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Pengaruh kombinasi HIIT berenang dan ekstrak Centella asiatica terhadap kecemasan dan memori pada tikus wistar Qonita Sari Bustomi; Rahma Fithriyatun Nisa; Nisrina Nabila Gunawan; Marvel Lumingkewas; Fairuz Tsuraya Ramadhani; Nisa Kartika Komara
Jurnal SAGO Gizi dan Kesehatan Vol 5, No 3B (2024): Nopember
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v5i3B.2007

Abstract

Background: Neurodegenerative diseases are associated with progressive memory loss and can lead to neuronal cell damage. One consequence of neuronal cell damage is the decline in short-term memory. Changes in short-term memory can be caused by increased levels of anxiety and depression in the elderly, potentially leading to dementia. The antioxidant substances in Centella asiatica and the effects of physical exercise have potential in preventing the decline in anxiety levels and short-term memory.Objectives: to determine the effects of combination of swimming HIIT and Centella asiatica oil extract on anxiety and short-term memory in adult male Wistar rats.Methods: The research method used was a pre-test post-test design with a control group on male Wistar rats. The study was conducted in the Laboratory of the Faculty of Medicine, University of Palangka Raya, from April to July 2024. The sample consisted of 24 rats divided into 4 groups: Control (K1), treatment of swimming HIIT (K2), administration of Centella asiatica Oil Extract (K2), and the combination of swimming HIIT with Centella asiatica Oil (K4). Data analysis was performed using One Way ANOVA, followed by Post Hoc Test with a 95% confidence interval.Results: There is a significant difference in anxiety levels and short-term memory between treatment groups (p= <0,001). Based on these results, the group with the best outcome is the group that received the combination treatment of swimming HIIT and Centella asiatica oil, as evidenced by a significant difference between the combination group and the other groups (p = <0,001).Conclusion: The combination treatment of swimming HIIT and Centella asiatica oil has the best potential for reducing anxiety levels and improving short-term memory in adult male Wistar rats.
Testing the Vitamin B12 Levels in Cassava Tapai Sanchia Cleosha Viorina; Septi Handayani; Nisa Kartika Komara; Nawan Nawan; Ina Arleny
International Journal of Health Engineering and Technology Vol. 4 No. 5 (2026): IJHESS JANUARY 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i5.503

Abstract

Anemia remains a major public health issue in Indonesia, including Central Kalimantan, and is often linked to vitamin B12 deficiency. Vitamin B12 is typically found in animal-based foods; However, certain microorganisms involved in the fermentation of plant-based foods, such as cassava tapai, can synthesize this vitamin. This study aims to determine the vitamin B12 content and its variation in cassava tapai from Palangka Raya City based on fermentation duration. A comparative descriptive study with a quantitative approach was conducted using 16 samples obtained through purposive sampling from four local tapai producers at Pasar Besar A. Yani, Palangka Raya. Vitamin B12 levels were measured using UV-Vis spectrophotometry at 361 nm, and organoleptic properties (color, aroma, taste, texture) were analyzed descriptively. The results showed that all samples contained vitamin B12 ranging from 453,736,666.67 to 1,588,180,000.00 mcg/100g, with levels increasing along with fermentation time (days 1–4). Organoleptic tests revealed non-white color, alcoholic aroma, slightly sweet to unsweet taste, and soft texture. In conclusion, cassava tapai produced by MSMEs in Palangka Raya contains high levels of vitamin B12 and holds promise as a potential local food source to help prevent vitamin B12 deficiency anemia