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Toksisitas Oral Akut Arthrospira maxima dan Chlorella vulgaris Isolat Glagah Pada Tikus (Rattus norvegicus Berkenhout, 1769) Galur Wistar Laksmindra Fitria; Tika Candra Dewi; Kholidatus Silmi; Mulyati Mulyati; Rahadian Yudo Hartantyo; Slamet Widiyanto; Eko Agus Suyono
Al-Kauniyah: Jurnal Biologi Vol 15, No 2 (2022): AL-KAUNIYAH JURNAL BIOLOGI
Publisher : Department of Biology, Faculty of Science and Technology, Syarif Hidayatullah State Islami

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/kauniyah.v15i2.18716

Abstract

AbstrakArthrospira (Spirulina) dan Chlorella adalah mikroalga yang telah dikenal bermanfaat bagi kesehatan sehingga banyak dikembangkan sebagai produk suplemen makanan. Penelitian ini bertujuan untuk mempelajari tingkat ketoksikan dan keamanan mengkonsumsi A. maxima dan C. vulgaris yang diisolasi dari perairan Pantai Glagah di Provinsi D.I. Yogyakarta menggunakan tikus Wistar sebagai model praklinis. Studi toksisitas merupakan langkah awal sebelum dilakukan eksplorasi potensi, pemanfaatan, dan pengolahan kedua mikroalga ini sebagai produk suplemen kesehatan. Prosedur uji toksisitas mengikuti Guideline OECD No. 420. Parameter yang diamati meliputi berat badan, profil hematologis, evaluasi fungsi hati (aktivitas ALT dan kadar bilirubin), serta fungsi ginjal (kadar kreatinin dan asam urat). Berdasarkan hasil, dapat disimpulkan bahwa pemberian per oral A. maxima dan C. vulgaris hingga dosis 5.000 mg/kg bb tidak menunjukkan tanda-tanda ketoksikan, ditunjukkan dengan nilai untuk sebagian besar variabel yang berada dalam kisaran normal. Fluktuasi nilai yang terjadi merupakan wujud dinamika fisiologis normal. Dalam penelitian ini kami mendapat temuan bahwa C. vulgaris menunjukkan potensi sebagai antianemia. Oleh karena studi toksisitas ini adalah dosis tunggal dan terbatas untuk periode akut, maka perlu dilanjutkan dengan studi toksisitas dosis berulang dan periode yang lebih panjang, selain untuk mempelajari ketoksikan dan keamanan juga untuk menggali potensinya.AbstractArthrospira (Spirulina) and Chlorella are microalgae that possess benefits for health, therefore they are Arthrospira (Spirulina) and Chlorella are microalgae that possess benefits for health, therefore they are developed as food supplement products. This study aimed to determine the toxicity and the safety of consuming A. maxima and C. vulgaris isolated from Glagah coastal water in D.I. Yogyakarta Province using Wistar rats as preclinical model. Toxicity study is the first step before exploring the potential, utilization and processing of these microalgae as health supplement products. Toxicity test procedure was performed following OECD Guideline No. 420. Parameters observed included: body weight, hematological profile, and evaluation of liver function (ALT activity and bilirubin level) and renal function (creatinine and uric acid levels). Based on the results, it is concluded that oral administration of A. maxima and C. vulgaris up to dose of 5,000 mg/kg bw demonstrated no signs of toxicity, indicated by values for most of variables were within normal range. Fluctuation in values were manifestation of normal physiological dynamic. In this study, we found that C. vulgaris could be an antianemia potential. Since this toxicity study was a single-dose and limited to acute period, it is suggested to continue with repeated-dose toxicity studies with longer periods to examine the toxicity and the safety of both species besides exploring their potential.
PENDAMPINGAN BANK SAMPAH SIMPATIK PROJECT MELALUI PENINGKATAN PRODUKTIVITAS DAN PEMASARAN ONLINE DI NAGORI SAIT BUTTU SARIBU KECAMATAN PAMATANG SIDAMANIK Tioner Purba; Elfina Okto Posmaida Damanik; Rolando Sihombing; Eko Agus Suyono; Irkham Widiyono; Djarot Heru Santosa; Jhonson Allen Marbun; Corry Corry
Jurnal Abdimas Bina Bangsa Vol. 4 No. 1 (2023): Jurnal Abdimas Bina Bangsa
Publisher : LPPM Universitas Bina Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46306/jabb.v4i1.402

Abstract

Nagori Sait Buttu is one of the tourist villages in Simalungun Regency, which offers natural beauty and agro-tourism. The problem faced in developing tourism in Sait buttu is waste management. The Simpatik Project Garbage Bank has been established for a long time, but its activities are only collecting waste and selling it. Through this community service, the community is trained to process the collected waste, namely organic waste and inorganic waste. Organic waste is processed into several products such as food and compost, while inorganic waste is processed into various crafts. Products are marketed online and offline. Communities are trained to market their products online by opening a shop on the Shopee application. Financial bookkeeping training was also carried out with the Android cashbook application. Currently, the Sympathetic Project Waste Bank already has various processed waste products that are marketed through Shopee and is able to record finances with the Android cashbook application. Through this service, the community through a sympathetic waste bank benefits by increasing income. Through the activities of the Sympathetic Waste Bank project, the environment is getting cleaner
Community Empowerment for Tidal Inundation Early Warning System in West Aceh Regency Indonesia Rita Oktavia; Dian Kristanti; Nursiah Nursiah; Eko Agus Suyono; Wisnu Nurcahyo; Adhy Kurniawan; Baban Muliadi; Nuzullah Nuzullah; Arli Irdawan; Juwita Juwita; Betriza Betriza
Vokatek: Jurnal Pengabdian Masyarakat Volume 4: Issue 1 (April 2026)
Publisher : Sakura Digital Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61255/vokatekjpm.v4i1.1394

Abstract

Tidal inundation recurs at least twice annually in West Aceh Regency, yet Pasar Aceh Village previously had no Early Warning System (EWS), leaving residents unprepared for recurring flood damage. This community service program, conducted from August to November 2025 with 20 participants, implemented an integrated EWS through four activities: disaster mitigation socialization, EWS training, device installation, and simulation exercises. The program produced an EWS device, a disaster mitigation module, a web-based monitoring system, and a siren alert system. Community competence was evaluated using pre-test and post-test assessments, showing a significant increase in mean scores from 39.7 to 92.0 (a gain of 52.3 points). The installed EWS successfully delivered early warnings prior to flood events, strengthening community coordination and village disaster readiness while improving residents' sense of security in daily activities. These findings confirm that a technology-based community empowerment approach effectively enhances local resilience to tidal inundation, offering a replicable model for similar coastal disaster-prone areas.
Peran Satgas Pengolahan Sampah di Pantai Suak Baru Simeulue dalam Pemanfaatan Kompos dari Daun dan Ranting untuk Produktivitas Pertanian Herri Darsan; Eko Agus Suyono; Raden Wisnu Nurcahyo; Adhy Kurniawan; Yuliatul Muslimah; Rudi Hermi; Muhammad Haikal; Muhammad Irja; Nuzul Baroqah
Jurnal Pengabdian Masyarakat: Darma Bakti Teuku Umar Vol 6, No 2 (2024): Juli-Desember
Publisher : Universitas Teuku Umar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35308/baktiku.v6i2.10799

Abstract

Suak Baru Village in Simeulue Regency, Aceh, faces challenges in waste management, particularly in the tourist area of Suak Baru Beach. This situation is exacerbated by the lack of adequate waste management facilities, leading to environmental pollution that threatens public health and the area's attractiveness to tourists. The design of this community service program aims to increase the community's preparedness for the adoption of environmentally friendly waste management technologies, specifically composting and plastic recycling methods. The activities include socialization, training, technology implementation, and program sustainability evaluation. The program's results show a significant improvement in the community’s understanding of effective waste management. The use of organic and plastic shredding technology successfully reduced waste volume and created economic value through recycled products. It is hoped that government support and active community participation will ensure the sustainability of this program for a cleaner, healthier environment and improved local economic welfare.