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All Journal INDONESIAN JOURNAL OF LEGAL AND FORENSIC SCIENCES Jurnal Farmasi Udayana JPSCR : Journal of Pharmaceutical Science and Clinical Research JOURNAL SCIENTIFIC OF MANDALIKA (JSM) JAFP (Jurnal Akademi Farmasi Prayoga) Innovative: Journal Of Social Science Research Prosiding Workshop dan Seminar Nasional Farmasi (WSNF) JURNAL FARMASI DAN KESEHATAN INDONESIA Journal of Public Health and Pharmacy
Pande Made Nova Armita Sari, Pande Made Nova
Program Studi Farmasi, Fakultas Matematika Dan Ilmu Pengetahuan Alam, Universitas Udayana
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Public Health Other

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Journal : INDONESIAN JOURNAL OF LEGAL AND FORENSIC SCIENCES

 1 
BLIND TEST GOLONGAN SENYAWA PSIKOTROPIKA DALAM SAMPEL URIN Gusti Ayu Kopang Maharani; Putu Ayu Rismayani; Ni Nyoman Adhi Satvika Devi; Ni Putu Metha Pradnyandari Putri Winarni; Pande Made Nova Armita Sari
Indonesian Journal of Legal and Forensic Sciences (IJLFS) Vol 9 No 2 (2019): Indonesian Journal of Legal and Forensic Sciences
Publisher : Penerbit, sejak 2012 : Asosiasi Ilmu Forensik Indonesia dan UPT Lab. Forensik Sain dan Kriminilogi - Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/IJLFS.2019.v09.i02.p05

Abstract

Cases of psychotropic abuse have occurred in Indonesia. Drug abuse or detrimental use is the use of psychotropic without medical supervision. The case of drug abuse is a case that requires forensic toxicology examination. Forensic toxicology examination consists of the stages of screening tests, confirmation tests, and interpretation of results. This study aims to determine the psychotropic compounds contained in urine samples. The screening test method used is the immunoassay technique using a strip test, the results obtained that urine samples show positive results on the barbiturate group test strips. Confirmation test method is done by TLC-Spectrophotodensitometry method, the results obtained that the barbiturate class compounds contained in the sample are phenobarbital compounds. Furthermore, a determination test was performed and the results were obtained that the levels of phenobarbital in urine in a 4 µl drop volume with replication 3 times were 22.97 ng / µl, 34.66 ng / µl, and 22.42 ng / µl.
KASUS KEMATIAN AKIBAT DICHLORVOS DAN PHENTHOAT Putu Nandya Nandita; Ni Made Widi Astuti; IMA Gelgel Wirasuta; Pande Made Nova Armita Sari
Indonesian Journal of Legal and Forensic Sciences (IJLFS) Vol 9 No 1 (2019): Indonesian Journal Of Legal And Forensic Sciences
Publisher : Penerbit, sejak 2012 : Asosiasi Ilmu Forensik Indonesia dan UPT Lab. Forensik Sain dan Kriminilogi - Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/IJLFS.2019.v09.i01.p05

Abstract

Dichlorvos and phenthoat are organophosphate group pesticides which have toxic effects on humans and can cause fatal deaths. Suicide cases using organophosphate pesticides (dichlorvos and phenthoat) are one of the postmortem toxicology analysis studies. As a forensic toxicologist, competency is needed to be able to handle suicide deaths that are thought to be caused by dichlorvos and phenthoat. Handling suicides due to dichlorvos and phenthoate is done from sample preparation, screening tests, assurance tests, determination, and data interpretation. Forensic toxicology analysis in the case showed that high concentrations of dichlorvos and phenthoate were found to have toxic effects on the victim's body. Based on the toxicological analysis, it can be concluded that it is true that the victim died from organophosphate poisoning (dichlorvos and phenthoat).
PENGEMBANGAN METODE IDENTIFIKASI DAN PENETAPAN KADAR RODAMIN B PADA SAMPEL JAJANAN TRADISIONAL DENGAN METODE KROMATOGRAFI LAPIS TIPIS-SPEKTROFOTODENSITOMETRI Pande Made Nova Armita Sari
Indonesian Journal of Legal and Forensic Sciences (IJLFS) Vol 10 No 2 (2020): Indonesian Journal of Legal and Forensic Sciences
Publisher : Penerbit, sejak 2012 : Asosiasi Ilmu Forensik Indonesia dan UPT Lab. Forensik Sain dan Kriminilogi - Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/IJLFS.2020.v10.i02.p06

Abstract

ABSTRAK Zat pewarna sintetis digunakan karena komposisinya lebih stabil dan relatif lebih murah. Contoh pewarna sintetis adalah sunset yellow FCF yang memberi warna oranye, karmoisin yang memberikan warna merah, serta Tartrazine untuk warna kuning. Zat warna yang dilarang digunakan dalam pangan tercantum dalam Peraturan Menteri Kesehatan RI Nomor 239/MenKes/Per/V/85 mengenai Zat Warna Tertentu yang Dinyatakan sebagai Bahan Berbahaya. Salah satu zat warna yang dinyatakan bahan berbahaya adalah rodamin B. Rodamin B masih banyak ditemukan pada produk kosmetik dan juga berbagai komoditas pangan. Paparan jangka panjang dengan rodamin B dapat menyebabkan kanker dan resiko cacat kelahiran. Oleh karena itu akan dikembangkan metode analisis kromatografi lapis tipis (KLT) untuk identifikasi dan penetapan kadar rodamin B di produk jajanan tradisional. Dikembangkan enam fase gerak untuk memisahkan senyawa rodamin B dari pewarna lain. Dari hasil yang diperoleh,fase gerak 6 (Etanol:air:asam asetat:dietilamin (95:5:5:1) adalah fase gerak yang paling mampu memisahkan beberapa pewarna sekaligus. Uji kualitatif dengan KLT-spektrofotodensitometri didapatkan bahwa sampel yang positif mengandung rodamin B adalah sampel KM3 dan KM 5. Hal ini disimpulkan drai Rf dan spectrum yang sama dengan rodamin, Yaitu Rf 0,72. Persamaan garis regresi yang diperoleh adalah y = 564,534 + 1,799x dan r = 0,9946 dengan rentang linieritas 200-1500 ppm. Pada penetapan kadar sampel yang mengandung rodamin B, yaitu pada sampel KM3 dan KM B, secara berturut-turut kadar yang diperoleh adalah 0,676 mg/1 gram sampel dan 2,751 mg/1 gram sampel
UJI SKRINING DAN DETERMINASI KODEIN DALAM SAMPEL URIN I Putu Priyasana; Gusti Ayu Dinda Mayagita; Vallina Rahmadinha; Kristina Megi Limba; Pande Made Nova Armitasari
Indonesian Journal of Legal and Forensic Sciences (IJLFS) Vol 10 No 1 (2020): Indonesian Journal of Legal and Forensic Sciences
Publisher : Penerbit, sejak 2012 : Asosiasi Ilmu Forensik Indonesia dan UPT Lab. Forensik Sain dan Kriminilogi - Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/IJLFS.2020.v10.i01.p04

Abstract

Opiates are a group of narcotics that are often abused. Forensic experts play crucial roles in handling this. The screening test results that the sample containing opiate compounds. Confirmation testing is carrie out by using TE and TAE mobile phase systems. The error window values ??obtained in the TE and TAE systems are 10 and 8. Data collection of compounds in the range of hRfc 16.09 to 36.09 in the TE system obtained two compounds, Morphine and Codeine). And in the range of hRfc 25.1-9.1 also found Morphine and Codein compounds. The results of the correlation spectrum of the sample and spectrum in the library showed a correlation value of 0.99079 (TE system) and 0.99477 (TAE system) to the codeine compound. Determination testing is carried out using the TE mobile phase. This test results obtained that the concentration of codeine compounds is 20.88 ng / µL. These results indicate that the sample contains codeine in the lethal dose range.
KASUS AGITASI AKIBAT PEMAKAIAN MEPHEDRONE Ni Made Widi Astuti; Dewa Ayu Sri Kusuma Dewi; Pande Made Nova Armita Sari; IMA Gelgel Wirasuta
Indonesian Journal of Legal and Forensic Sciences (IJLFS) Vol 9 No 1 (2019): Indonesian Journal Of Legal And Forensic Sciences
Publisher : Penerbit, sejak 2012 : Asosiasi Ilmu Forensik Indonesia dan UPT Lab. Forensik Sain dan Kriminilogi - Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/IJLFS.2019.v09.i01.p06

Abstract

Mephedrone or 4-Methylmethcathinone is one type of NPS (New Psychoactive Substance) which is included in the katinon derivative. Mephedrone has been banned in Indonesia and in other countries such as the Netherlands. Mephedrone is used as a recrerational drug that can increase enthusiasm for its users. Misuse of mephedrone can cause toxicity to death for its users. In reviewing this article we will summarize the cases of mephedrone abuse in Indonesia, the pathway for mephedrone synthesis, the pharmacological, pharmacokinetic and pharmacodynamic effects of mephedrone and forensic toxicology analysis on cases of misuse of mephedrone compounds.
UJI SKRINING DAN DETERMINASI KODEIN DENGAN TLC SPEKTROFOTODENSITOMETRI Pande Made Nova Armita Sari; Ni Putu Eka Leliqia
Indonesian Journal of Legal and Forensic Sciences (IJLFS) Vol 3 (2013): Indonesian Journal of Legal and Forensic Sciences
Publisher : Penerbit, sejak 2012 : Asosiasi Ilmu Forensik Indonesia dan UPT Lab. Forensik Sain dan Kriminilogi - Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

A current research of screening and determination of codeine using Al-TLC Spectrophotodensitometry has been carried out. The separation was performed using TAEA mobile phase. Screening and confirmation were investigated by comparing hRfc of the analyte and hRfc those on data library. Combination hRfc vs correlation also been used as confirmation method, which can be enhanced by spectrum shift reaction using HCl 10% and KOH 0,1 M. The validation parameters were precission, linierity, limit of detection and quantitation (LOD & LOQ) and recovery.   TAEA mobile phase performed a good separation among morphine, codeine, caffeine, papaverine and bromhexine standards, which gave Rs value > 1. Test of linierity using regression gave correlation value > 0,99 . LOD and LOQ of Al-TLC were 137.85 ng and 459.63 ng. The recovery of codeine in human plasma using isopropanol as the precipitating agent was 77.1% ± 4.9 (6.5%).
Co-Authors A.A. Bagus Yoga Saputra Desak Nyoman Desy Irayanti Dewa Ayu Sri Kusuma Dewi Dyah Kanya Wati Fajaryani, Putu Ayu Putri Gusti Ayu Dinda Mayagita Gusti Ayu Kopang Maharani I Gusti Ayu Rosa Mirah Firdayeni I Ketut Gede Gilang Gama Harta I Made Agus Gelgel Wirasuta I Putu Priyasana Jonathan Setiawan Jonathan Setiawan Komang Tri Wahyu Widiantari Kristina Megi Limba Maha Dewi, Ni Kadek Santi Natalia Kote, Jessica Christy Ni Kadek Warditiani Ni Made Ary Sarasmita Ni Made Widi Astuti Ni Made Widiastuti Ni Nyoman Adhi Satvika Devi Ni Putu Eka Leliqia Ni Putu Indah Widyantari Ni Putu Indah Widyantari Ni Putu Indah Widyantari Ni Putu Linda Laksmiani Ni Putu Metha Pradnyandari Putri Winarni Putu Ayu Rismayani Putu Indah Budi Apsari Putu Nandya Nandita Rhinard Valery Goethe Randang Vallina Rahmadinha Waskito, Andreas Gangsar Bayu