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PENYULUHAN PEMANFAATAN SAYUR KUBIS MENJADI TEPUNG SAYUR DI PEKON WASPADA, KEC. SEKINCAU, LAMPUNG BARAT Afriyani Afriyani; Selvi Marcellia; Dwi Aulia Ramdini; Ervina Damayanti; Muhammad Fitra Wardhana Sayoeti
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 11 No. 1 (2026): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmrj.v11i1.3949

Pekon Waspada adalah desa yang terletak di Kecamatan Sekincau, Kabupaten Lampung Barat dengan masyarakatnya sebagian besar berprofesi sebagai petani. Jenis sayuran yang paling banyak ditanam adalah kubis. Sayuran kubis oleh petani banyak diperjualkan kepada pengepul dalam bentuk segar, namun harga jual maupun volume penjualannya terhitung masih cukup kecil. Selain itu, jika tidak laku kubis yang baru dipanen akan dibiarkan saja padahal sayuran kubis memiliki umur simpan yang pendek mengingat kandungan air yang tinggi. Oleh karenanya, kami mengadakan penyuluhan pengembangan produk berbahan dasar sayur kubis guna meningkatkan umur simpan dan nilai ekonomis, salah satunya adalah dengan mengolah menjadi tepung sayur melalui metode pengeringan. Adapun tahapan yang dilakukan dalam kegiatan sosialisasi terdiri dari persiapan, riset dan formulasi produk, penyuluhan pembuatan tepung sayur. Diharapkan dari kegiatan sosialisasi ini dapat memberikan pengetahuan kepada masyarakat khususnya ibu-ibu kader PKK dan KWT dengan memanfaatkan pengolahan tingkat lanjut kubis sebagai peluang usaha serta dari tepung sayur kubis ini dapat menjadi salah satu cara untuk memperpanjang umur simpan kubis sehingga mampu mengurangi terbuangnya kubis secara percuma.

UJI EFEKTIVITAS EKSTRAK KULIT JERUK NIPIS (Citrus aurantifolia) TERHADAP BAKTERI Staphylococcus aureus DAN Escherichia coli DALAM SEDIAAN GEL HAND SANITIZER Iwang Davi Setiawan; Ade Maria Ulfa; Selvi Marcellia; Indah Aprianti; Artha Meithia; Arta Arum Cahyani
Jurnal Analis Farmasi Vol 11, No 1 (2026): JURNAL ANALIS FARMASI
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jaf.v11i1.25708

Hand sanitizer gel has been commonly used as on of the ways to maintain health and hand sanity which is practical and easy to carry along. One of the plant whichi has an anti-bacteria is lime (Citrus aurantifolia). The purpose of this study was to acknowledge lime peel extract's resistance inside a hand sanitizer gel toinhibit the growth od Staphylococcus aureus dan Escherichia coli. The lime peel extraction used maceration method with 96% ethanol solvent. Bacterial inhibition testing on lime peel extract used by the disk method and on hand sanitizer gel preparations used by the wells method. The concentration of lime peel extract used was 20%, 25%, 30%, 35%, 40% and positive control with an average inhibition zone of 8.91 mm, 10.19 mm, 10.42 mm, 10.67 mm , 11.00 mm, 29.16 mm against Staphylococcus aueurus bacteria and 6.89 mm, 8.39 mm, 9.31 mm, 9.72 mm, 9.97 mm and 24.22 mm against Escherichia coli bacteria. In the preparation of hand gel sanitizer, the concentrations used were 20%, 22%, 25% and positive control with an average inhibition zone of 9.11 mm, 9.42 mm, 10.23 mm, 10.40 mm against Staphylococcus aueurus bacteria and 7.21 mm, 8.11 mm, 8.50 mm and 10.35 mm against Escherichia coli bacteria. The antibacterial test results were analyzed using ANOVA, the results of statistical analysis on lime peel extract and hand sanitizer gel of lime peel extract showed a significant inhibition zone difference 0,000 (P = 0.05) between all concentrations of lime peel extract. Lime peel extract in a hand sanitizer gel was effective in inhibiting the bacteria Staphylococcus aureus and Escherichia coli.

UJI EFEKTIVITAS EKSTRAK KULIT JERUK NIPIS (Citrus aurantifolia) TERHADAP BAKTERI Staphylococcus aureus DAN Escherichia coli DALAM SEDIAAN GEL HAND SANITIZER Iwang Davi Setiawan; Ade Maria Ulfa; Selvi Marcellia; Indah Aprianti; Artha Meithia; Arta Arum Cahyani
Jurnal Analis Farmasi Vol 11, No 1 (2026): JURNAL ANALIS FARMASI
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jaf.v11i1.25708

Hand sanitizer gel has been commonly used as on of the ways to maintain health and hand sanity which is practical and easy to carry along. One of the plant whichi has an anti-bacteria is lime (Citrus aurantifolia). The purpose of this study was to acknowledge lime peel extract's resistance inside a hand sanitizer gel toinhibit the growth od Staphylococcus aureus dan Escherichia coli. The lime peel extraction used maceration method with 96% ethanol solvent. Bacterial inhibition testing on lime peel extract used by the disk method and on hand sanitizer gel preparations used by the wells method. The concentration of lime peel extract used was 20%, 25%, 30%, 35%, 40% and positive control with an average inhibition zone of 8.91 mm, 10.19 mm, 10.42 mm, 10.67 mm , 11.00 mm, 29.16 mm against Staphylococcus aueurus bacteria and 6.89 mm, 8.39 mm, 9.31 mm, 9.72 mm, 9.97 mm and 24.22 mm against Escherichia coli bacteria. In the preparation of hand gel sanitizer, the concentrations used were 20%, 22%, 25% and positive control with an average inhibition zone of 9.11 mm, 9.42 mm, 10.23 mm, 10.40 mm against Staphylococcus aueurus bacteria and 7.21 mm, 8.11 mm, 8.50 mm and 10.35 mm against Escherichia coli bacteria. The antibacterial test results were analyzed using ANOVA, the results of statistical analysis on lime peel extract and hand sanitizer gel of lime peel extract showed a significant inhibition zone difference 0,000 (P = 0.05) between all concentrations of lime peel extract. Lime peel extract in a hand sanitizer gel was effective in inhibiting the bacteria Staphylococcus aureus and Escherichia coli.

POLYGENIC RISK SCORE SEBAGAI PREDIKTOR DIABETES MELLITUS TIPE 2: SYSTEMATIC RIVIEW Ni Ketut Diah Ayu Pramisswari; Ety Apriliana; Selvi Marcellia; Putu Ristyaning Ayu Sangging
Nusantara Hasana Journal Vol. 5 No. 8 (2026): Nusantara Hasana Journal, January 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i8.1881

Type 2 diabetes mellitus (T2DM) is a multifactorial metabolic disease with a significant genetic contribution. Polygenic risk score (PRS) has been developed to integrate the cumulative effects of multiple genetic variants to improve T2DM risk prediction. This Systematic review aimed to evaluate the role of PRS in predicting T2DM incidence, disease progression, and related complications across different populations. This study was conducted in accordance with the PRISMA guidelines, with a literature search performed using the PubMed database and keywords related to PRS and T2DM. Included studies were observational in design and assessed the association between PRS and T2DM incidence or clinical outcomes. Three main studies with case-control, cross-sectional, and cohort designs were analyzed. The results demonstrated that PRS was significantly associated with increased T2DM risk, disease progression, and metabolic complications such as liver fibrosis, including in the context of organ transplantation. Integration of PRS with traditional clinical risk factors improved predictive performance. PRS has the potential to support precision-based T2DM risk stratification, although further cross-population validation is still required.

Uji efektivitas ekstrak kulit buah mahoni (swietenia mahagoni l.) terhadap bakteri salmonella thyphi Mariska Mulya Safitri; Selvi Marcellia; Tutik Tutik
JOURNAL OF Pharmacy and Tropical Issues Vol. 2 No. 2 (2022): December Edition 2022
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/pti.v2i02.322

Background:Typhoid fever is a disease that arises due to infection with pathogenic bacteria such as Salmonella typhi. The plant commonly used by the community to cure typhoid fever is by using mahogany fruit skin. Purpose: To identify the effectiveness of mahogany rind extract as an antibacterial against Salmonella typhi bacteria and determine the concentration of mahogany rind extract against Salmonella typhi bacteria. Methods: This study used the soxhlet extraction method with 96 percent ethanol as solvent. Results: The effectiveness obtained from the mahogany rind extract test (Swietenia mahagoni L) was 29.6 percent, the extraction result was 6.7 percent, the phytochemical screening results of the mahogany rind extract obtained flavonoid compounds, saponins, phenolics, tannins and alkaloids. The results of the effectiveness of mahogany skin extract (Switenia mahagoni L) was effective at a concentration of 10 percent with an inhibition zone of 8.5 mm which had a moderate inhibitory response. Conclusion: Ethanol extract of mahogany peel (Switenia mahagoni L) has properties that can inhibit the geowth of Salmonella typhi bacteria. Keywords: Effectiveness; Mahogany Fruit Peel Extract (Swietenia Mahagoni L.); Salmonella Typii. Pendahuluan: Demam tifoid adalah salah satu penyakit yang timbul akibat infeksi bakteri patogen seperti bakteri Salmonella typhi.tanaman yang biasa digunakan oleh masyarakat untuk menyembuhkan demam tifoid yaitu dengan menggunakan kulit buah mahoni. Tujuan: Untuk mengidentifikasi efektivitas ekstrak kulit buah mahoni sebagai antibakteri pada bakteri Salmonella typhi dan menentukan konsentrasi ekstrak kulit buah mahoni terhadap bakteri Salmonella typhi. Metode: Penelitian ini menggunakan metode ekstraksi sokletasi dengan pelarut etanol 96 persen. Hasil: Efektivitas yang diperoleh dari uji ekstrak kulit buah mahoni (Swietenia mahagoni L) yaitu 29,6 persen,Hasil ekstraksi diperoleh 6,7 persen, pada hasil skrining fitokimia ekstrak kulit buah mahoni diperoleh senyawa flavonoid, saponin, fenolik, tanin dan alkaloid. Hasil efektivitas ekstrak kulit buah mahoni (Switenia mahagoni L) sudah efektiv pada konsentrasi 10 persen dengan zona hambat 8,5 mm yang memiliki respon hambat sedang. Simpulan: Ekstrak etanol kulit buah mahoni (Swietenia mahagoni L) memiliki sifat yang dapat menghambat pertumbuhan bakteri Salmonella typhi.

Uji efektivitas ekstrak kulit buah mahoni (Swietenia Mahagoni L.) sebagai larvasida aedes aegypti dengan metode sokletasi Bella Tasya Salsabila; Selvi Marcellia; Nofita Nofita
JOURNAL OF Pharmacy and Tropical Issues Vol. 4 No. 2 (2024): December Edition 2024
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/pti.v4i2.535

Background: Swietenia mahagoni (L.) known as mahogany is an example of a plant that has larvicidal effectiveness. Mahogany rind contains flavonoids, saponins, tannins, alkaloids, phenols, steroids and terpenoids. Secondary metabolite compounds that can be used as larvicides, namely, flavonoids which work by causing wilting of the nerves and damage to the respiratory system and causing the larvae to be unable to breathe and eventually die Purpose: To find out whether mahogany rind (Swietenia mahagoni (L.) is effective as a larvicide on Aedes aegypti mosquitoes and to find out what the LC50 value is in the effectiveness test on mahogany rind (Swietenia mahagoni (L.) as a larvicide on Aedes aegypti mosquitoes). Methods: Mosquitoes were divided into 6 groups, namely, positive control group, concentration of 0.5%, 1%, 2%, 4% and negative control. Results: The yield of mahogany peel extract was 6.7%. The results of the ethanol extract of mahogany fruit has activity as a larvicidal from a concentration of 2% and 4% already has an effectiveness almost equivalent to the positive control. The LC50 value indicates the ability of the ethanol extract of mahogany fruit to be 0.244%. Then the data obtained was then tested using the One Way ANOVA test and the LSD (Least Significance Different) Post Hoc test to determine whether there were differences in each concentration. Conclusion: The ethanol extract of mahogany (Swietenia mahagoni L.) peel has highly toxic properties in killing Aedes aegypti larvae. Keywords: Mahogany Fruit Peel; larvicides; Aedes aegypti; Soxhletation Method. Pendahuluan: Swietenia mahagoni (L.) yang dikenal sebagai mahoni merupakan salah satu contoh tanaman yang memiliki efektivitas larvasida. Kulit buah mahoni mengandung flavonoid, saponin, tanin, alkaloid, fenol, steroid dan terpenoid. Senyawa metabolit sekunder yang dapat digunakan sebagai larvasida yaitu, flavonoid yang bekerja dengan cara menimbulkan kelayuan pada syaraf serta kerusakan pada sistem pernapasan dan mengakibatkan larva tidak bisa bernapas dan akhirnya mati Tujuan: Untuk mengetahui apakah kulit buah mahoni (Swietenia mahagoni (L.) efektif sebagai larvasida pada nyamuk Aedes aegypti dan untuk mengetahui berapakah nilai LC50 pada uji efektivitas pada kulit buah mahoni (Swietenia mahagoni (L.) sebagai larvasida pada nyamuk Aedes aegypti. Metode: Nyamuk dibagi menjadi 6 kelompok yaitu, kelompok kontrol positif, konsentrasi 0,5%, 1%, 2%, 4% dan kontrol negatif. Hasil: Rendemen ekstrak kulit buah mahoni didaptakan sebesar 6,7%. Hasil ekstrak etanol buah mahoni memiliki aktivitas sebagai larvasida dari konsentrasi 2% dan 4% sudah memiliki efektivitas hampir setara dengan kontrol positif. Nilai LC50 menunjukkan kemampuan ekstrak etanol buah mahoni sebesar 0,244%. Kemudian data yang didapatkan lalu diuji menggunakan uji One Way ANOVA dan uji Post Hoc LSD (Least Significance Different) untuk mengetahui adanya perbedaan pada tiap konsentrasi. Simpulan: Ekstrak etanol kulit buah mahoni (Swietenia mahagoni L.) memiliki sifat sangat beracun dalam membunuh larva Aedes aegypti. Kata Kunci: Kulit Buah Mahoni; Larvasida; Aedes Aegypti; Metode Sokletasi.

Uji efektivitas ekstrak kulit buah mahoni (swietenia mahagoni l.) terhadap bakteri salmonella thyphi Mariska Mulya Safitri; Selvi Marcellia; Tutik Tutik
JOURNAL OF Pharmacy and Tropical Issues Vol. 4 No. 2 (2024): December Edition 2024
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/pti.v4i2.536

Background:Typhoid fever is a disease that arises due to infection with pathogenic bacteria such as Salmonella typhi. The plant commonly used by the community to cure typhoid fever is by using mahogany fruit skin. Purpose: To identify the effectiveness of mahogany rind extract as an antibacterial against Salmonella typhi bacteria and determine the concentration of mahogany rind extract against Salmonella typhi bacteria. Methods: This study used the soxhlet extraction method with 96 percent ethanol as solvent. Results: The effectiveness obtained from the mahogany rind extract test (Swietenia mahagoni L) was 29.6 percent, the extraction result was 6.7 percent, the phytochemical screening results of the mahogany rind extract obtained flavonoid compounds, saponins, phenolics, tannins and alkaloids. The results of the effectiveness of mahogany skin extract (Switenia mahagoni L) was effective at a concentration of 10 percent with an inhibition zone of 8.5 mm which had a moderate inhibitory response. Conclusion: Ethanol extract of mahogany peel (Switenia mahagoni L) has properties that can inhibit the geowth of Salmonella typhi bacteria. Keywords: Effectiveness; Mahogany Fruit Peel Extract (Swietenia Mahagoni L.); Salmonella Typii. Pendahuluan: Demam tifoid adalah salah satu penyakit yang timbul akibat infeksi bakteri patogen seperti bakteri Salmonella typhi.tanaman yang biasa digunakan oleh masyarakat untuk menyembuhkan demam tifoid yaitu dengan menggunakan kulit buah mahoni. Tujuan: Untuk mengidentifikasi efektivitas ekstrak kulit buah mahoni sebagai antibakteri pada bakteri Salmonella typhi dan menentukan konsentrasi ekstrak kulit buah mahoni terhadap bakteri Salmonella typhi. Metode: Penelitian ini menggunakan metode ekstraksi sokletasi dengan pelarut etanol 96 persen. Hasil: Efektivitas yang diperoleh dari uji ekstrak kulit buah mahoni (Swietenia mahagoni L) yaitu 29,6 persen,Hasil ekstraksi diperoleh 6,7 persen, pada hasil skrining fitokimia ekstrak kulit buah mahoni diperoleh senyawa flavonoid, saponin, fenolik, tanin dan alkaloid. Hasil efektivitas ekstrak kulit buah mahoni (Switenia mahagoni L) sudah efektiv pada konsentrasi 10 persen dengan zona hambat 8,5 mm yang memiliki respon hambat sedang. Simpulan: Ekstrak etanol kulit buah mahoni (Swietenia mahagoni L) memiliki sifat yang dapat menghambat pertumbuhan bakteri Salmonella typhi. Kata Kunci: Efektivitas; Ekstrak Kulit Buah Mahoni (Swietenia Mahagoni L.); Salmonella Thypi.

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