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THE EFFECT OF PLYOMETRICS TRAINING ON LEG MUSCLE STRENGTH OF MEDICAL STUDENTS IN DIPONEGORO UNIVERSITY Nur Azzahra Permata Putri Ismail; Edwin Basyar; Darmawati Ayu Indraswari; Marijo Marijo
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 8, No 4 (2019): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Introduction : Strength is the ability to excert force, which can resist external resistance and its purpose as a basis for human movements. Strength also can be a standard for measuring someone’s performance. Plyometrics training known as an exercise that can increased muscle strength. Great muscle strength can lead to great muscle endurance so that the person will become healthier and will not get tired easily. However, there’s still no further study that measured leg muscle strenght on medical students after given plyometrics training treatment. Methods : Intervention of the study was plyometrics training for 6 weeks. This study was a quasi-experimental with pre-test (before training), middle-test (after four weeks training), and post-test (after six weeks training). The subjects were 28 (15 to 25-year old) male medical students of Diponegoro University divided into 2 groups with 14 samples for each group: control group and treatment group. Muscle strength were measured by leg dynamometer. The results were analyzed using SPSS. Results : The muscle strength which measured by leg dynamometer improved among subjects who did plyometrics training. The significant results (P = <0,05) found on middle-test and post-test proved that plyometrics training affects the enhancement of leg muscle strength. Conclusions : Plyometrics training for 6 weeks proved to increase leg muscle strength of medical students in Diponegoro University.Keywords: Plyometrics Training, Strength, Leg Dynamometer

KESESUAIAN TIPE TENSIMETER AIR RAKSA DAN TENSIMETER PEGAS TERHADAP PENGUKURAN TEKANAN DARAH PADA USIA DEWASA Rosinondang Deolita Simamora; Edwin Basyar; Ari Adrianto
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 6, No 2 (2017): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Latar Belakang: Sistem sirkulasi dalam tubuh disusun oleh banyak faktor salah satunya tekanan darah. Tekanan darah dibedakan menjadi tekanan sistolik dan diastolik. Tekanan darah dapat diukur dengan alat tensimeter. Tensimeter air raksa telah digunakan menjadi gold standart untuk pengukuran tekanan darah. Namun terdapat masalah utama dalam penggunaan tensimeter ini yaitu bahwa air raksa merupakan salah satu dari tiga unsur yang beracun di bumi, sehingga dapat memberikan dampak negatif terhadap kesehatan dan lingkungan. Sebagai alternatif, beberapa institusi mulai beralih dari tensimeter air raksa ke tensimeter pegas.Tujuan: Penelitian ini bertujuan untuk membuktikan adanya kesesuaian tipe tensimeter air raksa dan tensimeter pegas terhadap pengukuran tekanan darah.Metode: Penelitian ini merupakan penelitian uji kesesuaian alat dengan rancangan penelitian cross-sectional menggunakan uji reliabilitas Cohen Kappa. Pengambilan data didapat dari 50 subjek dengan melakuan 3 kali pengukuran setiap subjek.Hasil: Rerata tekanan sistolik tensimeter air raksa 108,22 dan tensimeter pegas 108,4, sedangkan untuk tekanan diastolik tensimeter air raksa 73,92 dan tensimeter pegas 72,66. Uji reliabilitas menunjukkan bahwa kesesuaian tekanan sistolik kedua alat tersebut yaitu sangat baik (κ = 0,872) dan kesesuaian tekanan diastolik yaitu baik (κ = 0,629).Kesimpulan: Terdapat kesesuaian antara tipe tensimeter air raksa dan tensimeter pegas sehingga kedua alat tersebut dapat digunakan untuk saling menggantikan satu sama lain dalam pengukuran tekanan darah.

Factors Associated with Survival Rate in Biliary Atresia Patients Following Kasai Surgery Prasetyo, Agung Aji; Basyar, Edwin; Wibisono, Agoes; Wardhani, Avriana Pety; Rachmawati, Banundari; Riwanto, Ignatius
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 2 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i2.1059

Introduction: Biliary atresia is the most frequent cause of obstructive jaundice leading to liver fibrosis, end-stage liver disease, and death. Kasai surgery offers a bridge to attenuate liver fibrosis progression through reconstruction of the biliary system. The success of the Kasai procedure depends on the presence of jaundice, age at the time of surgery, clay-colored stool, and bilirubin counts. Aim: This study aimed to investigate and predict the death incidence of Biliary atresia patients following Kasai Surgery in our institution. Method: We conducted a case-control study from March 2020 to January 2022 at Kariadi General Hospital, Semarang, Indonesia. We collected data related to gender, age at surgery, albumin level pre and post-surgery, total and direct bilirubin before and after surgery, and the presence of ascites. Bivariate analysis using the Chi-Square test with OR (95% CI) was performed to analyze the risk factors in BA patients following the Kasai procedure. Results: 19 patients with biliary atresia underwent the Kasai procedure with a survival rate of 68.4%. Bilirubin levels ≥10 mg/dL before (p=0.033, OR 11.25) and after (p=0.025, OR 11.00) the Kasai procedure, and the presence of ascites (p=0.005) were significant factors associated with mortality cases. However, a combined multivariate analysis of these factors did not show any significant relationship with outcomes. Conclusion: Bilirubin exceeding 10 mg/dL before and after the Kasai procedure and the presence of Ascites was a marker for poor outcomes for biliary atresia patients following the Kasai procedure

Effect of Genistein-rich Edamame Extract on Eosinophil-Lymphocyte Ratio Pratama, Reza Dian; Basyar, Edwin; Sudjarwo, Aries
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 2 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i2.1068

BACKGROUND : Atherosclerosis is associated with hypercholesterolemia and inflammation. Edamame, a high-genistein soybean variant, is believed to have protective effects against atherosclerosis. AIMS : This study aimed to determine the influence of edamame extract rich in genistein on the eosinophil-lymphocyte ratio (ELR) levels in rats induced with atherosclerosis. METHOD : This research utilized a true experimental design with a post-test only control group. Thirty male rats were divided into five groups: negative control, positive control, treatment 1 with edamame extract supplementation, treatment 2 with edamame extract rich in genistein supplementation, and treatment 3 receiving atorvastatin. After 28 days, the ELR levels were examined from rat blood. Data were analyzed using One-Way ANOVA - Bonferroni, Kruskal-Wallis – Mann-Whitney, and Pearson correlation tests. RESULT : There were no significant differences in ELR levels (p>0.05) among all treatment groups compared to the negative and positive control groups. T-tests between the negative control and positive control groups, as well as between the positive control and the three treatment groups successively, showed non-significant results (p: 0.376; 0.856; 0.169; 0.066). CONCLUSION : The administration of edamame extract rich in genistein did not significantly reduce inflammation levels in blood vessels compared to edamame extract alone, as indicated by non-significant results in the ELR difference analysis.

Pengaruh Relaksasi Benson terhadap Kualitas Tidur Mahasiswa Fakultas Kedokteran Universitas Diponegoro Roselina, Jessica; Kesoema, Tanti Ajoe; Pasmanasari, Elta Diah; Basyar, Edwin
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 39 No 3 (2022): Vol 39 No 3 (2022)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v39i3.409

Introduction: Sleep is the basic need that should be fulfilled to help the body to work optimally. Sleep disorders are quite prevalent among medical students. Sleep deprived medical students experience decreased cognitive function, mood, alertness, and fatigue. Benson relaxation is a non-pharmacological therapy that can improve sleep quality in elderly. Limited study was published on the effect of Benson relaxation on young adultsÃ¢â‚¬â„¢ sleep quality. Aim: To analyze the effect of Benson relaxation on sleep quality in students of Faculty of Medicine Diponegoro University. Methods: A non-invasive quasi experimental study with one group pre and post-test design was conducted. Which involved 29 medical students from class of 2018-2021. Purposive sampling technique was performed. Benson relaxation was done for 14 consecutive days, 15 minutes every day. The subjectÃ¢â‚¬â„¢s sleep quality was assessed by the PSQI questionnaire before and after Benson relaxation treatment. Data was analyzed using IBM SPSS Statistics 22.0 and the test used was paired T-test. Results: The pre-test score mean was 9,38 Ã‚Â± 1,821 meanwhile the post-test score mean was 4,31 Ã‚Â± 2,106. There was statistically significant change in sleep quality before and after Benson relaxation (p = 0,004). Discussion: Benson relaxation increased sleep quality in students of Faculty of Medicine Diponegoro University. Keywords: Sleep quality, medical students, Benson relaxation

Laparoscopic Cholecystectomy is Associated with Superior Clinical Outcomes in Pediatric Cholelithiasis: A 6-Year Comprehensive Surgical Outcome Analysis from Semarang, Indonesia Natasha Hartanto; Edwin Basyar; Rudiyuwono Raharjo
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 12 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i12.1469

Background: The incidence of pediatric cholelithiasis is increasing globally, driven primarily by the childhood obesity epidemic. In a nation of over 270 million people like Indonesia, with rising obesity rates, understanding the optimal surgical management is a national health priority. This study provides the first detailed, comparative surgical outcome analysis for pediatric cholecystectomy from a major Indonesian referral center. Methods: A retrospective cohort study of all pediatric patients (≤18 years) undergoing cholecystectomy from January 2019 to December 2024 was conducted. Data on preoperative demographics, clinical presentation, intraoperative variables (operative time, blood loss, conversion rate), and postoperative outcomes (length of stay, 30-day complications graded by Clavien-Dindo) were extracted. Laparoscopic (LC) and open cholecystectomy (OC) groups were compared using Mann-Whitney U and Fisher’s exact tests. Results: The cohort of 30 patients (70% female, mean age 12.0 years) had a 60% prevalence of overweight or obesity. Laparoscopy was the initial approach in 25 cases (83.3%), with one conversion to open surgery (4%). Compared to the OC group (n=6), the definitive LC group (n=24) demonstrated significantly superior outcomes: median operative time was shorter (72 vs. 115 minutes, p=0.004), median estimated blood loss was lower (15 vs. 80 mL, p<0.001), and median postoperative length of stay was significantly reduced (3 vs. 5 days, p=0.002). The postoperative complication rate was lower in the LC group (8.3% vs. 33.3%, p=0.14), with all complications being minor (Clavien-Dindo Grade I-II). Conclusion: Laparoscopic cholecystectomy is a safe, effective, and efficient procedure that provides superior clinical outcomes compared to the open approach in the Indonesian pediatric population. These findings provide robust local evidence to establish LC as the unequivocal standard of care and justify investment in minimally invasive surgical training and infrastructure to meet the rising burden of this disease.

Laparoscopic Cholecystectomy is Associated with Superior Clinical Outcomes in Pediatric Cholelithiasis: A 6-Year Comprehensive Surgical Outcome Analysis from Semarang, Indonesia Natasha Hartanto; Edwin Basyar; Rudiyuwono Raharjo
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 12 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i12.1469

Background: The incidence of pediatric cholelithiasis is increasing globally, driven primarily by the childhood obesity epidemic. In a nation of over 270 million people like Indonesia, with rising obesity rates, understanding the optimal surgical management is a national health priority. This study provides the first detailed, comparative surgical outcome analysis for pediatric cholecystectomy from a major Indonesian referral center. Methods: A retrospective cohort study of all pediatric patients (≤18 years) undergoing cholecystectomy from January 2019 to December 2024 was conducted. Data on preoperative demographics, clinical presentation, intraoperative variables (operative time, blood loss, conversion rate), and postoperative outcomes (length of stay, 30-day complications graded by Clavien-Dindo) were extracted. Laparoscopic (LC) and open cholecystectomy (OC) groups were compared using Mann-Whitney U and Fisher’s exact tests. Results: The cohort of 30 patients (70% female, mean age 12.0 years) had a 60% prevalence of overweight or obesity. Laparoscopy was the initial approach in 25 cases (83.3%), with one conversion to open surgery (4%). Compared to the OC group (n=6), the definitive LC group (n=24) demonstrated significantly superior outcomes: median operative time was shorter (72 vs. 115 minutes, p=0.004), median estimated blood loss was lower (15 vs. 80 mL, p<0.001), and median postoperative length of stay was significantly reduced (3 vs. 5 days, p=0.002). The postoperative complication rate was lower in the LC group (8.3% vs. 33.3%, p=0.14), with all complications being minor (Clavien-Dindo Grade I-II). Conclusion: Laparoscopic cholecystectomy is a safe, effective, and efficient procedure that provides superior clinical outcomes compared to the open approach in the Indonesian pediatric population. These findings provide robust local evidence to establish LC as the unequivocal standard of care and justify investment in minimally invasive surgical training and infrastructure to meet the rising burden of this disease.

The Clinical and Pathological Landscape of Pediatric Appendicitis in Central Java, Indonesia: A Retrospective Cohort Study Highlighting a High Burden of Delayed Diagnosis Dimas Susilo Waridiarto; Edwin Basyar; Rudiyuwono Raharjo
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 12 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i12.1470

Background: The timely diagnosis of pediatric appendicitis is a global challenge, particularly in low- and middle-income countries where health system barriers can lead to significant delays and increased morbidity. This study aimed to characterize the clinical and pathological presentation patterns of pediatric appendicitis at a major Indonesian referral center to identify evidence of diagnostic delay and to analyze associated surgical management trends. Methods: A retrospective cohort study was conducted at Dr. Kariadi General Hospital on all pediatric patients (n=52) who underwent appendectomy between January 2022 and December 2024. Data on demographics, definitive histopathological diagnoses, and surgical approaches were collected and analyzed. The manuscript was prepared in accordance with the STROBE guidelines for observational studies. Results: The cohort was predominantly male (63.4%), with a peak incidence in the 6–10 year age group (42.3%). The most striking finding was the histopathological diagnosis: a remarkable 48.0% of patients were diagnosed with chronic appendicitis with acute exacerbation, a strong indicator of delayed presentation. Minimally invasive surgery was performed in 48.0% of cases. While a significant association was observed between laparoscopic surgery and a shorter postoperative length of stay (p < 0.001), this finding was subject to significant confounding by indication. Conclusion: The exceptionally high prevalence of chronic exacerbated appendicitis is the principal finding of this study, serving as a powerful public health signal for systemic delays in the pediatric acute care pathway in this region. While minimally invasive surgery is associated with faster recovery, the more pressing priority is addressing the upstream factors—including public awareness and primary care referral systems—that lead to late surgical presentation and increased cumulative morbidity.

The Clinical and Pathological Landscape of Pediatric Appendicitis in Central Java, Indonesia: A Retrospective Cohort Study Highlighting a High Burden of Delayed Diagnosis Dimas Susilo Waridiarto; Edwin Basyar; Rudiyuwono Raharjo
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 12 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i12.1470

Background: The timely diagnosis of pediatric appendicitis is a global challenge, particularly in low- and middle-income countries where health system barriers can lead to significant delays and increased morbidity. This study aimed to characterize the clinical and pathological presentation patterns of pediatric appendicitis at a major Indonesian referral center to identify evidence of diagnostic delay and to analyze associated surgical management trends. Methods: A retrospective cohort study was conducted at Dr. Kariadi General Hospital on all pediatric patients (n=52) who underwent appendectomy between January 2022 and December 2024. Data on demographics, definitive histopathological diagnoses, and surgical approaches were collected and analyzed. The manuscript was prepared in accordance with the STROBE guidelines for observational studies. Results: The cohort was predominantly male (63.4%), with a peak incidence in the 6–10 year age group (42.3%). The most striking finding was the histopathological diagnosis: a remarkable 48.0% of patients were diagnosed with chronic appendicitis with acute exacerbation, a strong indicator of delayed presentation. Minimally invasive surgery was performed in 48.0% of cases. While a significant association was observed between laparoscopic surgery and a shorter postoperative length of stay (p < 0.001), this finding was subject to significant confounding by indication. Conclusion: The exceptionally high prevalence of chronic exacerbated appendicitis is the principal finding of this study, serving as a powerful public health signal for systemic delays in the pediatric acute care pathway in this region. While minimally invasive surgery is associated with faster recovery, the more pressing priority is addressing the upstream factors—including public awareness and primary care referral systems—that lead to late surgical presentation and increased cumulative morbidity.

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