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All Journal MNJ (Malang Neurology Journal) Medicinus : Jurnal Kedokteran Majalah Kedokteran Neurosains Eduvest - Journal of Universal Studies Neurona Acta Neurologica Indonesia
Vivien Puspitasari, Vivien
Department Of Neurology, Faculty Of Medicine, University Of Pelita Harapan Siloam Hospital Lippo Village
Aerospace Engineering Computer Science & IT Health Professions Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Factors Affecting Progonosis in Tuberculous Meningoencephalitis Puspitasari, Vivien; Sutanto, Anyeliria; Stevano, Reza; Djuanda, Gerald
Acta Neurologica Indonesia Vol. 1 No. 01 (2023): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69868/ani.v1i01.7

Abstract

Introduction: Cases of tuberculosis is still highly prevalent in the world, including Indonesia.Tuberculous meningoencephalitis (TBME) is the most severe form of tuberculosis. This study aims to establish the factors affecting prognosis in TBME. Objective: To Identify the clinical factors that affect the prognosis of tuberculous meningoencephalitis patients. Material and Methods: This is cross-sectional study evaluating factors (clinical features, imaging, and treatment) affecting prognosis in TBME patients who underwent treatment in Siloam Hospitals Lippo Village. Univariate analyses was done, followed by bivariate analyses with logistic regression to compare factors between good (Glasgow outcome scale [GOS] 4-5) and poor (GOS 1-3) prognosis. Results and Discussion: 64 patients were included. On univariate analysis, significant differences was found between Glasgow coma scale (GCS) scores (p=0.012), clinical features of meningeal irritation (p=0.004), findings of hydrocephalus (p=0.023) and vasculitis/infarction (p=0.020) on imaging, antibiotic use (p=0.013), and MRC grading (p=0.008). On logistic regression, 4 factors were found to be significant: headache (OR 5.398 95% CI 1.165-25.008, p=0.031), meningeal irritation (OR 0.146 95% CI 0.026-0.813, p=0.028), hydrocephalus (OR 0.167 95% CI 0.032-0.881, p=0.035), and antibiotic use (OR 0.155 95% CI 0.034-0.717, p=0.017). Conclusion: Clinical manifestations of meningeal irritation and altered consciousness, imaging findings of hydrocephalus and vasculitis/infarction, and antibiotic usage is associated with poor prognosis, while presence of headache is associated with a better prognosis.
Isolated Abducens Nerve Palsy: A Case Report of Cerebral Pseudocyst of Dorello’s Canal Puspitasari, Vivien; Japutri, Josephine; Solansa, Tracy; Cenweikiawan, Anderson
Medicinus Vol. 15 No. 1 (2025): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v15i1.10768

Abstract

Background: Abducens nerve is the second longest intracranial path out of all of the cranial nerves. Abducens nerve pasly had a prevalence 11.3/100.000 and mostly seen in adults. Isolated abducens nerve palsy due to neoplastic lesion are rare and mostly related to skull base tumor. Case Description: We present a case of 57 years old woman with complaints of red right eye and worsening headache associates with diplopia on the right lateral gaze for three days prior admission. She was later diagnosed with isolated abducens nerve palsy associated to neoplasm cause in Dorello’s canal. Patient was then discharged with symptomatic therapy and educated for head posturing and avoid triggers. Conclusions: Abducens nerve palsy is the most common isolated ocular nerve palsy. The incidence of mass formation such as neoplastic lesion or cyst are rare.
Co-Authors Amiruddin Aliah, Amiruddin Budhianto Suhadi Cahyono Kaelan, Cahyono Cenweikiawan, Anderson Chandra, Anastasya Djuanda, Gerald Eka J. Wahjoepramono Evelyn Yunita Harsono, Ivan William Hartoyo, Vinson Ilhamjaya Patellongi Ivan William Harsono Jan S. Purba, Jan S. Japutri, Josephine Julius July Ketaren, Retno Jayantri M.T. Siahaan, Yusak Made Agus Mahendra Inggas, Made Agus Mahendra Nathania Victoria Stevina Pangestu, Aristo Pangestu, Aristo Rinaldi Situmeang, Rocksy Fransisca V. Solansa, Tracy Stevano, Reza Stevina, Nathania Victoria Sutanto, Anyeliria Syarifuddin Wahid Tiffani, Pamela Wahyoepramono, Julianta Widjaja, Devita Yong, Yee Wen