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All Journal Journal Syifa Sciences and Clinical Research (JSSCR)
A. Mu’thi Andy Suryadi
Jurusan Farmasi Fakultas Olahraga dan Kesehatan, Universitas Negeri Gorontalo, Jl. Jenderal Sudirman No. 06 Kota Gorontalo 96128, Indonesia
Chemistry Medicine & Pharmacology

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Standarisasi Mutu Tanaman Herbal Aur-Aur (Commelina longifolia L.) dan Tanaman Bungango (Flueggea virosa Royle) Andi Makkulawu; A. Mu’thi Andy Suryadi; Muhammad Taupik; Mahdalena Sy. Pakaya; Ariani. H Hutuba
Journal Syifa Sciences and Clinical Research Vol 4, No 3 (2022): Volume 4 Edisi 3 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i3.16044

Abstract

In the developing materials for traditional medicines, it is necessary to standardize the quality of plant materials. Tuhus, quality, stability, and safety. This study aims to determine several standardization parameters and determine the flavonoid content of the 70% ethanol fraction of aur-aur leaves (Commelina longifolia L.) and bungango leaves (Flueggea virosa Royle) to ensure that the fractions have quality and measurable parameter values. The fraction was standardized with two parameters, thus specific and non-specific, and flavonoid content test using UV-Vis spectrophotometry method. The results of phytochemical screening, the fraction containing flavonoid compounds is 70% ethanol fraction. Standardization of specific parameters showed the organoleptic results of both aur-aur (Commelina longifolia L.) and bungango (Flueggea virosa Royle) leaf fractions in the form of a semi-solid viscous fraction, black in color, and characteristic odor. The content of water soluble extract and ethanol soluble extract of aur-aur (Commelina longifolia L.) leaf fraction were 22.84%, ethanol soluble extract 25.03%, while the fraction of Bungango (Flueggea virosa Royle) leaf was 30.70%. and 27.31%. Standardization of non-specific parameters showed the results of water content 21.40%, total ash content 8.92%, acid insoluble ash content 0.043%, drying shrinkage 10.48%. The results of non-specific standardization of bungango leaves (Flueggea virosa Royle) showed a moisture content of 14.45%, a total ash content of 9.62%, an acid insoluble ash content of 1.31%, a drying shrinkage of 10.64%. The results for the analysis of the flavonoid content of the 70% ethanol fraction of aur-aur leaves and bungango leaves were carried out at a wavelength of 438.36 nm. The total flavonoid content was calculated by the standard linear equation of quercetin, namely y= 0.0648x + (-0.0232) with a correlation coefficient (r2) = 0.9948 with the total flavonoid content of aur-aur leaf and bungango leaf each of 3.57. % and 9.578%.
Tingkat Pengetahuan Masyarakat Terhadap Tindakan Penggunaan Antibiotik Tanpa Resep Dokter Madania Madania; A. Mu’thi Andy Suryadi; Fika Nuzul Ramadhani; Andi Makkulawu; Dizky Ramadani Putri Papeo
Journal Syifa Sciences and Clinical Research Vol 4, No 3 (2022): Volume 4 Edisi 3 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i3.7141

Abstract

Antibiotics is a subtance that can kill or weaken an organism such as bacteria, parasite, or fungi.  The use of antibiotics always triggers a problem, such as the use of it without any medical prescription. It sometimes happens caused by some factors such as the lack of people’s knowledge concerning the consumption of antibiotics. This research aims at investigating the correlation between the respondent’s characteristics toward knowledge, attitude, and action. Also, it is to investigate the correlation between knowledge and attitude toward the consumption of antibiotics without medical prescription. The research design applies analytical observation with cross sectional approach. The research subjects are 96 respondents selected by purposive sampling technique. The research instrument is questionnaires consisting of questionnaire of knowledge, attitude, and action. The method of data analysis is multiple correlation. Findings reveal that the people’s level of knowledge is still low obtaining 47,7% of score, the people’s attitude is categorized negative (supporting the consumption of antibiotics without medical) obtaining 54,2%, the people’s action categorized not appropriate obtaining 57,3%, there is correlation between education and job toward knowledge, attitude, and action (p0,05), there is no correlation between age and sex toward knowledge, attitude, and action (p0,05), and there is a correlation between knowledge and attitude toward action (p=0,000).
Co-Authors Andi Makkulawu Ariani H. Hutuba Fika Nuzul Ramadhani Madania, Madania Mahdalena Sy Pakaya Muhammad Taupik Papeo, Dizky Ramadani Putri