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All Journal Medical Laboratory Technology Journal Jurnal Skala Kesehatan Medika Kartika : Jurnal Kedokteran dan Kesehatan JWM (JURNAL WAWASAN MANAJEMEN) Jurnal Rakat Sehat : Pengabdian Kepada Masyarakat Jurnal Karya Generasi Sehat
Tini Elyn Herlina
Poltekkes Kemenkes Banjarmasin
Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary Other

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Journal : Medical Laboratory Technology Journal

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Immune Response to anti-HBs Antibodies in Health Workers Following Hepatitis B Vaccination Dinna Rakhmina; Wahdah Norsiah; Tini Elyn Herlina; Norhafizah Mulia Sari; Reza Pertiwi; Rizka Ariani; Sahri Rahman
Medical Laboratory Technology Journal Vol. 7 No. 2 (2021): December
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (313.363 KB) | DOI: 10.31964/mltj.v7i2.418

Abstract

According to Regulation No. 53 of 2015 of the Minister of Health of the Republic of Indonesia, a high risk of HBV infection in health workers is a problem that requires attention, and vaccination knowledge is critical to reducing these risk factors. Furthermore, because some people do not produce a sufficient antibody-forming (anti-HBs) response to HBsAg, testing for evidence of protective immunity against hepatitis B vaccination is required (Hepatitis B Surface Antigen). The purpose of the study was to determine the mapping of the characteristics of anti-HBs antibodies response after hepatitis B vaccination in health workers in terms of age, gender, ethnicity, smoking habits, obesity, vaccination frequency, last time of vaccination. Sixty vaccinated health workers were used to creating the research sample. Anti-HBs levels/titers in serum were measured using the Enzyme-Linked Immunosorbent Assay (ELISA) method, and a questionnaire was used to compile the data for this study. Age, gender, smoking, obesity, and vaccination dose were all used to map the outcomes of the anti-HBs antibody immune response study. Anti-HBs antibody response in health workers was graded as poor in 36 people (60%) and strong in 24 (40%). Regarding ethnic origin, lifestyle, obesity, and vaccination dose (frequency), there was no significant link between post-vaccination anti-HBs antibody response in health workers. In terms of age and gender, there is a strong association between post-vaccination anti-HBs antibody responses in health workers. Low antibody titers should be revaccinated to enhance anti-HBs titers, and health workers who smoke should quit because it reduces the levels of anti-HBs titers produced clinically.
Hematological Effects of Vigna unguiculata subsp. cylindrica in Anemic Mice: An Experimental Study Norsiah, Wahdah; Thuraidah, Anny; Herlina, Tini Elyn
Medical Laboratory Technology Journal Vol. 11 No. 2 (2025): December
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v11i2.687

Abstract

Anemia is a global health problem that impairs cognitive function, physical performance, and maternal–child health. This study aimed to evaluate the hematological effects of Vigna unguiculata subsp. cylindrica (Nagara Bean) as a potential functional food in sodium nitrite (NaNO₂)-induced anemic mice. Thirty-three male BALB/c mice (8–12 weeks, 25–30 g) were randomly assigned into six groups: normal control (K), negative control (K−, anemia-induced), positive control (K+, iron-supplemented), and three treatment groups (P1, P2, P3) that received Nagara Bean-based feed for 1, 2, and 3 weeks, respectively. Hemoglobin (Hb), hematocrit (Hct), and red blood cell (RBC) levels were measured using Point-of-Care Testing (POCT) and manual cell counting. The results showed increases in Hb, Hct, and RBC across the treatment groups; however, statistical analysis indicated that these improvements were primarily associated with the duration of feed administration rather than treatment type. The greatest hematological improvement was observed after two weeks of feeding (P2). These findings indicate that Nagara Bean supplementation supports hematological recovery in anemic mice. The results suggest that Vigna unguiculata subsp. cylindrica has potential as a natural, affordable, and locally available source of bioavailable iron for anemia prevention and dietary intervention programs.
Co-Authors Ahmad Alim Bachri Ahmad Muhlisin Aini Luthfiah Hayati Alda Nia Amalia Putri Amalia Putri, Amalia Anny Thuraidah, Anny Azizah Mustika Khatami Dinna Rakhmina Dinna Rakhmina Dinna Rakhmina, Dinna Erfan Roebiakto, Erfan H. Haitami Hafidh, Muhammad Haitami Haitami Khatami, Azizah Mustika Muhammad Hafidh Muhammad Rivai Nia, Alda Norhafizah Mulia Sari Rabiyatul Adawiyah Rabiyatul Adawiyah Rizka Ariani Sahri Rahman Shoffa Shafira, Farah Wahdah Norsiah wahdah norsiah Wahdah Norsiah, Wahdah Yayuk Kustiningsih