Article Per Year (5 Year)
p-Index From 2020 - 2025
3.86
P-Index
This Author published in this journals
All Journal Journal Syifa Sciences and Clinical Research (JSSCR) Kumawula: Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Pharmaceutical Education Jurnal Kolaboratif Sains Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Jurnal Farmasi Teknologi Sediaan dan Kosmetika (JFTSK) Journal of Pharmacology and Natural Products
Fika Nuzul Ramadhani
Universitas Negeri Gorontalo
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 27 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 27 Documents
Search

 1   2   3 
Potensi Antioksidan Masker Gel Peel-Off dari Ekstrak Buah Tomat A. Mu’thi Andy Suryadi; Juliyanty Akuba; Fika Nuzul Ramadhani; Ariani H. Hutuba
Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i1.14299

Abstract

Tomatoes are well-known as the source of antioxidants due to the content of lycopene, i.e., a potential free radical inhibitor. Gel peel-off masks are among the chemical products containing antioxidants. The objective of this study is to formulate and examine the antioxidant activity of the gel peel-off mask made of tomato (Solanum Lycopersicum L.) extract using the DPPH method. The first step of the study was extracting tomato fruits by macerating the fruits using alcohol solvents 96%. The obtained thick extract was used as the material of the gel mask; the percentage of the extract comprised 3% (F1), 5% (F2), and 7% (F3), and it used PVA basis 11% and viscolam 3%. According to the result, the gel peel-off masks meet the requirements of physical and storage stability evaluation. The result of the antioxidant test reveals that the IC50 value of the three masks is F1 189.22 µg/mL, F2 89.34 µg/mL, and F3 36.77 µg/mL. Further, the result of T-Test reveals that P-value = 0.019 (α = 0.05), indicating a difference in the result of the antioxidant test of the three formulae in day one (t0) and day 28 (t28).
Studi Rasionalitas Pemakaian Obat Antihipertensi Pada Kasus Pasien Rawat Jalan Teti Sutriati Tuloli; Endah Nurrohwinta Djuwarno; Faramita Hiola; Fika Nuzul Ramadhani; Divia Handayani Mudjidu
Journal Syifa Sciences and Clinical Research Vol 4, No 3 (2022): Volume 4 Edisi 3 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i3.16018

Abstract

Hypertension is a disease that happens when the systolic and diastolic blood pressure is higher than 140/90 mmHg. This study aimed to identify the use of an anti-hypertension drug on outpatients at Kota Timur Community Health Center in Gorontalo, with medical records of hypertension patients from January to June 2021 as the data source. Employing the univariate analysis method, this study obtained patients' data to be recapitulated into the primary table to be descriptively analyzed. The findings in gender frequency revealed that 36 male respondents attained 53.3% of percentage and 81 female respondents attained 46.6% of percentage, while the respondent age frequency that is mostly 46-65 years old numbered 83 patients (71%), 26-45 years old numbered 22 patients (18.80%), and 65 years old numbered 12 patients (10.25%). Based on drug use from January to June 2021, the most consumed drug is Amlodipine, with 70 consumption (60%). Further, based on diseases in other categories from January to June 2021, the highest diagnosis on hypertension patients is 71 times of hypertension (60%), while the systolic and diastolic pressure category from January to June 2021 revealed that the highest blood pressure of the stage 1hypertension patients is 63 times (54%).
Skrining Fitokimia dan Uji Aktivitas Antioksidan Kulit Batang Matoa (Pometia pinnata) Dengan Metode 1,1-Diphenyl-2 picrylhidrazyl (DPPH) Hamsidar Hasan; Nur Ain Thomas; Faramita Hiola; Fika Nuzul Ramadhani; Anggun Sasmita Ibrahim
Indonesian Journal of Pharmaceutical Education Vol 2, No 1 (2022): Januari-April 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i1.10995

Abstract

Pometia pinnata is a plant belonging to the Sapindaceae family that spread in the tropics, including Indonesia, which can be used as antioxidants. It is known to contain flavonoid compounds. Flavonoid is a substance that has antioxidants in capturing free radicals because it contains a hydroxyl group which is a reducer and can be beneficial for hydrogen donors to free radicals. This study aims to determine the chemical content and antioxidant activity of Pometia pinnata skin using 1,1-Diphenyl-2-Picrylhidrazyl (DPPH). Sample extraction was conducted using a multilevel extraction method with n-hexane, chloroform, ethyl acetate, and ethanol as solvents. The results showed that Pometia pinnata skin extract contains Alkaloids, Flavonoids, Saponins, Tannins, Steroids, and Terpenoids. While the value of antioxidant activity showed the IC50 value of n-hexane, chloroform, ethyl acetate, and ethanol extracts are 25, 5, 9, 4 µg/mL. The IC50 value indicates that the antioxidant activity is in an extremely strong category.
Tingkat Pengetahuan Masyarakat Terhadap Tindakan Penggunaan Antibiotik Tanpa Resep Dokter Madania Madania; A. Mu’thi Andy Suryadi; Fika Nuzul Ramadhani; Andi Makkulawu; Dizky Ramadani Putri Papeo
Journal Syifa Sciences and Clinical Research Vol 4, No 3 (2022): Volume 4 Edisi 3 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i3.7141

Abstract

Antibiotics is a subtance that can kill or weaken an organism such as bacteria, parasite, or fungi.  The use of antibiotics always triggers a problem, such as the use of it without any medical prescription. It sometimes happens caused by some factors such as the lack of people’s knowledge concerning the consumption of antibiotics. This research aims at investigating the correlation between the respondent’s characteristics toward knowledge, attitude, and action. Also, it is to investigate the correlation between knowledge and attitude toward the consumption of antibiotics without medical prescription. The research design applies analytical observation with cross sectional approach. The research subjects are 96 respondents selected by purposive sampling technique. The research instrument is questionnaires consisting of questionnaire of knowledge, attitude, and action. The method of data analysis is multiple correlation. Findings reveal that the people’s level of knowledge is still low obtaining 47,7% of score, the people’s attitude is categorized negative (supporting the consumption of antibiotics without medical) obtaining 54,2%, the people’s action categorized not appropriate obtaining 57,3%, there is correlation between education and job toward knowledge, attitude, and action (p0,05), there is no correlation between age and sex toward knowledge, attitude, and action (p0,05), and there is a correlation between knowledge and attitude toward action (p=0,000).
Variasi Konsentrasi Bahan Pengikat Dari Pati Biji Durian (Durio Zibethinus)Terhadap Mutu Fisik Pada Formulasi Tablet Hisap Vitamin C Nur Ain Thomas; Fika Nuzul Ramadhani; Juliyanti Akuba; Ariani H. Hutuba
Journal Syifa Sciences and Clinical Research Vol 4, No 2 (2022): Volume 4 Edisi 2 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i2.4317

Abstract

Starch of durian (Durio Zibethinus) seed is an accessible potential material to be utilized as binding agent in tablet. This study attempts to discover the influence of starch concentrate of durian seed in different percentages, i.e., 20%, 25%, and 30%, as binding agent towards the physical quality (by conducting tests i.e. weight uniformity test, hardness test, friability test, dissolution test, and organoleptic evaluation) towards vitamin C lozenges tablet formulation. Three formulae with different durian seed concentrate variation of F1 (20%), F2 (25%), and F3 (30%) were applied during the formulation of vitamin C lozenges. The result indicates that F2 and F3 formulae fulfilled all the test conducted, while the F1 formula only passed the weight uniformity test, taste response test, and organoleptic test. Based on the results of the study, F3 fulfilled all evaluations carried out, namely F3 4.07 kg hardness test, 0.30% friability test, 443.3 seconds dissolution test. F2 hardness test 3.79 kg, fragility test 0.34% solubility test 402 seconds. F1 hardness test 3.17 kg, fragility test 1.33%, soluble time test, 302.3 seconds. the conclusion obtained from the ANOVA-One way test is that there is a significant disintegration time difference of all formulas and continued by the Post-Hoct test to see the comparison of each formula with a confidence level (95%).
Pencegahan Stunting Melalui 5 Pilar Sanitasi Total Berbasis Lingkungan Di Desa Ulantha Sri Manovita Pateda; Fika Nuzul Ramadhani; Nur Ayun R. Yusuf
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 2, No 1 (2023): Volume 2, Edisi 1, 2023
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (490.084 KB) | DOI: 10.3731/phar.soc.v2i1.18590

Abstract

Stunting atau pendek menjadi topik yang hangat akhirakhir ini, menggeser issue tentang gizi buruk dan obesitas. Stunting merupakan akibat dari malnutrisi kronis yang sudah berlangsung bertahun-tahun. Stunting adalah kondisi gagal tumbuh pada anak balita (bayi di bawah lima tahun) akibat dari kekurangan gizi kronis sehingga anak terlalu pendek untuk usianya. Stunting disebabkan oleh Faktor Multi Dimensi. Salah satu penyebab anak mengalami stunting adalah kurangnya akses ke air bersih dan sanitasi. Lingkungan fisik ini menentukan derajat kesehatan masyarakat. Data menunjukkan bahwa 1 dari 5 rumah tangga masih BAB diruang terbuka, dan 1 dari 3 rumah tangga belum memiliki akses ke air minum bersih. Penanganan stunting dilakukan melalui intervensi spesifik dan intervensi sensitive. Intervensi fisik untuk sanitasi mencegah stunting merupakan bagian dari intervensi sensitive. Sanitasi Total Berbasis Lingkungan (STBL) dicanangkan pemerintah untuk mengurangi angka stunting melalui 5 pilar STBM, yaitu: (1) Cuci tangan menggunakan sabun; (2) Berhenti buang air besar sembarangan; (3) Pengelolaan air minum dan makanan rumah tangga; (4) Pengelolaan limbah cair rumah tangga; (5) Pengelolaan sampah rumah tangga.
Pemberian Edukasi dengan Leaflet Penggunaan Obat Tetes Telinga Fika Nuzul Ramadhani; Nur Rasdianah
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 1, No 1 (2022): Vol 1 Edisi 1 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1052.506 KB) | DOI: 10.3731/phar.soc.v1i1.13959

Abstract

Pemberian edukasi mengenai cara penggunaan obat sediaan khusus seperti tetes telinga sangat penting karena terdapat titik kritis pada sediaan tetes telinga terutama pada cara penetesan. Pemberian informasi yang kurang lengkap dan jelas mengenai cara penggunaan obat akan mengakibatkan terapi kurang maksimal sehingga obat tidak akan mencapai efek terapi yang dinginkan. Kegiatan pengabdian kepada masyarakat ini bertujuan agar dapat meningkatkan pengetahuan masyarakat mengenai cara penggunaan obat tetes telinga yang benar. Pengabdian ini dilakukan dengan cara memberikan informasi melalui pemberian leaflet dan menjelaskan langsung pada masyarakat. Pemberian edukasi cara pemberian obat sediaan tetes telinga pada masyarakat mendapatkan respon yang baik karena sebagian besar masyarakat kurang mengetahui tentang cara penggunaan yang benar. Pengabdian ini memberikan manfaat yang besar bagi masyarakat desa agar mendapatkan efek terapi obat yang maksimal dengan cara penggunaan sediaan yang benar.
Upaya Peningkatan Status Gizi Anak sebagai Pencegahan Stunting di Desa Mongiilo Utara Bone Bolango Fika Nuzul Ramadhani; Endah Nurrohwinta Djuwarno; Nur Ayun R Yusuf
Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Vol 1, No 3 (2022): Vol 1 Edisi 3 (2022)
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (771.895 KB) | DOI: 10.3731/phar.soc.v1i3.18286

Abstract

Nutritional problem is one of the causes of increasing stunting incidence in an area which has a long term impact for children. Stunting in children is characterized by a child's height that is below average or also known as failure to thrive. Stunting in children can cause developmental delays in the brain so that long-term effects can cause mental retardation, low learning ability and the risk of chronic disease. Innovation in food sector by making biscuits with nuts and vegetable composition is very important to increase children's interest for consuming vegetables that are rich in nutrients for prevent stunting. This community service activity aims to prevent stunting in the people of North Mongiilo Village by providing information processing of biscuits with many nutrient. This service is carried out by providing information through video tutorials on making biscuits and explaining directly to the public about the benefits and nutritional content of the ingredients used in making biscuits. Providing information on how to make biscuits to the community received a good response because most people did not know about innovations in making biscuits made from nuts and vegetables that children could like. This service provides great benefits for the village community in order to gain knowledge about the benefits and important nutritional content of vegetables and improve the community's economy with innovations in production of biscuits made from nuts and vegetables.
Hubungan Kepatuhan Konsumsi Kalsium Karbonat terhadap Kadar Fosfat Pasien Gagal Ginjal dengan Hemodialisis Fika Nuzul Ramadhani
Journal Syifa Sciences and Clinical Research Vol 5, No 1 (2023): Volume 5 Edisi 1 2023
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v5i1.19121

Abstract

Non-adherence to renal failure treatment increases the risk of disease complications, such as metabolic disorders of calcium and phosphate. Education is one of way to increase medication adherence. Education is one way to increase patient compliance in therapy. One way of conducting education is by giving leaflets. This study aims to determine the correlation between compliance with consumption of calcium carbonate and phosphate levels in patients with kidney failure on hemodialysis. This research were experimental and prospective study at PKU Muhammadiyah General Hospital, Yogyakarta City for 4 weeks using the one-group pretest posttest design to test patients' phosphate levels pre and post administation of leaflets increase adherence. Sample consisted of 70 kidney disease patients with hemodialysis were divided into 2 groups, each consisting of 35 patients. The intervention group were given education leaflets and checking phosphate levels, while the control group were not given leaflets. Data were obtained from medical records, questionnaire instruments and phosphate laboratory data. The level of patient adherence in taking calcium carbonate medication assessed by MMAS questionnaire and phosphate levels of patients. Data were analysis using the Wilcoxon test and Spearman test.The results of the analysis between adherence and phosphate levels showed no relationship between adherence and phosphate levels p=0.591 (p0.05). Overall, it can be concluded that there is no correlation between adherence to calcium carbonate consumption and phosphate levels
Analisis Kualitatif Metabolit Sekunder dan Aktivitas Antioksidan Jamur Endofit Cangkang Bulu Babi (Diadema setosum) Widy Susanti Abdulkadir; Mahdalena Sy. Pakaya; Fika Nuzul Ramadhani; Wiwit Zuriyati Uno; Arona Salama
Indonesian Journal of Pharmaceutical Education Vol 3, No 2 (2023): Mei-Agustus 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i2.18019

Abstract

Endophytic fungi are fungi that live in plant tissues for a certain period and can form colonies in the host's tissues without endangering the host itself. In addition to plants, endophytic fungi are also found in marine biota. Endophytic fungi that live in the internal organs or tissues of marine biota, whether in the form of mold or yeast, can transform the nutrients they obtain from their host animals into metabolite compounds which will then be transferred back to the host organs so that they have the same metabolites as their hosts. This study aimed to analyze and test the antioxidant activity of the secondary metabolites of sea urchins in the Tomini Bay area. The method used from the beginning of the research was endophytic microbial fermentation, production of secondary metabolites, and partitioning of endophytic microbial isolates, namely liquid-liquid; the method used to test antioxidant activity was qualitative using TLC plates, DPPH UV-Vis spectrophotometer method, color reagent, and thin layer chromatography. Two isolates of endophytic fungi were obtained, namely (JBB1, JBB2). The isolate that was active as an antioxidant was JBB2 from sea urchins in the Tomini Bay area with an ICso 50-100 ppm, which was in the strong category. Meanwhile, JBB2 isolate was carried out at a wavelength of 517 nm with a value absorbance of 0,707 A. In accordance with the value of the linear equation, it obtained y = 0,092x+36,95 and an R2 value = 0,945 that the ethyl acetate extract in JBB2 had a moderate ICs of 87.43 µg/mL. Meanwhile, the qualitative test of secondary metabolites using thin layer chromatography with n-hexane eluent: ethyl acetate (8:2) ethyl acetate extract contained alkaloid and terpenoid compounds.
Co-Authors A. Mu’thi Andy Suryadi A. Mu’thi Andy Suryadi Abdullah, Rahayu Anatasya Putri Akuba, Juliyanti Andi Makkulawu Andy Suryadi, A. Mu'thi Anggun Sasmita Ibrahim Ariani H. Hutuba Ariani H. Hutuba Arona Salama Asral Kelvin Sahrain Bakari, Mohamad Fadly Divia Handayani Mudjidu Dizky Ramadani Putri Papeo Dr. Apt. Hamsidar Hasan S.Si.,M.Si Endah Nurrohwinta Djuwarno Halada, Ichlasul Oktofandi Hamsidar Hasan Hamsidar Hasan Hendrawan Dwikarunia Datukramat Hiola, Faramita Julianty Akuba Khairun nisha Samsi Latif, Multiani S. Madania, Madania Mahdalena Sy Pakaya mahdalena sy. pakaya Makkulawu, Andi Maku, Diva Julyar Cahyani Manno, Mohamad Reski Mohamad Adam Mustapa Mohamad Aprianto Paneo Multiani S. Latif Naharil Mumtazah Nur Ain Thomas Nur Ain Thomas Nur Ayun R Yusuf Nur Ayun R Yusuf Nur Rasdianah Oktaviani Kahar Pakaya, Susanti Papeo, Dizky Ramadani Putri Rifka Anggraini Anggai Robert Tungadi Safira Mahadewi Mamu Selvi Marcellia Sitty Rahma Hutami Kongkolu Sri Manovita Pateda Sukmaty Damiti Sukmawati Damiti Teti Sutriyati Tuloli Umi Yuminarti Umi Yuminarti Widy Susanti Abdulkadir Widy Susanti Abdulkadir Wiwit Zuriati Uno