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Korelasi antara Skor Intracerebral Hemorrhage (ICH) dengan Mortalitas Pasien Perdarahan Intraserebral di RSUD Ulin Banjarmasin Awanis, Marini; Sikumbang, Kenanga Marwan; Asnawati, Asnawati
Jurnal Neuroanestesi Indonesia Vol 10, No 1 (2021)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (128.619 KB) | DOI: 10.24244/jni.v10i1.266

Abstract

Latar Belakang dan Tujuan: Perdarahan intraserebral (PIS) merupakan kejadian medis yang meningkatkan angka kematian dan kecacatan tinggi. Secara teori, mortalitas PIS dapat diprediksi dengan menggunakan komponen skor Intracerebral Hemorrhage (ICH). Tujuan penelitian ini untuk mengetahui bagaimana korelasi antara skor ICH dengan mortalitas pasien PIS di RSUD Ulin Banjarmasin. Subjek dan Metode: Penelitian ini bersifat observasional analitik dengan pendekatan cross sectional. Sebanyak 53 sampel didapatkan secara consecutive sampling. Data hasil penelitian diuji dengan uji Regresi Logistik.Hasil: Dalam penelitian ini pasien skor ICH 0 meninggal sebanyak 15%, 36% skor ICH 1, 71% skor ICH 2, 86% skor ICH 3 dan 100% skor ICH 4 dan 5. Hasil analisis data penelitian ini, diperoleh OR = 0,02; 0,06; 0,3 untuk masing-masing skor ICH 1, 2 dan ?3; dengan p=0,001. Simpulan: Terdapat korelasi yang sangat signifikan dan hubungan positif antara skor ICH dengan mortalitas pasien PIS di RSUD Ulin Banjarmasin, sebagai prediktor independen.Correlation between ICH Score with ICH Patients Mortality at Ulin General Hospital BanjarmasinAbstractBackground and Objective: Intracerebral hemorrhage (ICH) is the medical events that increases the mortality and disability. Theoretically, mortality can be predict by ICH scores components. The purpose of this study is to determine the correlation between ICH scores and mortality of ICH patients in Ulin General Hospital Banjarmasin. Subject and Method: This research is an analytic observational with cross sectional approach. A total of 53 samples were obtained by consecutive. Data analysis of this study used the Logistic Regression test.Result: In this study, it was found that patients with ICH score 0 died 15%, 36% score 1, 71% score 2, 86% score 3 and 100% score 4 and 5. Data analysis of this study showing OR= 0,02; 0,06; 0,3 for ICH score 1, 2 and ?3 respectively; with p=0,001. Conclusion: There is a very significant correlation and enough positive relationship between the ICH score and mortality of ICH patients in Ulin General Hospital Banjarmasin, as independent predictor.
Effect of Striped Catfish (Pangasianodon Hypophthalmus) Supplementation on Mice (Mus Musculus) Colon Wibowo, Agung Ary; Hosea, Nathania; Triawanti, Triawanti; Lahdimawan, Ardik; Priyono, Sasongko Hadi; Siagian, Andreas Marojohan Haratua; Sikumbang, Kenanga Marwan
Majalah Kedokteran Bandung Vol 57, No 4 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4395

Abstract

Diet affects the microbial structure of the gut and human metabolic functions. Disruption of nutrient sources that produce short-chain fatty acids (SCFA) will cause atrophy and inflammation of the colonic mucous. Striped catfish (Pangasianodon hypophthalmus) increases SCFA production because of its high levels of carbohydrates, protein, and fat content. This experimental study used 50 male mice (Mus musculus) aged 3 months old, weighing 20-30 grams, divided into control group (given standard feed) and treatment group (given mixture of standard feed and striped catfish meat). The mice were given treatment for eight (8) weeks at the Faculty of Medicine and Health Sciences, Lambung Mangkurat University, Indonesia, from May to July 2024 and then sacrificed. Colon biopsies were examined using hematoxylin-eosin staining to determine crypt morphology, number of goblet cells, and number of inflammatory cells at Ulin Hospital Banjarmasin, Indonesia, from July until October 2024. The crypt morphology in the treatment group showed fewer abnormalities (5 out of 25 samples) compared to the control group (11 out of 23 samples) (p=0.041) with a moderate correlation (p=0.295). The number of goblet cells was higher in the treatment group (200.4±54.1) than in the control group (134.5±34.3) (p=0.001) with a strong correlation (p = 0.616). The number of inflammatory cells was lower in the treatment group (9.9±4.4) than in the control group (27.6±7.8) (p=0.001) with a very strong correlation (p=0.838). Thus, striped catfish supplementation reduces morphological abnormalities of the crypts and the number of inflammatory cells, as well as increases the number of goblet cells in the colon of mice.