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Literature Review: Bahan Alam yang Berpotensi sebagai Antidiabetes: Literature Review: Natural Ingredients that Have Potential as Antidiabetic Novalinda Novalinda; Mukti Priastomo; Laode Rijai
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 14 (2021): Proceeding of Mulawarman Pharmaceuticals Conferences
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (280.194 KB) | DOI: 10.25026/mpc.v14i1.595

Abstract

Antidiabetes is a treatment that is currently much needed for diabetics, because the cost of treatment is getting higher, so it is recommended to use herbs as an alternative treatment. This study aims to determine natural ingredients that have the potential as antidiabetic. The method used is a systematic review by collecting, analyzing and summarizing 25 journals with the publication year 2016-2021 with keywords namely Antidiabetes, Natural Ingredients, and In Vivo. The results of the journal analysis are Beluntas leaves 0.9 mg/20 gBW, Kecombrang leaves 100 mg/kgBW, Keji Beling leaves 300 mg/kgBW, Kembang Bulan leaves 5.14 ml/200gBW, Kenikir leaves 1400 mg/200gBW, Mango leaves 105 mg /kgBW, Pucuk Merah leaves 100 g/kgBW, Rambutan leaves 50 mg/kgBW, Sambiloto leaves 40 mg/kgBW, Breadfruit leaves 600 mg/kgBW, Avocado seeds 150 mg/kgBW, Kebiul seeds 51mg/20gBW, Green Coffee Beans Arabica 400 mg/kgBW, Dates seeds 10 mL/day, Pumpkin seeds 720 mg/kgBW, Okra seeds 5,46 mg/gBW, Areca seeds 750 mg/kgBW, Buni bark 200 mg/kgBW, Faloak bark 150 mg /kgBW, Surian bark 150 mg/kgBW, Bilimbi fruit 750 mg/kgBW, Purple Sweet Potato fruit 150 mg/kgBW, Papaya flower 200 mg/kgBW, Pineapple peel 250 mg/kgBW and Black Garlic tuber 300 mg/kgBW with this optimal dose can reduce blood glucose levels.
Antianemic Activity of Coconut (Cocos nucifera) Haustorium Waste Filtrate in Mice Induced by Sodium Nitrite Adzimahtinur Pradawahyuningtyas; Mukti Priastomo; Laode Rijai
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 3 No 2 (2020)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v3i2.16477

Abstract

This study aims to determine the antianemic activity of coconut haustorium (Cocos nucifera) waste against mice induced by sodium nitrite orally for 43 days. The condition of anemia was determined by calculating the hemoglobin level using the Point of Care Test (POCT) method with the easytouch® GCHb and the resulting Hb level was 7.96 ± 0.05 g/dL. After the anemia condition is achieved, the test treatment is given for 21 days by dividing the mice into four groups, each consisting of three mice. The blank group (I) was administered distilled water, the control group (II) was administered Inbion® supplements at a dose of 0.65 mg/20 g BW, groups III and IV were administered coconut haustorium filtrate at a dose of 5 and 15 g/kg, respectively. Then measured the hemoglobin level and the number of erythrocytes. Based on the results of the study, the average hemoglobin levels of the blank, control, I and II groups were 13,9; 15,4; 16,0; and 16.8 g / dL, respectively. The number of erythrocytes during anemia was 1,750,000 / mm3 and after giving coconut kentos was 8,260,000 / mm3. From this study it can be concluded that the highest anti-anemia activity showed by coconut haustorium waste filtrate at dose 15 g/kgBW and had a significant difference in hemoglobin levels (p <0.05) with the blank group.
The Effect of Papaya (Carica Papaya L.) Leaves on Adolescents with Dysmenorrhea Desy Aulia Rahmah; Mukti Priastomo; Laode Rijai
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 3 No 2 (2020)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v3i2.16478

Abstract

Papaya leaves (Carica papaya L.) contain active compounds of flavonoids and alkaloids which have the function of reducing dysmenorrhea. Dysmenorrhea is a condition that occurs at any time during menstruation that experiences pain or pain in the abdominal and pelvic area so it can interfere with activities and require treatment. This study aims to determine the effect of the effectiveness of offering papaya leaf herbal drink in reducing dysmenorrhea. The research design used in this study was a pre-experimental research design with a pre-experimental test design with accidental sampling technique. Measurement of pain intensity using pain scale measurements (Pre-Test) and final pain (Post-test using a numerical rating scale, time of incidence on the first and second day of menstruation (77%), location of lower abdominal dysmenorrhea (92%), symptoms of dysmenorrhea, namely abdominal pain (75%), moderate pain scale (48%)], and treatment was resting (63%). Based on the results of the study, subjects who were given a papaya leaf herbal drink were able to reduce the pain scale of dysmenorrhea with a large difference in pain scale reduction in the treatment group of chopped papaya leaf stew by 3,2.
Effects of Apis Mellifera, Apis Cerana, and Trigona SP on 20 M Sprint Performance K Kusnaedi; Mukti Priastomo; I Ketut Adyana; S Sukrasno
JURNAL PENDIDIKAN JASMANI DAN OLAHRAGA Vol 7, No 2 (2022): Physical Activity and Exercise for Health and Well-being
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/jpjo.v7i2.49852

Abstract

This study aimed to determine the effect of three types of honey from three different honey bee species on increasing stamina and anti-fatigue effect by examining their effects on the biochemical process in the anaerobic pathway. Tests were carried out on humans who had met the specified criteria. The method used in this study was an experimental method involving 30 healthy students. The inclusion requirements consisted of males aged 18-20 years, weight 50-70 kilograms, height 160-170 cm, normal momentary blood sugar levels 140 mg/dL, VO2max 35-40 ml/kg/min, normal blood pressure, and not having severe diseases such as diabetes, asthma, kidney failure, hepatitis, as well as other serious diseases that hinder physical activity. Volunteers had also filled out informed consent stating their willingness to participate in the research to completion. The results of this study showed that there was a change between pre and post in each groups, indicating that each honey content had a significant impact on improving the participant performance. In addition, this study found changes in the three types of honey (Apis Mellifera, Apis Cerana, Trigona SP) in the participant running performance improvement. However, there was no significant difference between the three types of honey.
Observasi Klinik Pemberian Aroma Pandan Wangi Terhadap Tekanan Darah Pasien Hipertensi Mukti Priastomo; Riska Putri Patila Sau; Jaka Fadraersada
Jurnal Sains dan Kesehatan Vol. 1 No. 10 (2018): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v1i10.98

Abstract

Daun pandan wangi memiliki aroma khas yang berasal dari minyak atsiri. Kandungan minyak atsiri pada daun pandan wangi terdiri dari 6–42% hidrokarbon sesquiterpen dan 6% monoterpen linalool dan 10% senyawa aromatik berupa 2-acetyl-1 pyrroline. Senyawa minyak atsiri daun pandan wangi memberikan efek relaksasi pada pasien hipertensi. Penelitian ini bertujuan untuk melihat karakteristik, pola pengobatan dan efek dari pemberian aroma pandan wangi terhadap tekanan darah pasien hipertensi di Puskesmas Sempaja Samarinda. Metode penelitian yang digunakan adalah metode eksperimental quasy. Prosedur dalam penelitian ini menggunakan pengukuran awal dan pengukuran akhir. Pengumpulan data karakteristik dilakukan secara retrospektif dan didapatkan persentase tertinggi dari jenis kelamin adalah perempuan sebanyak 55,36%. Usia dengan persentase tertinggi adalah usia pertengahan sebanyak 57,14%. Obat yang paling banyak dikonsumsi adalah amlodipin sebanyak 75,45%. Hasil analisis dari pemberian aroma pandan wangi sebelum dan setelah pemberian aroma terjadi penurunan pada tekanan sistol sebanyak 7,5 mmHg, pada tekanan diastol sebanyak 1,1 mmHg dan penurunan pada denyut jantung sebanyak 3,1. Kesimpulan dari penelitian ini adalah perempuan lebih banyak menderita hipertensi, usia yang paling tinggi terkena hipertensi adalah usia pertengahan dan obat yang paling banyak dikonsumsi adalah amlodipin. Hasil dari intervensi aroma dari pandan wangi dapat menurunkan tekanan darah dan denyut jantung.
Aktivitas Antioksidan dan Tabir Surya Ekstrak Etanol Tanaman Crassocephalum crepidioides (Benth.): Antioxidant and Sunscreen Activity of Ethanol Extract of Crassocephalum crepidioides (Benth.) Rolan Rusli; Ismah Nuri; Mahdyya Afiana Ramadani; Vita Olivia Siregar; Mukti Priastomo; Muhammad Faisal
Jurnal Sains dan Kesehatan Vol. 4 No. 3 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i3.1026

Abstract

Crassocephalum crepidioides (sintrong) plant has secondary metabolites such as flavonoids, saponins, steroids, and tannins which are thought to have antioxidant and sunscreen activities. Antioxidant activity of the ethanol extract of the leaves and flowers of Sintrong was measured using Uv-Vis spectrophotometry obtained IC50 values of 23.558 ppm (flowers) and 0.62 ppm (leaves), and categories as very strong antioxidants. Based on %Te and %Tp values, ethanol extract of sintrong leaves was categories as sunblock, while ethanol extract of flowers of sintrong was categories as Fast Tanning (for %Te) and for %Tp was categories as suntan standard (for 200-300 ppm) and Extra Protection (for 400-600 ppm). The SPF of the ethanol extract of the leaves and flowers of sintrong is categories as minimal protection.
Cegah Cacingan Dengan Perilaku Hidup Bersih Dan Sehat di SD Negeri 016 Samarinda Utara Jessica Merry Irawan; Widya Suci Musfirah; Aditya Fridayanti; Mukti Priastomo
Jurnal Pengabdian Masyarakat Wadah Publikasi Cendekia Vol 3 No 2 (2026): Jurnal Pengabdian Masyarakat WPC
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/jpmwpc.v3i2.1680

Abstract

Helmintiasis merupakan penyakit infeksi yang ditularkan melalui tanah (Soil Transmitted Helminths) masih menjadi masalah kesehatan masyarakat, terutama pada anak usia sekolah dasar. Kegiatan promosi kesehatan “Cegah Cacingan dengan Perilaku Hidup Bersih dan Sehat (PHBS)” bertujuan meningkatkan pengetahuan siswa mengenai bahaya cacingan dan cara pencegahannya. Kegiatan ini menggunakan desain pretest-posttest pada 27 siswa kelas V SD Negeri 016 Samarinda Utara. Edukasi diberikan melalui penyuluhan dengan media power point, leaflet, video edukasi. Analisis data dilakukan secara deskriptif menggunakan Microsoft Excel dan secara inferensial menggunakan IBM SPSS versi 27 dengan uji normalitas Shapiro-Wilk dan Uji T Berpasangan (Paired Samples Test). Hasil menunjukkan rata-rata skor pengetahuan meningkat dari 55,9 (pretest) menjadi 80,7 (posttest). Hasil Uji T Berpasangan menunjukkan nilai Sig. <0,001 yang menandakan terdapat perbedaan signifikan antara skor sebelum dan sesudah intervensi. Kegiatan promosi kesehatan ini terbukti efektif dalam meningkatkan pengetahuan siswa mengenai pencegahan cacingan melalui penerapan Perilaku Hidup Bersih dan Sehat.