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All Journal Disease Prevention and Public Health Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Pharmasipha JPSCR : Journal of Pharmaceutical Science and Clinical Research FITOFARMAKA: Jurnal Ilmiah Farmasi Jurnal Ilmu Kefarmasian Indonesia Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Majalah Farmasetika Journal of Innovation in Community Empowerment (JICE) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Journal of Pharmaceutical (JOP) Kreativasi: Journal of Community Empowerment Jurnal Ekonomi Kesehatan Indonesia
Sugiyono
Program Studi Farmasi, Universitas Jenderal Achmad Yani Yogyakarta, Yogyakarta, Indonesia
Religion Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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The Relationship Between Oral Antidiabetic Treatment And Blood Sugar Level Among Type 2 Diabetes Mellitus Patients in Nur Hidayah Hospital Yogyakarta. Pujilestari, Mardiana; Titami, Arina; Sugiyono, Sugiyono
Disease Prevention and Public Health Journal Vol. 19 No. 1 (2025): Disease Prevention and Public Health Journal
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/dpphj.v19i1.11948

Abstract

Background: Diabetes mellitus is a chronic disease that poses a global health threat, with type 2 diabetes mellitus accounts for 90% of all cases. In Indonesia, diabetes mellitus is among the causes of high mortality due to non-communicable diseases. If not treated properly, type 2 diabetes mellitus can lead to various complications, potentially worsening the patient's condition. To address this, blood glucose levels must be controlled through the use of oral antidiabetic medications, either as monotherapy or in combination therapy. This study aims to the accuracy of oral antidiabetic drugs use and its therapy outcomes (blood sugar levels) in type 2 diabetes mellitus patients at Nur Hidayah Hospital Yogyakarta. Method: This study is an observational study with retrospective data collection, carried out using the purposive sampling method. A total of 75 samples were obtained from 298 populations that met the specified criteria. Univariate data analysis methods are presented in the form of percentages and tables, including analyses of patient characteristics, treatment characteristics, and therapy outcomes. Subsequently, bivariate analysis was conducted using the chi-square test to determine the relationship between the accuracy of oral antidiabetic drugs use and therapy outcomes, specifically blood sugar levels of patients with type 2 diabetes mellitus. Results: The findings of the analysis performed using the chi-square test revealed a correlation between the accuracy of oral antidiabetic medication and blood sugar levels in patients (p-value=0.012). Conclusion: proper use of oral antidiabetics shows that the patient's blood sugar levels are controlled.
Hubungan rasionalitas penggunaan obat antihipertensi dengan luaran klinik di RS PKU Muhammadiyah Gamping Sugiyono, Sugiyono; Putri, Shabela Alifia
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol. 9 No. 1 (2025): Maret
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v9i1.12623

Abstract

Hypertension is an increase in a person's blood pressure above normal, namely systolic and diastolic blood pressure ≥140/90 mmHg. Rational use of medication can describe the health quality of hypertensive patients based on the parameters of the right indication, the right patient, the right drug and the right dose. The study aimed to determine the relationship between the rationality of using antihypertensive drugs and clinical outcomes in hypertensive patients who were hospitalized at PKU Muhammadiyah Gamping Hospital. The research method is non-experimental analytical with retrospective data collection using purposive sampling for data from January 2021-March 2024 with a sample size of 63 patients. The research results showed that the rationality of using antihypertensive drugs was based on an indication accuracy of 100%, patient accuracy of 100%, appropriate medication of 84.13% and dose suitability of 96.83%. Patients who received rational antihypertensive medication were 80.95% (51 patients) and 32 patients (50.79%) showed that blood pressure was achieved. Data analysis in research uses the Chi-Square test. The results of the Chi-square test obtained a p value = 0.096>0.05 so there is no relationship between the rationality of using antihypertensive drugs and clinical outcomes.
Correlation between Personnel Knowledge and Suitability of Intravenous Admixture Preparations at PKU Muhammadiyah Wonosari Hospital Madury, Shalahuddin Al; Wiedyaningsih, Chairun; Sugiyono, Sugiyono; Mutiara, Rina
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 15, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.101813

Abstract

Background: Knowledge and skills related to the preparation and administration of sterile preparations, including the principles of technique aseptic according to procedures, are very important for personnel is compounding intravenous admixture. This knowledge is essential to avoid medication errors and increase patient safety. Improper preparation or administration of intravenous medications can result in patient injury or even death due to medication errors.Objectives: The purpose of this study is to examine the correlation between the appropriateness of antibiotic intravenous admixture preparations and the degree of personal knowledge.Methods: This research was conducted in an observational manner with a cross-sectional design and quantitative analysis. A total of 33 respondents who were in charge of intravenous admixture preparations at PKU Muhammadiyah Wonosari Hospital were measured for their level of knowledge and tested for their relationship with the suitability iv admixture process in the October-November 2022 period and analyzed statistically with the contingency coefficient correlation test.Results: The results of this study showed a p-value of 0.001 indicating a significant correlation between the level of knowledge and suitability for the preparation stage. A p-value of 0.012 indicated a correlation between the level of knowledge and modification of the intravenous injection preparation mixing procedure. Personal profession and training have an effect on the mixing of intravenous injection preparations with a p-value of 0.021; and 0.027.Conclusion: Increased knowledge and continuous training can be implemented to improve the quality of intravenous admixture produced by personnel.
Pemanfaatan Media Sosial Dalam Meningkatkan Pengetahuan dan Kepatuhan Pasien Diabetes Melitus Siwi Padmasari; Sugiyono Sugiyono
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 9, No 2 (2024)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v9i2.74336

Abstract

Teknologi digital menjadi sumber daya penting untuk penyampaian layanan kesehatan. Mobile Health yang efektif digunakan pada pelayanan kesehatan, tetapi belum banyak diteliti adalah edukasi melalui penggunaan media WhatsApp (WA). Penelitian ini bertujuan untuk mengetahui efektivitas edukasi penggunaan obat menggunakan media sosial WA dalam meningkatkan pengetahuan dan kepatuhan pasien Diabetes Melitus Tipe 2. Desain yang digunakan dalam penelitian ini menggunakan desain penelitian quasi experimental, pretest-posttest design with control group dan pengambilan sampel menggunakan cara convenience sampling. Kelompok perlakuan akan mendapatkan edukasi penggunaan obat antidiabetik oleh apoteker melalui pesan teks dan leaflet melalui aplikasi WA setiap minggu selama 1 bulan. Pengukuran tingkat pengetahuan menggunakan kuisioner Diabetes Knowledge Questionnaire-24 (DKQ24) dan pengukuran kepatuhan menggunakan kuisioner Medication Adherence Report Scale-5 (MARS-5). Data karakteristik pasien dianalisis secara deskriptif. Data tingkat pengetahuan dan kepatuhan sebelum dan sesudah intervensi dianalisis dengan menggunakan uji Wilcoxon dan uji Mann-Whitney untuk mengetahui perbedaan antara kedua kelompok. Karakteristik pasien DM tipe 2 di Puskesmas Mlati II mayoritas berusia >45 tahun, jenis kelamin perempuan, memiliki tingkat pendidikan SMA, dan memiliki penyakit penyerta hipertensi. Pemberian edukasi pesan teks dan leaflet melalui WA dapat meningkatkan pengetahuan responden pada kelompok intervensi secara signifikan dengan nilai ∆4,71 (p=0,000) dibandingkan dengan kelompok kontrol dengan nilai ∆2,59 (p=0,073). Tingkat kepatuhan pada kelompok intervensi mengalami peningkatan secara signifikan dengan nilai ∆7,74 (p=0,000) dibandingkan dengan kelompok kontrol dengan nilai ∆6,65 (p=0,069). Kesimpulan dari penelitian ini adalah terdapat hubungan yang signifikan antara edukasi yang dilakukan oleh apoteker melalui media WA terhadap tingkat pengetahuan dan kepatuhan pada pasien DM tipe 2 (p<0,05).
Gambaran Potensi Interaksi Obat Amlodipin pada Pasien Hipertensi di Instalasi Rawat Jalan Puskesmas Mlati I Sleman Yogyakarta Fatlah Furqon Kholik; Mardiana Puji Lestari; Sugiyono Sugiyono; Lutfi Hidiyaningtyas
JOURNAL OF PHARMACEUTICAL (JOP) Vol. 4 No. 1 (2026): Journal of Pharmaceutical (JOP)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) UNIVERSITAS JENDERAL ACHMAD YANI YOGYAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30989/jop.v4i1.2034

Abstract

Background: Hypertension is one of the chronic diseases with high prevalence which is the main cause of death. One of the first lines of hypertension treatment is amlodipine. Amlodipine can be given as monotherapy, but if it is not effective in lowering blood pressure, then combination antihypertensive therapy can be given. The use of amlodipine together with various other drugs in hypertensive patients increases the risk of drug interactions that can affect the effectiveness of treatment. Research Objective: To determine the potential for drug interactions between amlodipine and other drugs in outpatients with hypertension at the Mlati I Sleman Health Center, Yogyakarta, January–December 2024. Research Methods: This study design was descriptive observational with a retrospective approach. A sample of 96 patients who met the inclusion criteria were taken using a purposive sampling technique. Data were collected from medical records and drug interactions were analyzed using Drugs.com. Data were analyzed univariately including patient characteristics, drug characteristics, and potential drug interactions. Research Results: The majority of patients were aged 56–65 years (29.17%), female (64.58%), and had comorbidities (83.33%). Amlodipine was mostly used in hypertensive patients alone (92.71%). The number of drugs used in this study was mostly <5 drugs (93.75%). From the evaluation results, 40 patients (41.67%) experienced potential drug interactions. Of the 47 drug interactions, the majority were moderate in severity (55.32%) with a pharmacodynamic drug interaction mechanism of 68%. Conclusion: There is a potential for amlodipine drug interactions in outpatient hypertensive patients, most of which are moderate with a pharmacodynamic mechanism.
Co-Authors Anggeraini , Via Gusti Chairun Wiedyaningsih Fatlah Furqon Kholik Husna, Nadia Lestari, Mardiana Puji Lutfi Hidiyaningtyas Nadia Husna Niken Larasati Niken Larasati Padmasari Padmasari Padmasari, Siwi Pangestika, Annisa Pujilestari, Mardiana Putri, Shabela Alifia Reza Iqbal Suhada Rina Mutiara, Rina Shalahuddin Al Madury, Shalahuddin Al Sugiyono Sugiyono Titami, Arina Yuni Andriani Yuni Andriani Yunilistianingsih, Yunilistianingsih