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All Journal Jurnal Kesehatan Masyarakat Nexus Kedokteran Klinik Jurnal Riset Kesehatan The Indonesian Biomedical Journal Smart Society Empowerment Journal
Dyonisa Nasirochmi Pakha
Fakultas Kedokteran Universitas Sebelas Maret
Humanities Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health Other

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Hubungan Kecenderungan Gangguan Kepribadian Antisosial dengan Adiksi Online Game pada Remaja Laki-laki Pengunjung Game Centre di Surakarta Dyonisa Nasirochmi Pakha; Djoko Suwito; Zulaika Nur Afifah
Nexus Kedokteran Klinik Vol 3, No 3 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.046 KB)

Abstract

Background: Online gaming addiction has become a health issue and brings a negative impact, especially in adolescents. One of the factors that predispose online gaming addiction is the tendency of antisocial personality disorder. The tendency of antisocial personality disorder has symptoms that can lead to addictive attitude. This study aims to determine the correlation between the tendency of antisocial personality disorder and online games addiction in adolescents game center visitor in Surakarta. Methods: This study used an observational analytic with cross sectional approach in ten game centers in Surakarta. Sampling was carried out in July and September 2014 using the inclusion and exclusion criteria that have been determined. The sampling technique used was the total sampling. The independent variable was the tendency of antisocial personality disorder that was measured by The Manson Evaluation Test questionnaire, while the dependent variable was online gaming addiction that was measured by Online Game Addiction Indonesia questionnaire. The data analysis used was Pearson correlation test which Kolmogorov-Smirnov data normality test was previously conducted. Results: This study got 53 samples with a mean age of 17 years, the average score of the tendency of antisocial personality disorder was 29.989.32, and the average score of online gaming addiction was 18.385.90. Data normality test showed a significance value of the tendency of antisocial personality disorder = 0.061 (p> 0.05) and for online gaming addiction = 0.200 (p> 0.05), which means that the data distribution of two variables were normal. Pearson correlation test results demonstrate the value of the Pearson correlation coefficient (r) 0562 with a significance value = 0.000 (p <0.05), which means that there was a moderate correlation between the tendency of antisocial personality disorder and online gaming addiction in adolescents game center visitor in Surakarta and the correlation was statistically significant. Conclusions: There is a correlation between the tendency of antisocial personality disorder and online gaming addiction in adolescents game center visitor in Surakarta. Keywords: The tendency of antisocial personality disorder, online gaming addiction, adolescents
Edukasi Penyakit Diabetes Melitus dan Cara Pemeriksaan Glukosa Darah Secara Mandiri Tri Agusti Sholikah; Ratih Puspita Febrinasari; Dyonisa Nasirochmi Pakha
Smart Society Empowerment Journal Vol 1, No 2 (2021): Smart Society Empowerment Journal
Publisher : Fakultas Kedokteran UNS

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (636.245 KB) | DOI: 10.20961/ssej.v1i2.49802

Abstract

Pendahuluan: Diabetes mellitus (DM) merupakan salah satu penyakit metabolik kronis yang masih menjadi perhatian di dunia. Penyakit ini ditandai dengan tingginya kadar glukosa pada sirkulasi darah atau disebut dengan hiperglikemia. Deteksi dini penyakit DM dan pemantauan kadar glukosa darah pada penderita DM sangatlah penting untuk dilakukan. Hal tersebut dikarenakan apabila kadar glukosa darah sangat tinggi atau tidak terkontrol akan menyebabkan terjadinya komplikasi serius diberbagai organ tubuh, sehingga dapat meningkatkan morbiditas dan mortalitas pasien. Saat ini telah tersedia alat pemeriksaan glukosa darah yang mudah digunakan masyarakat yaitu glukometer. Namun, nampaknya masih banyak masyarakat yang belum terampil menggunakannya. Selain itu banyak masyarakat yang belum memahami penyakit DM secara holistik sehingga perlu dilakukan kegiatan pengabdian masyarakat tentang penyakit DM.Metode: Metode pengabdian masyarakat ini adalah edukasi tentang penyakit Diabetes Melitus secara holistik melalui penyebaran video di grup-grup Whatsapp, Instagram, Facebook dan Youtube. Video edukasi tersebut terdiri dari 3 buah video, yaitu video tentang penyakit DM secara holistik, video cara penggunaan glukometer untuk memeriksa glukosa darah, dan video tentang DM di era COVID-19. Setelah disebarkan, masyarakat diminta memberikan respon melalui kuesioner. Hasil dan pembahasan: Sebagian besar responden sangat setuju bahwa video yang diunggah membuat mereka menjadi lebih paham mengenai penyakit diabetes melitus dan cara menggunakan glukometer.Kesimpulan: Kegiatan pengabdian kepada masyarakat dapat meningkatkan pengetahuan dan pemahaman masyarakat mengenai penyakit DM dan cara memeriksa glukosa darah secara mandiri dengan glukometer.
The Affecting Factors of Compliance Diabetes Mellitus Type 2 Treatment in Pandemic Era Febrinasari, Ratih Puspita; Solikah, Tri Agusti; Nasirochmi, Dyonisa; Dilma’aarij, Dilma’aarij
KEMAS: Jurnal Kesehatan Masyarakat Vol 17, No 4 (2022)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v17i4.29885

Abstract

Diabetes mellitus (DM) is one of the non-communicable diseases that cause serious health problems. This chronic disease requires lifelong treatment to prevent complications and death. In the pandemic era, DM became comorbid that contributed to the death rate in Covid-19 cases, so that patients with type 2 DM become important to comply with the treatment underway. Aim: This study aimed to evaluate the treatment compliance in patients with DM type 2 at the Purwodiningratan primary health care, Surakarta. Method: This study was conducted in 2020 used an analytical method with crosssectional design. Populations were all of the patients who experience DM type 2, sampling techniques used total sampling with 108 respondents. Univariate, bivariate analysis, and logistic regression were used in this study. Compliance levels measured used the MMAS-8 questionnaire. Result:  The results of this study were obtained from several independent variables that related to compliance with DM type 2 treatment. The descriptive analysis result of patient compliance showed that 70.4% of patients were obedient. The significant variable was the side effects on DM drugs with (OR = -0.44; 95% CI = -0.74 - 0.15; p = 0.003). Conclusion: Most of the patients were adherent to the treatment and the most influencing factor was the side effect of the drug.
THE EFFECTIVENESS OF ETHANOL EXTRACT OF JAMBLANG LEAVES (Syzygium cumini L.) IN INCREASING HDL LEVELS IN WISTAR RATS MODELS OF METABOLIC SYNDROME Muthmainah Muthmainah; Ida Nurwati; Selfi Handayani; Dyonisa Nasirochmi Pakha
Jurnal Riset Kesehatan Vol 12, No 1 (2023): MAY 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jrk.v12i1.9305

Abstract

One of the characteristics of metabolic syndrome (MetS) is the low high-density lipoprotein (HDL) levels. Jamblang leaves (Syzygium cumini L.) contain various phytochemicals, which have antihyperglycemic, antihyperlipidemic, and antioxidant properties. This study aims to demonstrate the effectiveness of ethanol extract of jamblang leaves in increasing HDL levels in the Wistar rats model of MetS. A pretest-posttest with a control group design was conducted using 30 male Wistar rats, divided into five groups randomly, with six rats for each group.  Here, KN means normal control group, K- negative control group, and P1, P2, and P3: treatment groups that were administered the 100 mg/kg/day, 150 mg/kg/day, and 200 mg/kg/day of ethanol extract of jamblang leaves for 28 days, respectively. The rat MetS model was developed by administering the high-fat fructose diet and streptozotocin-nicotinamide. The data were analyzed using paired t-test and one-way ANOVA (α=0.05). This study found that extract administration in P2 and P3 increased HDL levels significantly, but not with the P1 group. However, HDL levels in P1 were significantly higher compared to the K- group. Moreover, increasing the dose was significantly followed by higher HDL levels, although the highest dose did not reach the HDL level as in the KN group.
Red Rice Bran Ethanol Extract Reduces IL-1β as the Risk of Pancreas Fibrogenesis in Type 2 Diabetic Rat Model Wasita, Brian; Yudhani, Ratih Dewi; Pakha, Dyonisa Nasirochmi; Nurrohima, Diana; Muthmainah, Muthmainah; Wiyono, Nanang; Fakurazi, Shariza
The Indonesian Biomedical Journal Vol 17, No 1 (2025)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v17i1.3410

Abstract

BACKGROUND: Oxidative stress and inflammation contribute to pancreatic cell dysfunction that promote insulin resistance in type 2 diabetes (T2D). Red rice bran contains bioactive substances with anti-inflammatory and antioxidant properties which improved insulin resistance in obese mice. However, no studies have explored the potential of ethanol extract of red rice bran (EERRB) to prevent T2D progression, particularly pancreatic fibrosis complications. This study was conducted to investigate the effect of EERRB on inflammation measured with interleukin (IL)-1β and fibrosis of pancreatic tissue in a rat model of T2D. METHODS: Rats were induced with streptozotocin and nicotinamide to induce diabetes, and then separated into five groups. One group received no treatment, while the other four received 9 mg/kg/day acarbose, 165, 330, or 660 mg/kg/day EERRB orally for 21 days. Immunohistochemistry was conducted on pancreas tissues to measure the expression of IL-1β, while pancreatic fibrosis was assessed with Masson’s Trichrome staining.RESULTS: EERRB reduced the expression of pro-inflammatory cytokine, IL-1β, in pancreas tissue in a dose dependent manner. Significantly lower IL-1β expression were found in group receiving 660 mg/kg/day EERRB (10%) compared to diabetic with no treatment group (50%) (p<0.0001). Additionally, the IL-1β expression in the highest dose of EERRB group was comparable to the group receiving acarbose (10%). CONCLUSION: This finding suggests the beneficial effect of EERRB in the hyperglycemic condition that causes oxidative stress through blocking the IL-1β expression, hence alleviating the inflammation in pancreas tissue, and have a tendency in preventing pancreatic fibrosis progression, a process implicated in T2D pathogenesis. KEYWORDS: diabetes, inflammation, pancreatic fibrosis, red rice bran
Co-Authors Brian Wasita Diana Nurrohima Dilma’aarij, Dilma’aarij Djoko Suwito Fakurazi, Shariza Ida Nurwati Muhammad Afif Muthmainah Muthmainah Muthmainah Muthmainah Nanang Wiyono Ratih Puspita Febrinasari Ratih Puspita Febrinasari Selfi Handayani Solikah, Tri Agusti Tri Agusti Sholikah Yudhani, Ratih Dewi