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All Journal Syntax Literate: Jurnal Ilmiah Indonesia Journal of Public Health Sciences Journal of Vocational Health Science
Ade Irma
Fakultas Teknologi Kesehatan, Universitas Megarezky, Makassar, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Potential of Harum Manis Mango (Mangifera Indica L.) Seed Extract for Nosocomial Infections Wahdaniar; Imran Pashar; Miladiarsi; Ade Irma
Journal of Public Health Sciences Vol. 2 No. 02 (2023): Journal of Public Health Sciences
Publisher : The Indonesian Institute of Science and Technology Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56741/jphs.v2i02.213

Abstract

Nosocomial infections occur in hospitals and attack patients who are in the recovery process and have low immunity. The emergence of nosocomial conditions in the hospital environment is caused by bacteria and moist objects or materials, especially in the operating room and even the treatment room for children and babies. One type of bacteria that causes the infection is Pseudomonas aeruginosa. P. aeruginosa has been recognized as an irreversible problem in hospitals due to resistance to 3 antibiotic classes. The content of sweet mango seeds has a high phytochemical content in the form of steroid compounds, terpenoids, flavonoids, alkaloids, phenolics, tannins and saponins. This study aimed to determine the potential of sweet mango seed extract against nosocomial infections. The research method is quantitative experimental, using ethanol extract of sweet fragrant mango seeds with well diffusion and dilution tests (MIC and MBC). The results of the antibacterial activity test measured the inhibition zone formed and tested MIC and MBC. MIC value of sweet fragrant mango seed extract showed at 1.56 mg/mL and 0.78, and at MBC value of 25 mg/mL and 50 mg/mL. The results of sweet fragrant mango seed extract have the potential to be developed as an antibacterial agent, especially against nosocomial infections.
Efektivitas Antimikroba Bakteri Probiotik Dari Usus Itik Pedaging Anas Domesticus terhadap Pertumbuhan Vibrio Spp Ade Irma; Wahdaniar Wahdaniar; Miladiarsi Miladiarsi
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.195 KB) | DOI: 10.36418/syntax-literate.v7i8.9308

Abstract

Telah dilakukan penelitian “Efektivitas Antimikroba Bakteri Probiotik dari Usus Itik Pedaging Anas domesticus terhadap Pertumbuhan Vibrio spp.”. Penelitian ini bertujuan untuk mengetahui kemampuan bakteri probiotik dari usus itik pedaging Anas domesticus berdasarkan perbedaan lama inkubasi kultur probiotik terhadap pertumbuhan Vibrio spp. Kemampuan dari isolat H terhadap pertumbuhan Vibrio spp. dapat diketahui dengan melakukan uji daya hambat. Berdasarkan uji daya hambat yang telah dilakukan menunjukkan bahwa isolat H memiliki kemampuan dalam membunuh atau bersifat bakteriosidal terhadap pertumbuhan Vibrio spp dengan membentuk zona bening disekitar blank disk. Indikasi ini membuktikan bahwa isolat H mampu menghasilkan senyawa metabolit selama pertumbuhannya. Lama inkubasi kultur isolat H berpengaruh terhadap senyawa metabolit yang dihasilkan. Produksi optimum senyawa metabolit berada pada kondisi kultur 48 jam yang ditunjukkan dengan adanya penambahan zona bening disekitar blank disk. Isolat H juga memiliki kemampuan yang tinggi terhadap pertumbuhan Vibrio harveyi dibandingkan dengan V. parahaemolyticus dan V. cholera.
Karakterisasi Mikrobiota Mulut Penghasil Senyawa Antimikroba: Laboratory Research Ade Irma; Juniati Binti Lukman; Arafah Nurfadillah
Journal of Vocational Health Science Vol. 1 No. 1 (2022): Journal of Vocational Health Science (JOVAS)
Publisher : Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31884/jovas.v1i1.10

Abstract

Microbes or microorganisms are organisms that have a size so small that they can only be seen with the help of a microscope. Microbes are widespread in nature and can be found anywhere. Mikroba can be settled in the soil, water, air, there is even one that is found in living beings (on living tissues). The microbiome is a community of microbes or microorganisms in this case bacteria, archae, fungi, viruses that live above or within other living organisms. The human-associated microbiome is called the microbiota. The presence of microbes in the body can cause interactions that are beneficial, detrimental or some are neutral in nature. The use of antibiotics whose nature is synthetic can cause a negative effect for health besides that it can also cause  resistance properties.  Therefore, it is necessary to have a type of antibiotic that comes from living beings.  The sample used in this study was a bacterial isolate in the oral cavity (swab results) the next stage was characterization through biochemical tests.  The results of characterization through biochemical tests showed that isolates of oral microbiota bacteria showed the species Streptococcus sp. which has the ability to produce antimicrobial compounds.
Potensi Mikrobiota Mulut Genus Streptococcus Penghasil Senyawa Antimikroba : Laboratory Research Ade Irma; Juniati Binti Lukman; Arafah Nurfadillah
Journal of Vocational Health Science Vol. 2 No. 1 (2023): Journal of Vocational Health Science (JOVAS)
Publisher : Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31884/jovas.v2i1.11

Abstract

Mikrobioma yang berasosiasi dengan manusia disebut mikrobiota. Berbagai jenis mikrobiota mulut dapat menguntungkan dan membantu sistem pencernaan serta membantu sistem imun tubuh karena menghasilkan berbagai senyawa kimia yang bermanfaat melawan kuman patogen. mikrobiota mulut yang berperan sebagai bakteri probiotik, salah satunya yang tergolong dalam genus Streptococcus. Tujuan penelitian ini untuk mengetahui potensi microbiota mulut khususnya genus Streptococcus penghasil senyawa antimikroba. Metode penelitian yang digunakan adalah kuantitatif eksperimental berupa aktivitas antibakteri diukur zona hambat yang terbentuk. Hasil uji menunjukkan bahwa dari 40 swab diperoleh 17 isolat yang dapat menghambat pertumbuhan bakteri uji Staphylococcus aureus dan Escherichia coli dengan ukuran zona hambat yang paling besar yaitu 9,35 mm terhadap S. aureus dan terkecil 7,00 mm. sementara pada bakteri uji E.coli terdapat zona hambat yang dihasilkan sekitar 9,00 mm dan hasil pengukuran yang paling kecil adalah sekitar 7,00 mm. dari hasil pengujian memperlihatkan bahwa microbiota mulut genus Streptococcus berpotensi menghasilkan senyawa antimikroba.
Co-Authors Arafah Nurfadillah Imran Pashar Juniati Binti Lukman Miladiarsi Miladiarsi Miladiarsi W, Wahdaniar