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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Journal of Agromedicine and Medical Sciences ad-Dawaa : Journal of Pharmaceutical Sciences JAFP (Jurnal Akademi Farmasi Prayoga) Jurnal Katalisator Journal of Pharmaceutical and Sciences. DIVERSITAS HAYATI: Journal of Conservation and Biological Resources

Noni Rahayu Putri

Universitas Perintis Indonesia

Author-ID : 4338907

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Published : 9 Documents Claim Missing Document

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Articles

Formulation of Gel from Corn Silk Extract (Stigma maydis) and Burns Healing Activity Noni Rahayu Putri; Nessa Nessa; Yoga Ramadhana
Journal of Agromedicine and Medical Sciences Vol 7 No 2 (2021)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v7i2.20287

Corn silk (Stigma maydis) contains compounds that play a role in wound healing, such as flavonoids, saponins, tannins. This study aims to formulate a gel from corn hair extract and see its activity in healing burns. The test group was divided into four groups: group I (hot metal induction), group II (without extract ), group III (corn hair extract concentration 5%), and group IV (comparison B®), which metal induction. The parameters observed were % wound healing, epithelialization time, and histopathology. The results of the study on the average% of burns healing rate 7, 14 and 21 days, namely group I (27,92%; 62,42%; 100%), group II (35,39%; 60,16%; 100%), group III (44,05%; 63,69%; 100%) and group IV (32,81%; 66,48%; 100%). The mean time of tissue peeling epithelialization groups I, II, and III was on day 16, and group IV was on day 17. For the histopathological results, the mean score of collagen fibers, fibroblast cells, and epithelialization was respectively group I (2,2; 2,7; 2), group II (2,8; 2,9; 2), group III (3,3; 2,9; 2,7), and Group IV (3,9; 3; 3). The results of the two-way ANOVA statistical test on % burn healing (p> 0.05) and one-way ANOVA at the time of epithelialization (p> 0.05) and the histopathological score (p <0.05) showed that group III (the corn hair extract 5 %) could influence the process of healing burns. Keywords: Burns, Corn Silk Extract (Stigma maydis), % Burn Healing, Epithelialization Time, Histopathology

FORMULASI OBAT KUMUR EKSTRAK ETANOL BAWANG DAYAK (Eleutherine bulbosa (Mill. ) Urb)dan UJI EFEKTIVITAS ANTI JAMUR TERHADAP PERTUMBUHAN Candida albicans Noni Rahayu Putri; Ria Afrianti; Zulfa Desinta
Jurnal Akademi Farmasi Prayoga Vol 3 No 1 (2018): Jurnal Akademi Farmasi Prayoga
Publisher : Jurnal Akademi Farmasi Prayoga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (146.806 KB)

Telah dilakukan penelitian tentang formulasi obat kumur ekstrak etanol bawang dayak dan uji aktivitas antijamur terhadap jamur Candida albicans. Ekstrak etanol bawang dayak mengandung beberapa senyawa metabolit sekunder, dimana yang berperan sebagai antijamur adalah alkaloid, flavonoid dan fenolik. Obat kumur ekstrak etanol bawang dayak dibuat menjadi empat formula yaitu F0 (basis), F1 (ekstrak etanol bawang dayak 2,5% ), F2 (ekstrak etanol bawang dayak 5% ) dan F3 (ekstrak etanol bawang dayak 10% ). Evaluasi obat kumur meliputi pemeriksaan organoleptis, pH, stabilitas dan viskositas. Uji aktivitas antijamur sediaan obat kumur dilakukan dengan metode difusi agar dan dianalisis menggunakan ANOVA satu arah. Hasil evaluasi menunjukkan bahwa sifat fisik sediaan obat kumur memberikan hasil yang baik dan memenuhi syarat sediaan obat kumur. Hasil uji aktivitas antijamur sediaan obat kumur memberikan diameter rata – rata daya hambat sebesar F0 (11,75 mm), F1 (17,62 mm), F2 (21,8 3 mm ) dan F3 (22,33 mm).

FORMULASI SEDIAAN EYESHADOW CREAM MENGGUNAKAN EKSTRAK ETANOL UBI JALAR UNGU (IPOMOEA BATATAS L.) SEBAGAI PEWARNA Noni Rahayu Putri; Diana Agustin; Cania Mela Putri
Jurnal Akademi Farmasi Prayoga Vol 5 No 2 (2020): Jurnal Akademi Farmasi Prayoga Vo.5 No.2 Tahun 2020
Publisher : Jurnal Akademi Farmasi Prayoga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (496.424 KB)

ABSTRAK Ubi jalar ungu (Ipomoea batatas L.) merupakan salah satu jenis ubi jalar yang mengandung antosianin yang tinggi sehingga sangat baik digunakan sebagai pewarna pada sediaan kosmetika. Tujuan penelitian ini memformulasi sediaan eyeshadow cream dengan menggunakan ekstrak etanol ubi jalar ungu sebagai pewarna dan mengetahui formula eyeshadow cream yang paling disukai. Konsentrasi ubi jalar ungu yang digunakan adalah F0: 0%, F1: 8%, F2: 12% dan F3: 16%. Metode ekstraksi yang digunakan yaitu metode maserasi. Evaluasi sediaan yang dilakukan yaitu pemeriksaan organoleptis, homogenitas, uji oles, uji stabilitas, pH, tipe krim, iritasi kulit, uji kesukaan dengan metode Kruskall- Wallis. Hasil evaluasi menunjukkan bahwa tipe krim air dalam minyak (a/m), uji oles baik, stabil, sifat fisik semua formula eyeshadow cream berbentuk setengah padat, warna merah muda, bau minyak mawar, homogen, pH rata-rata dari 4,94 sampai 6,07 ,tidak menyebabkan iritasi. Hasil uji kesukaan menunjukkan bahwa sediaan eyeshadow cream yang paling disukai adalah F3. Ekstrak etanol ubi jalar ungu ( Ipomoea batatas L.) dapat digunakan sebagai pewarna dalam sediaan eyeshadow cream dan formula yang paling disukai oleh panelis yaitu F3.

Formulation of Film Soap Ethanol Extract Mesocarp of Red Watermelon (Citrullus lanatus) and Antioxidant Activity Test Noni Rahayu Putri; Tisa Mandala Sari; Rizki Aulia Wulandari
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 4 No 2 (2021)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v4i2.25172

Film soap is soap in the form of a thin layer having a thickness of 100 - 500 µm made of foaming film and plasticizer. The advantages of paper soap preparations are convenient in use, hygienic, practical, and easy to carry anywhere. Mesocarp red watermelon is a part of watermelon that contains flavonoid compounds that have antioxidant activity. The purpose of this study was to formulate the film soap of red watermelon mesocarp extract and to determine its antioxidant activity. In this study, the formulation was carried out by making four formulas with varying concentrations of ethanol extract mesocarp of red watermelon F0 = 0%; F1 = 1.5%; F2 = 2% and F3 = 3%. The evaluation was carried out in the form of organoleptic examination, pH, foam power, weight uniformity, moisture content, thickness, irritation test, stability and antioxidant activity tests. The evaluation results of the film soap from the four formulas were pH 9.29 - 9.12; weight uniformity 0.125 - 0.134 grams, water content 16.80 - 16.30%; thickness 0.14 - 0.15 mm and physically stable. The antioxidant activity of each formula was seen from the value, namely IC50F0 = 76.42µg / mL; F1 = 70.36 µg / mL; F2 = 65.14µg / mL; F3 = 62.14 µg / mL. From the research results, it can be concluded that the ethanol extract of red watermelon mesocarp can be formulated into film soap and has antioxidant activity which is included in the strong group.

UJI AKTIVITAS REPELLENT SPRAY MINYAK ATSIRI DAUN JERUK PURUT (Citrus hystrix) TERHADAP NYAMUK Culex sp. Elmitra; Noni Rahayu Putri; Dedi Nofiandi; Hanifa Sabila Afra
JURNAL KATALISATOR Vol. 8 No. 1 (2023): Jurnal Katalisator Volume 8 No. 1, April 2023
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Kaffir lime leaf (Citrus hystrix) is a plant that contains aromatic oil. The aroma is not liked by insects, so it can be used as a repellent. Kaffir lime leaf essential oil contains linalool, citronella, and beta-citronellol compounds which have biolarvicidal effects on mosquitoes. This study aims to formulate the essential oil of kaffir lime leaves in the form of a spray repellent against Culex Sp. In this study, the kaffir lime leaf essential oil formula was made with variations in concentration, namely formula 1 (10%), formula 2 (15%), and formula 3 (20%). The test parameters include organoleptic examination, pH test, stability test, viscosity test, skin irritation test and repellent activity test against Culex Sp. The spray formula with concentrations of 10%, 15% and 20% had protection against mosquitoes during 3 hours. Spray repellent formula with a concentration of 10% has a protection power of 50%, a concentration of 15% has a protection power of 75%, and a concentration of 20% has a protective power of 93.30%.The kaffir lime leaf essential oil (Citrus hystrix) can be formulated as an aromatherapy wax and the repellent activity of the kaffir lime leaf essential oil (Citrus hystrix) aromatherapy candle shows that the repellent activity increases along with the increase in the concentration of kaffir lime leaf essential oil.

SEDIAAN KRIM TABIR SURYA FRAKSI ETIL ASETAT KULIT BATANG RAMBUTAN, AKTIVITAS ANTIOKSIDANNYA Tisa Mandala Sari; Noni Rahayu Putri; Silvia Asnita Sari
JURNAL KATALISATOR Vol. 8 No. 1 (2023): Jurnal Katalisator Volume 8 No. 1, April 2023
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Research has been carried out on the determination of antioxidant activity in vitro on rambutan bark with experimental methods. The ethyl acetate fraction was obtained from the ethanol extraction of the rambutan bark from maceration. The formula was made by varying the concentration of 3 fractions, namely F0 without fraction, F1 (1%), F2 (1.5%), and F3 (2%) with organoleptic test parameters, each formula was in the form of a semi-solid, distinctive odor and different color. -different in white F0, orange F1, light brown F2 and brown F3. Homogeneity test on each homogeneous formula, viscosity test results obtained 2840cP, 2825cP, 2815cP, 2810cP for F0, F1, F2 and F3 respectively. The washing power test was found to be 32mL; 32.1mL; 30.5mL; 27.1mL for F0, F1, F2 and F3 respectively. The cream type test on each formula showed the W/A type. pH test results obtained 7,10; 7.14; 7.06; 6.97 for F0, F1, F2 and F3 respectively. Stability test on each formula showed stable results, irritation test on each formula showed that no irritation occurred. Determination of antioxidant activity using the DPPH method by looking at the IC50 value and determining the SPF value. The results of the antioxidant activity test obtained IC50 values at F0 of 108.497 ppm in the medium category, F1 at 69.23 ppm in the strong category, F2 at 61.92 in the strong category, and F3 at 61.39 in the strong category. The best formula was formula 3 with antioxidant activity of 61.39 ppm in the strong category.

Formulation and Antibacterial Activity Test of Hand Soap Gel from Ethanol Extract of Bay Leaf (Syzygium nervosum DC) Noni Rahayu Putri; Epi Supri Wardi; Arnela Sukma Ningsih; Miftahur Rahmi
DIVERSITAS HAYATI Vol. 3 No. 2 (2025): DIVERSITAS HAYATI: Journal of Conservation and Biological Resources
Publisher : UIN Sulthan Thaha Saifuddin Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30631/634vbt26

Background: Bay leaf (Syzygium nervosum DC) is one of the plants that has antibacterial activity that can be used as an active substance in hand soap gel preparations of bay leaf ethanol extract. To formulate a hand soap gel preparation from ethanol extract of bay leaf and evaluate its antibacterial activity. This study is experimental in nature. The research includes the preparation of a concentrated extract from bay leaves and its characterization, followed by the formulation of hand soap gel from the ethanol extract of bay leaves in four different concentrations: F1: 7.5%, F2: 10%, and F3: 12.5%. Evaluation of the physical quality of the formulations includes organoleptic properties, homogeneity, pH testing, viscosity testing, and stability testing. The antibacterial activity of the hand soap gel formulation is assessed using the replica method. The physical evaluation results of the hand soap gel meet the SNI standards. The average percentage decrease in the number of colonies was as follows F0 = 31.8%, F1 = 59.4%, F2 = 81.1%, F3 = 83.2% and the comparison preparation (brand B*) was 83.3%. Bay leaf ethanol extract hand soap gel is capable of inhibiting bacterial growth using the replica method.

Formulation of Body Lotion Ethanol Extract of Kepundung Bark (Baccaurea Macrocarpa (Miq.) Mull Arg.) and Antioxidant Activity Test Noni Rahayu Putri; Tisa Mandala Sari; Sri Rahma Z
Media Farmasi: Jurnal Ilmu Farmasi Vol. 22 No. 1: March 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v22i1.25872

The bark of kepundung (Baccaurea macrocarpa (Miq.) Mull Arg.) contains secondary metabolite compounds from polyphenols such as flavonoids, phenolic, terpenoids, and alkaloids, which have the potential for natural antioxidants. This research aims to evaluate of ethanol extract from kepundung bark and formulate the body lotion to test its antioxidant activity using the DPPH method. Body lotion formulas were made with variations in the concentration 0.4, 1.0, and 1.6% of ethanol extract of kepundung bark as active ingredients. The evaluation of body lotion included organoleptic, pH, homogeneity, type of body lotion, stability, viscosity, irritation, and antioxidant activity tests. The results of the physical evaluation of the body lotion meet the requirements. Namely, all formulas are homogeneous, according to skin pH, the viscosity of the preparation ranges from 2500 cP, stable, and does not irritate. The value IC50 antioxidant activity of ethanol extract of kepundung bark was 4.04 ppm. The value IC50 antioxidant activity body lotion at F1, F2, and F3 respect 41.91, 36.98, and 33.13 ppm. The result showed the best formula is F3 with a value IC50 33.13 ppm. Based on the study, the ethanol extract of depending bark and the body lotion has very strong antioxidant activity.

Aktivitas Hepatoprotektor Fraksi Polar n-Butanol Rambut Jagung (Zea mays L.) Terhadap Tikus Putih Jantan yang Diinduksi Paracetamol Nessa Nessa; Noni Rahayu Putri; Iim Mutmaina
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1277

Corn silk is a part of the corn plant that is known to contain beneficial chemical compounds, including flavonoid compounds that have antioxidant activity and have the potential as hepatoprotective compounds that can protect the liver from damage caused by free radicals. The purpose of this study was to determine the hepatoprotective effect of the polar fraction of corn silk on male white rats induced by paracetamol. The animals used were 25 male white rats divided into 5 groups, namely group 1 (Negative control), group 2 (positive control) induced by toxic doses of paracetamol, and groups 3, 4, 5 polar fractions of corn silk doses (200, 400, 800 mg/kgBW). The measurement parameters were SGOT-SGPT levels, liver organ weight ratio, and histopathological examination of the liver. The data obtained were analyzed descriptively and statistically with two-way ANOVA followed by Duncan's test. The results of observations of SGOT enzyme levels on days 7 and 14 were group 1 (18.5 and 20.5 U/L), group 2 (50.5 and 113.75 U/L), group 3 (21.5 and 45.25 U/L), group 4 (23.25 and 83.75 U/L), group 5 (26.5 and 105.75 U/L). SGPT enzyme levels on days 7 and 14 were group 1 (39.75 and 42 U/L), group 2 (70.25 and 82.25 U/L), group 3 (42.5 and 48 U/L), group 4 (46.26 and 64.75 U/L), group 5 (48.75 and 70.25 U/L). The results of histopathological observations with score values of group 1 (0), group 2 (4), group 3 (1), group 4 (3), group 5 (3). Based on the research results obtained, it can be concluded that the polar fraction of corn silk has the most effective hepatoprotective activity at the lowest dose of 200 mg/kgBW with the observation results closest to the negative control for each parameter.

Co-Authors Arnela Sukma Ningsih Cania Mela Putri Dedi Nofiandi Diana Agustin Diana Agustin Elmitra Hanifa Sabila Afra Iim Mutmaina Khairatun Nisa Miftahur Rahmi Nessa Nessa Ria Afrianti Rizki Aulia Wulandari Silvia Asnita Sari Sri Rahma Z Tisa Mandala Sari Wardi, Epi Supri Yoga Ramadhana Zulfa Desinta

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