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All Journal Indonesian Journal of Pure and Applied Chemistry Innovative: Journal Of Social Science Research Jurnal Info Kesehatan
Herlinda Djohan
Department Of Medical Laboratory Technology, Poltekkes Kemenkes Pontianak, Pontianak, West Kalimantan, Indonesia.
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Public Health Other

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ISOLATION OF FLAVONOID FROM ANDONG LEAVES (Cordyline fruticosa (L.) A. Chev.) AND ITS ACTIVITY AS COMPLEXOR OF Fe2+ Herlinda Djohan; Ari Widiyantoro; Anis Shofiyani
Indonesian Journal of Pure and Applied Chemistry Vol 2, No 1 (2019)
Publisher : Tanjungpura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1833.005 KB) | DOI: 10.26418/indonesian.v2i1.36947

Abstract

Flavonoid is one of the phenolic compounds that can complex metals. One of the native plants of Indonesia which has the potential as a metal complexor is the andong plant (Cordyline fruticosa (L.) A.Chev). The isolation process to obtain pure compound are extraction, fractionation, and separation by chromatography. Chromatography method using vacuum liquid chromatography (VLC), gravity column chromatography (GCC) and preparative thin layer chromatography (TLC). This research obtained relatively pure isolate F2.8. The IR (KBr) data on wave numbers of isolate F2.8 were 3430; 2925-2855; 1749; 1609-1512; 1171 and 1100 cm-1.The result of the spectrum 1H-NMR showed flavonoid compound has similar typical spectrum of apigenin compound which showed chemical shift (δH ppm) : 6.85 (1H, s, H-3); 6.29 (1H, s H-6); 6.57 (1H, H-8); 7.03 (2H, d, J = 11.96 Hz, H-3’, H-5’); 8.03 (2H, d, J = 11.72 Hz, H-2’, H-6’). The UV-Vis (CH3OH) spectrum data of isolate F2.8 after the addition of Fe2+ showed a shift at λmax towards a greater direction with a batochromic shift which was caused a decrease in absorbance after the addition of iron (Fe2+) 20 ppm namely: 290 nm; 305 nm with respectively absorbances of 1.62 A; 0.42 A. Based on these data, isolate F2.8 is apigenin which is capable of complexing Fe2+.
Hubungan Kadar HbA1c dan Mikroalbumin Pasien Prolanis Di Kota Pontianak Klara Nora Enola; Herlinda Djohan; Laila Kamilla
Innovative: Journal Of Social Science Research Vol. 3 No. 6 (2023): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v3i6.6558

Abstract

Diabetes Melitus (DM) Tipe 2 merupakan kondisi kelaianan metabolisme dengan hiperglikemi akibat gangguan sensitivitas sel β pankreas untuk hasilkan hormon insulin. Pengendalian DM dilakukan kontrol kadar HbA1c, komplikasi nefropati diabetik digambarkan dengan kadar mikroalbumin. Kontrol rutin ini difasilitasi oleh Prolanis.  Penelitian ini bertujuan untuk mengetahui dan menganalisis hubungan nilai HbA1c dan mikroalbumin pada peserta Prolanis dengan riwayat DM tipe 2 di Kota Pontianak. Penelitian menggunakan metode cross sectional teknik total sampling dengan data rekam medis peserta Prolanis yang memeriksakan diri di UPT Pusat Labkes Kota Pontianak tahun 2022. Analisis dilakukan secara univariate dan bivariate menggunakan uji korelasi Pearson. Dari 70 subjek penelitian didapat hasil kadar HbA1c tidak terkontrol yaitu 87,1% (61 orang) dan dengan mikroalbumin tidak normal 72,9 % (51 orang), hasil uji statistik menunjukkan sig. = 0,914 (>0,05) dengan r = -0,013 (<r tabel) artinya tidak ada hubungan bermakna antara kadar HbA1c dan mikroalbumin peserta Prolanis di Kota Pontianak.
The Effectiveness of Pineapple Extract (Ananas Comosus) and Kesum Leaves (Polygonus Minus) on the Quality of Coconut Oil (Coconus Nucifera) Hendra Budi Sungkawa; Wahdaniah Wahdaniah; Herlinda Djohan
JURNAL INFO KESEHATAN Vol 19 No 2 (2021): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Politeknik Kesehatan Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol19.Iss2.519

Abstract

The processed oil from the coconut plant is generally understood as coconut oil. A method is required to produce a product with a higher oil extraction rate and is able to reduce the water content and free fatty acids in the coconut oil production. It is also necessary to add substances that can delay or prevent fat oxidation reactions by generating substances in the form of antioxidants. The method that can be implemented is the enzymatic method employing the bromelain enzyme in a pineapple with the addition of an antioxidants substance from the kesum leaf. The objective of this research is to describe the quality of coconut oil after the addition of pineapple (ananas comosus) and kesum leaves (polygonus minus) extracts. The parameters for describing the quality of the oil are the organoleptic test, the degree of acidity, the oil extract rate, the peroxide number, the saponification number, and the acid number. This research is a quasi-experiment. The samples in this research were coconut oil without the addition of pineapple fruit extract, coconut oil with the addition of pineapple fruit extract without the addition of kesum leaves, and coconut oil with the addition of pineapple fruit extract and kesum leaves as much as 20gr, 30gr and 40gr. Based on the statistical results of the linear regression test, it was discovered that p-value = 0.000 <0.05, so it was concluded that there was an effect of the addition of pineapple fruit and leaves of kesum on acid number content with an effect of 76.4% on the acid number, 71.4% on the peroxide number, and 81.5% to the saponification number. It is recommended to test the water content, free fatty acids, and iodine number.
Co-Authors Aditia Aditia Affifatuzahara Affifatuzahara Agitya Cita Amanda Anisya Nur Shafitri Ari Nuswantoro Ari Widiyantoro Bagus Muhammad Ihsan Benedikta Anjelica Deara Zanika Intan Pristanty Dyah Yuana Putri Etiek Nurhayati Fahma Ajeng Al-qorifah Hendra Budi Sungkawa Hendra Budi Sungkawa Hendra Budi Sungkawa Ika Sartika Imma Fatayati Klara Nora Enola Laila Kamila Laila Kamilla Linda Triana Maulidiyah Salim nirnadia nirnadia Nisa Kartika Komara Nurul Uq'ma Paula Jaenne Trifani Rizky Astri Wulandari Shofiyani, Anis Silvia Putri Slamet Sri Tumpuk Sri Tumpuk Sugito Sugito Sugito Sugito Sutriswanto Sutriswanto Sutriswanto, Sutriswanto Suwandi, Edy Victorinus Alfino Pratama Wahdaniah Wahdaniah Widya Nurhayati