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All Journal Jurnal Kesehatan Lingkungan indonesia Jurnal Ilmu Dasar Jurnal Natur Indonesia e-Journal Pustaka Kesehatan Althea Medical Journal Indonesian Journal of Urology Journal of Agromedicine and Medical Sciences MNJ (Malang Neurology Journal) Jurnal Ilmiah Kedokteran Wijaya Kusuma Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Majalah Kedokteran Andalas ISM (Intisari Sains Medis) : Jurnal Kedokteran Journal of Health Sciences Medica Hospitalia Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Berkala Penelitian Hayati JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Indonesian Journal of Cancer CoMPHI Journal : Community Medicine and Public Health of Indonesia Journal Makara Journal of Health Research
Heni Fatmawati
Departemen Radiologi, Fakultas Kedokteran Universitas Jember, Jalan Kalimantan 37 Kampus Tegal Boto, Jember, Jawa Timur 68121
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Control & Systems Engineering Dentistry Education Environmental Science Health Professions Immunology & microbiology Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health

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Fibroma of the Vastus Lateralis Tendon Sheath in the Thigh of the 58-year-old Female: A Rare Case Report Heni Fatmawati; Hantonius Hantonius; Antonius Dwi Saputra; Candra Bumi
Journal of Agromedicine and Medical Sciences Vol 10 No 2 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i2.45329

Abstract

Background: Fibroma of the tendon sheath (FTS) is a rare slow-growing noncancerous fibrous tumor that is usually small, painless and involves the upper extremity tendons in young adult males. FTS of the lower extremity is an unusual and underreported variety that poses a diagnostic preoperative challenge. Case description: We report an atypical case of a large fibroma of the vastus lateralis tendon in a 58-year-old female presented with a painful lump in her right thigh within the past six months. Physical examination showed a hard firm mass approximately 6 cm in diameter palpated in the anterior of the lower thigh. The mass was smooth, mobile, solid, and had well-defined borders. There was no adhesion to the skin, redness, or tenderness. MRI showed a 4,2 x 5,8 x 6,2 cm tumor with isointense signals on T1-weighted images (T1WI), heterogeneous hypointense signals on T2-weighted images (T2WI), and hyperintense signals on FatSat images. Biopsy revealed no malignant findings and the tumor had been surgically resected. Imaging studies for FTS have rarely been described, T1WI often show a low signal mass, with slight isointense to hypointense to the muscle. The T2WI’s appearance of FTS is more variable. Conclusion: In spite of rarity, FTS must still be included as a differential diagnosis of a thigh mass especially if the mass is painful and benign-appearing on physical exam and radiology.
Characterization of Classic Meningioma with Use of Conventional Magnetic Resonance and Diffusion Tensor Imaging Fatmawati, Heni; Adji, Novan Krisno; Bumi, Candra; Putri, Komang Yunita Wiryaning
Indonesian Journal of Cancer Vol 18, No 3 (2024): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i3.1133

Abstract

Introduction: The conventional magnetic resonance imaging (MRI) method is widely considered ‘with limited success’ in differentiating the meningioma types but may fail to localize the tumor occupation of white-matter fiber bundles accurately. Diffusion tensor imaging (DTI) is considered as an imaging modality that may elucidate the microstructure of brain tumors. We provide characteristics of meningioma using DTI-based-three-dimensional tracing of white matter to portray meningioma in a noninvasive approach and its structural contact to contiguous tumors and elucidate the influence of occupying lesions on white-matter fiber bundles. Case Presentation: A 28-year-old female presented with visuospatial disturbances and persistent headaches for 2 years. Conventional and advanced MRI studies were performed. Diffusion-weighted Images (DWI) and Apparent Diffusion Coefficient (ADC) values were measured in the lesion using routine MRI sequences. Advanced MRI using DTI was also performed. Conventional MRI outcomes showed tumor parenchyma, peritumoral edema, and compression on the circumnavigated brain tissue. There was hyperintense on DW trace image and isointense on ADC map. On T2-weighted image (T2WI) and Fluid-Attenuated Inversion Recovery (FLAIR) images, there was an increased signal intensity that demonstrated an extra-axial lesion, while T1-weighted imaging signals showed hypointensity. DTI fractional anisotropy (FA) marker is an unclear optic radiation in the concerned area, indicating the shift or destruction of the optic radiation. The mean FA values of solid-enhancing areas of meningioma were 0.28 ± 0.17. Mean ADC values (103 mm2/s) were 0.764 ± 0.172. Conclusions: Classic meningioma in this case has low intratumoral FA and high ADC. DTI displayed that intratumoral microscopic water motion is disorganized.
Determinan Gangguan Muskuloskeletal pada Petani Tembakau di Kelurahan Antirogo Kabupaten Jember Sabila, Selma Naf’an; Fatmawati, Heni; Marchianti, Ancah Caesarina Novi
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 3 No. 3 (2023): Februari
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/comphijournal.v3i3.119

Abstract

One of the most common occupational diseases in the world is musculoskeletal disorders. Tobacco farmers have ahigher risk of musculoskeletal disorders in the form of lower back pain than other farmers because transdermalexposure to nicotine to tobacco farmers has an impact on intervertebral disc nutrition and increased levels of proinflammatory cytokines. The purpose of this study was to analyze the determinants of musculoskeletal disorders intobacco farmers in Antirogo Village, Jember Regency, which is known as the largest tobacco producing district inEast Java. This research is an analytic observational study with a cross-sectional study design. The number of samplesis 53 people based on the Slovin formula with the consecutive sampling method. Musculoskeletal disorders weremeasured using the Nordic Body Map. Data analysis used was descriptive univariate analysis and bivariate analysisusing the Spearman test, Chi-Square 2x3, and Kolmogorov-Smirnov. Significant variables were re-analyzed bymultivariate through ordinal logistic regression analysis. The results showed that most of the tobacco farmers inAntirogo Village, Jember Regency experienced musculoskeletal disorders with moderate complaints (45.3%) mostlyin the waist (33.9%), upper neck (32%), and back (30.1%). Bivariate analysis showed that the significant variableswere age (p= 0.000), years of work (p= 0.000), and work position (p= 0.008). When followed by multivariate analysisit appears that the only significant variable was years of work (p = 0.003). It can be concluded from this study thatthe determinant of musculoskeletal disorders in tobacco farmers in Antirogo Village, Jember Regency is years ofwork.
The Antiallergic Potential of Quercetin Compared With Dexamethasone and Prednisolone against Histamine H1 Receptors in Vernal Keratoconjunctivitis Nugraha Wahyu Cahyana; Ulfa Elfiah; Heni Fatmawati
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 18 No 2 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v18i2.9478

Abstract

Vernal keratoconjunctivitis is an ophthalmological condition that presents significant challenges, especially in children and adolescents, due to chronic inflammation of the conjunctiva and cornea. This inflammation leads to distressing symptoms such as itching, irritation, and photophobia, which severely impact the quality of life. Traditional treatments for this condition often involve antiallergic medications like dexamethasone, prednisolone, and quercetin. However, understanding the precise mechanisms and comparative effectiveness of these treatments is crucial for improving therapeutic outcomes. In this study, protein structure data for dexamethasone (4UDA), prednisolone (8CC1), and quercetin (1JUH) were sourced from the Protein Data Bank (PDB). The crystal structure of the Histamine H1 Receptor (8X5X) was also retrieved from PDB. In silico modeling was carried out using the Cluspro web server to simulate the interactions between these drugs and the receptor. The analysis revealed that quercetin exhibited the lowest Weighted Score of -1810 in cluster 2, outperforming dexamethasone (-1223) and prednisolone (-1372.4), indicating a higher binding potency to the Histamine H1 Receptor. These findings suggest that quercetin has superior potential compared to dexamethasone and prednisolone for binding to Histamine H1 Receptors in the context of vernal keratoconjunctivitis.
Severity of White Matter Lesions Correlate with Small Vessel Ischemic Stroke Zahirah, Mutiara; Fatmawati, Heni; Wiryaning Putri, Komang Yunita
Althea Medical Journal Vol 11, No 4 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v11n4.3338

Abstract

Background: Stroke is the third leading cause of death globally. White matter lesions (WMLs) are often observed on brain imaging such as magnetic resonance imaging (MRI) in healthy elders and are considered as stroke predictors. Increased WMLs volume also affects small vessel stroke with worse disability. This study aimed to explore the correlation between WMLs severity and small vessel stroke subtype in acute ischemic stroke patients.Methods: A cross-sectional descriptive study was conducted using medical record data from June 2018 to October 2022. Simple randomized sampling was used, including stroke patients at Siloam Hospital, Jember. The Fazekas scale categorized WMLs, and magnetic resonance angiography (MRA) confirmed small vessel stroke etiology-based subtype. Two-tailed Spearman's Rank-Order Correlation Coefficient test was employed to describe the relationship between WMLs severity and small vessel stroke subtype. Results: From a total of 65 acute ischemic stroke patients, 39 patients were included, predominantly females (62%), aged less than 55 years old (44%) with a history of hypertension (54%) and diabetes mellitus (59%). Small vessel stroke subtype was found in 64% of patients. There was a positive correlation between WMLs and the small vessel stroke subtype in acute ischemic stroke patients (p=0.02), suggesting that a higher Fazekas scale correlated with the small vessel subtype.Conclusion: The higher the severity of WMLs, the greater the correlation with small vessel stroke subtype. Early detection of small vessel ischemic stroke in patients with severe WML may contribute to early diagnosis and prompt treatment of ischemic stroke. 
EFFICACY OF REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION AS UPPER EXTREMITY MOTOR REHABILITATION THERAPY AFTER STROKE: A SYSTEMATIC REVIEW Purwandhono, Azham; Adji, Novan Krisno; Abrori, Cholis; Fatmawati, Heni; Habibi, Ali
MNJ (Malang Neurology Journal) Vol. 11 No. 1 (2025): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2025.011.01.12

Abstract

Background: The most frequent impairment following a stroke is the hemiparesis of the opposite-side upper extremity. Repetitive Transcranial Magnetic Stimulation (rTMS) is popular in research studies on upper extremity motor rehabilitation after stroke. Information regarding the onset of therapy, duration of therapy, and the type of rTMS in post-stroke upper extremity motor rehabilitation therapy is still spread in various journals, therefore researchers are interested in making this systematic review. Objective: This study aimed to assess the efficacy of rTMS for upper extremity motor rehabilitation after stroke, and had specific aims to compare different treatment timings and durations, as well as evaluating the effectiveness of high-frequency versus low-frequency rTMS. Methods: Literature search was conducted with multiple electronic databases, such as PubMed, ScienceDirect, Cochrane Library, and LinkSpringer. The boolean operator method will be used for the keywords and the synonyms were searched using the Medical Subject Heading (MeSH) database. Critical appraisal and Risk of biases were assessed for each study using The Joanna Briggs Institute (JBI) Critical Appraisal Tools. Data analysis in this systematic review are using descriptive analysis. Results: The included studies consisted of two types of rTMS with varying onset and duration of the therapy. The duration of rTMS therapy consists of 5-18 sessions. In the Upper Extremity Fugl-Meyer Assessment (UE-FMA) based study, High-Frequency (HF) rTMS had significant overall results when compared to sham, whereas Low-Frequency (LF) rTMS therapy still showed contradictory results. HF-rTMS therapy can be performed in acute, subacute, and chronic stroke phases. The duration of HF-rTMS therapy can be done with 5 or 10 sessions, but it still needs further research in order to determine the number of sessions that have the best efficacy. Conclusion: This study show HF-rTMS has better efficacy compared to LF-rTMS for upper extremity motor rehabilitation therapy after stroke.
Hubungan Faktor Risiko dan Kondisi Penyakit Penyerta dengan Gambaran Foto Toraks pada Pasien Terkonfirmasi COVID-19 Fatmawati, Heni; Labibah, Zhafirah Rana; Firdaus, Jauhar
Majalah Kedokteran Indonesia Vol 72 No 3 (2022): Journal of the Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.72.3-2022-629

Abstract

Introduction: COVID-19 is a worldwide health problem with a high mortality rate, especially in patients with risk factors. One type of examination to inspect the severity of COVID-19 patients is a chest radiograph. There is a lack of studies on chest radiography features in Indonesia. This study aims to observe the relationship between age, gender, and comorbid conditions with chest radiography features in COVID-19 confirmed.Method: This study was conducted at dr. Soebandi General Hospital uses a cross-sectional design with medical records as the instrument. Chest radiography examination was performed using BSTI classification. Meanwhile, data were analyzed using Chi-Square and contingency coefficient C.Result: The study included 173 patients: 52% were 40-59 years old, 36,4% were 20-39 years old, and 11,6% were ≥ 60 years old; 56,1% were female and 53,9% were male; 50,9% have comorbidities, with hypertension, diabetes, and COPD were the most type of comorbidities. About 48,6% sample had a normal chest radiograph, 27,7% had a mild severity, 17,3% had a moderate severity, and 6,4% had a severe severity. There was a correlation between age and comorbidity with chest radiography features. Otherwise, no correlation was found between sex and chest radiography features.Conclusion: Age and comorbidity were found as significant risk factors for the severity of chest radiograph in COVID-19 with a moderate correlation. However, no correlation was found between sex and chest radiography features.
Comparison of lipid-lactate levels between brain abscesses and brain tumors through magnetic resonance spectroscopy examination Syafa, Nahdah Ardelia; Fatmawati, Heni; Putri, Komang Yunita Wiryaning; Hairrudin; Adji, Novan Krisno
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 15, No 3, (2024)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol15.Iss3.art7

Abstract

Background: Intracranial masses are masses found in the intracranial space, such as brain abscesses and brain tumors. Magnetic Resonance Spectroscopy (MRS) examination is a noninvasive examination procedure with magnetic resonance regarding chemical composition or metabolites. One of the metabolites examined in MRS is lipid-lactate which will appear or increase if there are certain abnormalities such as in abscesses and brain tumors.Objective: This study analyzed the difference in lipid-lactate levels between brain abscess and brain tumor through MRS examination.Methods: This research adopted an observational analytic approach with a cross-sectional design. Samples in this study were brain abscess and brain tumor patients examined using MRI and MRS at Siloam Jember Hospital from June 2018 to October 2023. The sampling method employed encompassed a total sampling of 45 patients with 15 brain abscesses and 30 brain tumors. Results: The results of this study showed that the lipid-lactate levels of all brain abscess patients increased by 15 patients (100%), while in brain tumors, lipid-lactate levels increased by 19 patients (63.3%) and decreased by 11 patients (36.7%). The mean rank of lipid-lactate levels in brain abscesses was 14101,93 while in brain tumors was 6220,69. The statistical analysis results using the Mann-Whitney comparison test obtained a p-value of 0.008 (<0.05), meaning there is a significant difference.Conclusion: There is a significant difference in lipid-lactate levels in brain abscesses and brain tumors.
Co-Authors A Rudijanto Adji, Novan Krisno Adrian Wibisono Ahmad Rudijanto Al Munawir Ali Santosa Alvin Candra Ancah Caesarina Novi Marchianti Angga Mardro Raharjo Annisa Sarfina Djunaedy Antonius Dwi Saputra Antonius G Santoso Antonius Gunawan S Azham Purwandhono Azham Purwandhono Bagus Hermansyah Brillian Adexa Yudinda Cahyana, Nugraha Wahyu Candra Bumi Candra Bumi Celly Afifah Pramono Cholis Abrori, Cholis Cynthia Parasetiayu Ariesty Desie Dwi Wisudanti Diana Chusna Mufida Dion Krismashogi Dharmawan Dita Diana Parti Edi Junaidi Elly Nurus Sakinah, Elly Nurus Emilia Puspita Sari Endang SW Erma Sulistyaningsih Ghani Silahudin Habibi, Ali Hairrudin Hairrudin Hantonius Hantonius Hendiadi, Bagus Sedya I Nyoman Semita Ida Srisurani Wiji Astuti Ika Aulia Kurniasari Ika Rahmawati Sutejo Irawan Fajar Kusuma Jauhar Firdaus Labibah, Zhafirah Rana Lailatul Maghfiroh M Rasjad Indra Made Devi Desyana Arisandi Muhamad Hasan Muhammad Afiful Jauhani Muhammad Rasjad Indra Ni Made Trismarani Sultradewi Kesuma Nindya Shinta Rumastika Nugraha Wahyu Cahyana Pattipeilohy, Florence Putri, Komang Yunita Wiryaning Putu Ayu Laksmi Lestari Rifaldy Nabiel Erisadana Rizsa Aulia Danesty S Satuman Sabila, Selma Naf’an Santoso, Antonius G Satuman Satuman septa surya wahyudi, septa surya Sofi Aliyatul Himah Sugiyanta Sugiyanta Syafa, Nahdah Ardelia Ulfa Elfiah Wiryaning Putri, Komang Yunita Wiwien Sugih Utami Yehuda Tri Nugroho Supranoto Yoga Setyo Yuli Hermansyah Yunita Armiyanti Zahirah, Mutiara