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All Journal BALI MEDICAL JOURNAL (BMJ) Medula Window of Health : Jurnal Kesehatan Alami Journal (Alauddin Islamic Medical) Journal Al-sihah: The Public Health Science Journal International Journal of Nursing and Health Services (IJNHS) Review of Primary Care Practice and Education (Kajian Praktik dan Pendidikan Layanan Primer) Nursing Arts Journal of International Conference Proceedings Strada Jurnal Ilmiah Kesehatan (SJIK)
Armyn Nurdin
Universitas Hasanuddin Makassar
Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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ANTI-PLASMODIUM FALCIPARUM IN VITRO ACTIVITY OF CALOPHYLLUM BICOLOR EXTRACT: Morphology and Ultra Structure Kaseke, Martha Marie; Hadju, Veny; Karim, Syafruddin; Nurdin, Armyn
BALI MEDICAL JOURNAL Vol 4 No 3 (2015)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (331.546 KB)

Abstract

Background: Anti-malarial resistance of Plasmodium, such as chloroquine becoming a health problem worldwide. This research aims to evaluate the in vitro anti-plasmodium activity of hexane fraction extract of Calophyllum bicolor (C. bicolor) against culture of Plasmodium falciparum (P. falciparum) 3D7 and determine its inhibitor concentration of 50% (IC50); to observe the microscopic changes of P. falciparum after exposed to the hexane fraction of C. bicolor extract and to observe the ultra structure changes of P. falciparum 3D7 after being exposed to hexane fraction of C. bicolor extract. Method: This research applied quasi experimental with post-test only control group design. Anti malarial activity test of hexane fraction of C. bicolor extract towards Plasmodium falciparum 3D7 2% was undertaken over 48 hours with in vitro incubation technique. The level of parasitemia was observed using binocular optical microscope with 1000x magnification by counting the infected erythrocytes with Giemsa color technique. Then it was analyzed to determine the level of inhibitor concentration of 50% (IC50) of the C. bicolor extract. The next step is to observe the changes of parasite’s morphologic and ultra structure after the 24 and 48 hours incubation of the parasite P. falciparum 3D7 with hexane fraction of C. bicolor, IC50. Then, the morphologic change of P. falciparum 3D7 was observed with optical binocular microscopy and the ultra structure changes with Transmission Electron Microscopy (TEM). The changes of morphologic and ultra structure were analyzed qualitatively. Results: The research revealed that hexane fraction of the C. bicolor extract inhibited the growth of the parasite P. falciparum 3D7 with the value of -49.00±2.54, 12.53±3.13, 23.01±1.10, 27.68±4.23, 48.65±18.71, 70.82±4.67, 80.52±6.17% with the hexane extract concentration of 0, 0.001, 0.01, 0.1, 1, 10, 100, and 1000 µg/mL. This research also found that the inhibitor concentration of 50% (IC50) of hexane fraction of C. bicolor extract was 3.94 µg/mL in 10-7 which could change the morphologic and ultra structure of P. falciparum 3D7. There were several changes in morphology of the parasite over 24 hour incubation compared with the control group, i.e. the nucleus of young tropozoid became thicker, darker, and smaller; the skizon were condensate, thicker, darker, karyorrhexis and demolition of membrane. Hexane fraction of C. bicolor extract also changes the ultra structure over 24 hour incubation, i.e. vacuole membrane boundary and hemozoin were unclear. Over 48 hours of incubation the nucleus and cytoplasm bigger than those in the control group. Conclusion: Hexane fraction of the C. bicolor extract showed a strong anti plasmodium activity towards the in vitro culture of P. falciparum 3D7 at the level of (IC50) 3.94 µg/mL. The Hexane fraction of C. bicolor extract could change the morphology and ultra structure of P. falciparum 3D7 in vitro.
Faktor Determinan Kesiapsiagaan Perawat Terhadap Bencana Gunung Meletus (Gamalama) di Puskesmas Wilayah Kerja Dinas Kesehatan Kota Ternate Hakim Husen, Abd; Kaelan, Cahyono; Nurdin, Armyn; J. Hadi, Anto
Window of Health : Jurnal Kesehatan Vol. 3 No. 2 (April, 2020)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (289.013 KB) | DOI: 10.33368/woh.v0i0.313

Abstract

Puskesmas is part of the government and is obliged to perform its functions in disaster preparedness. This study aimed to determine the description and the relationship of determinant factors of nurse preparedness to the eruption of Mountain Gamalama at the working area of the Health Center in ​​Ternate City Health Office. The research used the combined research method (Mixed Method), which was the combination between the quantitative method and the qualitative method. The research samples included all the nurses in the Health Center of the working area of the Health office of Ternate City comprising 41 people. The data analysis was conducted using the Chi-square test for quantitative research. The Knowledge variable was p=0,05, and the skill variable was p= 0,171. The related to the preparedness. Meanwhile, the qualitative research was in the form narration of the interviews with the respondents who had low skills because of the little training and stimulation about the calamity.
POTENSI YANG HILANG BERDASARKAN HEALTH RELATED QUALITY OF LIFE PADA PENDERITA KANKER PAYUDARA DI MAKASSAR SULAWESI SELATAN Muhammad Basir Palu; Andi Armyn Nurdin
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 1 (2014)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (103.888 KB) | DOI: 10.46496/medula.v2i1.241

Abstract

Kanker payudara  (KPD)  merupakan  jenis  kanker  yang  paling  sering  ditemukan  pada wanita usia pertengahan. Selain penderitaan fisik dan fungsional, wanita dengan KPD sering mengalami  gangguan atau   penurunan  kualitas  hidup. Penurunan   kualitas  hidup  tersebut dapat dinilai  dengan  menentukan Health  Related  Quality  of  Life  (HRQOL)yang mengutamakan penilain tentang  kesehatan  fisik,  status  psikologi,  hubungan  sosial,  tingkat kemandirian  dan  spiritual. Tujuan penelitian  untuk mengetahui  potensi  yang  hilang berdasarkan Health  Related  Quality  of  Life  (HQROL) pada  penderita  kanker  payudara   di Kota Makassar. Metode penelitian ini merupakan survey analitik secara studi potong lintang (cross  sectional  study) dengan  melakukan  eksplorasi pada  30  kasus  Kanker  Payudara berdasarkan Health Related Quality of Life (HQROL)di Kota Makassar. Hasil penelitian ini menunjukkan sebagian  besar  (66.7%) mengalami  gangguan melakukan  aktivitas  harian, namun  hanya  sebagian  kecil  (33%)  yang  meninggalkan  pekerjaannya. Sebagian  besar (66.7%)  penderita masih  dapat  melakukan  kegiatan  olah  raga  ringan. Kebanyak  responden merasakan  nyeri yakni sebanyak  22  orang  (73.33%) dan  sebanyak 16  orang  (53.33%) meninggalkan  pekerjaan  karena  rasa  nyeri. Responden yang  memiliki  rasa tidak  nyaman sebanyak 18 orang (60%) dan sebagian besar responden meninggalkan pekerjaan disebabkan adanya  rasa  tidak  nyaman  sebanyak  22  orang  (73.33%). Sebanyak   60%  sampai 86.67% mengalami  gangguan  kesehatan  psikologis  berupa  gangguan  stress  emosional  dan meninggalkan  pekerjaan  karena  stress. Tingkat  kemandirian  pasien  KPD  cukup  tinggi, sebagian  besar  responden  yakni  22  orang  (73.33%)  tidak  membutuhkan  orang  lain  untuk merawat  diri  dan  aktivitas  gerak. Sebagian  besar  gangguan  dalam  hubungan  sosial  bagi responden  adalah  gangguan berinteraksi  dengan  masyarakat  sebanyak  18  orang  (60%). Hanya sebagian kecil responden mengalami gangguan spiritual yakni berkisar antara 13.33% -33.33%. Penilaian  berdasarkan EUQOL  yang  berhubungan  dengan mobility,  self  Care, usual activities, pain and discomfort, anxiety and depression. Sebagian besar penderita KPD (60-67%) mengalami beberapa masalah ringan/sedang, hanya sebagian kecil yakni berkisar 0-13%  mengalami  masalah  besar. Kesimpulan penelitian  adalah  sebagian  besar  penderita KPD  mengalami  potensi  yang  hilang  dalam  hal   gangguan  aktivitas  harian,  rasa  nyeri, gangguan   stress  emosional  ringan  dan sedang  (kecemasan  dan  depresi) dan  gangguan berinteraksi dengan masyarakat. Namun penderita KPD masih memiliki kemandirian dalam perawatan diri dan aktivitas gerak, serta adanya peningkatan kesadaran spiritual. Kata kunci: Potensi yang hilang, kualitas hidup (HRQOL)
THE ROLE OF ENDORPHIN HORMONES AS PREDICTORS OF PREGNANCY ANXIETY Putriatri Krimasusini Senudin; Saidah Syamsuddin; Andi Armyn Nurdin
International Journal of Nursing and Health Services (IJNHS) Vol. 2 No. 3 (2019): International Journal of Nursing and Health Services (IJHNS)
Publisher : Alta Dharma Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (211.292 KB) | DOI: 10.35654/ijnhs.v2i3.107

Abstract

Pregnancy anxiety is a common problem with a prevalence of 14-54% and is the highest in the third trimester. Pregnancy anxiety is associated with neurotransmitter dysregulation and endocrine changes in the Hypothalamus Pituitary Adrenal (HPA) axis pathway through the increase of synthesis and the release of corticotropin-releasing hormone (CRH), Adrenocorticotropic Hormone (ACTH) and cortisol to suppress endorphin hormone production. This study aims to determine the relationship of endorphin hormone levels to pregnancy anxiety. This study was an observational study using a cross-sectional approach to 57 pregnant women. The anxiety level was measured by using the Hamilton Anxiety Rating Scale (HARS) and the ELISA kit with plasma specimens was employed to examine the endorphin hormone levels. The results showed that endorphin hormone levels acted as predictors of pregnancy anxiety (p = 0,000). Keywords: Anxiety, Pregnancy, Endorphin
PERSEPSI PASIEN TERHADAP FAKTOR YANG MEMPENGARUHI RUJUKAN PASIEN KECELAKAAN LALU LINTAS Muhammadong Muhammadong; Cahyono Kaelan; Armyn Nurdin
Nursing Arts Vol 14 No 2 (2020): NURSING ARTS
Publisher : Jurusan Keperawatan Poltekkes Kemenkes Sorong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36741/jna.v14i2.118

Abstract

Salah satu bentuk pelaksanaan dan pengembangan upaya kesehatan dalam Sistem Ketahanan Nasional (SKN) adalah rujukan upaya kesehatan. Penelitian ini bertujuan untuk menganalisis faktor yang mempengaruhi tingginya angka rujukan pasien kecelakaan lalu lintas di IGD RSUD Pangkep ke rumah sakit Rujukan di Makassar. Desain penelitian ini adalah korelasi dengan rancangan cross sectional dengan jumlah sampel 32 responden. Teknik pengambilan sampel secara Non Random Sampling (Purposive Sampling). Analisis bivariat digunakan untuk melihat faktor yang mempengaruhi tingginya angka rujukan. Dari hasil penggabungan cells dengan menggunakan hasil uji statistik Somers’D diperoleh nilai significancy sebesar 0,006 < 0,05 untuk SDM, yang menunjukkan bahwa hubungan bermakna, dimana nilai korelasi sebesar 0,507 yang menunjukkan bahwa korelasinya kuat, dibandingkan sarana dan kegawatdaruratan. Oleh karena itu, rumah sakit sebaiknya menambah sumber daya manusia dalam hal ini tenaga spesialis dokter ortopedi dan traumatologi dan anasthesi, menyediakan sarana berupa rumah dinas kepada dokter spesialis dan memberikan insentif, membuat SOP tentang rujukan pasien berdasarkan diagnosa medisnya dan melakukan kerjasama dengan fakultas kedokteran agar menempatkan dokter residence di rumah sakit pangkep, terutama pada hari libur dan harihari besar lainnya.
New Civilization in the Post-Covid-19 Health World & Lesson Learned from the Netherlands Armyn Nurdin; Tjay Tan; Isti Ilmiati Fujiati
Review of Primary Care Practice and Education (Kajian Praktik dan Pendidikan Layanan Primer) Vol 3, No 3 (2020): September
Publisher : Faculty of Medicine, Public Health, and Nursing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/rpcpe.62771

Abstract

New Civilizations in the Post-Covid-19 World Health There  are  several  possibilities  that  will happen  after  the Covid-19  outbreak  ends.  This  is  the  other  side  of  the Covid-19 pandemic.  There  is  a  term  called  see  the  un- seen, or seeing something before it happens. An illustrative example is that everyone sees the apple falling down, but only one person sees why or what causes the apple to fall down. This  is  Isaac  Newton.  Based  on  this phenomenon, the formula for the gravitational force or the gravitational force of the earth is triggered. This paper focuses on what might happen in the future.Indeed, the earth repairs itself in its own way, and that is for the benefit of mankind. The Covid-19 outbreak that is currently happening is a very positive thing for human life. Under the earth there are shifts in the earth’s plates which cause tectonic earthquakes. What is the goal? The aim is to stabilize the earth so that an asteroid collision does not occur. There is a plague on earth, what does it mean? Its meaning is  to  improve  human  life.  So,  let’s interpret  the  current outbreak as something positive. Previously in Europe, there were millions of deaths due to PES disease. At that time, most farmers died, so the land owners were short of labor. What is the meaning? First, farmers have a high bargaining position. Second, after the plague occurred, then there was the collapse of feudalism. In the past, peasants worked in a kind of forced labor. Then the modern economic system was  born.  It was  started  at  that  time  when  farmers  were paid in cash which had never happened before. This was the beginning of the growth of the modern economic system2. 
Penatalaksanaan Kanker Prostat Andi Armyn Nurdin
Alami Journal (Alauddin Islamic Medical) Journal Vol 1 No 1 (2017): JULY
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (299.955 KB) | DOI: 10.24252/alami.v1i1.4210

Abstract

Kanker prostat terjadi ketika sel-sel prostat tumbuh lebih cepat daripada kondisi normal sehingga membentuk benjolan atau tumor yang memiliki keganasan.Kanker ini terjadi pada pria terutama yang berusia di atas 65 tahun. Kanker prostat merupakan penyebab kematian akibat kanker No 3 pada pria dan merupakan penyebab utama kematin akibat kanker pada pria diatas 74 tahun. Kanker prostat jarang ditemukan pada pria berusia kurang dari 40 tahun. Seperti halnya kanker lain, penyebab kanker prostat tidak diketahui, usia lanjut, faktor keturunan, ras, dan paparan logam cadminum menjadi pemicu kanker ini. Pertumbuhan kanker prostat seringkali sangat lambat, bisa tidak menimbulkan gejala selama bertahun-tahun.Dengan semakin membesarnya kanker, keluhan mulai muncul karena desakan pada uretra menimbulkan iritasi atau menyumbat aliran air seni. Biasanya kanker prostat berkembang secara perlahan dan tidak menimbulkan gejala sampai kanker telah mencapai stadium lanjut.Kadang gejalanya menyerupai BPH, yaitu berupa kesulitan dalam berkemih dan sering berkemih. Gejala tersebut timbul karena kanker menyebabkan penyumbatan parsial pada aliran air kemih melalui uretra. Kanker prostat bisa menyebabkan air kemih berwarna merah (karena mengandung darah) atau menyebabkan terjadinya penahanan air kemih mendadak. Setelah kanker menyebar, biasanya penderita akan mengalami anemia. Kanker prostat juga bisa menyebar ke otak dan menyebabkan kejang serta gejala mental atau neurologis lainnya. 
Identification of Phytochemicals, Antioxidant Activity Using DPPH Method (1.1=Diphenyl-2-Picrylhydrazyl), Toxicity Using Brine Shrimp Lethality Test of Diplazium esculentum Tea Habibi Habibi; Suryani As’ad; Armyn Nurdin; Agussalim Bukhari
Journal of International Conference Proceedings Vol 5, No 1 (2022): 2022 Malang ICPM Proceeding
Publisher : AIBPM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32535/jicp.v5i1.1453

Abstract

Vegetable fern/pakis/paku (Diplazium esculentum) contains active compounds such as total phenols, steroids, triterpenoids, flavone amino acids, and flavonoids, which are rich sources of medically necessary phytochemicals. This study aimed to determine the potential antioxidant content of pakis (Diplazium esculentum) tea. The research methods used included the antioxidant test procedure (IC50), DPPH method, phytochemical procedure, and BSLT procedure. The results of the phytochemical test showed a positive (+) value on the alkaloid, flavonoid, saponin, and phenolic test. The DPPH test showed 130.38468, 131.1340, 131.5681 ppm with an average value of 131.0289 ppm; meanwhile, moderate antioxidant activity and BSLT testing showed LC50 of 9817.479 ppm, where the tea was found not toxic since the LC50 value <1000 ppm. Based on the findings, the brewed vegetable fern/pakis (Diplazium esculentum) contains alkaloids, flavonoids, saponins, and phenolics based on phytochemical testing, potential as a non-toxic antioxidant source according to DPPH and BSLT tests. Diplazium esculentum is a vegetable that contains antioxidants and is safe for consumption.Keywords: Antioxidant activity, BSLTDiplazium esculentum, DPPH, Phytochemicals
Webinar Panelist RPCPE Serial Response to Pandemic Covid-19 Hari Kusnanto Josef; Dhanasari Vidiawati; Elsa Pudji Setiawati; Mariatul Fadilah; Armyn Nurdin; Syarhan Syarhan; Sintak Gunawan; Mora Claramita
Review of Primary Care Practice and Education (Kajian Praktik dan Pendidikan Layanan Primer) Vol 5, No 2 (2022): July
Publisher : Faculty of Medicine, Public Health, and Nursing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/rpcpe.74818

Abstract

Relaxation of PSBB Policy from the Perspective of Community Medicine and Epidemiology in IndonesiaWhen the government will do something meaningful and full of uncertainty, such as relaxation of the PSBB, it needs to be done based on a plan with uncertainty, namely scenario planning. In scenario development, four stages must be carried out, namely identifying the driving forces and critical uncertainties. Some scenarios then create a path for how a plan will travel.
Care Seeking Behavior For Pregnant and Women Giving Birth During the Covid-19 Pandemic Rosdianah Rosdianah; Yusril Ihsanul Mukarram; Andi Armyn Nurdin
Al-Sihah : The Public Health Science Journal Volume 14, Nomor 2, July-December 2022
Publisher : Program Studi Kesehatan Masyarakat UIN Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-sihah.v14i2.32925

Abstract

The total number of maternal and child mortality in Indonesia annually has not yet reached the target set by World Health Organization. This figure is influenced by maternal compliance to perform antenatal care checks. The research aimed to investigate the behavior patterns of seeking help for pregnant and giving birth during the Covid-19 pandemic. The research design was observational with a cross-sectional study design. The population in this study was selected using the consecutive sampling method based on inclusion and exclusion criteria. Within this approach, 51 samples were obtained in Gowa Regency, to whom questionnaires were distributed to get further data. As seen from the research results, 50 samples (98%) performed antenatal care checks every month, while only 1 sample (2%) did not do antenatal care checks regularly every month. Regarding mothers' knowledge of the Covid-19 pandemic, the data revealed that 33 samples had sufficient knowledge, 7 samples had good knowledge, and the rest, 11 samples, had less knowledge related to such a case. The pattern of care-seeking behavior of pregnant and giving-birth mothers during the pandemic has not changed from the period before the pandemic and pregnant women still routinely check their pregnancy every month.
Co-Authors Abd Hakim Husen Agussalim Bukhari Bilwalidayni Ikbal Cahyono Kaelan Cahyono Kaelan Cahyono Kaelan, Cahyono Dhanasari Vidiawati Din Syafruddin Elsa Pudji Setiawati Femi Marsya Andris Fujiati, Isti Ilmiati Habibi Habibi Hadi, Anto J. Hari Kusnanto Josef Isra Wahid Mariatul Fadilah Martha Marie Kaseke Mora Claramita Motoyoshi Mogi Muhammad Basir Palu Muhammadong Muhammadong Nur N. Noor Putriatri Krimasusini Senudin Rosdianah Rosdianah Saidah Syamsuddin Sintak Gunawan Suryani As’ad Syafruddin Karim, Syafruddin Syarhan Syarhan Tjay Tan Toshihiko Sunahara Veny Hadju, Veny Yusril Ihsanul Mukarram