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All Journal Global Medical and Health Communication Jurnal ABDINUS : Jurnal Pengabdian Nusantara Jurnal Integrasi Kesehatan dan Sains Jurnal Riset Kedokteran Bandung Conference Series : Medical Science
Wida Purbaningsih
Departemen Ilmu Histologi Fakultas Kedokteran Universitas Islam Bandung
Humanities Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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Granuloma pada Limfadenitis TB: Kajian Pustaka Aurora Rahma Koesdinar; Wida Purbaningsih; Ismet Muchtar Nur
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.1831

Abstract

Abstract. Tuberculosis (TB) is an infectious infectious disease caused by Mycobacterium tuberculosis (M.tb) and is the 10th leading cause of death that ranks 4th in the world. Incidence of extrapulmonary TB events generally occurs in several organs, namely TB lymphadenitis, TB pleurisy, TB peritonitis, Miliary TB, TB meningitis, bone and joint TB. Tuberculous lymphadenitis represents about 30%–40% of cases of extrapulmonary tuberculosis. Histopathological picture TB lymphadenitis will usually be found granulomas, necrosis caseouse, epitheloid cells and Langhan's cells. Granulomas serve to isolate antigens from the host which will provide the body with protection from the introduction of antigens that are important in mycobacterial infections. Abstrak. Tuberkulosis (TB) adalah penyakit infeksi menular yang disebabkan oleh Mycobacterium Tuberculosis (M.tb) dan merupakan 10 penyebab kematian utama yang berada di urutan ke-4 di dunia. Insidensi kejadian TB ekstraparu pada umumnya terjadi pada beberapa organ yaitu Limfadenitis TB, Pleuritis TB, Peritonis TB, Miliary TB, Meningitis TB, TB tulang dan sendi. Limfadenitis TB mewakili sekitar 30%–40% dari kasus tuberkulosis ekstraparu. Gambaran histopatolgi Limfadenitis TB biasanya akan ditemukan granuloma, necrosis caseouse, epitheloid cell dan langhan’s cell. Granuloma berfungsi untuk mengisolasi antigen dari inang yang akan memberi tubuh perlindungan dari pengenalan antigen yang penting pada infeksi mikrobakteri.
Pengontrolan Glukosa Darah dapat Mencegah terjadinya Tuberkulosis: Kajian Pustaka Annisa Humairra; Wida Purbaningsih; Winni Maharani
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.1977

Abstract

Abstract. Tuberculosis (TBC) is an infectious disease caused by Mycobacterium tuberculosis (M.tb), the third leading cause of death in the world and one of the ten leading causes of death. There are several factors that can affect the course of type 2 DM that they are more likely susceptible to TBC, namely, changes in metabolism and blood glucose control through medication. Type 2 diabetes mellitus is a chronic metabolic disease caused by insulin resistance and decreased insulin secretion which causes impaired glucose utilization, hyperinsulinemia, dyslipidaemia, and pancreatic beta cell dysfunction. Lifestyle changes are needed, including diet and exercise, and pharmacological treatment consisting of oral drugs and injections is needed to achieve good blood glucose levels that can reduce the risk of macrovascular and microvascular complications, and also increase the immune response that can minimize the risk of infection. Abstrak. Tuberkulosis (TBC) adalah suatu penyakit menular yang disebabkan oleh Mycobacterium tuberculosis (M.tb), penyebab kematian ketiga di dunia dan salah satu dari sepuluh penyebab utama kematian. Ada beberapa faktor yang dapat mempengaruhi perjalanan penyakit DM tipe 2 sehingga lebih rentan terhadap TBC yaitu, adanya perubahan metabolisme dan pengontrolan glukosa darah melalui pengobatan. DM tipe 2 merupakan penyakit metabolik kronis yang disebabkan oleh resistensi insulin dan penurunan sekresi insulin yang menyebabkan gangguan penggunaan glukosa, hiperinsulinemia, dislipidemia, serta disfungsi sel beta pankreas. Diperlukan adanya perubahan gaya hidup termasuk diet dan berolahraga, dan pengobatan farmakologis yang terdiri dari obat oral dan suntikan diperlukan untuk mencapai kadar glukosa darah yang baik yang dapat menurunkan risiko komplikasi makrovaskular dan mikrovaskular, dan juga meningkatkan respon imun yang dapat meminimalkan risiko terjadinya infeksi.
Scoping Review: Pengaruh Terapi Herbal pada Pasien Tuberkulosis sebagai Antioksidan dan Imunomodulator Diemas Abdurahman Hernawan; Wida Purbaningsih Purbaningsih; Tryando Batara
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.2098

Abstract

Abstract. Tuberculosis (TB) is still a health problem in Indonesia and around the world. Traditional medicine, including herbal medicine, has been recommended by WHO for the maintenance of public health, prevention, and treatment of diseases, especially chronic diseases, one of which is TB. Several studies have stated that the role of antioxidants and immunomodulators in herbs is important for TB patients as a complementary therapy. This study aims to determine the effect of giving herbs to TB patients as antioxidants and immunomodulators. The research was conducted using the Scoping Review method by searching for articles from the Pubmed, Science Direct, ProQuest, and Springerlink databases. obtained 892 articles, then the inclusion criteria were carried out so that the number of articles obtained was 3 articles. The results stated in the first article stated that Withania somnifera was able to increase CD4 and CD8, the second article showed gingerol could reduce TNF-alpha and MDA levels, and the third article showed green tea could reduce NO production levels. The conclusion from the three studies is that herbal therapy is able to increase CD4 and CD8, reduce TNF-alpha levels, and reduce NO production levels. Abstrak. Tuberkulosis (TB) masih menjadi masalah Kesehatan di Indonesia dan di dunia. Pengobatan tradisional termasuk obat herbal telah direkomendasikan oleh WHO untuk pemeliharaan Kesehatan masyarakat, pencegaha, dan pengobatan penyakit terutama penyakit kronis salah satu nya adalah TB. Beberapa penelitian menyebutkan peranan antioksidan dan imunomodulator pada herbal penting bagi pasien TB sebagai terapi komplementer. penelitian ini bertujuan untuk mengetahui pengaruh pemberian herbal pada pasien TB sebagai antioksidan dan imunomodulator. Penelitian dilakukan dengan metode Scoping Review dengan pencarian artikel yang berasal dari database Pubmed, Science Direct, Pro Quest, dan Springerlink. Didapatkan 892 artikel, kemudian dilakukan kriteria inklusi sehingga jumlah artikel yang didapat adalah 3 artikel. Hasil pada artikel pertama menyebutkan bahwa Withania somnifera mampu meningkatkan CD4 dan CD8, pada artikel kedua menunjukan gingerol dapat menurunkan Level TNF alpha dan MDA, dan pada artikel ketiga menunjukan Green tea dapat menurunkan level produksi NO. Kesimpuulan dari ketiga penelitian tersebut adalah terapi herbal mampu meningkatkan CD4 dan CD8, mampu menurunkan level TNF alpha, dan mampu menurunkan level produksi NO.
Kejadian Hiperglikemia Baru Akibat Infeksi Covid-19 Lukman Hakim Muttaqien; Yani Triyani; Wida Purbaningsih
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.5564

Abstract

Abstract. Coronavirus disease (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. The SARS-CoV-2 virus has a spike-like protein (S) structure, which will bind to the angiotensin converting enzyme 2 (ACE2) receptor. The number of tissues that express ACE2 receptors causes varied symptoms, ranging from mild symptoms such as coughing, to severe symptoms such as digestive disorders, heart failure, hypertension, and other systemic disorders such as hyperglycemia. So that there are many cases of increased blood sugar levels in COVID-19 patients which cause hyperglycemia. This study aims to determine the relationship between the incidence of new hyperglycemia and COVID-19. This study was conducted by taking medical record data at Al-Islam Hospital in the January-September 2021 period to obtain data on COVID-19 hospitalized patients and data on current blood sugar. This study used an analytical observational method with a case control design and the sampling technique was carried out using the total sampling method and analysis using the chi-square test. The medical record samples studied were 171 medical records at Al-Islam Bandung Hospital. The results showed that most of the subjects experienced hyperglycemia as many as 44 people (51.8%), and there was a significant relationship between COVID-19 infection and the incidence of hyperglycemia (P=0.038). COVID-19 infection is one of the causes of hyperglycemia. Abstrak. Penyakit Coronavirus (COVID-19) adalah penyakit infeksius yang disebabkan oleh virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Virus SARS-CoV-2 memiliki struktur protein seperti spike protein (S), yang akan berikatan dengan reseptor angiotensin converting enzyme 2 (ACE2). Banyaknya jaringan yang mengekspresikan reseptor ACE2 menimbulkan gejala yang bervariasi, berawal dari gejala ringan seperti batuk, hingga gejala berat seperti gangguan pencernaan, gagal jantung, hipertensi, dan gangguan sistemik lain seperti hiperglikemia. Sehingga banyak kasus kenaikan kadar gula darah pada pasien COVID-19 yang menyebabkan hiperglikemia. Penelitian ini bertujuan untuk mengetahui hubungan antara kejadian hiperglikemia baru dengan COVID-19. Penelitian ini dilakukan dengan mengambil data rekam medis di RS Al-Islam pada periode Januari–September 2021 untuk mendapatkan data pasien rawat inap COVID-19 dan data gula darah sewaktu. Penelitian ini menggunakan metode observasional analitik dengan rancangan kasus control dan Teknik pengambilan sample dilakukan dengan metode total sampling serta analisis menggunakan uji chi-square. Sampel rekam medis yang diteliti sebanyak 171 rekam medis di RS Al-Islam Bandung. Hasil penelitian didapatkan Sebagian besar subjek mengalami hiperglikemia sebanyak 44 orang (51,8%), dan terdapat hubungan yang signifikan antara infeksi COVID-19 dengan kejadian hiperglikemia (P=0,038). Infeksi COVID-19 menjadi salah satu penyebab hiperglikemia.
Hubungan Terapi rtPA Dengan Perbaikan Outcome Motorik Pasien Stroke Iskemik Pada Masa Pandemi COVID-19 di Rumah Sakit Al-Islam Bandung Adli Giardin; Alya Tursina; Wida Purbaningsih
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.5825

Abstract

Abstract. COVID-19 pandemic caused a change in regulations that required all patients entering the emergency department (IGD) to be screened for COVID-19. This causes a prolongation of the door to needle time in the rtPA management of ischemic stroke patients. This prolongation of treatment time can affect motor outcomes in patients. The purpose of this study was to analyze differences in door to needle in the management of rtPA ischemic stroke patients in the period before and during the COVID-19 pandemic on motor outcomes at Al-Islam Hospital Bandung. This study was an analytic observational study with a retrospective cohort design. Subjects in this study amounted to 41 patient taken by total sampling. Door to needle secondary data and patient motor outcomes were taken directly from the patient's medical record at Al-Islam Hospital Bandung. Processing of research data was carried out in a computerized manner including univariate and bivariate analysis using the Mann Whitney U test. The study showed that before the pandemic the motor outcome in patients had improved (76%) while during the pandemic the motor outcome in patients had improved (75%) and a value of p = 0.101 was obtained. It was concluded that there was no difference in door to needle administration of rtPA on motor outcomes before and during the COVID-19 pandemic. This is influenced by regulations, rtPA management criteria, and health risk factor. Keywords: Door to Needle, Outcome motoric, rtPA, Stroke iskemic Abstrak. Pandemi COVID-19 menyebabkan perubahan regulasi yang mewajibkan semua pasien yang masuk instalasi gawat darurat (IGD) wajib melakukan skrining COVID-19. Hal ini menyebabkan terjadinya pemanjangan waktu door to needle pada penatalaksanaan rtPA pasien stroke iskemik. Pemanjangan waktu penatalaksanaan ini dapat mempengaruhi outcome motorik pada pasien. Tujuan penelitian ini yaitu untuk menganalisis pengaruh pandemi COVID-19 terhadap door to needle dan outcome motorik pada penatalaksanaan rtPA pasien stroke iskemik di Rumah Sakit Al-Islam Bandung. Penelitian ini adalah observasional analitik dengan desain penelitian kohort retrospektif. Subjek pada penelitian ini berjumlah 41 pasien yang diambil dengan total sampling. Data sekunder door to needle dan outcome motorik pasien diambil langsung melalui rekam medis pasien di RS Al-Islam Bandung. Pengolahan data penilitian ini menggunakan analisis univariat dan bivariat dengan menggunakan uji Mann Whitney. Penelitian menunjukan pada sebelum pandemi hasil outcome motorik pada pasien mengalami perbaikan (76%) sedangkan pada saat pandemi hasil outcome motorik pada pasien mengalami perbaikan (75%) dan didapatkan nilai p=0,101. Disimpulkan bahwa tidak terdapat perbedaan door to needle pemberian rtPA terhadap outcome motorik sebelum dan selama pandemi COVID-19. Hal ini dipengaruhi oleh regulasi, kriteria penatalaksanaan rtPA, dan faktor risiko kesehatan. Kata Kunci: Door to needle, outcome motorik, rtPA, Stroke iskemik
Karakteristik Demografi dan Klinikopatologi Pasien Kanker Paru di Rumah Sakit Umum Daerah Al−Ihsan Aida Fitriyane Hamdani Aida; Wida Purbaningsih; Widhy Yudistira Nalapraya
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.6154

Abstract

Abstract. Lung cancer is a disease with the highest incidence in the world and is considered non-communicable. Based on the 2020 Global Burden of Cancer (GLOBOCAN), it is estimated that there are 2.2 million people in the world suffering from lung cancer with a percentage of 11.4% of all cancer-related incidents, with a mortality rate of 1.8 million, or 18% of the total cancer-related deaths. In 2020, the incidence of finding new cases of lung cancer in Indonesia reached 34,783 cases. Meanwhile, the death rate reached 30,843 people, which is in first place. The province in Indonesia that has a high prevalence of lung cancer is the province of West Java. Al-Ihsan Hospital is one of them as a Cancer center or hospital which is a referral center for West Java residents. This study aims to look at the demographic and clinicopathological characteristics of people with lung cancer at Al-Ihsan Hospital, West Java in 2020 and 2021. This study used a retrospective descriptive observational method with a sample size measured using total sampling. From this study it can be concluded that of the 82 patients who met the inclusion criteria, there were 49 patients in 2020 and 33 patients in 2021 with the highest age group, namely 55−64 years and dominated by men. It can also be concluded that the characteristics of lung cancer patients based on clinical symptoms are the most commonly found, namely patients with shortness of breath and chest pain. Based on the type of histopathology, the most common type is non-small cell lung carcinoma. Meanwhile, based on staging with an average staging, namely staging IV. Keywords: Age, clinical symptoms, gender, histopatological type, lung cancer, staging. Abstrak. Kanker paru merupakan penyakit dengan insiden paling tinggi di dunia dan dianggap tidak menular. Berdasarkan Global Burden of Cancer (GLOBOCAN) tahun 2020, diperkirakan terdapat 2,2 juta penduduk di dunia menderita kanker paru dengan persentase 11,4% dari semua insiden yang berhubungan dengan kanker, dengan tingkat kematian 1,8 juta, atau 18% dari jumlah kematian yang berhubungan dengan kanker. Tahun 2020, kejadian penemuan kasus baru kanker paru di Indonesia mencapai 34.783 kasus. Sementara itu, angka kematiannya mencapai 30.843 jiwa yang berada pada urutan pertama. Provinsi di Indonesia yang mempunyai prevalensi dengan jumlah tinggi pada pengidap kanker paru adalah provinsi Jawa Barat. RSUD Al-Ihsan salahsatunya sebagai Cancer centre atau rumah sakit yang menjadi pusat rujukan warga Jawa Barat. Penelitian ini bertujuan untuk melihat karakteristik demografi dan klinikopatologi pengidap kanker paru di RSUD Al-Ihsan Jawa Barat pada tahun 2020 dan 2021. Penelitian ini menggunakan metode observasional deskriptif retrospektif dengan besar sampel yang diukur penggunakan total sampling. Dari penelitian ini dapat disimpulkan bahwa dari 82 pasien yang memenuhi kriteria inklusi terdiri dari 49 pasien tahun 2020 dan 33 pasien tahun 2021 dengan kelompok usia tertinggi yaitu 55−64 tahun dan didominasi oleh laki-laki. Dapat disimpulkan pula bahwa karakterisitik pasien kanker paru berdasarkan gejala klinis yang paling banyak ditemukan yaitu pasien dengan sesak nafas dan nyeri dada. Berdasarkan jenis histopatologi, jenis yang paling banyak adalah non small cell lung carcinoma. Sedangkan, berdasarkan staging dengan rata-rata staging yaitu staging IV. Kata Kunci: Gejala Klinis, Jenis Kelamin, jenis histopatologi, kanker paru, staging, usia
Gambaran Karakteristik Pasien Hipertensi di Puskesmas Kalipucang Zulfi Noor Fadia; Titik Respati; Wida Purbaningsih
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.6649

Abstract

Abstract. Hypertension is a complex disease because it can damage many organ systems. The prevalence of hypertension in Indonesia is still increasing until now. The increase in cases is due to hypertension being a multifactorial disease. The risk factors for hypertension are classified as modifiable and non-modifiable. Therefore, researchers are interested in studying the description of the characteristics of hypertensive patients at the Kalipucang Health Center. This study used an analytic observational method with a cross-sectional design. The sampling technique is consecutive sampling. Patient data was taken from the Kalipucang Health Center medical records. Obtained data on hypertension patients as many as 129 patients. The results showed that the majority of hypertension patients at the Kalipucang Health Center were aged ≥60 (68.2%), women (93.8%), obesity 1 (35.7%), and stage 1 hypertension (46.5%). It was concluded that the characteristics of hypertension patients at the Kalipucang Health Center were ≥60 years old, female, obese 1, and had stage 1 hypertension. Abstrak. Hipertensi adalah penyakit yang bersifat kompleks karena dapat merusak banyak sistem organ. Sampai saat ini prevalensi kejadian hipertensi di Indonesia masih terus meningkat. Peningkatan kasus disebabkan karena hipertensi merupakan penyakit yang bersifat multifaktorial. Faktor risiko hipertensi dibedakan menjadi dapat dimodifikasi dan tidak dapat dimodifikasi. Oleh karena itu peneliti tertarik untuk meneliti tentang gambaran karakteristik pasien hipertensi di Puskesmas Kalipucang. Penelitian ini menggunakan metode observasional analitik dengan desain cross-sectional. Teknik pengambilan sampel yaitu dengan consecutive sampling. Data pasien diambil dari data rekam medis di Puskesmas Kalipucang sehingga diperoleh data pasien hipertensi sebanyak 129 pasien. Hasil menunjukan bahwa mayoritas pasien hipertensi di Puskesmas Kalipucang berusia ≥60 (68,2%), Wanita (93,8%), Obesitas 1 (35,7%), dan hipertensi stage 1 (46,5%). Disimpulkan bahwa gambaran karakteristik pasien hipertensi di Puskesmas Kalipucang adalah berusia ≥60, wanita, obesitas 1, dan memiliki hipertensi stage 1.
Karakteristik Demografi dan Klinikopatologi Pasien Kanker Paru di RSUD Al−Ihsan Aida Fitriyane Hamdani; Wida Purbaningsih; Widhy Yudistira Nalapraya
Jurnal Riset Kedokteran Volume 3, No.2, Desember 2023, Jurnal Riset Kedokteran (JRK)
Publisher : UPT Publikasi Ilmiah Unisba

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jrk.v3i2.2959

Abstract

Abstract. Based on the 2020 Global Burden of Cancer (GLOBOCAN), it is estimated that there are 2.2 million people in the world suffering from lung cancer with a percentage of 11.4% of all cancer-related incidents, with a mortality rate of 1.8 million, or 18% of the total cancer-related deaths. In 2020, the incidence of finding new cases of lung cancer in Indonesia reached 34,783 cases. Meanwhile, the death rate reached 30,843 people, which is in first place. Al-Ihsan Hospital is one of them as a Cancer center or hospital which is a referral center for West Java residents. This study aims to look at the demographic and clinicopathological characteristics of people with lung cancer at Al-Ihsan Hospital, West Java in 2020 and 2021. This study used a retrospective descriptive observational method with a sample size measured using total sampling. From this study it can be concluded that of the 82 patients who met the inclusion criteria, there were 49 patients in 2020 and 33 patients in 2021 with the highest age group, namely 55−64 years and dominated by men. It can also be concluded that the characteristics of lung cancer patients based on clinical symptoms are the most commonly found, namely patients with shortness of breath and chest pain. Based on the type of histopathology, the most common type is non-small cell lung carcinoma. Meanwhile, based on staging with an average staging, namely staging IV. Abstrak.  Berdasarkan Global Burden of Cancer (GLOBOCAN) tahun 2020, diperkirakan terdapat 2,2 juta penduduk di dunia menderita kanker paru dengan persentase 11,4% dari semua insiden yang berhubungan dengan kanker, dengan tingkat kematian 1,8 juta, atau 18% dari jumlah kematian yang berhubungan dengan kanker. Tahun 2020, kejadian penemuan kasus baru kanker paru di Indonesia mencapai 34.783 kasus. Sementara itu, angka kematiannya mencapai 30.843 jiwa yang berada pada urutan pertama. RSUD Al-Ihsan salahsatunya sebagai Cancer centre atau rumah sakit yang menjadi pusat rujukan warga Jawa Barat. Penelitian ini bertujuan untuk melihat karakteristik demografi dan klinikopatologi pengidap kanker paru di RSUD Al-Ihsan Jawa Barat pada tahun 2020 dan 2021. Penelitian ini menggunakan metode observasional deskriptif retrospektif dengan besar sampel yang diukur penggunakan total sampling. Dari penelitian ini dapat disimpulkan bahwa dari 82 pasien yang memenuhi kriteria inklusi terdiri dari 49 pasien tahun 2020 dan 33 pasien tahun 2021 dengan kelompok usia tertinggi yaitu 55−64 tahun dan didominasi oleh laki-laki.  Dapat disimpulkan pula bahwa karakterisitik pasien kanker paru berdasarkan gejala klinis yang paling banyak ditemukan yaitu pasien dengan sesak nafas dan nyeri dada. Berdasarkan jenis histopatologi, jenis yang paling banyak adalah non small cell lung carcinoma.  Sedangkan, berdasarkan staging dengan rata-rata staging yaitu staging IV.
Clinicopathological Characteristics of Breast Cancer at Cibabat Regional General Hospital in 2022–2023 Rachmawati, Meike; Acang, Nuzirwan; Purbaningsih, Wida; Robian, Rian; Nugraha, Adhi; Melati, Rina; Aryanti, Aryanti; Anugrah, Aninditya Putri; Laila, Nazmy Noor
Global Medical & Health Communication (GMHC) Vol 12, No 1 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i1.13462

Abstract

Breast cancer is the most common malignancy found in women throughout the world and is the fifth leading cause of cancer death in the world. Cibabat Regional General Hospital is one of the places for breast cancer examination and treatment in West Java. This study aims to determine the clinical and histopathological features at Cibabat Regional General Hospital. The method used in this research is descriptive-analytic with a total sampling technique using secondary data obtained from the medical records of Cibabat Regional General Hospital patients from 2022 to June 2023. The results show that most cases of breast cancer at Cibabat Regional General Hospital occur in those aged 45–54 (32.3%), left breast (52.1%), grade 3 (44.8%), histopathological type invasive carcinoma of no special type (75%), lymph node status unknown (88.5%), negative lymphovascular invasion (43.7%), and fat invasion status unknown (68.7%). The conclusion is that breast cancer cases at Cibabat Regional General Hospital mainly occur in patients of productive age with a high grade and predominantly in the left breast, with the most common type being invasive carcinoma of no particular type.
Histopathological Review of Granuloma in Diagnosis of Tuberculosis Lymphadenitis (TBL) Purbaningsih, Wida; Rachmawati, Meike; Triyani, Yani; Rahmi, Fadhilat Sabila
Global Medical & Health Communication (GMHC) Vol 11, No 3 (2023)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v11i3.12742

Abstract

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis and is the second leading cause of death from an infectious disease. Indonesia has the highest TB cases in West Java, East Java, and Central Java. Tuberculosis lymphadenitis (TBL) represents about 30–40% of cases of extrapulmonary tuberculosis. The study aimed to study the clinical and histopathological characteristics of TBL patients. The research design in this study used an exploratory, descriptive method. Data was taken from Al Islam Hospital Bandung as medical records from January 2019 to December 2020. The result showed that TBL primarily affects patients aged 6–11 years (28%), male gender (57%), patients not working (25%), and those residing in the East Bandung area (34%). Histopathological appearance showed granulomas of caseous necrosis, epithelioid cells, and Langhan's cells, indicated by types 1, 2, and 3. The most common type was type 1 (47%), which was more widely distributed in the right neck (46%) with size 1–3 cm. In conclusion, the frequency of TBL is higher in boys aged 6–11 years, residents of the East Bandung area, and patients who did not work. Well-formed granuloma of enlarged lymph nodes in the right neck with size 1–3 cm is most commonly found in TBL.
Co-Authors Adhi Nugraha Adli Giardin Agly Adithya Agly Adithya, Agly Aida Fitriyane Hamdani Aida Fitriyane Hamdani Aida Ajeng Kartika Annisa Humairra Annisa Rahmah Furqaani Anugrah, Aninditya Putri Aryanti Aryanti Aurora Rahma Koesdinar Budiman , Budiman Chirgo Rahmat Basdiwo Della Desliana Diemas Abdurahman Hernawan Diyana Djatnika Setiabudi Enggar Hestu Enggar Hestu, Enggar Fani Amalia Putri Herri S. Sastramihardja Ida Parwati Ismet Muchtar Nur Laila, Nazmy Noor Lelly Yuniarti Listya Hanum Siswanti Lukman Hakim Muttaqien Maya Tejasari Meike Rachmawati Melati, Rina Miranti Kania Dewi Muhammad Faris Rizki Nadiyya Yasmin Nuzirwan Acang R.B. Soeherman Herdiningrat Rahmi, Fadhilat Sabila Raihan Zakki Ratna Damailia Retno Ekowati Rika Nilapsari Robian, Rian Sadeli Masria Salsabila Adinda Rahman Sara Shafira Sayyidah Fauziyah Siti Annisa Devi Trusda, Siti Annisa Devi Siti Salma Nurhaliza Fitriadi Siti Salma Nurhaliza Fitriadi Suryani, Yani Dewi Susan Fitriyana Titik Respati Tryando Batara Tursina, Alya Umar Islami Widhy Yudistira Nalapraya Widhy Yudistira Nalapraya Winni Maharani Yani Dewi Suryani Yani Triyani Yani Triyani Zikri Resa Hasrian Zulfi Noor Fadia