas Palu yang berjumlah 4 orang di bantu beberapa mahasiswa dan dilakukan di Banua Huntara Petobo, dengan jumlah peserta sebanyak 108 orang. Hasil Edukasi berdasarkan diskusi menunjukkan bahwa ada perbedaan pengetahuan tentang hipertensi sebelum dan sesudah diberikan edukasi.
Aktivitas Afrodisiak Ekstrak Etanol Daun Tumbuhan Bungkus (Smilax rotundifolia L.) terhadap Fertilitas Tikus Putih Jantan (Rattus norvegicus): The Aphrodisiac Activity of Ethanol Extract of Bungkus Leaf (Smilax rotundifolia L.) on The Fertility of White Male Rats (Rattus norvegicus) Ayu Wulandari; Recky Patala; Kiki Rizki Handayani; Monica Sandra Makatang
KOVALEN: Jurnal Riset Kimia Vol. 8 No. 3 (2022): December Edition
Publisher : Chemistry Department, Mathematics and Natural Science Faculty, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/kovalen.2022.v8.i3.15825

Abstract

Aphrodisiac is a substance that can increase stamina, libido (sexual desire), and male fertility. This study aims to determine the secondary metabolites contained in the leaves of the Bungkus plant (Smilax rotundifolia L.), to determine the aphrodisiac activity of the leaf extract of the Bungkus plant on the fertility parameters of male white rats (Rattus norvegicus). This study used an experimental method with a modified post-test randomized controlled group design using 15 male white rats and 30 female white rats which were divided into 3 treatment groups, namely pairing each male rat with 2 female white rats (1 : 2). Each group consisted of 5 male rats and 10 female rats, namely the normal control group (NaCMC 0.5%), the positive control group (X-Gra 51.37 mg/kgBW), the control group the leaf extract test sample of the Bungkus plant (S. rotundifolia L.) with a dose of 200 mg/kgBW. The research data were analyzed using the SPSS 25 statistical test. The results of this study indicate that the leaf extract of the Bungkus plant contains secondary metabolites flavonoids, saponins, alkaloids and tannins. The administration of Bungkus leaf extract at a dose of 200 mg/kgBW showed a difference in the percentage value of the pregnancy index and a significant effect on the fertility index value.
Pembuatan Obat Nyamuk Herbal Sebagai Alternatif Pembasmi Nyamuk Di Desa Sopu Kabupaten Sigi Ayu Wulandari; Monica Sandra; Suci Rahmayanti
Duta Abdimas Vol. 1 No. 1 (2022): Duta Abdimas: Jurnal Pengabdian Masyarakat
Publisher : LPPM Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1237.737 KB) | DOI: 10.47701/abdimas.v1i1.1585

Abstract

Aedes is a genus of mosquitoes that often cause health problems. The genus Aedes is a biological vector of DHF (Dengue Hemorrhagic Fever). Concern over the current outbreak of DHF (Dengue Hemorrhagic Fever) has resulted in the use of many chemical-based insect repellents such as insecticides to eradicate mosquitoes. However, these things can cause toxic residues that are harmful to human and livestock health, environmental pollution and can cause unwanted effects such as natural enemies if used continuously and for a long time. Currently, electric mosquito repellent is one of the people's choices. Therefore, to make people aware of the importance of high selectivity in using mosquito repellent that is safe for health and the environment, it is necessary to have community service regarding and training regarding the use and manufacture of herbal mosquito repellent. Hernal mosquito repellent is made from a mixture of natural ingredients that contain nicotinic substances that can protect us from mosquitoes. The materials used for the manufacture of mosquito repellent are very easy to find or easy to obtain. Because it only uses orange peel and garlic as the basic ingredients. The method of manufacture is also very easy so that it is also easy to apply among housewives. The manufacture of herbal mosquito repellent made from garlic and orange peel is an alternative as an insect repellent that is safe for health in terms of the ingredients
Penyuluhan Pemanfaatan Obat Tradisional Berbasis Kearifan Lokal Untuk Penyakit Diabetes Melitus Ayu Wulandari; Ernawati Ernawati
Jurnal Pengabdian Kefarmasian Vol 4, No 1 (2023): JURNAL PENGABDIAN KEFARMASIAN
Publisher : Jurusan Farmasi Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/jpk.v4i1.3361

Abstract

Diabetes mellitus, also known by the public as diabetes, is a chronic metabolic disorder characterized by an increase in the concentration of glucose in the blood (hyperglycemia). The use of plants as medicine is no stranger to Indonesian people wherever they are. The use of medicinal plants has been carried out for a long time by the ancestors which then developed and produced a local wisdom. Local wisdom is a community life behavior in interacting with an environment in a place or area. This local wisdom can be internalized, practiced, taught, and passed down from generation to generation. Based on information collected from the survey team, the people of Maku village have used many plants which are known to have benefits as an alternative to synthetic drugs, especially for Diabetes Mellitus. Information about the types of traditional medicines, terms, and conditions for traditional medicines that are not evenly distributed can lead to errors in use. Knowledge of traditional medicine is widely owned by the community, but there are some people who do not understand the types of plants that are useful in traditional medicine and how to use them. The purpose of this community service activity is to provide socialization to the Maku village community about the use of plants as traditional medicines based on local wisdom for diabetes mellitus. This Community Service activity is carried out in the form of outreach and education using lecture and discussion methods. Based on the score of the results of community satisfaction with extension activities, namely 89.17% (very good). These results indicate that the participants' knowledge increased after being given counseling.Keywords: Diabetes Mellitus, Maku Village, Sigi, Traditional Medicine, local wisdomDiabetes melitus yakni penyakit metabolik menahun yang dilihat dari meningkatnya konsentrasi glukosa darah (hiperglikemia). Masyarakat Indonesia sudah tidak asing lagi menggunakan tumbuhan sebagai obat ke mana pun mereka pergi. Pemanfaatan tumbuhan obat telah lama dipraktikkan oleh nenek moyang lalu berkembang serta menghasilkan kearifan lokal. Kearifan lokal yakni gaya hidup bersama yang berinteraksi dengan lingkungan yang berlaku di suatu tempat ataupun daerah. Kearifan lokal ini bisa dihayati, dipraktikkan, diajarkan serta diwariskan dari generasi ke generasi. Berdasarkan informasi yang dihimpun tim peneliti, masyarakat Desa Maku banyak memanfaatkan tumbuhan yang dikenal khasiatnya sebagai alternatif obat sintetik, terutama untuk penyakit diabetes melitus. Informasi terkait jenis obat tradisional serta kondisi obat tradisional yang tidak merata bisa memicu kesalahan penerapan. Pengetahuan pengobatan tradisional umumnya sudah diketahui masyarakat, namun sebagian masyarakat belum memahami jenis tumbuhan apa saja yang bermanfaat untuk pengobatan tradisional dan cara pemanfaatannya. Tujuan dari kegiatan bakti sosial ini yakni untuk mengedukasi masyarakat desa Maku terkait pemanfaatan tumbuhan sebagai obat tradisional berbasis kearifan lokal pada penyakit diabetes melitus. Kegiatan ini dilaksanakan di dalam bentuk sosialisasi serta pelatihan dengan metode ceramah serta diskusi. Berdasarkan skor kepuasan masyarakat terhadap kegiatan penyuluhan yaitu H. 89,17% (sangat baik). Temuan ini menunjukkan bahwa pengetahuan peserta meningkat sesudah penyuluhan.Kata kunci : Diabetes Melitus, Obat Tradisional, Kearifan Lokal, sigi
TOTAL FLAVONOID AND ANTIOXIDANT ACTIVITY OF ETHANOL EXTRACT FROM JAVA PLUM (Syzygium cumini L.) LEAF Muthmainah Tuldjanah; Ayu Wulandari
GEMA KESEHATAN Vol. 14 No. 2 (2022): Desember 2022
Publisher : POLTEKKES KEMENKES JAYAPURA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Juwet leaf is a plant with antioxidant properties that protect against free radicals. The simplicia ethanol extract of juwet leaves used came from the city of Palu, Central Sulawesi. Extraction of chemical content from juwet leaves (Syzygium cumini L.) was carried out by maceration method. In this study, to determine the levels of flavonoid compounds and antioxidant power in the sample extract, a compound analysis was carried out using a UV_Vis spectrophotometer. Total flavonoid content was determined from the absorbance value obtained from a wavelength of 510 nm by using Visible spectrophotometry. Antioxidant activity was obtained by measuring the reducing activity of the ethanol extract of juwet leaves on the free radical DPPH (1,1-Diphenyl-1-picrylhydrazil) by Visible spectrophotometry with a wavelength of 517 nm. An antioxidant activity test was carried out using quercetin as a comparison. The results showed that the ethanol extract of juwet leaves had low total flavonoid content with weak antioxidant activity compared to quercetin. Keywords: Antioxidants, Flavonoids, Juwet leaves
Effectiveness Of Cassia alata L Leaf Extract Decrease Blood Glucose Level On Streptozotocin-Induced Male White Rats Niluh Puspita Dewi; Febry Grasela Aula; Indah Kurnia Utami; Ayu Wulandari; Rezky Yanuarty; Wayan Wirawan
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol. 6 No. 1 (2023)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v6i1.38400

Abstract

Introduction: Diabetes mellitus (DM) is a condition in which the body either fails to produce enough insulin at the right time or fails to use it properly. Aims: The goal of this study is to show how Cassia alata L. leaf extract affects blood glucose levels in streptozotocin-induced diabetic rats. Methods: Cassia alata L. leaves therapy is an alternative treatment for DM. In this investigation, laboratory techniques were employed. Streptozotocin was administered intraperitoneally to mice at a dose of 40 mg/kg body weight initially. Except that they produce normal controls. Six groups of 30 rats each received treatment with Cassia alata L. leaf extract at doses of 500 mg/kg body weight, 600 mg/kg body weight, and 700 mg/kg body weight in addition to the usual control group. Trial outcome data were first examined using one-way ANOVA to confirm differences between treatments and then put through the DUNCAN trial. Result: As a result, it was discovered that secondary metabolites of alkaloids, flavonoids, saponins, and tannins were present in the ethanol extract of Cassia alata L. leaves. A dose of 700 mg/kg body weight is an effective blood sugar-lowering dose, with an average reduction of 121 mg/dl. Conclusion: Ethanol extract from Cassia alata L. leaves has this effect.
PROFIL PENGGUNAAN OBAT PASIEN JANTUNG KORONER DI RAWAT INAP RUMAH SAKIT UMUM WIRABUANA PALU Ayu Wulandari
Jurnal Farmasindo Vol 5 No 1 (2021): Juni
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Penyakit Jantung Koroner merupakan salah satu bentuk penyakit kardiovaskuler yang menjadi penyebab kematian nomor satu di dunia dan suatu penyakit degeneratif yang berkaitan dengan gaya hidup juga social ekonomi masyarakat. Penyakit ini terjadi karena adanya penyempitan arterikoroner yang biasa disebut arteriosclerosis. Tujuan penelitian ini adalah untuk mengetahui profil penggunaan obat dan kerasionalan penggunaan obat jantung koroner pada pasien jantung koroner dibagian rawat jalan di Rumah Sakit Wirabuana Palu. Dalam penelitian ini kesesuaian terapi dilakukan dengan mengevaluasi kerasionalan terapi yang meliputi tepat obat, tepat indikasi, tepat pasien, tepat dosis dan efek samping. Jenis dan rancangan penelitian ini adalah penelitian observasional, disusun dengan metode deskriptif dan data diperoleh secara cross sectional. Pengambilan sampel dilakukan dengan menggunakan metode total sampling dan sebanyak 42 data diambil sebagai sampel. Berdasarkan hasil penelitian dari analisis rasionalitas terapi penggunaan obat jantung koroner, diperoleh hasil yaitu 100% tepat obat, 100% tepat indikasi, 100% tepat pasien, 100% tepat dosis dan 100% waspada efek samping. Hasil penggunaan obat jantung koroner yang paling banyak digunakan yaitu amlodipin sebesar 25%.
EVALUATION OF APHRODISIAC ACTIVITY OF ETHYL ACETATE FRACTION OF CLOVE LEAVES (Syzygium aromaticum L.) IN MALE WHITE RATS (Rattus norvegicus) Muthmainah Tuldjanah; Rezky Yanuarty; Agung; Ayu Wulandari
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 4 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i4.918

Abstract

Clove leaves contain antioxidant compounds such as saponins, flavonoids, tannins, sterols, and essential oils. Among those chemical constituents, eugenol, eugenol acetate, caryophyllene, and sesquiterpenes were believed to have aphrodisiac activity. This study aims to investigate the potential aphrodisiac effects of the ethyl acetate fraction of clove leaves (Syzygium aromaticum L) administered at a dose of 250 mg/kg BW. The research employed an experimental method with a modified post-test randomized controlled group design and utilized a total of 45 white rats, consisting of 15 males and 30 females, divided into three treatment groups in a 1:2 ratio. Each group consisted of 5 male rats and 10 female rats. The three groups included the healthy control group (Na-CMC 0.5%), the positive control group (treated with X-Gra 52.5 mg/kg body weight) and the treatment group receiving clove leaf extract samples at a dosage of 250 mg/kg BW. The results indicate that the ethyl acetate fraction of clove leaves contains steroids and alkaloids with mount latency (ML), intromission latency (IL) ejaculation latency (EL), mount frequency (MF), intromission frequency (IF) and ejaculation frequency (EF) of 11.40 s, 15.80 s, 6.228 s, 23.60, 14.60, and 1.60 s, respectively. Based on these findings, it can be concluded that it has the potential to be used as an aphrodisiac agent. Keywords: Aphrodisiac, Syzygium Aromaticum L., ethyl acetate fraction, clove leaves, ejaculation frequency
POLA PENGGUNAAN OBAT ANTIDIABETES PADA PASIEN RAWAT INAP RSUD ANUTAPURA PALU Budiawan, Erick; Gloria, Yovanka Lista; Wulandari, Ayu
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 7 No. 1 (2023): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v7i1.1484

Abstract

This study aims to determine the pattern of antidiabetic treatment and the accuracy of the use of antidiabetic drugs based on indications, drugs, patients, and doses of use at Anutapura Hospital Palu. This study is a descriptive research method using a cross-sectional method with retrospective data collection based on medical record data for type 2 Diabetes mellitus patients in 2021. Sampling was carried out using a minimized sampling technique with medical record data of 30 patients based on inclusion criteria. The results of this study are patients with Type 2 Diabetes Mellitus, which are female, as many as 16 patients (54%), in the age range of 48-60 years as many as 14 patients (46%), the most widely used oral antidiabetic drug group is Biguanid group (Metformin) as many as 18 patients (70%), the type of insulin drug that was most widely used was Novorapid as many as 13 patients (61.91%), and adjunctive drugs with the highest use of therapy, namely Amlodipine as many as 14 patients with a percentage (7, 4%). Antidiabetic treatment is based on the right indication (100%), right drug (50%), right patient (93%) and right dose (100%).
Co-Authors Agung Budiawan, Erick Ernawati Ernawati Febry Grasela Aula Gloria, Yovanka Lista Indah Kurnia Utami Kiki Rizki Handayani Monica Sandra Monica Sandra Makatang Muthmainah Tuldjanah Niluh Puspita Dewi Palumpun, Tri Olan Recky Patala Rezky Yanuarty Rezky Yanuarty Sarwadana, I Made Suci Rahmayanti Syafika Alaydrus Wayan Wirawan Wayan Wirawan