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POTENSI EKSTRAK METANOL DAUN KAPUR (Harmsiopanax aculeatus, Harms) SEBAGAI OBAT ANTIMALARIA Wijaya, Jefry; Salenussa, Jusuf; Marantika, Jacky
Program Kreativitas Mahasiswa - Penelitian PKM-P 2013
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

Kapur plant (Harmsiopanax aculeatus Harms) is traditionally used by Mollucans to treat malaria disease. Squeezed of young leaves which is dropped on the eye of sufferer is the way of its treatment. This research is aimed to assay haem polymerization inhibition activity, cytotoxic activity toward vero cells and to analysis chemical secondary metabolit of compound content on methanol extract of the old kapur leaves. Dried powder of kapur leaves (1 kg) is extracted by maceration technique using methanol solvent obtained 95,85g (9,59%) of methanol extract. Those extract which assayed haem polymerization inhibition on activity by Bassilico et al. (1998) method is shown IC50 values of 9410,93 µg/mL. Cytotoxic test toward vero cells using MTT assay, Kasugai et al. (1983) is shown that IC50 values is 9402,81 µg/mL. Phytochemical analysis by spray and visible reagent shown of flavanoids, phenolic, saponin an antraquinones compound. Keyword: Harmsiopanax acuelatus Harms, haem polymerization inhibition activity, cytotoxic activity, vero cell, phytochemical.
POTENSI EKSTRAK HEKSAN DAUN KAPUR (Harmsiopanax aculeatus, Harms) SEBAGAI OBAT ANTIMALARIA Salenussa, Jusuf; Wijaya, Jefry; Labetubun, Colincie Natalia; Belseran, Stenly Erwin
Program Kreativitas Mahasiswa - Penelitian PKM-P 2014
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (290.045 KB)

Abstract

Kapur plant (Harmsiopanax aculeatus, Harms) is traditionally used by Mollucans to treat malaria disease. Squeezed of young leaves which is dropped on the eye of sufferer is the way of its treatment. This research is aimed to assay haem polymerization inhibition activity, cytotoxic activity toward vero cells and to analysis chemical secondary metabolit of compound content on hexane extract of the old kapur leaves. Dried powder of kapur leaves (1 kg) is extracted by maceration technique using hexane solvent obtained 24.34g (2.43%) of hexane extract. Those extract which assayed haem polymerization inhibition on activity by Bassilico et al. (1998) method and cytotoxic test toward vero cells using MTT assay. Probit analysis has showing us that hexane extract of ripe kapur leaves were inhibit haem polymerization actively with IC50 in the amount 59.473 µg/mL and were not toxic toward normal cells with IC50 in the amount 1270.746 µg/mL. Phytochemical analysis by spray and visible reagent shown of steroid compound. Keywords:  Harmsiopanax acuelatus Harms, haem polymerization inhibition activity, cytotoxic activity, vero cell, phytochemical
PENGEMBANGAN MODUL INTERAKTIF (E-MODUL) BERBASIS FLIPBOOK PADA MATA KULIAH DASAR-DASAR KIMIA ORGANIK MATERI ASAM KARBOKSILAT Wijaya, Jefry; Lokollo, Lita
Molluca Journal of Chemistry Education (MJoCE) Vol 14 No 1 (2024): MJoCE
Publisher : Program Studi Pendidikan Kimia, FKIP, Universitas Pattimura (Chemistry Education Study Program, Faculty of Teacher Training and Educational Sciences, Pattimura University)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/MJoCEvol14iss1pp38-46

Abstract

Penelitian ini bertujuan untuk: (1) menghasilkan produk e-modul interaktif berbasis Flipbook Dasar-Dasar Kimia Organik; (2) mengetahui tingkat kelayakan dan respon mahasiswa terhadap e-modul Dasar-Dasar Kimia Organik. Metode yang digunakan dalam penelitian ini adalah metode penelitian dan pengembangan (Research and Development, R&D). Subjek uji coba dalam penelitian ini adalah 33 mahasiswa Semester III Program Studi Pendidikan Kimia FKIP Universitas Pattimura. Teknik pengumpulan data dan instrumen penelitian yang digunakan adalah teknik wawancara, lembar validasi dan angket respon mahasiswa. Teknik analisis data yang digunakan dalam penelitian ini adalah analisis deskriptif untuk mendeskripsikan atau menggambarkan data yang telah terkumpul. Hasil penelitian menunjukkan bahwa e-modul Dasar-dasar Kimia organik yang dihasilkan dapat diakses secara online dan offline. E-modul ini dapat digunakan sebagai sumber belajar baik secara mandiri maupun dalam proses pembelajaran. Produk e-modul Dasar-dasar Kimia organik yang dihasilkan memperoleh penilaian layak dari hasil validasi ahli materi dan ahli media, dengan nilai rata-rata 3,6. Uji coba produk e-modul pada mahasiswa memperoleh respon positif yang artinya e-modul ini dapat diimplementasikan dalam pembelajaran.
PENGARUH SELF-ORDER KIOSK DAN QRIS TERHADAP KEPUASAN PELANGGAN (STUDI KASUS MCDONALD’S BANDAR LAMPUNG) Wijaya, Jefry; Narundana, Vonny Tiara
Jurnal Manajemen dan Profesional Vol. 6 No. 2 (2025): Jurnal JPRO
Publisher : Program Studi Manajemen Institut Teknologi dan Bisnis Asia Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32815/jpro.v6i2.2558

Abstract

Salah satu restoran cepat saji yang popular di Indonesia adalah McDonald’s. Penelitian ini bertujuan untuk mengeksplorasi dan menganalisis dampak dari Self-Order Kiosk dan QRIS terhadap tingkat Kepuasan Pelanggan di restoran McDonald’sBandar Lampung secara parsial dan simultan.Sebanyak 140 partisipan berkontribusi dalam penelitian ini, yang dipilih dengan menggunakan rumus Hair serta metode Purposive Sampling. Metode yang digunakan dalam temuan ini mencakup pengujian validitas, pengujian reliabilitas, analisis statistik deskriptif, analisis regresi linear berganda, pengujian hipotesis (yang meliputi Uji T dan Uji F), serta pengujian koefisien determinasi. Hasil penelitian menyatakan Self-Order Kiosk dan QRIS mempengaruhi secara positif pada Kepuasan Pelanggan baik secara parsial dan simultan
Analysis of Diazo Quinolinone Complexes with Various Metal Ions Rumengan, Stefan Marco; Ummah, Khoirotul; Mardliyah, Ana; Wijaya, Jefry; Tambalean, Febrindah Ester; Tengker, Soenandar Milian; Saiya, Abdon; Karundeng, Marlina; Paat, Vlagia Indira
Stannum : Jurnal Sains dan Terapan Kimia Vol 6 No 1 (2024): April 2024
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v6i1.4882

Abstract

Quinolones are heterocyclic compounds that are important in medicine and materials for DSSCs or OLEDs. One thing that is rarely studied is the ability to detect metal ions. Diazo groups have an important role in forming complexes with metal ions. This research aims to obtain initial information regarding the metal detection capabilities of diazo quinolinone compounds. The compound 7-[(2,4-dihydroxyphenyl)diazenyl]-4-methyl-2-quinolinone is the test target. Tests were carried out with various metal ions in MeOH. Next, the wavelength of the complex was determined using a UV-Vis spectrophotometer. The results of complex analysis of Compound 2 with various metal ions show the potential to be an indication of the presence of metal ions.
Prevalence of Amputation Events in Diabetic Ulcer Patients at Tarakan District Hospital Ruchika, Ruchika; Oktavia, Eva; Kartadinata, Riki; Wijaya, Jefry; Ratu, Livia Lita
Jurnal MedScientiae Vol. 2 No. 1 (2023): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i1.3097

Abstract

Diabetes mellitus (DM) is a condition of increased blood sugar levels that can increase the risk ofmacrovascular and microvascular damage, thereby reducing the quality of life of the sufferer.Objective is to determine the prevalence, demographic data and clinical data from diabetic ulcerpatients who performed amputations at Tarakan Hospital for the period of 2018. The researchsubjects were patients with diabetes mellitus who had diabetic ulcers who were amputated at TarakanHospital for the period 2018. Data on the results of amputation of diabetic ulcer patients werecollected and the researchers set aside forms that included exclusion criteria. Furthermore, dataprocessing using SPSS statistical programs and Microsoft excel. The total sample was obtained by 8samples with amputations from 398 samples at the Tarakan Hospital for the period 2018. The mostages were 17-60 (62.5%) as many as 5. The highest gender was female (62.5%) as many as 5 people.Smoking only 12.5% ​​as much as 1 person. Dyslipidemia obtained 50% as many as 4 people.Hypertension was obtained 62.5% as many as 5 people. The longest duration of suffering from DMwas > 10 years (62.5%) as many as 5 people. Obesity who experienced diabetic ulcer amputation asmany as 4 people (2.0%). Patients aged 17-60 experienced the most amputation of diabetic ulcers.Female, dyslipidemia, hypertension, duration of DM > 10 years, obesity