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All Journal Jurnal Biogenerasi Formosa Journal of Applied Sciences (FJAS)
Fajrin Noviyanto
STIKES Salsabila Serang
Control & Systems Engineering Decision Sciences, Operations Research & Management Education Engineering Languange, Linguistic, Communication & Media Social Sciences Other

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Formulasi dan Evaluasi Sediaan Hand Body Lotion Ekstrak Etanol Daun Semangka (Citrullus lanatus) sebagai Antioksidan Fakihah Wardatun Aljanah; Swastika Oktavia; Fajrin Noviyanto
Formosa Journal of Applied Sciences Vol. 1 No. 5 (2022): October 2022
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjas.v1i5.1483

Abstract

Daun semangka (C. lanatus) mengandung flavonoid, fenolik, tanin, triterpen, sterol dan alkaloid serta memiliki aktivitas antioksidan dengan nilai IC50 sebesar 37,12 µg/mL. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan ekstrak etanol daun semangka (C. lanatus) dan formulasi sediaan hand body lotion ekstrak etanol daun semangka. Jenis penelitian yang dilakukan adalah eksperimental laboratorium secara in vitro. Prosedur penelitian yaitu determinasi, pembuatan ekstrak daun semangka, skrining fitokimia, pembuatan hand body lotion ekstrak daun semangka konsentrasi 3, 5 dan 7%, evaluasi sediaan dan pengujian aktivitas antioksidan dengan metode DPPH. Hasil penelitian menunjukkan bahwa ekstrak etanol daun semangka (C. lanatus) memiliki efek antioksidan dengan nilai IC50 sebesar 56,44 ppm (kategori antioksidan kuat). Ekstrak etanol daun semangka (C.  lanatus) dapat diformulasi menjadi sediaan hand body lotion yang memenuhi persyaratan organoleptik, homogenitas, pH, viskositas, daya sebar, daya lekat dengan tipe emulsi M/A. Lotion ekstrak etanol daun semangka (C. lanatus) di semua konsentrasi yang diujikan (3, 5, 7%) tidak memiliki aktivitas antioksidan dengan nilai IC50 berturut-turut sebesar 3981,48, 842,19 dan  926,71 ppm
Uji Aktivitas Antioksidan dari Formulasi Sabun Mandi Cair Ekstrak Etanol Biji Kopi Robusta (Coffea canephora) Achmad Saehu; Nani Suryani; Fajrin Noviyanto
Jurnal Biogenerasi Vol. 7 No. 2 (2022): Jurnal Biogenerasi Vol 7 Nomor 2 tahun 2022
Publisher : Universitas Cokroaminoto Palopo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30605/biogenerasi.v7i2.1978

Abstract

Soap is one of cosmetic products whose purpose is to cleanse the body of soiled. Several cosmetic products were added antioxidant to protect skin from free radical that caused skin damage such as aging. Robusta coffee beans (Coffea canephora) contain bioactive phenolic compounds such as fenolic acid, chlorogenic acid and caffeic acid that have antioxidant, also have an aromatic distinctive odor. Any research mention that antioxidant activities of unroasted robusta coffee beans have value of IC50 0,131 (mg/ml), while other research mention that robusta coffe bean have value of IC50 140,24 ppm and classified as moderate antioxidant according to Blois criteria. The benefits of the coffee can be used as an active ingredient in liquid soap. The aim of this study to determine the formula of ethanol extract Robusta (Coffea canephora) liquid soap and antioxidant activities test. Liquid soap is made in four formulations with variation of coffee extract 0%; 0,014%; 0,14%; and 1,4 % and with test criteria physical properties, pH and free alkali test compared with the standard quality of liquid soap SNI 06-4085. Antioxidant activities test were used DPPH method with spectrophotometry uv-vis with 515 nm wave length. The absorbance of DPPH solutions before and after addition the sample was calculated as percent (%) of inhibition. Then the percent of inhibition value is entered into linear regression equation until the IC50 value is obtained. The result of the phytochemical test of coffee bean exstract contain alkaloid compounds which are antioxidants. Physical test, pH and free alkali did not meet all SNI quality standards, as well as antioxidant acticity test which gave IC50 values above 200, which means they have no antioxidant acticity. Therefore, in further research, it is necessary to optimized the formulation
Co-Authors Achmad Saehu Fakihah Wardatun Aljanah Nani Suryani Swastika Oktavia