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Meinar Nur Ashrin
Universitas Hang Tuah
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Efek pemberian astaxanthin (Haematococcus pluvialis) terhadap ukuran diameter pada model ulkus traumatikusThe effect of astaxanthin (Haematococcus pluvialis) on diameter measurement in traumatic ulcer model Anastasia Natasa Aripin; Dwi Andriani; Meinar Nur Ashrin
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 34, No 3 (2022): Desember 2022
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v34i3.38504

Abstract

ABSTRAKPendahuluan: Prevalensi ulser rongga mulut di Indonesia tinggi (96,6%). Astaxanthin yang berasal dari mikroalga hijau Haematococcus pluvialis merupakan salah satu alternatif pengobatan ulser karena adanya sifat antioksidan yang tinggi dan efek anti inflamasinya. Tujuan penelitian menganalisis pengaruh efektivitas pemberian astaxanthin terhadap selisih ukuran diameter ulser hari ke-1 dan hari ke-3 pada model ulkus traumatikus. Metode: Sampel 30 ekor tikus putih Wistar dibagi secara acak menjadi 5 kelompok penelitian yang diberi perlakuan ulkus traumatikus kemudian di terapi selama 3 hari sesuai dengan kelompok masing-masing: K- (kelompok kontrol yang diberi basis gel); K+ (kelompok kontrol yang diberi asam hialuronat); P1 (pemberian astaxanthin 0,1%); P2 (pemberian astaxanthin 0,5%); P3 (pemberian astaxanthin 1%). Data hasil penelitian selanjutnya dilakukan uji one way ANOVA dan dilanjutkan dengan uji Post Hoc LSD dengan p=0,05. Hasil: Hasil analisis uji parametrik One Way ANOVA menunjukkan terdapat perbedaan bermakna (p<0,05) diameter ulser pada hari ke-1 dan hari ke-3. Uji Post Hoc LSD menunjukkan terdapat perbedaan bermakna (p<0,05) antara K- (5,300 ± 2,832) dibandingkan dengan K+ (2,297 ± 1,045), P1(1,740 ± 1,168), P2(1,993 ± 0,738), dan P3 (2,448 ± 1,320). Simpulan: Terdapat pengaruh pemberian astaxanthin gel dalam menurunkan selisih diameter ulser pada hari ke-1 dan hari ke-3 terhadap proses penyembuhan ulkus traumatikus.Kata kunci: antiinflamasi; astaxanthin; haematococcus pluvialis; ulkus traumatikusABSTRACTIntroduction: The prevalence of traumatic ulcers in Indonesia is high (96,6%). Astaxanthin, derived from the green microalgae Haematococcus Pluvialis, is one of the alternative treatments for ulcer healing due to its potent antioxidant and anti-inflammatory effect. This study aimed to analyze astaxanthin’s effectiveness on the difference in the diameter of the ulcer on day 1 and day 3 in a traumatic ulcer model. Methods: Samples of 30 Wistar rats were randomly divided into 5 groups which were treated with traumatic ulcers and then treated for 3 days according to their respective groups: K- (control group given gel base); K+ (control group given hyaluronic acid); P1 (application of 0.1% astaxanthin); P2 (application of 0.5% astaxanthin); P3 (application of 1% astaxanthin). The data results were then carried out with one way ANOVA test, and the Post Hoc LSD test proceeded with p=0,05. Results: The statistical parametric test using One Way ANOVA showed a significant difference (p<0,05) in the diameter ulcer on day 1 and day 3. Post Hoc LSD test showed a significant difference (p<0,05) between K- (5,300  ± 2,832) compare to K+ (2,297 ± 1,045), P1(1,740 ± 1,168), P2(1,993 ± 0,738), and P3 (2,448 ± 1,320). Conclusions: There is an effect of giving astaxanthin gel in reducing the difference in the diameter of the ulcer on day 1 and day 3 on the healing process of traumatic ulcer.Keywords: anti-inflammatory; astaxanthin; haematococcus pluvialis; traumatic ulcer
PENINGKATAN KEBERSIHAN MULUT  MELALUI EDUKASI BERBASIS TOT BAGI GURU DAN ORANG TUA DALAM KEMITRAAN SEKOLAH Sarianoferni Sarianoferni; Noengki Prameswari; Yongki Hadinata; Henu Sumekar; Ayulistya Paramita; Cane Lukisari; Yoifah Rizka Wedarti; Nafiah Nafiah; Twi Agnita Cevanti; Agni Febrina Pargaputri; Dianty Saptaswari; Meinar Nur Ashrin; Ghita Hadi Hollanda; Aprilia Aprilia; Dwi Setyaningtyas
BESIRU : Jurnal Pengabdian Masyarakat Vol. 3 No. 1 (2026): BESIRU : Jurnal Pengabdian Masyarakat, Januari 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v3i1.2059

Abstract

Dental caries in children remains a significant public health problem in Indonesia, particularly among primary school-aged children. Limited oral health literacy and insufficient involvement of teachers and parents in oral hygiene guidance contribute to the high prevalence of dental caries. This study aimed to enhance children’s oral hygiene knowledge and practices through Training of Trainers (ToT)-based education for teachers and parents within a partnership between the Faculty of Dentistry, Hang Tuah University, and El Rahma Islamic Boarding School, Surabaya. A pretest–posttest design was applied, involving fifth-grade students as research subjects. Teachers and parents received ToT-based training delivered by dental professionals and subsequently provided oral health education to students. Knowledge levels were assessed using questionnaires administered before and after the intervention and analyzed using the Wilcoxon Signed-Rank Test. The results demonstrated a significant increase in students’ mean knowledge scores, from 58.14 ± 21.30 at pretest to 77.21 ± 18.30 at posttest (p < 0.05). In addition, partner satisfaction questionnaires indicated a very high level of satisfaction with the program implementation. In conclusion, ToT-based oral health education involving teachers and parents is effective in improving children’s oral hygiene knowledge and has the potential to promote sustainable oral health behavior changes within the school environment.
Co-Authors Agni Febrina Pargaputri Anastasia Natasa Aripin Andriani, Dwi Aprilia Aprilia Cane Lukisari Dwi Setyaningtyas Ghita Hadi Hollanda Henu Sumekar Nafiah Nafiah Noengki Prameswari Saptaswari, Dianty Sarianoferni Sutarto, Ayulistya Paramita Twi Agnita Cevanti Yoifah Rizka Wedarti Yongki Hadinata