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Evaluasi Penggunaan Obat Antituberkulosis (OAT) Pada Pasien Tuberkulosis Paru Di Puskesmas Kalikajar I Periode 2019 Fairuzelsa, Ulfia Rifda; Dewi, Pramitha Esha Nirmala
Proceeding Universitas Muhammadiyah Yogyakarta Graduate Conference Vol. 1 No. 1 (2020): Armoring the Youth to Contribute to the SDGs
Publisher : Universitas Muhammadiyah Yogyakarta

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Abstract

Tuberkulosis paru merupakan penyakit menular yang disebabkan oleh bakteri Mycobacterium tuberculosis. Prevalensi di Indonesia pada tahun 2017 sebanyak 420.994 kasus TB, dan merupakan jumlah kasus terbanyak kedua di dunia setelah India. Apabila angka kasus tuberkulosis paru semakin banyak, maka penggunaan obat antituberkulosis juga akan semakin meningkat, sehingga pengobatan yang diberikan harus rasional. Jika pengobatan yang diberikan tidak rasional maka akan berdampak pada kejadian resistensi obat dan kekambuhan penyakit TB. Penelitian ini bertujuan untuk mengetahui profil pelaksanaan terapi OAT dan evaluasi ketepatan penggunaan obat antituberkulosis pada pasien TB paru berdasarkan Pedoman Penanggulangan Tuberkulosis Tahun 2016. Penelitian ini merupakan penelitian observasional, dengan desain cross sectional. Pengambilan data dilakukan secara retrospektif dengan mengambil data rekam medis pasien TB paru yang terdiagnosis dan mendapatkan obat antituberkulosis di Puskesmas Kalikajar I periode Januari-Desember 2019. Metode pengambilan data secara total sampling. Jumlah sampel yang diambil sebanyak 32 pasien yang memenuhi kriteria inklusi. Hasil penelitian penggunaan obat antituberkulosis pada pasien TB paru di Puskesmas Kalikajar I menunjukkan bahwa sebesar 100% pasien menggunakan OAT KDT (Kombinasi Dosis Tetap), yang terdiri dari penggunaan regimen kategori I sebesar 81%, dan kategori anak sebesar 19%. Hasil evaluasi ketepatan OAT pasien TB paru menunjukkan 100% tepat indikasi, 100% tepat pemilihan obat, dan 100% tepat pasien. Analisis selanjutnya menunjukkan sebesar 84% tepat dosis, sedangkan 69% tepat lama pemberian. Secara keseluruhan terdapat 62,5% pasien TB paru yang mendapatkan OAT secara tepat.
Identifikasi Pengaruh Pengetahuan Penggunaan Skincare Wajah Terhadap Kejadian Akne Vulgaris pada Mahasiswi Kesehatan Universitas Muhammadiyah Yogyakarta Saputri, Alifah Kharisma; Dewi, Pramitha ESha Nirmala
Proceeding Universitas Muhammadiyah Yogyakarta Graduate Conference Vol. 1 No. 1 (2020): Armoring the Youth to Contribute to the SDGs
Publisher : Universitas Muhammadiyah Yogyakarta

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Abstract

Jerawat atau AV merupakan penyakit multifaktorial yang salah satu pemicunya adalah kesalahan dalam penggunaan skincare wajah yang dapat terjadi apabila tidak diimbangi dengan pengetahuan yang cukup. Tujuan penelitian ini untuk mengetahui hubungan antara tingkat pengetahuan dengan kejadian AV pada penggunaan skincare wajah dan mengetahui faktor apa saja yang mempengaruhi hubungan tersebut. Penelitian ini dilakukan menggunakan desain penelitian obeservasional dengan rancangan cross sectional dan bersifat retrospektif pada Mahasiswi FKIK UMY angkatan 2019 serta data berupa data primer yang diambil dengan kuesioner dan assessment tools. Sampel diambil berdasarkan metode purposive sampling dan rumus Slovin. Sehingga, didapatkan 199 responden sebagai sampel dari 235 total responden. Pada penelitian ini didapatkan hubungan yang bermakna (sig =0,037) antara tingkat pengetahuan dengan kejadian AV pada penggunaan skincare wajah. Hasil menunjukkan, faktor jenis kulit berminyak (sig = 0,041) dan kemampuan mengidentifikasi jenis kulit yang dimiliki (sig = 0,000) mempengaruhi hubungan tersebut. Didapatkan kejadian AV tersebut pada sejumlah responden, meskipun responden bertingkat pengetahuan baik dengan jenis kulittidak berminyak. Dimana, hal ini juga didapatkan pada sejumlah responden bertingkat pengetahuan baik dengan kemampuan mengidentifikasi jenis kulit yang dimiliki.
Statin prescribing pattern and the outcomes for acute coronary syndrome as primary and secondary prevention: a comprehensive review Dewi, Pramitha Esha Nirmala; Chairani, Farahdina; Himawan, Wahyu
JURNAL ILMU KEFARMASIAN INDONESIA Vol 23 No 1 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i1.1604

Abstract

Cardiovascular disease is the highest rate of total burden non-communicable disease worldwide in these 5 recent years. Reducing the LDL-c level is closely related to reducing the risk of cardiovascular events recurrences among Acute Coronary Syndrome (ACS) patients. This study aims to explore the statin prescribing pattern among the ACS population and population at risk of ACS and to sum up the reported clinical outcomes, cost-effectiveness, or quality of life-related to statin utilization. The literature searching was conducted by using PubMed and Scopus databases from January 2020 to December 2021. Ten eligible studies were included, examining outcomes such as Major Adverse Cardiovascular Events (MACE), quality of life, and cost-effectiveness. Atorvastatin emerged as the most frequently prescribed statin for both primary and secondary prevention. In high-risk ACS populations, the delayed or underutilization of high-intensity statins led to suboptimal cardiovascular outcomes. Conversely, early administration, particularly within 48 hours post-event or post-PCI, significantly reduced MACE. Importantly, low to moderate intensity statin regimens showed cost-effectiveness primarily among low-risk ACS groups only when treatment was fully subsidized. In settings without government coverage, statin inaccessibility may affect the increased of recurrent events and elevated healthcare costs. The strategic use of statins—especially timely initiation and risk-based intensity selection—offers measurable benefits in reducing cardiovascular events. However, the lack of universal healthcare coverage for statin therapy in low- to middle-income settings presents a substantial barrier to cost-effective care, particularly for high-risk individuals. These findings underscore the need for policy interventions and expanded access to guideline-directed statin therapy.
Pre–Post Evaluation of a Rural Indonesian Posbindu Cadre-Led Health Promotion Program on Cardiovascular Knowledge, Physical Health, and Mental Well-Being Dewi, Pramitha Esha Nirmala; Tasminatun, Sri; Kurniawan, Nanang; Putri, Hikma Yulia; Galistiani, Githa Fungie; Syaifabila, Imania Afidatus; Ghozali, Muhammad Thesa
Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Vol. 8 No. 11: NOVEMBER 2025 - Media Publikasi Promosi Kesehatan Indonesia (MPPKI)
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/mppki.v8i11.8484

Abstract

Introduction: This study aimed to evaluate the impact of a cadre-led intervention on physical health, cardiovascular knowledge, and mental well-being in rural Indonesian communities. Cardiovascular disease remains a leading cause of mortality in Indonesia, particularly in rural areas with limited healthcare access and low health literacy. With a growing burden of non-communicable diseases in low-resource settings, the objective was to assess a community-based approach addressing early detection and lifestyle modification gaps in the existing literature. Methods: This quasi-experimental one-group pre-post study was conducted over six weeks in a rural Indonesian setting. A total of 91 adult participants were enrolled, and data were collected through anthropometric measurements, biochemical tests, a 15-item cardiovascular knowledge questionnaire, and the Patient Health Questionnaire-9 (PHQ-9) for mental health screening. Ethical approval was obtained from the Medical and Health Research Ethics Committee of the Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Yogyakarta, Indonesia. Results: The primary outcome of the study was the change in cardiovascular risk indicators and knowledge. Findings showed a significant reduction in BMI (mean change = -0.56 kg/m², 95% CI: -0.83 to -0.29, p < 0.001, Cohen’s d = 0.47) and waist circumference (mean change = -0.91 cm, 95% CI: -1.80 to -0.02, p = 0.044, Cohen’s d = 0.28), along with a significant improvement in cardiovascular knowledge scores (mean change = +9.00, 95% CI: +3.44 to +14.56, p = 0.002, Cohen’s d = 0.68). Additionally, PHQ-9 screening showed that 76.9% of participants reported minimal depressive symptoms at the time of assessment. Statistical analyses indicated the effectiveness of the intervention in improving physical and knowledge-related health outcomes. Conclusion: This study contributes to the understanding of health promotion in low-resource rural settings by demonstrating the effectiveness of cadre-led interventions for cardiovascular contexts and the feasibility of integrating mental health screening into community programs. Future studies should explore long-term sustainability and scalability, advancing knowledge in the field of international health.
Evaluation of Outpatient Satisfaction with Pharmaceutical Services in the Era of National Health Insurance Sari, Dewi Mardika; Dewi, Pramitha Esha Nirmala
Interdisciplinary Social Studies Vol. 2 No. 9 (2023): Special Issue
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/iss.v2i9.482

Abstract

Background: The National Health Insurance (JKN) system has been able to improve the health status of the Indonesian people. However, efforts are still needed to accelerate the achievement of health indicators to catch up with other countries. Therefore, the researchers were interested in conducting research related to evaluating outpatient satisfaction with pharmaceutical services in the era of national health insurance at the PKU Muhammadiyah Gamping Hospital. Aim: The purpose of this study is to determine the profile of outpatient satisfaction and at what dimensional pointes outpatients are less satisfied with pharmaceutical services by using national health insurance at PKU Muhammadiyah Gamping hospital   Method: This research is a non-experimental descriptive study with a cross sectional approach. Sampling is carried out prospectively by the purposive sampling method through questionnaires given to the target population. The number of statement items in this study is 29 satisfaction items and 29 expectations items in terms of 5 dimensions. Findings: The level of satisfaction of outpatients with pharmaceutical services in national health insurance users at PKU Muhammadiyah Gamping included the responsiveness dimension of 95.52%, the empathy dimension of 90.49%, the assurance dimension of 90.32%, the reliability dimension of 87.12%, and the tangible dimension of 86.40%. The result of the average value of the respondent's overall satisfaction level was 89.97%. Based on the average results of the value of the outpatient satisfaction level with the pharmaceutical services of national health insurance users at PKU Muhammadiyah Gamping Hospital, this value is included in the category of "very satisfied."
Penerapan Sistem Informasi Pengelolaan Obat di Instalasi Farmasi Rumah Sakit Umum Daerah (RSUD) Menggunakan Pendekatan HOT-FITPenerapan Sistem Informasi Pengelolaan Obat di Instalasi Farmasi Rumah Sakit Umum Daerah (RSUD) Menggunakan Pendekatan HOT-FIT: IMPLEMENTATION OF DRUG MANAGEMENT INFORMATION SYSTEM IN PHARMACY INSTALLATION OF REGIONAL GENERAL HOSPITAL USING HOT-FIT APPROACH Azizatunnisa, Rahmatia; Ghozali, Muhammad Thesa; Ahyar, Zeda Kumala; Dewi, Pramitha Esha Nirmala; Widayati, Aris
JFL : Jurnal Farmasi Lampung Vol. 14 No. 2 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/rvts9708

Abstract

Implementasi lapangan Sistem Informasi Manajemen Pengelolaan Obat (SIM-PO) di instalasi farmasi rumah sakit menuntut keselarasan faktor manusia, organisasi, serta teknologi agar berdampak pada mutu layanan dan efisiensi logistik. Tujuan penelitian ini adalah untuk menganalisis pengaruh dari Human, Organization, dan Technology terhadap keberhasilan penerapan SIM-PO di Instalasi Farmasi Rumah Sakit Umum Daerah (RSUD) yang berlokasi di sebuah kabupaten di Daerah Istimewa Yogyakarta, Indonesia menggunakan metode HOT-FIT. Metode penelitian yang digunakan adalah studi kuantitatif cross-sectional pada 35 tenaga kefarmasian dari berbagai unit kerja, menggunakan kuesioner yang valid dan reliabel; analisis ini dilakukan dengan Partial Least Squares (SmartPLS 3.0). Hasil penelitian membuktikan bahwa ketiga dimensi berpengaruh signifikan terhadap implementasi SIM-PO di instalasi farmasi; domain Human (β=0,364; t=3,231; p=0,0013), Organization (β=0,334; t=2,812; p=0,0051), dan Technology sebagai determinan paling dominan (β=0,442; t=3,676; p=0,0003). Penelitian ini menyimpulkan bahwa keberhasilan implementasi sistem ini ditentukan oleh kualitas teknis dan layanan TI, dukungan organisasi (kebijakan, kepemimpinan, pelatihan), serta kompetensi dan kepuasan pengguna. Selain itu, implikasi praktiknya adalah prioritas peningkatan keandalan sistem informasi obat dan interoperabilitas, program peningkatan kapasitas pengguna berbasis kebutuhan unit, serta tata kelola dan dukungan manajerial yang konsisten.