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All Journal JURNAL KIMIA SAINS DAN APLIKASI SAINTIFIK@ : Jurnal Pendidikan MIPA Medical Laboratory Technology Journal Journal of Health Sciences ad-Dawaa : Journal of Pharmaceutical Sciences Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Jurnal Pengabdian Masyarakat Indonesia Journal of Indonesian Medical Laboratory and Science (JoIMedLabS) Pharmaceutical And Biomedical Sciences Journal (PBSJ) Jurnal Kolaboratif Sains Jurnal Pengabdian Masyarakat dan Riset Pendidikan Jurnal Medicare
Asbar Tanjung
Department Of Medical Laboratory Technologist, STIKes Prima Indonesia
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Antimicrobial Activities of Synthesized Silver Nanoparticles using Ethanol and Water Extract of Mirabilis Jalapa Tunas Alam; Frida Octavia Purnomo; Asbar Tanjung
Jurnal Kimia Sains dan Aplikasi Vol 24, No 3 (2021): Volume 24 Issue 3 Year 2021
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3116.302 KB) | DOI: 10.14710/jksa.24.3.70-76

Abstract

The focus of this study was to compare the antimicrobial activity of silver nanoparticles (AgNPs) synthesized using ethanol extracts (AgNPE) and water extracts (AgNPA) from four o’clock flowers (Mirabilis jalapa) against Staphylococcus aureus. AgNPs were characterized by UV-Vis diffraction, FTIR, SEM, and X-rays. UV-Vis analysis showed that AgNPA has an SPR band of about 460 nm and 530 nm for AgNPE, which proves the characteristics of the absorbance area of AgNPs. SEM images of AgNPE and AgNPA show a cuboid shape with a mean diameter of 80 and 30 nm, respectively and well dispersed. The response to the presence of polysaccharide biomolecules involved in forming AgNPs was analyzed using a Fourier transform infrared spectrometer. The result was that AgNPA and AgNPE have different reducing agents. The plant extracts, AgNPE and AgNPA, were studied for their antimicrobial activity against Staphylococcus aureus. The result was that both AgNPA and AgNPE showed good activity and showed that AgNPA with less inhibition was more effective than AgNPE.
Sosialisasi Pemanfaatan Minyak Kelapa Murni (Virgin coconut oil) di Desa Lenggah Sari Ing Mayfa Br Situmorang; Nahdiyatul Mukaromah; Asbar Tanjung; Ardy Tanfil. T
Jurnal Pengabdian Masyarakat Indonesia Vol 3 No 2 (2023): JPMI - April 2023
Publisher : CV Infinite Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52436/1.jpmi.1012

Abstract

Minyak kelapa murni merupakan salah satu minyak yang sejak lama dimanfaatkan oleh masyarakat Indonesia, manfaatnya yang banyak seperti antibakteri dan antiinflamasi juga telah dibuktikan secara ilmiah. Berdasarkan manfaat tersebut maka Minyak kelapa murni atau yang juga dikenal dengan virgin coconut oil dapat dimanfaatkan sebagai bahan dasar pembuatan sabun dan minyak alternativ untuk pemijatan. Desa dengan jumlah pohon kelapa yang banyak merupakan tempat yang berpotensi untuk mengembangkan minyak kelapa murni, berdasarkan hasil observasi diketahui Desa Lenggah Sari yang terletak di kecataman Cabangbungu merupakan salah satu desa yang memiliki sumber daya alam berupa pohon kelapa dalam jumlah yang relatif banyak, berdasarkan hal tersebut maka perlu dilakukan sosialisasi di Desa Lenggah Sari terkait dengan pemanfaatan minyak kelapa murni dalam bidang kesehatan. Hasil Pre Test menunjukkan bahwa masyarakat desa Lenggah Sari belum memahami terkait pemanfaatan minyak kelapa murni dalam bidang kesehatan terutama sebagai bahan dasar pembuatan sabun dan sebagai minyak alternatif untuk aktivitas pemijatan. Setelah dilakukan sosialisasi diketahui pemahaman masyarakat terkait pemanfaatan minyak kelapa murni meningkat, hal tersebut diketahui berdasarkan hasil olah statistik dengan software SPSS versi 26.
Efektivitas Ekstrak Daun Patilawa (Lantana Camara Linn) sebagai Insektisida Terhadap Kematian Aedes Sp: Effectiveness of Patilawa Leaf Extract (Lantana camara Linn) as an Insecticide Against Aedes spp. Mortality Muhamad Sultanul Aulya; Asbar Tanjung
Jurnal Kolaboratif Sains Vol. 7 No. 8: Agustus 2024
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jks.v7i8.5966

Abstract

Aedes sp merupakan vektor dari virus dengue dengan dua spesies yaitu nyamuk Aedes aegypti dan nyamuk Aedes albopictus yang tersebar di seluruh dunia. Aedes aegypti dan Aedes albopictus merupakan vektor penular penyakit DBD (Demam Berdarah Dengue). Penyakit demam berdarah dengue berkembang secara drastis pada beberapa tahun terakhir. DBD hampir ditemukan di seluruh daerah belahan dunia yang memiliki iklim tropis dan subtropis, terutama pada daerah perkotaan dan semiurban. Tujuan penelitian ini adalah untuk mengekplorasi penggunaan Daun patilawa (Lantana camara Linn) sebagai insektisida alami terhadap nyamuk Aedes sp. Penelitian dilakukan dengan metode eksperimental dengan Rancangan Acak Lengkpa (RAL) 4 perlakuan dan 3 kali pengulangan yaitu variasi konsentrasi 20%, 30%, 40% dan 50%. Kontrol postif yangdigunakan adalah X-Elektrik (transflurin 12,38 g/l)) dan aquadest sebagai kontrol negative. Hasil penelitian menunjukkan ekstrak daun patilawa (Lantana camara Linn) memiliki aktifitas insektisida alami terhadap nyamu Aedes sp pada setiap konsentrasi (20%, 30%, 40% dan 50%), disamping itu hasil penelitian juga menunkkan bahwa efektifitas insektisidal ekstrak daun patilawa (Lantana camara Linn) menunjukkan tren peningkatan efektifitas seiring dengan peningkatan konsentrasi ekstrak. Uji statistik dengan anova satu arah menunjukkan nilai p<0.001 yang berarti perbedaan bermakna pada efektifitas insektisidal pada tiap konsentrasi ekstrak.
Aktivitas Antijamur Ekstrak Biji Kopi Hijau Robusta (Coffea canephora) Terhadap Candida albicans. Ing Mayfa Br Situmorang; Putri Salsadila; Sharfina Maulidayanti; Asbar Tanjung
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol 6, No 2 (2024)
Publisher : UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v6i2.39149

Abstract

Acne is a disease that can be caused by bacteria, one of which is Staphylococcus epidermidis. Acne can be treated with active compounds derived from natural ingredients such as cucumbers and tomatoes. Gel masks peel off. This study aims to determine the average diameter of the inhibition zone, the difference in the average diameter of the inhibition zone, and the antibacterial activity of the peel-off from a mixture of cucumber (Cucumis sativus) and tomato  (Solanum lycopersicum) with a concentration of 5%, 10 %, 15%, 20% against  Staphylococcus epidermidis. This experimental study uses a Completely Randomized Design (CRD) consisting of one factor and 6 levels. The results showed that the average diameter of the inhibition zone of the anti-acne peel-off gel mask preparation of cucumber and tomato extracts against Staphylococcus epidermidis at a concentration of 5%, 10%, 15% and 20% were 16.38 mm, respectively. ; 24.88 mm; 29.88 mm and 34.88 mm. There was a significant difference in the average diameter of the inhibition zone of the peel off mixture of cucumber and tomato extracts with a concentration of 5%, 10%, 15%, and 20%; against Staphylococcus epidermidis. gel mask preparation peels off from a mixture of cucumber and tomato extracts against Staphylococcus epidermidis at a concentration of 5%, 10% concentration, 15% concentration and 20% concentration, namely strong, very strong, very strong and very strong.   Keywords: staphylococcus epidermidis, gel mask peel-off, cucumber, tomato
Analysis of Hematological Examination Results in Pulmonary Tuberculosis (TB) Patients Undergoing Intensive Phase Anti-Tuberculosis Drug Therapy Tanjung, Asbar
Jurnal Ilmiah Kesehatan Vol 17 No 03 (2024): Jurnal Ilmiah Kesehatan (Journal of Health Science) 
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/jhs.v17i03.5792

Abstract

The intensive phase of anti-tuberculosis (TB) drug therapy consists of a combination of antibiotics, including Isoniazid (INH), Rifampicin (RIF), Pyrazinamide (PZA), and Ethambutol (EMB). The primary goal of this therapy is to inhibit the growth and spread of Mycobacterium tuberculosis, preventing its migration from the lungs to other organs. However, intensive-phase therapy may result in both major and minor side effects. This study aims to analyze the hematological profiles of pulmonary TB patients undergoing intensive-phase anti-tuberculosis treatment. The respondents were pulmonary TB patients recruited from primary healthcare centers within the East Bekasi District, Bekasi City. Those who met the sample criteria underwent hematological examinations, including hemoglobin (Hb), hematocrit (HCT), red blood cell count, white blood cell count, and platelet count. The tests were conducted using the electrical impedance method with a hematology analyzer. The hematological examination revealed a trend of low hemoglobin levels, with the average Hb recorded at 11.98 ± 8.65 g/dL. Additionally, abnormal blood parameters were observed, with 33.3% of patients experiencing erythropenia, 57% showing thrombocytopenia, 33% presenting leukopenia, and 20% exhibiting leukocytosis. These findings confirm that intensive- phase anti-tuberculosis therapy affects the hematological profiles of pulmonary TB patients, highlighting the need for close monitoring during treatment.
Analysis of Serum Creatinine Levels, Blood Pressure and Grade of Hypertension of Chronic Disease Management Program Participants Tanjung, Asbar; Nurhidayah, Ika; Maulidayanti, Sharfina; Br Situmorang, Ing Mayfa
Medical Laboratory Technology Journal Vol. 10 No. 2 (2024): December
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v10i2.619

Abstract

Indonesia is one of the countries with the highest number of cases of hypertension in the world; the predominant patient is the elderly. In some patients with hypertension, increased blood pressure causes impaired salt and creatinine excretion, resulting in poor kidney function. A chronic disease management program is a health care system with a proactive-integrative approach to prevent further complications. The research objective is to analyze serum creatinine levels, blood pressure, and hypertension grade and determine the relationship between serum creatinine and blood pressure in chronic disease management program participants. The study subjects, 73 participants with hypertension, were obtained by purposive sampling. Patient data and hypertension grade were obtained from medical records; an auto chemistry analyzer analyzed serum creatinine. Data were analyzed using the Pearson correlation test using SPSS. Participants with hypertension fall into the elderly age (60-69 years), totalling 31 (42%); pre-elderly age (45–59 years) includes 28 (38%); and high-risk elderly age (>70 years) includes 14 (19%). Most of the participants (40 participants) fell into hypertension stage II, followed by hypertension stage I (25 participants), and only 8 participants fell into the elevated category. The mean serum creatinine of participants with Elevated blood pressure criteria was 0.89±0.178, Hypertension grade I 0.91±0.322, and hypertension grade II 0.99±0.269, illustrating a trend of increasing serum creatinine levels due to higher blood pressure criteria. Pearson correlation test shows a significant correlation between both systolic blood pressure with serum creatinine levels (p<0.05, r=0.2) and diastolic blood pressure with serum creatinine levels (p=0.007, r=0.342). There was a trend of increasing serum creatinine levels corresponding to the hypertension grade in participants. Blood pressure was significantly correlated with serum creatinine, clearly confirming that an increase in blood pressure may followed by an increase in serum creatinine.
EFEKTIVITAS EKSTRAK DAUN PATILAWA (LANTANA CAMARA LINN) SEBAGAI INSEKTISIDA TERHADAP KEMATIAN NYAMUK AEDES SP Aulya, Muhammad Sultanul; Tanjung, Asbar
SAINTIFIK@: Jurnal Pendidikan MIPA Vol 9, No 2 (2024): SAINTIFIK@: Jurnal Pendidikan MIPA EDISI OKTOBER 2024
Publisher : Universitas Khairun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33387/saintifik.v9i2.8504

Abstract

Aedes sp merupakan vektor dari virus dengue dengan dua spesies yaitu nyamuk Aedes aegypti dan nyamuk Aedes albopictus yang tersebar di seluruh dunia. Aedes aegypti menempati habitat domestik terutama di dalam rumah dan penampungan air yang tidak berhubungan langsung dengan tanah, sedangkan Aedes albopictus berkembang biak pada lubang-lubang pohon, drum, ban bekas yang terdapat di luar rumah. Aedes aegypti dan Aedes albopictus merupakan vektor penular penyakit DBD (Demam Berdarah Dengue). Penyakit demam berdarah dengue berkembang secara drastis pada beberapa tahun terakhir. DBD hampir ditemukan di seluruh daerah belahan dunia yang memiliki iklim tropis dan subtropis, terutama pada daerah perkotaan dan semiurban. Pada tahun 2010 sampai 2015 beberapa wilayah anggota WHO seperti Amerika, Brazil dan Hawai dilaporkan terjadi peningkatan kasus dari 2,2 juta di tahun 2010 sampai 3,2 juta kasus di tahun 2015. Kasus DBD pada tahun 2018 berjumlah 65.602 kasus, dengan jumlah kematian sebanyak 467 orang. Jumlah tersebut menurun dari tahun sebelumnya, yaitu 68.407 kasus dan jumlah kematian sebanyak 493 orang. Angka kesakitan DBD tahun 2018 menurun dibandingkan tahun 2017, yaitu dari 26,10 menjadi 24,75/100.000 penduduk.Tujuan penelitian ini adalah untuk mengekplorasi penggunaan Daun patilawa (Lantana camara Linn) sebagai insektisida alami terhadap nyamuk Aedes sp. Penelitian dilakukan dengan metode eksperimental dengan Rancangan Acak Lengkpa (RAL) 4 perlakuan dan 3 kali pengulangan yaitu variasi konsentrasi 20%, 30%, 40% dan 50%. Kontrol postif yangdigunakan adalah X-Elektrik (transflurin 12,38 g/l)) dan aquadest sebagai kontrol negative.Hasil penelitian menunjukkan ekstrak daun patilawa (Lantana camara Linn) memiliki aktifitas insektisida alami terhadap nyamu Aedes sp pada setiap konsentrasi (20%, 30%, 40% dan 50%), disamping itu hasil penelitian juga menunkkan bahwa efektifitas insektisidal ekstrak daun patilawa (Lantana camara Linn) menunjukkan tren peningkatan efektifitas seiring dengan peningkatan konsentrasi ekstrak. Hasil uji statistik dengan Anova satu arah menunjukkan nilai p0.001 yang berarti perbedaan bermakna pada efektifitas insektisidal pada tiap konsentrasi ekstrak.
Validasi Simplisia dan Ekstrak Kulit Batang Wilalondahi (Archidendron lucyi) sebagai Bahan Aktif Obat Tradisional Devin, Devin; Ali, Nur Fitriana Muhammad; Tanjung, Asbar; Ramadan, Leski; Kurniawan, Yedith; Haris, Restu Nur Hasanah; Irwan, Irwan
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 6 No 01 (2024): HERCLIPS VOL 06 NO 01
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/herclips.v6i01.8796

Abstract

Penelitian ini bertujuan untuk memvalidasi penggunaan empiris kulit batang Wilalondahi (Archidendron lucyi) yang telah lama dimanfaatkan sebagai agen hemostatik dan penyembuh luka oleh masyarakat Sulawesi Tenggara. Mengingat hingga saat ini belum terdapat informasi terkait komposisi dan karakteristik kulit batang tumbuhan Wilalondahi dalam Monograf Farmakope Herbal Indonesia, maka penelitian dapat menambahkan data baru mengenai aspek fisik, kimia, dan fitokimia dari simplisia kulit batang tersebut sebagai kontribusi terhadap pengembangan informasi tanaman herbal di Indonesia. Hasil Penelitian ini menunjukkan bahwa simplisia kulit batang Wilalondahi memiliki karakteristik berdasarkan parameter spesifik dan non-spesifik. Parameter spesifik meliputi analisis makroskopik, yang menunjukkan warna putih kecoklatan, bau khas, rasa hambar, dan tekstur serbuk kasar; analisis mikroskopik, yang mengidentifikasi butir amilum, rambut penutup, dan berkas pembuluh sebagai fragmen pengenal; serta kadar sari larut etanol dengan nilai rata-rata 7%, yang memenuhi standar Farmakope Herbal Indonesia (≥6,7%). Parameter non-spesifik mencakup kadar air sebesar 7,3%, kadar abu total 8,4%, dan kadar abu tidak larut asam 1,1%, yang keseluruhannya sesuai dengan batas standar (≤10% untuk kadar air, ≤10,2% untuk kadar abu total, dan ≤2% untuk kadar abu tidak larut asam). Skrining fitokimia mengungkap keberadaan flavonoid dan tanin sebagai senyawa bioaktif utama, yang berpotensi memiliki aktivitas antiinflamasi dan hemostatik, mendukung potensi kulit batang Wilalondahi sebagai bahan baku obat herbal.
Aktivitas Antibakteri Bakteri Asam Laktat yang diisolasi dari Makanan Tradisional Dangke, Kabupaten Enrekang, Sulawesi Selatan Tanjung, Asbar; Tanfil, Ardi; Nur, Jumriah
Ad-Dawaa: Journal of Pharmaceutical Sciences
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v7i2.52549

Abstract

Introduction: Lactic acid bacteria (LAB) produce lactic acid as the end product of carbohydrate metabolism. LAB is known to have benefits, including balancing the microflora in the gut, is bacteriostatic, and is also reported to be able to stimulate the immune system. LAB can be isolated and characterized from various food products spread throughout Indonesia. Dangke is a food product in the form of processed cow's milk which is traditionally produced by the people of Enrekang Regency, South Sulawesi. Aims: To isolate and explore the characteristics of LAB both phenotype and genotype isolated from dangke as well as in vitro studies on the potential and mechanisms of their inhibition of the growth of pathogenic bacteria. Method: Research started with the process of collecting samples of dangke in Enrekang Regency, isolation and identification of indigenous LAB in dangke samples, characterization and continued with in vitro studies on the potential of LAB from dangke to inhibit bacterial growth. Results: LAB isolated from dangke macroscopic characteristics in the form of round colonies, mucoid texture, entire edge, elevation convex and translucent with a size of 2.2 mm. Microscopic characteristics in the form of rod-shaped gram-positive bacteria. Isolated LAB has the ability to grow in extreme conditions approaching intestinal conditions, namely growing in an environment with an acidic pH range of 3-5 and tolerant to bile salts. Secondary metabolites produced can inhibit the growth of S. aureus bacteria in vitro. Conclusion: LAB isolated from dangke have demonstrated significant potential for probiotic and antibacterial applications.
GAMBARAN ALKOHOL DALAM URIN PEMINUM ALKOHOL DENGAN METODE KALIUM DIKROMAT Situmorang, Ing Mayfa; Ladyka Viola A.A; Asbar Tanjung; Athifah Febry Alfiani
Jurnal Medicare Vol. 4 No. 3: JULY 2025
Publisher : Rena Cipta Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62354/jurnalmedicare.v4i3.234

Abstract

Alcohol detection methods have gone through significant development with various methods such as gas chromatography, strip test, and potassium dichromate. Potassium dichromate method is a simple method to detect alcohol in urine with the principle of oxidation reaction between alcohol and potassium dichromate in an acidic atmosphere between alcohols forming a green color. This study aims to identify alcohol in the urine of male alcohol drinkers aged 17-50 years using the potassium dichromate method. The research method used was descriptive experimental. The population in this study were all alcohol drinkers in Cakung Timur Village who met the exclusion and inclusion criteria. The sample used in this study was 30 samples. The sampling technique used was purposive sampling. The method used is potassium dichromate method. The results showed that the potassium dichromate method can detect blood alcohol content through urine obtained 29 respondents (98.7%) positive and 1 respondent (1.13%) negative.
Co-Authors Ali, Nur Fitriana Muhammad Ardy Tanfil. T Athifah Febry Alfiani Br Situmorang, Ing Mayfa Devin, Devin Frida Octavia Purnomo Haris, Restu Nur Hasanah Ing Mayfa Br Situmorang Ing Mayfa Br Situmorang Irwan Irwan Jumriah Nur, Jumriah Kurniawan, Yedith Ladyka Viola A.A Ladyka Viola Aulia Armawan Maulidayanti, Sharfina Muhamad Sultanul Aulya Muhammad Sultanul Aulya Nahdiyatul Mukaromah Noni Farah Nurhidayah, Ika Putri Salsadila Ramadan, Leski Sharfina Maulidayanti Situmorang, Ing Mayfa Tanfil, Ardi Tunas Alam