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All Journal JURNAL GIZI INDONESIA Jurnal Kedokteran Diponegoro Journal of Biomedicine and Translational Research Jurnal Keperawatan Silampari Nurse and Health: Jurnal Keperawatan Jurnal Sehat Mandiri Journal of Telenursing (JOTING) Strada Jurnal Ilmiah Kesehatan (SJIK)
Muflihatul Muniroh
Department Of Physiology And Division Of Human Genetics, Center For Biomedical Research (CEBIOR),Faculty Of Medicine, Universitas Diponegoro
Biochemistry, Genetics & Molecular Biology Dentistry Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health

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The Comparation Between Plyometrics and Aerobic Exercise on Medical Student’s Mood in Diponegoro University Karoni Karoni; Muflihatul Muniroh; Marijo Marijo; Endang Kumaidah
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 2 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i2.29379

Abstract

Background: Physical activity is important to do because a sedentary lifestyle is one of the causes of various health problems in the world. One of the importance of physical activity is to improve mental health, quality of life and well-being. Physical activity significantly has a positive impact on a person's mood. Plyometrics and aerobic exercises are popular physical activities, but comparing the effects of both in improving cognitive function, especially in the mood domain, has never been done. Objective: To analyze mood differences between the group with plyometrics exercise and the group with aerobic exercise in students of the Faculty of Medicine, Diponegoro University.Methods: This study is an experimental study with parallel 3 groups pre and post-test design. The research subjects were 45 UNDIP medical students who were selected by purposive sampling and grouped into 3 groups randomly. The untreated control group (n = 15), the plyometrics treatment group (n =15), and the aerobic treatment group (n = 15). The treatment group did physical activity for 6 weeks. Mood levels were measured before and after the intervention using the Profile Of Mood States (POMS). The better a person's mood, the lower the Total Mood Disorder (TMD) score is obtained.Results : TMD scores (pre-test to post-test) in the plyometrics (p <0.001) and aerobic (p = 0.001) groups both experienced a significant decrease. However, there was no significant difference between the TMD post-test scores in the plyometrics treatment group and the aerobic treatment group.Conclusion: Plyometrics and aerobic exercise has a similar effect on improving mood score.
Characteristics of Endometriosis Patients in RSUP Dr. Kariadi Semarang in 2018 Syarifah A Mansur; Yuli Trisetiyono; Muflihatul Muniroh; Nurul Setiyorini
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 2 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i2.30722

Abstract

Background : Endometriosis is one of the gynecological disorders that affects women at reproductive age between 20-35 years. Based on the above, endometriosis can cause pain that can interfere daily activity and infertility.Aim : To found the incidence and characteristics of patients with endometriosis who undergoing treatment and surgery in RSUP Dr. Kariadi Semarang Method: This study was a descriptive study. Data retrieved from medical records of endometriosis’s patients who undergoing treatment and surgery at RSUP Dr. Kariadi Semarang 2018. The result presented in distribution and frequency characteristics tables.Result : The incidence of endometriosis in RSUP Dr. Kariadi Semarang in 2018 were 176 cases of 8690 inpatients in the obstetric and gynecology wards. Characteristics of endometriosis patients are most at the age of 20 - 35 years, nullipara, with complaints of menstrual pain / dysmenorrhoea, location in the ovary, by managing the surgery and using GnRH agonists, and not a recurrent endometriosis patient.Conclusion : The incidence of endometriosis in RSUP Dr. Kariadi Semarang 2018 was 176 cases of 8690 patients at the Obstetrics and Gynecology (2 %). Endometrosis highest incidence was in the reproductive age (20-35 years).
Body Mass Index and Waist Circumference are Associated with Visceral Fats Measured by Bioelectrical Impedance Analysis in Adolescents Darmawati Ayu Indraswari; Hafizhil Uzhma Al Ahmadi; Devi Wahyu Arum Sari; Timothy Jordan; Buwono Puruhito; Edwin Basyar; Saekhol Bakri; Muflihatul Muniroh
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 5 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i5.32040

Abstract

Background: Overweight and obesity are two health conditions that contribute to the impaired quality of life. Two parameters of obesity also indicating body composition, body mass index (BMI) and waist circumference (WC), have been used as simple tools to assess abdominal visceral fats. The correlation between both measurements and visceral fats remains unclear.Objective: The study aims at demonstrating that body mass index and waist circumference may reflect visceral fats using bioelectrical impedance analysis in adolescents.Methods: First-year students of the Faculty of Medicine Diponegoro University participated in the study. This cross-sectional study measured BMI, WC, mid-arm circumference (MAC), and visceral fat (VF) of 130 participants. BMI, WC, MAC, and VF were assessed using Omron digital scale, measuring tape, and body impedance analysis, respectively. Spearman test was used for the bivariate analysis while multiple regression was employed to perform multivariate analysis. Significant results were determined if p value <0.05 for the bivariates.Results: The correlation between body mass index and visceral fats showed a strong value with r: 0.794 and p-value=<0.001. The correlation between mid-arm circumference and visceral fats showed r= 0.713 and p value=<0.001. Meanwhile the correlation between waist circumference and visceral fats showed r= 0.655 and p value=<0.001. BMI and WC showed the greatest correlation to VF. The comparison between genders resulted in men having stronger relationships between BMI and VF, and WC and VF.Conclusion: BMI and waist circumference are strongly related to visceral fats based on BIA in medical students. 
Effectivity Of Annona Muricata and Artemisinin Combined Therapy on Brain CXCL10 expression (Study in Swiss Mice During Severe Plasmodium Berghei ANKA Infection) Abdulhakim Sulayman; Kis - Djamiatun; Muflihatul Muniroh
Journal of Biomedicine and Translational Research Vol 5, No 2 (2019): December 2019
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v5i2.4802

Abstract

ABSTRACTBackground: Malaria, caused by Plasmodium sp infection, is a major global cause of morbidity and mortality. Most experimental cerebral malaria (ECM) studies show increase number of Th1 cells and CTLs in the brain, due to increase chemokine expression, including CXCL10, a potent chemokine involved in cerebral malaria (CM). Recent studies show that CXCL10 provokes apoptosis of human brain micro-endothelial cells and in vitro neuroglia cells.Objective: To determine whether combination of Annona muricata-leaf-extracted-by-water (AME) and artemisinin-combination-therapy (ACT) reduce brain-CXCL10-expression of Swiss-mice inoculated with P. berghei ANKA (PbA). Methods: This was an experimental-study with post-test-only-control-group-design. Twenty-four Swiss-mice (PbA-inoculated) were randomly divided into 4 groups. Control group (C) was PbA inoculated only. X1, X2 and X3 groups received AME, ACT and combination of AME and ACT treatment, respectively.  CXCL10 was stained with in immunohistochemistry, which then observed by light microscope in order to determine Allred-score. Kruskal-Wallis test was used to statistically analyze the differences among groups, then followed by a Mann- Whitney U test.Result: C and X1groups had severe-PbA-infection when the study was end on day-7-PbA-infection, while X2 and X3 groups entered recovery-stage. The AME-ACT-treatment-group had significantly lower of brain-CXCL10-expression than AME-group (p=0.008) and nearly significantly lower than control-group (p=0.058). Group that received ACT alone had no different value of brain-CXCL10-expression than control-group (p=0.502) and combination AME–ACT group (p=0.335).Conclusion: The combination of AME–ACT treatment decreases brain-CXCL10-expression of Swiss-mice during PbA-infection-recovery-stage, indicating the effectivity of AME–ACT combined therapy is better prevention of cerebral malaria than AME alone.
EXPERIENCES OF PEOPLE LIVING WITH HIV/AIDS IN SURVIVING LIFE Bagas Biyanzah Drajad Pamukhti; Meira Erawati; Muflihatul Muniroh; Nur Setiawati Dewi
Nurse and Health: Jurnal Keperawatan Vol 10 No 2 (2021): Nurse and Health: Jurnal Keperawatan July-December 2021
Publisher : Institute for Research and Community Service of Health Polytechnic of Kerta Cendekia, Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36720/nhjk.v10i2.293

Abstract

Background: Fear of contracting HIV in the community causes discrimination and stigma to people living with HIV/AIDS (PLWHA) because people still consider HIV/AIDS taboo. Many of the sufferers struggle to reveal their HIV status to others, but they get negative results such as rejection, stigmatization and even discrimination which can be a high psychological burden. Stigma and discrimination against PLWHA are the main obstacles to achieving a good quality of life. Objectives: This study is intended to explore the in-depth experiences of people living with HIV/AIDS in surviving life. Methods: This research is a phenomenological case study. The sample in this study amounted to three people who were recruited from Healthy Loving Care Foundation Semarang City. The sample was determined using a purposive sampling technique according to the inclusion criteria, that is age 20 and 50 years, diagnosed with HIV/AIDS, conscious, cooperative, not experiencing cognitive, hearing and speech disorders, willing to participate in the study by signing the informed consent. The data was collected by in-depth online interviews and then recorded in transcripts and analyzed using Amedeo Giorgi's data analysis technique. Results: This study showed that participants experience adversity due to HIV/AIDS but the participants get out of their slump by accepting their illness, taking treatment, finding a support system and becoming a positive people. The participants also in living their lives keep their illness a secret to survive so as not to experience bad stigma or discrimination. The results of this study reveal one main theme, Experiences of People living with HIV in Surviving life. Conclusion: This study found the support received by participants and the response of participants to their condition as an effort to survive their lives.
Effects of Sorghum Cookies (Sorghum Bicolor L. Moench) on Fasting Glucose, Triglyceride, High-Density Lipoprotein level, and Body Fat Percentage in Adolescent Obesity Latifah Rachmawati; Maria Mexitalia; Muflihatul Muniroh; Diana Nur Afifah; Adriyan Pramono
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 10, No 2 (2022): Juni
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.10.2.181-188

Abstract

Background: Adolescent obesity is related to the risk of metabolic syndrome. Several studies have proven the effect of dietary interventions on metabolic parameters in obese individuals. A source of complex carbohydrates that is still rarely developed in the obese diet is sorghum which contains resistant starch.Objective: The study was to reveal the effect of sorghum cookies on Fasting Glucose (FG), Triglycerides (TG), High-Density Lipoprotein (HDL), and Body Fat Percentage (BFP) in obese adolescents.Materials and Methods: This quasi-experiment with the pre-post control-group design was conducted on 20 boys and 20 girls (divided into 10-boy control group, 10-girl control group, 10-girl intervention group, and 10-girls intervention group) with the age range of 13–15 years who attended Junior High School 14 Semarang chosen by consecutive sampling. Weight, Height, and BFP were measured directly by BIA. Metabolic parameters (FG, TG, and HDL levels) were taken through venous and 10-hour fasting. Energy intake and physical activity were taken by interview using the food recall questionnaire for 6 days randomly and IPAQ. The intervention of sorghum cookies was given in 90 grams/day with 473 kcal/day for 28 days. The analysis of the effect of the intervention was conducted by a paired t-test and independent t-test.Results: At 28-days sorghum cookies intervention resulted in lower levels of FG, TG, and BFP in the intervention boy group (p < 0.05) and BFP in the girl group (p < 0.05). The intervention of sorghum cookies showed no effect on HDL levels in boys, and it did not affect FG, TG, or HDL levels of the girl subjects (p > 0.05). Conclusion: Obese adolescents who had been receiving intervention of 90 grams of sorghum cookies for 28 days appeared to have lower levels of fasting glucose, triglycerides, and body fat percentage.
EFFECT OF HIGH INTENSITY CIRCUIT TRAINING IN PEAK EXPIRATORY FLOW RATE VALUE AMONG MALE YOUNG ADULTS Yohana Revi Imanita; Endang Ambarwati; Muflihatul Muniroh; Yosef Purwoko
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 4 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i3.33114

Abstract

Background: Lung function has mutual correlation with exercise. Abnormal lung function can affect physical ability to exercise. Otherwise, exercise can increase lung function. Peak expiratory flow rate (PEFR) is a parameter to observe the lung function. High Intensity Circuit Training (HICT) is a combination of aerobic and endurance exercise which has total duration only 7-minutes long. High Intensity Circuit Training can be a good choice for young adults because it does not need much time, easy to be practiced, and beneficial for physical health as well. Objective: To analyze a significant increase in PEFR value after High Intensity Circuit Training for 8 weeks. Methods: This study was a quasi-experimental study with pre-test and post-test comparison group method. Samples were taken purposively from medical student of Diponegoro University (n=56, age=18-21 years old), who were divided into two groups, the control and training group. Peak flow meter was used to measure PEFR value before and after intervention. The data were analysed using Paired T test and Independent T test. Results: A significant increase of PEFR value was found after High Intensity Circuit Training for 8 weeks (p=0.000). The mean difference between pre-test and post-test PEFR value was found increased significantly (p=0.001), that training group had higher score as compared to control group. Conclusion: Regular High Intensity Circuit Training can improve lung function particularly PEFR value in male young adults.
THE EFFECTIVENESS OF KAFFIR LIME PEEL EXTRACT (Citrus hystrix) ON PLASMA MALONDIALDEHYDE LEVEL IN DEMENTIA MICE Muhammad Ilham; Endang Mahati; Muflihatul Muniroh; Yora Nindita
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 5 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i5.35304

Abstract

ABSTRACTBackground: Antioxidant is a substance that can catch and neutralize free radicals so that the process of oxidative stress can be stopped and cell damage can be avoided. Kaffir lime peel contains antioxidant compounds that have the potential to be the neuroprotective agent and can protect neurons from free radical-induced damage.Objective: To evaluate the effect of kaffir lime peel extract (Citrus hystrix) on the plasma malondialdehyde (MDA) level of mice induced by Scopolamine (SCM).Method: This research was a true experimental study with a post-test-only controlled group design. Thirty mice were randomly divided into 5 groups consisting of a healthy control (K+), Negative Control (K-), extract 5 mg/20gBW group (P1), 10 mg/20gBW group (P2), 20 mg/20gBW group (P3). SCM was injected intraperitoneally on days 1-7 and kaffir lime peel extract was given orally on days 2-7, the MDA levels testing of mice using TBARS method on day 8. Data analysis used One-Way ANOVA test and continued with Post Hoc LSD test.Results: The mean MDA levels of K+, K-, P1, P2, P3 were 4,212; 4,644; 3,481; 4,555; 4,733 nmol/mL, respectively. MDA levels of P1 were lower than K-, even though there were no statistically significant differences.Conclusion: There was no effect of administration kaffir lime peel extract (Citrus hystrix) on MDA levels in mice with scopolamine-induced dementia.Keywords: Citrus hystrix, malondialdehyde, dementia, mice
Relaksasi Otot Progresif pada Penatalaksanaan Nyeri Pasien Pasca Operasi Dwi Sudaryanti; Fitria Handayani; Muflihatul Muniroh; Weni Sulastri
Journal of Telenursing (JOTING) Vol 5 No 1 (2023): Journal of Telenursing (JOTING)
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/joting.v5i1.5833

Abstract

This study aims to determine the effectiveness of progressive muscle relaxation interventions in reducing pain levels in postoperative patients. The research method used is scoping review. The results showed that the intervention of progressive muscle relaxation reduced postoperative patients' pain levels. In conclusion, advanced muscle relaxation interventions as non-pharmacological therapy effectively reduce postoperative pain levels. Keywords: Pain, Postoperative, Progressive Relaxation
Stabilitas Vitamin D3 pada Dadih (Susu Kerbau Fermentasi) Sari Bema Ramdika; Diana Nur Afifah; Anang Mohamad Legowo; Muflihatul Muniroh; Yora Nindita; Endang Mahati
Jurnal Sehat Mandiri Vol 18 No 1 (2023): Jurnal Sehat Mandiri, Volume 18, No.1 Juni 2023
Publisher : Poltekkes Kemenkes Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33761/jsm.v18i1.914

Abstract

Vitamin D deficiency and inadequacy is a worldwide problem that can cause serious health problems. Vitamin D reduce the risk of osteoporosis, cancer, diabetes mellitus, and cardiovascular disease. Vitamin D is obtained from four sources such as sun exposure, food, supplements and fortification food. The research was conducted in October 2019. The purpose of this study was to see the stability of vitamin D3 in dadih during storage. The High Performance Liquid Chromatogaphy (HPLC) method was used to calculate vitamin D3 levels in fortified dadih. Quantification of vitamin D3 was done on day 0, day 3, day 9, day 16, day 23 and day 30. Statistical analysis showed that there was no significant difference in the level of vitamin D3 in dadih for 30 days of storage although there was a decrease in the level of vitamin D3 in dadih on the fourth week but it was not significantly (p> 0.05). In conclusion, Vitamin D3 in the dadih was stable for 30 days of storage although there was a decrease in vitamin D3 levels on the 16th and 30th days of storage due to the undetectable vitamin D3 in some samples. The addition of vitamin D3 to dadih is suggested using encapsulation techniques to increase solubility, longer shelf life, prevention of chemical degradation, better dispersibility, higher bioavailability and effectiveness.
Co-Authors - Anggorowati Abdulhakim Sulayman Adriyan Pramono Anang M Legowo Anggrayeni Purba Aninditya Artina Setiaputri Bambang Cahyono Buwono Puruhito Darmawati Ayu Indraswari Defita Faridlotus Shalihah Devi Wahyu Arum Sari Diana Nur Afifah, Diana Nur Dwi Sudaryanti Dwi Susilawati Edwin Basyar Endang Ambarwati Endang Kumaidah Endang Mahati Endang Mahati Fronthea Swastawati Hafizhil Uzhma Al Ahmadi Handayani, Fitria Karoni Karoni Kis - Djamiatun Latifah Rachmawati Maria Mexitalia Marijo Marijo Meira Erawati Muhammad Ilham Nur Setiawati Dewi Nurul Setiyorini Pamukhti, Bagas Biyanzah Drajad Pryati Rihi Saekhol Bakri, Saekhol Sari Bema Ramdika Slamet Suharto Syarifah A Mansur Timothy Jordan Untung Sujianto Weni Sulastri Yohana Revi Imanita Yora Nindita Yora Nindita Yosef Purwoko Yuli Trisetiyono