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All Journal Berkala Kedokteran Sebatik Jurnal EnviScience (Environment Science) Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal ABDINUS : Jurnal Pengabdian Nusantara Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat: Humanity and Medicine CoMPHI Journal : Community Medicine and Public Health of Indonesia Journal Journal of Pharmaceutical and Sciences. Jurnal Ilmiah Kesehatan Scientific Journal of Dermatology and Venereology Holistik Jurnal Kesehatan
Kusumah, Irwin Priyatna
Universitas Ciputra
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Veterinary

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Hubungan Penggunaan Larvasida Rumah Tangga dengan Keberadaan Nyamuk Pra-dewasa di Bak Kamar Mandi: Studi di Kelurahan Sememi, Surabaya Dewi Lestari Wibowo; Hanna Tabita Hasianna Silitonga; Hebert Adrianto; Irwin Prijatna Kusumah
Jurnal EnviScience (Environment Science) Vol. 10 No. 1 (2026): Environmental Health: Multidisciplinary Approaches to Improving Air, Water, an
Publisher : Universitas Islam Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30736/jev.v10i1.949

Abstract

Keberadaan nyamuk pra-dewasa di lingkungan sekitar masyarakat seperti bak kamar mandi berpotensi menularkan penyakit yang dibawa oleh vektor nyamuk, yaitu DBD. Salah satu cara menekan angka nyamuk pra-dewasa adalah dengan menggunakan larvasida rumah tangga. Penelitian ini bertujuan untuk hubungan penggunaan larvasida rumah tangga dengan nyamuk pra-dewasa di bak kamar mandi di Kelurahan Sememi Surabaya. Penelitian ini menggunakan desain observasional analitik dengan pendekatan Cross-sectional dengan sampel 97 rumah tangga di Kelurahan Sememi Surabaya. Pengumpulan data menggunakan kuesioner dengan lima pertanyaan mengenai data demografi dan satu pertanyaan mengenai penggunaan larvasida rumah tangga dan observasi bak kamar mandi secara langsung. Analisis data dilakukan secara univariat dan bivariat dengan menggunakan uji chi-square. Hasil penelitian menunjukkan bahwa tidak terdapat hubungan antara penggunaan larvasida rumah tangga dengan keberadaan nyamuk pra-dewasa di bak kamar mandi di Kelurahan Sememi Surabaya (p > 0,338). Disimpulkan bahwa penggunaan larvasida rumah tangga belum menunjukkan hubungan yang signifikan dengan keberadaan nyamuk pra-dewasa di bak kamar mandi, sehingga diperlukan strategi pengendalian lain serta penelitian lanjutan untuk mengkaji faktor-faktor lain yang memengaruhinya. Kata kunci : Demam Berdarah Dengue; larvasida; nyamuk pra-dewasa; rumah tangga  
Lower Facial Skin Hydration is Associated with Greater Acne Vulgaris Severity in Indonesian University Students: A Cross-Sectional Study Febriana; Stefani Nurhadi; Irwin Priyatna Kusumah
Scientific Journal of Dermatology and Venereology Vol. 3 No. 2 (2025): Scientific Journal of Dermatology and Venereology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjdv.v3i2.266

Abstract

Background: Acne vulgaris is increasingly recognized as a skin-barrier disease, yet data linking facial hydration to graded severity in tropical Asian young adults are scarce. Objective: To determine the association between facial skin hydration and acne vulgaris severity in Indonesian university students. Methods: In this cross-sectional analytic study, 33 students aged 17–25 years with acne vulgaris were enrolled by purposive sampling at a Surabaya dermatology clinic. Facial stratum corneum hydration was measured by capacitance and classed as dry (<35%), normal (35–50%) or moist (>50%); severity was graded by the Lehmann/Indonesian Acne Expert Meeting criteria. Associations were tested with chi-square, odds ratios, Spearman correlation, multivariable logistic regression and receiver-operating-characteristic (ROC) analysis. Results: Participants were predominantly female (69.7%); 54.5% had dry skin and 60.6% had moderate acne, with no severe cases. Lower hydration was significantly associated with greater severity (χ²=9.641, p=0.008; Cramér's V=0.541). Dry skin conferred ten-fold higher odds of moderate acne (OR=10.00, 95% CI 1.94–51.54), and each 10% reduction in moisture independently raised the odds (adjusted OR=3.87, 95% CI 1.39–10.72, p=0.009). Facial moisture discriminated moderate acne well (AUC=0.792; Spearman ρ=−0.536, p=0.001). Conclusion: Lower facial hydration is independently associated with more severe acne, supporting barrier-directed, non-comedogenic moisturization as an adjunct in acne care for Fitzpatrick III–V skin.
Analisis Efektivitas Nanocurcumin Terhadap Ekspresi TNF-α Dan Diameter Lesi Pada Mencit (Mus musculus) Yang Diinduksi Endometriosis Komang Ayu Vanessa Dharma; Florence Pribadi; Irwin Priyatna Kusumah
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1249

Abstract

Endometriosis is a chronic gynecological disease characterized by the growth of endometrial-like tissue outside the uterus, which triggers local inflammation and lesion progression. The pathological process involves increased proinflammatory cytokines, including TNF-α, and activation of proliferative and angiogenic pathways. Nanocurcumin, with higher bioavailability compared to conventional curcumin, is known to have the potential to modulate inflammation and inhibit ectopic tissue growth. This study aimed to analyze the effect of nanocurcumin at a dose of 10 mg/kgBW on TNF-α expression and endometriosis lesion diameter in endometriosis-induced mice. The laboratory experimental study used a post-test only control group design with three treatment groups (control, nanocurcumin after induction, and nanocurcumin before induction), each consisting of 10 mice. TNF-α expression was measured using the ELISA method, while lesion diameter was assessed macroscopically. Data analysis was performed using the Shapiro–Wilk normality test, Levene's homogeneity test, ANOVA, and Tukey's extended test. The results showed no significant difference in TNF-α levels between groups (p = 0.933). However, there was a significant difference in endometriosis lesion diameter (p < 0.001), with the nanocurcumin group showing the greatest lesion shrinkage compared to the control and other treatment groups. Nanocurcumin significantly reduced the diameter of endometriosis lesions in mice, although it did not significantly reduce serum TNF-α levels. These findings suggest that the therapeutic effects of nanocurcumin may be mediated through local mechanisms that are not fully reflected in serum biomarkers.
Co-Authors Agnes Atmadjaja Atalya Riawani Iring Ayesha, Dezaundra Banjarnahor, Dharma PP Bella Meylani Lifindra Billy Daniel Messakh Denys Putra Alim Desy Natalia F. Maskim Dewi Lestari Wibowo Dharma PP Banjarnahor Dion, Aldy Dyaniko Prio Basudewo Endik, Ony Intan Tsalsa Cahyaning Febriana Ferdinand A Tannus Florence Pribadi Florence Pribadi Gani, Wilson Gunawan, Monica Jennifer Hanna Tabita Hasianna Silitonga Hardianto, Reynaldi Hebert Adrianto Helen Octavia Helen Octavia Djoenaydy Hendera Henderi Heru Cahjono Kevin Luke Komang Ayu Vanessa Dharma Laila, Najmul Lyndia Effendy Manurung, Riska Enjelica Nidom, Astria Novitasari Nimas Pristiwanto D S Octavia, Helen Palloan, Glory Ta’bi Purwakaning Purnomo Agung Raden Roro Shinta Arisanti Rafa Daniel Walukow Raniar Nasyira Rosiana, Vivian Salmon Charles Pardomuan Tua Siahaan Saskia Dyah Handari Setyawan, Yuswanto Stefani Nurhadi Susanto, Vivian Rosiana Tandoyo, Eric Thang, Belinda Wijaya Victor Kurniawan Yuwono Wahid, Ridzal Wakas, Berlian Ester